| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Widodo, Muhammad Sasmito Djati, Muhaimin Rifa'. Role of MicroRNAs in carcinogenesis that potential for biomarker of endometrial cancer. Annals of medicine and surgery (2012). vol 7. 2016-03-23. PMID:27006767. |
some of the genes are pten, gsk3b, and tp53, which are a tumor suppressor that control the process of growth arrest, dna repair, and apoptosis. |
2016-03-23 |
2023-08-13 |
Not clear |
| Widodo, Muhammad Sasmito Djati, Muhaimin Rifa'. Role of MicroRNAs in carcinogenesis that potential for biomarker of endometrial cancer. Annals of medicine and surgery (2012). vol 7. 2016-03-23. PMID:27006767. |
moreover, hsa-mir-181d was upregulated to control expression a tumor suppressor gene, pten to protect the cancer cell from apoptosis. |
2016-03-23 |
2023-08-13 |
Not clear |
| Di-Fei Wang, Hui-Jing Yang, Jian-Qiu Gu, Yan-Li Cao, Xin Meng, Xiao-Li Wang, Yi-Chen Lin, Ming Ga. Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25962562. |
by contrast, the expression of pten and p-pten as well as apoptosis were significantly increased. |
2016-03-10 |
2023-08-13 |
Not clear |
| Di-Fei Wang, Hui-Jing Yang, Jian-Qiu Gu, Yan-Li Cao, Xin Meng, Xiao-Li Wang, Yi-Chen Lin, Ming Ga. Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25962562. |
following treatment with bisperoxopicolinatooxovanadate (bpv) or metformin in the insulin-resistant skeletal muscle cells, there was an increase in the rate of glucose uptake, an increase in glut4 expression and its translocation, a reduction in the expression of pten and p-pten, and a decrease in cell apoptosis compared with untreated insulin-resistant cells. |
2016-03-10 |
2023-08-13 |
Not clear |
| Di-Fei Wang, Hui-Jing Yang, Jian-Qiu Gu, Yan-Li Cao, Xin Meng, Xiao-Li Wang, Yi-Chen Lin, Ming Ga. Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25962562. |
cells with glucosamine-induced insulin-resistance exhibited a reduced expression of glut4 and dysfunction in glut4 translocation, as well as increased activation of pten and increased cell apoptosis. |
2016-03-10 |
2023-08-13 |
Not clear |
| Di-Fei Wang, Hui-Jing Yang, Jian-Qiu Gu, Yan-Li Cao, Xin Meng, Xiao-Li Wang, Yi-Chen Lin, Ming Ga. Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25962562. |
inhibition of pten or its upstream regulator, ampk, protects glucosamine-induced insulin-resistant skeletal muscle cells from apoptosis. |
2016-03-10 |
2023-08-13 |
Not clear |
| Jun Chen, He Zhu, Yan Zhang, Man-Hua Cui, Li-Ying Han, Zhan-Hui Jia, Ling Wang, Hong Teng, Li-Ning Mia. Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway. Molecular medicine reports. vol 12. issue 2. 2016-03-04. PMID:25954860. |
knockdown of pten in the ccrcc cell line achn blocked etoposide-induced apoptosis and etoposide-impaired cell proliferation was also inhibited. |
2016-03-04 |
2023-08-13 |
Not clear |
| Bodo C Melni. MiR-21: an environmental driver of malignant melanoma? Journal of translational medicine. vol 13. 2016-03-02. PMID:26116372. |
mir-21 is an oncomir that affects critical target genes of malignant melanoma, resulting in sustained proliferation (pten, pi3k, sprouty, pdcd4, foxo1, tipe2, p53, cyclin d1), evasion from apoptosis (foxo1, fbxo11, apaf1, timp3, tipe2), genetic instability (msh2, fbxo11, htert), increased oxidative stress (foxo1), angiogenesis (pten, hif1α, timp3), invasion and metastasis (apaf1, pten, pdcd4, timp3). |
2016-03-02 |
2023-08-13 |
Not clear |
| Dan Xiong, Yunlin Ye, Yujie Fu, Jinglong Wang, Bohua Kuang, Hongbo Wang, Xiumin Wang, Lidong Zu, Gang Xiao, Mingang Hao, Jianhua Wan. Bmi-1 expression modulates non-small cell lung cancer progression. Cancer biology & therapy. vol 16. issue 5. 2016-03-01. PMID:25880371. |
we find that bmi-1 does not affect cell cycle and apoptosis in lung cancer cell lines as it does not affect the expression of p16/p19, pten, akt and p-akt. |
2016-03-01 |
2023-08-13 |
Not clear |
| Jingwei Li, Kailei Jiang, Fujie Zha. Icariin regulates the proliferation and apoptosis of human ovarian cancer cells through microRNA-21 by targeting PTEN, RECK and Bcl-2. Oncology reports. vol 33. issue 6. 2016-02-09. PMID:25845681. |
icariin regulates the proliferation and apoptosis of human ovarian cancer cells through microrna-21 by targeting pten, reck and bcl-2. |
2016-02-09 |
2023-08-13 |
human |
| Jingwei Li, Kailei Jiang, Fujie Zha. Icariin regulates the proliferation and apoptosis of human ovarian cancer cells through microRNA-21 by targeting PTEN, RECK and Bcl-2. Oncology reports. vol 33. issue 6. 2016-02-09. PMID:25845681. |
notably, mir-21 regulated the potential anticancer effects of icariin on cell proliferation and apoptosis by targeting pten, reck and bcl-2 in the ovarian cancer a2780 cells. |
2016-02-09 |
2023-08-13 |
human |
| K Yao, H C Xing, B Wu, Y Li, A J Liao, W Yang, Z G Li. Effect of TIEG1 on apoptosis and expression of Bcl-2/Bax and Pten in leukemic cell lines. Genetics and molecular research : GMR. vol 14. issue 1. 2016-02-08. PMID:25867342. |
effect of tieg1 on apoptosis and expression of bcl-2/bax and pten in leukemic cell lines. |
2016-02-08 |
2023-08-13 |
Not clear |
| K Yao, H C Xing, B Wu, Y Li, A J Liao, W Yang, Z G Li. Effect of TIEG1 on apoptosis and expression of Bcl-2/Bax and Pten in leukemic cell lines. Genetics and molecular research : GMR. vol 14. issue 1. 2016-02-08. PMID:25867342. |
we examined the effect of transforming growth factor-b inducible early gene-1 (tieg1) on the apoptosis of leukemic cell lines and expression of b-cell lymphoma 2 (bcl-2) and phosphatase and tensin homolog (pten). |
2016-02-08 |
2023-08-13 |
Not clear |
| K Yao, H C Xing, B Wu, Y Li, A J Liao, W Yang, Z G Li. Effect of TIEG1 on apoptosis and expression of Bcl-2/Bax and Pten in leukemic cell lines. Genetics and molecular research : GMR. vol 14. issue 1. 2016-02-08. PMID:25867342. |
during apoptosis induction, the expression of bcl-2 was decreased and the expressions of bax and pten were increased in the 4 leukemic cell lines induced by tieg1 (p < 0.05). |
2016-02-08 |
2023-08-13 |
Not clear |
| K Yao, H C Xing, B Wu, Y Li, A J Liao, W Yang, Z G Li. Effect of TIEG1 on apoptosis and expression of Bcl-2/Bax and Pten in leukemic cell lines. Genetics and molecular research : GMR. vol 14. issue 1. 2016-02-08. PMID:25867342. |
a close relationship exists between bcl-2/bax and pten expression and cell apoptosis induced by tieg1. |
2016-02-08 |
2023-08-13 |
Not clear |
| Yan Sun, Hua Tian, Lin Wan. Effects of PTEN on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/Akt pathway. Oncology reports. vol 33. issue 4. 2016-02-04. PMID:25683168. |
effects of pten on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/akt pathway. |
2016-02-04 |
2023-08-13 |
Not clear |
| Yan Sun, Hua Tian, Lin Wan. Effects of PTEN on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/Akt pathway. Oncology reports. vol 33. issue 4. 2016-02-04. PMID:25683168. |
lovo and sw480 cells with upregulated pten were sensitive to apoptosis induced by 5-fu. |
2016-02-04 |
2023-08-13 |
Not clear |
| Maryam Esfahani, Negar Ataei, Mojtaba Panjehpou. Biomarkers for evaluation of prostate cancer prognosis. Asian Pacific journal of cancer prevention : APJCP. vol 16. issue 7. 2016-01-26. PMID:25854335. |
we here selected a group of candidate biomarkers including psa, psa velocity, percentage free psa, tgfβ1, amacr, chromogranin a, il-6, igfbps, psca, biomarkers related to cell cycle regulation, apoptosis, pten, androgen receptor, cellular adhesion and angiogenesis, and also prognostic biomarkers with genomic tests for discussion. |
2016-01-26 |
2023-08-13 |
Not clear |
| Qian Hou, Minxiang Lei, Ke Hu, Min Wan. The effects of high glucose levels on reactive oxygen species-induced apoptosis and involved signaling in human vascular endothelial cells. Cardiovascular toxicology. vol 15. issue 2. 2016-01-15. PMID:25158671. |
silencing nox4 and pten gene expression and inhibiting caspase-3 activation significantly protected huvecs from glucose-induced cell apoptosis. |
2016-01-15 |
2023-08-13 |
human |
| Angela Bononi, Paolo Pinto. Study of PTEN subcellular localization. Methods (San Diego, Calif.). vol 77-78. 2016-01-15. PMID:25312582. |
the repertoire of roles fulfilled by pten has recently been expanded to include crucial functions in the nucleus, where it favors genomic stability and restrains cell cycle progression, as well as protein phosphatase dependent activity at the endoplasmic reticulum (er) and mitochondria-associated membranes (mams), where pten interacts with the inositol 1,4,5-trisphosphate receptors (ip3rs) and regulates ca(2+) release from the er and sensitivity to apoptosis. |
2016-01-15 |
2023-08-13 |
Not clear |