| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weigang Cui, Yinghua Zhang, Chenxi Yang, Yiyuan Sun, Min Zhang, Songtao Wan. Hydrogen sulfide prevents Abeta-induced neuronal apoptosis by attenuating mitochondrial translocation of PTEN. Neuroscience. vol 325. 2017-06-07. PMID:27026591. |
in conclusion, these data indicate that h(2)s inhibits aβ-induced neuronal apoptosis by attenuating mitochondrial translocation of pten and that activation of pi3k/akt signaling pathway plays a critical role in h(2)s-mediated neuronal protection. |
2017-06-07 |
2023-08-13 |
Not clear |
| Jiangyou Wang, Han Chen, You Zhou, Qiang Su, Tao Liu, Lang L. Levosimendan Pretreatment Inhibits Myocardial Apoptosis in Swine after Coronary Microembolization. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 41. issue 1. 2017-06-06. PMID:28214866. |
phosphatase and tensin homolog deleted on chromosome ten (pten) has been revealed to be up-regulated in circumstances of coronary microembolization (cme), and the pten signaling pathway mediates myocardial apoptosis in swine after cme. |
2017-06-06 |
2023-08-13 |
Not clear |
| Shanwei Mi, Gang Xiang, Daolu Yuwen, Jian Gao, Wenjie Guo, Xuefeng Wu, Xudong Wu, Yang Sun, Yongqian Su, Yan Shen, Qiang X. Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway. Toxicology and applied pharmacology. vol 310. 2017-05-31. PMID:27639426. |
andrographolide, a natural diterpenoid, promoted the activation of the akt/mtor signaling by downregulating pten and suppressed autophagy, which subsequently resensitized the resistant cells to cisplatin-mediated apoptosis. |
2017-05-31 |
2023-08-13 |
Not clear |
| Ming Tu, Lin Cai, Weiming Zheng, Zhipeng Su, Yong Chen, Songtao Q. CD164 regulates proliferation and apoptosis by targeting PTEN in human glioma. Molecular medicine reports. vol 15. issue 4. 2017-05-22. PMID:28259931. |
cd164 regulates proliferation and apoptosis by targeting pten in human glioma. |
2017-05-22 |
2023-08-13 |
human |
| Bing Wang, Dongqi Wang, Tao Yan, Huijun Yua. MiR-138-5p promotes TNF-α-induced apoptosis in human intervertebral disc degeneration by targeting SIRT1 through PTEN/PI3K/Akt signaling. Experimental cell research. vol 345. issue 2. 2017-05-19. PMID:27207584. |
furthermore, inhibition of mir-138-5p downregulated pten protein expression and promoted activation of pi3k/akt, and knockdown of either sirt1 or the pi3k/akt inhibitor (ly294002) abolished the effect of mir-138-5p on np cell apoptosis. |
2017-05-19 |
2023-08-13 |
human |
| Juan Zhang, Ke Chen, Linghao Wang, Xinxin Wan, Chandrama Shrestha, Jingsong Zhou, Zhaohui M. Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy. Biochemical and biophysical research communications. vol 476. issue 4. 2017-05-12. PMID:27233610. |
phosphatase and tensin homologue (pten)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy. |
2017-05-12 |
2023-08-13 |
rat |
| Xuemin Niu, Na Fu, Jinghua Du, Rongqi Wang, Yang Wang, Suxian Zhao, Huijuan Du, Baoyu Wang, Yuguo Zhang, Dianxing Sun, Yuemin Na. miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis. FEBS letters. vol 590. issue 16. 2017-05-09. PMID:27423040. |
mir-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting pten in hcv-related liver fibrosis. |
2017-05-09 |
2023-08-13 |
Not clear |
| Xuemin Niu, Na Fu, Jinghua Du, Rongqi Wang, Yang Wang, Suxian Zhao, Huijuan Du, Baoyu Wang, Yuguo Zhang, Dianxing Sun, Yuemin Na. miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis. FEBS letters. vol 590. issue 16. 2017-05-09. PMID:27423040. |
overexpression of mir-1273g-3p could inhibit translation of pten, increase the expression of α-sma, col1a1, and reduce apoptosis in hscs. |
2017-05-09 |
2023-08-13 |
Not clear |
| Xuemin Niu, Na Fu, Jinghua Du, Rongqi Wang, Yang Wang, Suxian Zhao, Huijuan Du, Baoyu Wang, Yuguo Zhang, Dianxing Sun, Yuemin Na. miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis. FEBS letters. vol 590. issue 16. 2017-05-09. PMID:27423040. |
hence, we conclude that mir-1273g-3p might affect the activation and apoptosis of hscs by directly targeting pten in hcv-related liver fibrosis. |
2017-05-09 |
2023-08-13 |
Not clear |
| Wenting Huang, Chao Quan, Peng Duan, Sha Tang, Wei Chen, Kedi Yan. Nonylphenol induced apoptosis and autophagy involving the Akt/mTOR pathway in prepubertal Sprague-Dawley male rats in vivo and in vitro. Toxicology. vol 373. 2017-05-08. PMID:27832966. |
np induced a reduction in testosterone (15.58%, 17.23%, 13.38% in 25, 50, 100mg/kg group, respectively), triggered apoptosis related to oxidative stress, and disturbed mrna and/or protein levels of pi3k, pten, pdk1, p-akt, p-mtor, p70s6k, caspase-3, lc3b. |
2017-05-08 |
2023-08-13 |
rat |
| Juan Lv, Qiaoying Zhu, Xuemei Jia, Ningzhu Yu, Qian L. In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental Study. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-05-03. PMID:27744455. |
the aim of this study was to investigate the role and significance of pten protein in the occurrence, development, and treatment of endometriosis through changes in apoptosis rate, cell cycle, and angiogenesis. |
2017-05-03 |
2023-08-13 |
mouse |
| Juan Lv, Qiaoying Zhu, Xuemei Jia, Ningzhu Yu, Qian L. In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental Study. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-05-03. PMID:27744455. |
the changes in cell cycle and apoptosis in the different pten expression groups were evaluated using flow cytometry. |
2017-05-03 |
2023-08-13 |
mouse |
| Juan Lv, Qiaoying Zhu, Xuemei Jia, Ningzhu Yu, Qian L. In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental Study. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-05-03. PMID:27744455. |
results pten overexpression significantly increased apoptosis and inhibited the cell cycle compared with the silenced and control groups. |
2017-05-03 |
2023-08-13 |
mouse |
| Juan Lv, Qiaoying Zhu, Xuemei Jia, Ningzhu Yu, Qian L. In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental Study. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-05-03. PMID:27744455. |
conclusions pten inhibits the occurrence and development of endometriosis by regulating angiogenesis and the apoptosis and cell cycle of endometrial cells; therefore, we propose that the pten gene can be used to treat endometriosis. |
2017-05-03 |
2023-08-13 |
mouse |
| Feng Yang, Wenwei Liu, Xiaojuan Yan, Hanyun Zhou, Hongshen Zhang, Jianfei Liu, Ming Yu, Xiaoshan Zhu, Kezhong M. Effects of mir-21 on Cardiac Microvascular Endothelial Cells After Acute Myocardial Infarction in Rats: Role of Phosphatase and Tensin Homolog (PTEN)/Vascular Endothelial Growth Factor (VEGF) Signal Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-05-02. PMID:27708252. |
in addition, lenti-pten and vegf sirna were transfected into cmec cells using standard procedures for assessing the effect of pten and vege on cell proliferation, apoptosis, and angiogenesis. |
2017-05-02 |
2023-08-13 |
rat |
| Jie Xiao, Weifeng Yu, Kongzu Hu, Maoqiang Li, Jianwei Chen, Zhanchun L. miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway. Oncology reports. vol 37. issue 4. 2017-04-17. PMID:28260104. |
furthermore, pten knockdown abrogated the functional effects of mir-92a silencing on the proliferation, apoptosis and cell cycle progression in os cells. |
2017-04-17 |
2023-08-13 |
mouse |
| J P Loftus, D Cavatorta, J J Bushey, C B Levine, C S Sevier, J J Wakshla. The 5-lipoxygenase inhibitor tepoxalin induces oxidative damage and altered PTEN status prior to apoptosis in canine osteosarcoma cell lines. Veterinary and comparative oncology. vol 14. issue 2. 2017-04-13. PMID:24813477. |
the 5-lipoxygenase inhibitor tepoxalin induces oxidative damage and altered pten status prior to apoptosis in canine osteosarcoma cell lines. |
2017-04-13 |
2023-08-13 |
Not clear |
| Pan Huang, Zhengrong Zhou, Fangxiong Shi, Genbao Shao, Ran Wang, Jintian Wang, Kangxin Wang, Wei Din. Effects of the IGF-1/PTEN/Akt/FoxO signaling pathway on male reproduction in rats subjected to water immersion and restraint stress. Molecular medicine reports. vol 14. issue 6. 2017-04-07. PMID:27779666. |
in addition, the expression levels and immunolocalization of igf‑1, pten, akt and foxo proteins, as well as the rate of cell apoptosis in rat testes, were investigated. |
2017-04-07 |
2023-08-13 |
rat |
| Yangyang Cai, Tao He, Lidan Liang, Xin Zhang, Hongying Yua. Upregulation of microRNA‑337 promotes the proliferation of endometrial carcinoma cells via targeting PTEN. Molecular medicine reports. vol 13. issue 6. 2017-04-06. PMID:27082228. |
ec cells transfected with mir‑337 mimics and anti‑pten small interfering rna demonstrated significantly decreased expression of pten, markedly increased proliferation and inhibition of cell apoptosis. |
2017-04-06 |
2023-08-13 |
Not clear |
| Shi Liu, Zhong-Ling Xu, Li Sun, Ying Liu, Cheng-Chong Li, Hong-Mei Li, Wei Zhang, Cheng-Jun Li, Wei Qi. (‑)‑Epigallocatechin‑3‑gallate induces apoptosis in human pancreatic cancer cells via PTEN. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27176210. |
(‑)‑epigallocatechin‑3‑gallate induces apoptosis in human pancreatic cancer cells via pten. |
2017-04-06 |
2023-08-13 |
human |