| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Zhang Wang, Xiang-Hua Lin, Qiao-Hong Pu, Man-Yu Liu, Li Li, Li-Rong Wu, Qing-Qing Wu, Jian-Wen Mao, Jia-Yong Zhu, Xiao-Bao Ji. Targeting miR-21 sensitizes Ph+ ALL Sup-b15 cells to imatinib-induced apoptosis through upregulation of PTEN. Biochemical and biophysical research communications. vol 454. issue 3. 2017-09-18. PMID:25451263. |
targeting mir-21 sensitizes ph+ all sup-b15 cells to imatinib-induced apoptosis through upregulation of pten. |
2017-09-18 |
2023-08-13 |
Not clear |
| Wei-Zhang Wang, Xiang-Hua Lin, Qiao-Hong Pu, Man-Yu Liu, Li Li, Li-Rong Wu, Qing-Qing Wu, Jian-Wen Mao, Jia-Yong Zhu, Xiao-Bao Ji. Targeting miR-21 sensitizes Ph+ ALL Sup-b15 cells to imatinib-induced apoptosis through upregulation of PTEN. Biochemical and biophysical research communications. vol 454. issue 3. 2017-09-18. PMID:25451263. |
transient inhibition of mir-21 resulted in increased apoptosis, pten upregulation and akt dephosphorylation, whereas ectopic overexpression of mir-21 further conferred imatinib resistance. |
2017-09-18 |
2023-08-13 |
Not clear |
| Wei-Zhang Wang, Xiang-Hua Lin, Qiao-Hong Pu, Man-Yu Liu, Li Li, Li-Rong Wu, Qing-Qing Wu, Jian-Wen Mao, Jia-Yong Zhu, Xiao-Bao Ji. Targeting miR-21 sensitizes Ph+ ALL Sup-b15 cells to imatinib-induced apoptosis through upregulation of PTEN. Biochemical and biophysical research communications. vol 454. issue 3. 2017-09-18. PMID:25451263. |
furthermore, knockdown of pten protected the cells from imatinib-induced apoptosis achieved by inhibition of mir-21. |
2017-09-18 |
2023-08-13 |
Not clear |
| Xu-Hua Mao, Min Chen, Yan Wang, Pan-Gen Cui, Si-Bian Liu, Zei-Yong X. MicroRNA-21 regulates the ERK/NF-κB signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma A375 cells by targeting SPRY1, PDCD4, and PTEN. Molecular carcinogenesis. vol 56. issue 3. 2017-09-05. PMID:27533779. |
microrna-21 regulates the erk/nf-κb signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma a375 cells by targeting spry1, pdcd4, and pten. |
2017-09-05 |
2023-08-13 |
human |
| Xu-Hua Mao, Min Chen, Yan Wang, Pan-Gen Cui, Si-Bian Liu, Zei-Yong X. MicroRNA-21 regulates the ERK/NF-κB signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma A375 cells by targeting SPRY1, PDCD4, and PTEN. Molecular carcinogenesis. vol 56. issue 3. 2017-09-05. PMID:27533779. |
mir-21 can promote the proliferation, migration, and inhibit the apoptosis of human melanoma a375 cells by inhibiting spry1, pdcd4, and pten via erk/nf-κb signaling pathway. |
2017-09-05 |
2023-08-13 |
human |
| Jingna Su, Xiuxia Zhou, Xuyuan Yin, Lixia Wang, Zhe Zhao, Yingying Hou, Nana Zheng, Jun Xia, Zhiwei Wan. The effects of curcumin on proliferation, apoptosis, invasion, and NEDD4 expression in pancreatic cancer. Biochemical pharmacology. vol 140. 2017-08-18. PMID:28535906. |
we found that curcumin inhibited cell proliferation and triggered apoptosis in pc, which is associated with increased expression of pten and p73. |
2017-08-18 |
2023-08-13 |
human |
| Xiao-Feng Wu, Zi-Hui Zhou, Jian Zo. MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 95. issue 3. 2017-08-15. PMID:28177757. |
microrna-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting pten. |
2017-08-15 |
2023-08-13 |
Not clear |
| Xiao-Feng Wu, Zi-Hui Zhou, Jian Zo. MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 95. issue 3. 2017-08-15. PMID:28177757. |
to investigate the effects of microrna-181 (mir-181) on the proliferation and apoptosis of chondrocytes in osteoarthritis (oa) by targeting pten. |
2017-08-15 |
2023-08-13 |
Not clear |
| Xuan Li, Yan-Kui Wang, Zhi-Qiang Song, Zhi-Qiang Du, Cai-Xia Yan. Dimethyl Sulfoxide Perturbs Cell Cycle Progression and Spindle Organization in Porcine Meiotic Oocytes. PloS one. vol 11. issue 6. 2017-07-24. PMID:27348312. |
3% dmso treatment did not affect expression of genes involved in spindle organization (bub1 and mad2) and apoptosis (nf-κb, pten, bcl2, caspase3 and caspase9), however, it significantly decreased expression levels of pluripotency genes (oct4, sox2 and lin28) in mature oocytes. |
2017-07-24 |
2023-08-13 |
mouse |
| Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping La. Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. International journal of oncology. vol 49. issue 4. 2017-07-13. PMID:27499479. |
upregulation of microrna-370 promotes cell apoptosis and inhibits proliferation by targeting pten in human gastric cancer. |
2017-07-13 |
2023-08-13 |
human |
| Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping La. Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. International journal of oncology. vol 49. issue 4. 2017-07-13. PMID:27499479. |
accumulating evidence reported that pten signaling pathway plays an important role in the cellular processes, such as apoptosis, cell growth and proliferation. |
2017-07-13 |
2023-08-13 |
human |
| Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping La. Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. International journal of oncology. vol 49. issue 4. 2017-07-13. PMID:27499479. |
our study indicated that mir‑370 targeted pten leading to activation of apoptosis signaling and the cell proliferation of cervical cancer cells, ameliorating gastric cancer growth and progression. |
2017-07-13 |
2023-08-13 |
human |
| Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping La. Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. International journal of oncology. vol 49. issue 4. 2017-07-13. PMID:27499479. |
in addition, the combination of mir‑370 and pten inactivated akt, mdm2 and mtor while stimulated caspase-3, p53 and gsk3β expression, promoting apoptosis and suppressing proliferation of gastric cancer cells. |
2017-07-13 |
2023-08-13 |
human |
| Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping La. Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. International journal of oncology. vol 49. issue 4. 2017-07-13. PMID:27499479. |
therefore, our study revealed the mechanistic links between mir‑370 and pten in the pathogenesis of gastric cancer through modulation of cell apoptosis and proliferation. |
2017-07-13 |
2023-08-13 |
human |
| Yiying Wu, Xing Zhang, Zhengzhao Li, Haibiao Yan, Jian Qin, Tianyu L. Formononetin inhibits human bladder cancer cell proliferation and invasiveness via regulation of miR-21 and PTEN. Food & function. vol 8. issue 3. 2017-07-10. PMID:28139790. |
t24 cells were treated with different concentrations of formononetin, and then the cell proliferation was assessed by mtt assay, cell apoptosis by hoechst 33258 stain assay, cell invasiveness by transwell invasion assay, microrna-21 (mir-21) expression by real-time pcr and the protein level of phosphatase and tensin homolog (pten) and phosphorylated homolog of akt (p-akt) by western blotting. |
2017-07-10 |
2023-08-13 |
human |
| J Z Zhao, X Q Zheng, M Ga. [Research progress of suppressor gene PTEN]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. vol 51. issue 10. 2017-06-28. PMID:27765117. |
pten regulates the multiple biological processes such as cell proliferation, invasion, metastasis, apoptosis and stem cell self-renewal through the phosphatidylinositol 3-kinase/ protein kinase b signaling pathway. |
2017-06-28 |
2023-08-13 |
Not clear |
| Ayesha Khalid, Tabinda Hussain, Sobia Manzoor, Muhammad Saalim, Saba Khali. PTEN: A potential prognostic marker in virus-induced hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 6. 2017-06-22. PMID:28621226. |
in perspective of the crucial role pten plays in balancing proliferation and apoptosis, we propose pten as a valuable marker in the diagnosis, assessment of tumor grade, and disease stage in hepatocellular carcinoma patients. |
2017-06-22 |
2023-08-13 |
Not clear |
| Bin Wang, Jie Yang, Bin Xia. MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression. PloS one. vol 11. issue 10. 2017-06-19. PMID:27701465. |
mir-20b upregulation promoted cell proliferation, migration, invasiveness, and tumor growth, and decreased apoptosis, and reduced pten protein level but not mrna expression in eca-109 cells. |
2017-06-19 |
2023-08-13 |
Not clear |
| Di Zhao, Youbin Chen, Shunliang Chen, Chuangyi Zheng, Jun Hu, Shaowei Lu. MiR-19a regulates the cell growth and apoptosis of osteosarcoma stem cells by targeting PTEN. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 5. 2017-06-13. PMID:28475001. |
mir-19a regulates the cell growth and apoptosis of osteosarcoma stem cells by targeting pten. |
2017-06-13 |
2023-08-13 |
human |
| Weigang Cui, Yinghua Zhang, Chenxi Yang, Yiyuan Sun, Min Zhang, Songtao Wan. Hydrogen sulfide prevents Abeta-induced neuronal apoptosis by attenuating mitochondrial translocation of PTEN. Neuroscience. vol 325. 2017-06-07. PMID:27026591. |
hydrogen sulfide prevents abeta-induced neuronal apoptosis by attenuating mitochondrial translocation of pten. |
2017-06-07 |
2023-08-13 |
Not clear |