| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongchao Zhou, Yuting Zhang, Jingjing Wang, Yuchao Yan, Yi Liu, Xiaojie Shi, Qi Zhang, Xingang X. The CREB and AP-1-Dependent Cell Communication Network Factor 1 Regulates Porcine Epidemic Diarrhea Virus-Induced Cell Apoptosis Inhibiting Virus Replication Through the p53 Pathway. Frontiers in microbiology. vol 13. 2022-04-14. PMID:35418961. |
the treatment of pft-α (p53 inhibitor) significantly suppressed the expression of cleaved caspase 9 and caspase 3, leading to the decrease of apoptosis. |
2022-04-14 |
2023-08-13 |
Not clear |
| Hongchao Zhou, Yuting Zhang, Jingjing Wang, Yuchao Yan, Yi Liu, Xiaojie Shi, Qi Zhang, Xingang X. The CREB and AP-1-Dependent Cell Communication Network Factor 1 Regulates Porcine Epidemic Diarrhea Virus-Induced Cell Apoptosis Inhibiting Virus Replication Through the p53 Pathway. Frontiers in microbiology. vol 13. 2022-04-14. PMID:35418961. |
overexpression of ccn1 promotes apoptosis by elevating p53 protein phosphorylation and inhibits pedv replication, and knockdown of ccn1 inhibits apoptosis by decreasing p53 protein phosphorylation and promotes pedv replication. |
2022-04-14 |
2023-08-13 |
Not clear |
| D P Berezovskiy, M V Fedulova, D V Gornostaev, H A Avanesyan, V N Borshchevskaya, Yu I Pigolki. [Morphofunctional characteristics of the heart in sudden death of children under 1 year of age in the forensic medical aspect]. Sudebno-meditsinskaia ekspertiza. vol 65. issue 2. 2022-04-13. PMID:35416007. |
an immunohistochemical study revealed a mild over expression of p53 in cellular elements, small-focal expression of cd68 in cardiomyocytes apoptosis intramural areas, activation of mast cells (cd117), expression of ki-67 in macrophages, proliferation of fibroblasts. |
2022-04-13 |
2023-08-13 |
Not clear |
| F Abid, M Saleem, T Leghari, I Rafi, T Maqbool, F Fatima, A M Arshad, S Khurshid, S Naz, F Hadi, M Tahir, S Akhtar, S Yasir, A Mobashar, M Ashra. Evaluation of in vitro anticancer potential of pharmacological ethanolic plant extracts Acacia modesta and Opuntia monocantha against liver cancer cells. Brazilian journal of biology = Revista brasleira de biologia. vol 84. 2022-04-13. PMID:35416847. |
for the evaluation of apoptosis elisa of p53 performed. |
2022-04-13 |
2023-08-13 |
cat |
| F Abid, M Saleem, T Leghari, I Rafi, T Maqbool, F Fatima, A M Arshad, S Khurshid, S Naz, F Hadi, M Tahir, S Akhtar, S Yasir, A Mobashar, M Ashra. Evaluation of in vitro anticancer potential of pharmacological ethanolic plant extracts Acacia modesta and Opuntia monocantha against liver cancer cells. Brazilian journal of biology = Revista brasleira de biologia. vol 84. 2022-04-13. PMID:35416847. |
elisa of p53 for cellular apoptosis showed more release of p53 in treated groups. |
2022-04-13 |
2023-08-13 |
cat |
| M Carmen Lafita-Navarro, Maralice Conacci-Sorrel. Nucleolar stress: From development to cancer. Seminars in cell & developmental biology. 2022-04-12. PMID:35410715. |
this phenomenon, known as nucleolar stress, can lead to molecular changes such as stabilization of p53, which in turn activates cell cycle arrest or apoptosis. |
2022-04-12 |
2023-08-13 |
Not clear |
| Gaolong Zhong, Gan Rao, Lixuan Tang, Shaofeng Wu, Zhaoxin Tang, Riming Huang, Zhiyan Ruan, Lianmei H. Combined effect of arsenic and polystyrene-nanoplastics at environmentally relevant concentrations in mice liver: Activation of apoptosis, pyroptosis and excessive autophagy. Chemosphere. 2022-04-12. PMID:35413363. |
meanwhile, co-treatment with as and psnps induced apoptosis in the liver, which was confirmed by ultrastructure observation and changes in the expression of apoptosis indicators (p53, bax, bcl-2, caspase-3, caspase-9, cleaved-caspase-3 and cytc). |
2022-04-12 |
2023-08-13 |
mouse |
| E Iscan, G Karakülah, U Ekin, M Ozturk, H Uzuner, A Sune. [TAp73α is Upregulated in the Most Common Human Cancers]. Molekuliarnaia biologiia. vol 56. issue 2. 2022-04-11. PMID:35403622. |
the transcription factor p73 is a member of the p53 tumor suppressor gene family and one of the key regulators of apoptosis. |
2022-04-11 |
2023-08-13 |
human |
| Carlos Anerillas, Allison B Herman, Martina Rossi, Rachel Munk, Elin Lehrmann, Jennifer L Martindale, Chang-Yi Cui, Kotb Abdelmohsen, Supriyo De, Myriam Gorosp. Early SRC activation skews cell fate from apoptosis to senescence. Science advances. vol 8. issue 14. 2022-04-08. PMID:35394839. |
with high dna damage, failure to activate src led to elevation of p53, inhibition of p38, and apoptosis. |
2022-04-08 |
2023-08-13 |
mouse |
| Miharu Hisaoka, Johanna Schott, Toman Bortecen, Doris Lindner, Jeroen Krijgsveld, Georg Stoeckli. Preferential translation of p53 target genes. RNA biology. vol 19. issue 1. 2022-04-07. PMID:35388737. |
the transcription factor p53 exerts its tumour suppressive effect through transcriptional activation of numerous target genes controlling cell cycle arrest, apoptosis, cellular senescence and dna repair. |
2022-04-07 |
2023-08-13 |
Not clear |
| Nidhi Nigam, Jasmine George, Smita Srivastava, Preeti Roy, Kulpreet Bhui, Madhulika Singh, Yogeshwer Shukl. Editorial Expression of Concern for: Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis. Cancer chemotherapy and pharmacology. 2022-04-06. PMID:35381876. |
editorial expression of concern for: induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in b[a]p-induced mouse skin tumorigenesis. |
2022-04-06 |
2023-08-13 |
mouse |
| David Hoyos, Benjamin Greenbaum, Arnold J Levin. The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein. Cell death and differentiation. 2022-04-06. PMID:35383292. |
among the protein-protein interaction sites identified by hotspot mutations were mdm-2, a negative regulator of p53, xaf-1, promoting p53 mediated apoptosis, and pin-1, a proline isomerase essential for structural folding of this domain. |
2022-04-06 |
2023-08-13 |
human |
| Xiaofang Wei, Juan Tan, Hui Ga. Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway. Bioengineered. vol 13. issue 4. 2022-04-06. PMID:35383535. |
in addition, this overexpression increased the viability, inhibited apoptosis, and reduced the expression of p53, bax, and cytochrome c, while increasing the expression of bcl-xl in cultured neurons. |
2022-04-06 |
2023-08-13 |
rat |
| Brandon Valafar, Apostolos Zaravinos, Benjamin Bonavid. Cross Talk between the Circadian Clock Proteins and TP53 in Cancer and Therapeutic Significance. Critical reviews in oncogenesis. vol 26. issue 4. 2022-04-05. PMID:35381145. |
the clock genes impact several cancer-related signaling trajectories, including the tumor suppressor's p53 pathway involvement in the regulation of the cell cycle and apoptosis. |
2022-04-05 |
2023-08-13 |
human |
| Brandon Valafar, Apostolos Zaravinos, Benjamin Bonavid. Cross Talk between the Circadian Clock Proteins and TP53 in Cancer and Therapeutic Significance. Critical reviews in oncogenesis. vol 26. issue 4. 2022-04-05. PMID:35381145. |
such therapies will complement a large number of currently tested treatments targeting the restoration of wild-type p53 to prevent tumor growth and lead cancer cells to apoptosis. |
2022-04-05 |
2023-08-13 |
human |
| Gan Rao, Gaolong Zhong, Ting Hu, Shaofeng Wu, Jiajia Tan, Xiaoyong Zhang, Riming Huang, Zhaoxin Tang, Lianmei H. Arsenic Trioxide Triggers Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis via Nrf 2/Caspase 3 Signaling Pathway in Heart of Ducks. Biological trace element research. 2022-04-03. PMID:35366752. |
at the same time, ato induced apoptosis which not only upregulated the expression levels of mrna and proteins (caspase 3, cyt-c, p53, bax) but also decreased the mrna and protein expression level of bcl-2. |
2022-04-03 |
2023-08-13 |
human |
| Mir Mohd Faheem, Madhulika Bhagat, Pooja Sharma, Rythem Anan. Induction of p53 mediated mitochondrial apoptosis and cell cycle arrest in human breast cancer cells by plant mediated synthesis of silver nanoparticles from Bergenia ligulata (Whole plant). International journal of pharmaceutics. 2022-04-03. PMID:35367334. |
induction of p53 mediated mitochondrial apoptosis and cell cycle arrest in human breast cancer cells by plant mediated synthesis of silver nanoparticles from bergenia ligulata (whole plant). |
2022-04-03 |
2023-08-13 |
human |
| Xue Yang, Yi Fang, Jianbo Hou, Xuejiao Wang, Jiayi Li, Siyu Li, Xiaoyan Zheng, Yan Liu, Zhigang Zhan. The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis. Chemosphere. 2022-04-03. PMID:35367492. |
furthermore, dlm stimulation induced apoptosis in quail heart by decreasing the protein expressions of b-cell lymphoma-extra large and b-cell lymphoma gene 2 (bcl-2), as well as increasing p53, caspase 3, and bcl-2-associated x protein levels. |
2022-04-03 |
2023-08-13 |
Not clear |
| Vishal Kumar Gupta, Ajay Kuma. Targeting lysophosphatidic acid receptor with Ki16425 impedes T cell lymphoma progression through apoptosis induction, glycolysis inhibition, and activation of antitumor immune response. Apoptosis : an international journal on programmed cell death. 2022-04-02. PMID:35366141. |
the administration of ki16425 triggered apoptosis by down-regulating the expression of bcl2 and up-regulating p53, bax, cleaved caspase-3, and cyt c expression. |
2022-04-02 |
2023-08-13 |
Not clear |
| Pedro E Lázaro-Mixteco, José M González-Coronel, Laura Hernández-Padilla, Lorena Martínez-Alcantar, Enrique Martínez-Carranza, Jesús Salvador López-Bucio, Ángel A Guevara-García, Jesús Campos-Garcí. Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma. Frontiers in oncology. vol 12. 2022-04-01. PMID:35359411. |
bioinformatics confirmed the impact of cdps in the differential expression of genes from signal transduction pathways such as pi3k-akt, mtor, foxo, wnt, mapk, p53, tgf-β, notch, apoptosis, emt, and csc. |
2022-04-01 |
2023-08-13 |
human |