| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wuyang Lv, Jia Liao, Cuicui Li, Dongyang Liu, Xiaoxiao Luo, RuXue Diao, YuChen Wang, Yingyu Ji. Aquaporin 1 is renoprotective in septic acute kidney injury by attenuating inflammation, apoptosis and fibrosis through inhibition of P53 expression. Frontiers in immunology. vol 15. 2024-09-06. PMID:39238634. |
aquaporin 1 is renoprotective in septic acute kidney injury by attenuating inflammation, apoptosis and fibrosis through inhibition of p53 expression. |
2024-09-06 |
2024-09-08 |
mouse |
| Ganesh Suraj Bose, Shruti Jindal, Kiran Gautam Landage, Aarzoo Jindal, Monali Prakash Mahale, Abhijeet P Kulkarni, Smriti Mitta. SMAR1 and p53-regulated lncRNA RP11-431M3.1 enhances HIF1A translation via miR-138 in colorectal cancer cells under oxidative stress. The FEBS journal. 2024-09-06. PMID:39240540. |
smar1 inhibits cancer cell metastasis and invasion and is also known to inhibit apoptosis during low-dose stress in coordination with p53. |
2024-09-06 |
2024-09-08 |
Not clear |
| Luis Antonio Flores-López, Sergio Enríquez-Flores, Ignacio De La Mora-De La Mora, Itzhel García-Torres, Gabriel López-Velázquez, Rubí Viedma-Rodríguez, Alejandro Ávalos-Rodríguez, Alejandra Contreras-Ramos, Clara Ortega-Camarill. Pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (Review). Molecular medicine reports. vol 30. issue 5. 2024-09-02. PMID:39219257. |
pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (review). |
2024-09-02 |
2024-09-04 |
Not clear |
| Luis Antonio Flores-López, Sergio Enríquez-Flores, Ignacio De La Mora-De La Mora, Itzhel García-Torres, Gabriel López-Velázquez, Rubí Viedma-Rodríguez, Alejandro Ávalos-Rodríguez, Alejandra Contreras-Ramos, Clara Ortega-Camarill. Pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (Review). Molecular medicine reports. vol 30. issue 5. 2024-09-02. PMID:39219257. |
the most prominent changes are increases in reactive oxygen species, the loss of mitochondrial membrane potential and the activation of the intrinsic pathway of apoptosis due to p53. |
2024-09-02 |
2024-09-04 |
Not clear |
| Luis Antonio Flores-López, Sergio Enríquez-Flores, Ignacio De La Mora-De La Mora, Itzhel García-Torres, Gabriel López-Velázquez, Rubí Viedma-Rodríguez, Alejandro Ávalos-Rodríguez, Alejandra Contreras-Ramos, Clara Ortega-Camarill. Pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (Review). Molecular medicine reports. vol 30. issue 5. 2024-09-02. PMID:39219257. |
these modifications protect p53 from degradation by the proteasome and, in turn, enable it to regulate the intrinsic pathway of apoptosis through the regulation of anti‑apoptotic and pro‑apoptotic elements. |
2024-09-02 |
2024-09-04 |
Not clear |
| Abhishek Chauhan, Monika Yadav, Ritu Chauhan, Rupesh Kumar Basniwal, Vinay Mohan Pathak, Anuj Ranjan, Raj Kishor Kapardar, Rajpal Srivastav, Hardeep Singh Tuli, Seema Ramniwas, Darin Mansor Mathkor, Shafiul Haque, Arif Hussai. Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions. Oncology and therapy. 2024-09-02. PMID:39222186. |
in gastric cancer, ea regulates multiple pathways involved in cell proliferation, invasion, and apoptosis, including the p53 and pi3k-akt signaling pathways. |
2024-09-02 |
2024-09-04 |
Not clear |
| Fatemeh Ebadi Meinag, Mina Fatahi, Vahid Vahedian, Nazila Fathi Maroufi, Bashir Mosayyebi, Elham Ahmadi, Mohammad Rahmat. Modulatory effects of miRNAs in doxorubicin resistance: A mechanistic view. Functional & integrative genomics. vol 24. issue 5. 2024-09-02. PMID:39222264. |
this review aimed to present the current understanding of the mechanisms and effects of mirnas on apoptosis, p53 and pten/pi3k/akt signaling pathway related to dox resistance. |
2024-09-02 |
2024-09-04 |
Not clear |
| Bu-Ting Duan, Hao-Yu Zhang, Zi-Hao Song, Xiao-Yi Han, Kai-Ling Cui, Tong Xu, Yu Zhang, Yong-Juan Zhao, Xuan Lei, Fan Tan, Lu-Lu Guo, Hui-Lin Yang, Li Zhang, Rui Bai, Xiao-Ling Lv, Ming-Xue Zhen. EtROP38 suppresses apoptosis of host cells infected with Eimeria tenella by inhibition of the p38MAPK pathway. Veterinary parasitology. vol 331. 2024-09-01. PMID:39217762. |
the results showed that the addition of etrop38 and/or knockdown of the host cells p38 gene reduced the apoptosis rate of cecal epithelial cells (cecs), decreased the mrna expressions of p38, p53, c-myc, c-fos, and c-jun and increased the expression of p65, decreased the protein expressions of c-myc, c-fos, and c-jun, decreased the p38 protein phosphorylation level, and increased the p65 protein phosphorylation level in cecs. |
2024-09-01 |
2024-09-04 |
Not clear |
| Hina Qayoom, Manzoor A Mi. Mutant P53 modulation by cryptolepine through cell cycle arrest and apoptosis in triple negative breast cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 179. 2024-08-31. PMID:39216450. |
mutant p53 modulation by cryptolepine through cell cycle arrest and apoptosis in triple negative breast cancer. |
2024-08-31 |
2024-09-04 |
Not clear |
| Vahid Pourbarkhordar, Sohrab Rahmani, Ali Roohbakhsh, A Wallace Hayes, Gholamreza Karim. Melatonin effect on breast and ovarian cancers by targeting the PI3K/Akt/mTOR pathway. IUBMB life. 2024-08-30. PMID:39212097. |
b: apoptosis induction by decreasing mdm2 expression, a downstream target of akt, and mtor, which leads to bad activation in addition to bcl-xl and p53 inhibition. |
2024-08-30 |
2024-09-04 |
Not clear |
| Sujata Patha. Induction of Apoptotic Signaling Pathways by 3' methyl ATP in Different Malignant Cells: in vitro Study. Asian Pacific journal of cancer prevention : APJCP. vol 25. issue 8. 2024-08-29. PMID:39205572. |
furthermore, an upregulation of p53 and apoptosis-inducing factor (aif) was observed in hep2 cells (p<0.05) whereas, an upregulation of p53 was observed while no change was seen on the level of apoptosis inducing factor (aif) was observed in siha cells. |
2024-08-29 |
2024-09-04 |
Not clear |
| Roba Abukwaik, Elias Vera-Siguenza, Daniel Tennant, Fabian Spil. p53 Orchestrates Cancer Metabolism: Unveiling Strategies to Reverse the Warburg Effect. Bulletin of mathematical biology. vol 86. issue 10. 2024-08-29. PMID:39207627. |
additionally, our findings reveal the dynamic capability of elevated p53 activation to fully reverse the warburg effect, highlighting the significance of its activity levels not just in triggering apoptosis (programmed cell death) post-chemotherapy but also in modifying the metabolic pathways implicated in treatment resistance. |
2024-08-29 |
2024-09-04 |
Not clear |
| Shamim Nosrati, Hossein Javid, Hamed Amiri, Niloufar Jafari, Seyed Isaac Hashem. Investigating the anticancer effects of chitosan-NLC-folate nanohybrid loaded with auraptene on A2780 ovarian cancer cells. Naunyn-Schmiedeberg's archives of pharmacology. 2024-08-28. PMID:39196393. |
in vitro trials suggested that auraptene nanoparticles trigger apoptosis in a2780 cells in a dose-responsive manner by promoting the expression of pro-apoptotic genes (bax and p53), while suppressing the expression of the anti-apoptotic gene (bcl-2). |
2024-08-28 |
2024-08-30 |
human |
| Aimin Wu, Chungang Zha. Astilbin Induces Apoptosis in Oral Squamous Cell Carcinoma through p53 Reactivation and Mdm-2 Inhibition. Doklady. Biochemistry and biophysics. 2024-08-28. PMID:39196525. |
astilbin induces apoptosis in oral squamous cell carcinoma through p53 reactivation and mdm-2 inhibition. |
2024-08-28 |
2024-08-30 |
Not clear |
| Yanhua Zhu, Mei Xiao, Ruihuan Zhao, Xuefei Yang, Kun Wu, Xiao Liu, Xi Chen, Lei Guo, Jiezhen Liu, Xu Chen, Na Liu, Yuefeng He, Yanliang Zhan. Arsenic-induced downregulation of BRWD3 suppresses proliferation and induces apoptosis in lung adenocarcinoma cells through the p53 and p65 pathways. Human & experimental toxicology. vol 43. 2024-08-27. PMID:39190898. |
arsenic-induced downregulation of brwd3 suppresses proliferation and induces apoptosis in lung adenocarcinoma cells through the p53 and p65 pathways. |
2024-08-27 |
2024-08-30 |
Not clear |
| RETRACTION: FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells. Journal of cellular biochemistry. 2024-08-27. PMID:39189382. |
retraction: fv-429 induced apoptosis through ros-mediated erk2 nuclear translocation and p53 activation in gastric cancer cells. |
2024-08-27 |
2024-08-30 |
Not clear |
| Jingjing Li, Laia Jordana, Haytham Mehsen, Xinyue Wang, Vincent Archambaul. Nuclear reassembly defects after mitosis trigger apoptotic and p53-dependent safeguard mechanisms in Drosophila. PLoS biology. vol 22. issue 8. 2024-08-26. PMID:39186808. |
blocking p53 does not prevent apoptosis but enhances defects due to the loss of a cell cycle checkpoint. |
2024-08-26 |
2024-08-30 |
drosophila_melanogaster |
| Haohao Wang, Qingjie Chen, Qinghua Liu, Changjiang Lu. Master regulator: p53's pivotal role in steering NK-cell tumor patrol. Frontiers in immunology. vol 15. 2024-08-26. PMID:39185404. |
the p53 protein, encoded by tp53, is a tumor suppressor that plays a critical role in regulating apoptosis, cell cycle regulation, and angiogenesis in tumor cells via controlling various downstream signals. |
2024-08-26 |
2024-08-28 |
Not clear |
| Haohao Wang, Qingjie Chen, Qinghua Liu, Changjiang Lu. Master regulator: p53's pivotal role in steering NK-cell tumor patrol. Frontiers in immunology. vol 15. 2024-08-26. PMID:39185404. |
additionally, p53 influences nk cell cytotoxicity by promoting apoptosis, autophagy, and ferroptosis in different tumor cells. |
2024-08-26 |
2024-08-28 |
Not clear |
| Tian Zhu, Chunxia Yao, Shuang Hong, Weiguo Song, Norlaila Mohd Zanuri, Weiwei Lv, Qichen Jian. Multi-omics reveal toxicity mechanisms underpinning nanoplastic in redclaw crayfish (Cherax quadricarinatus). The Science of the total environment. 2024-08-22. PMID:39173758. |
transcriptomic analyses revealed that nps influenced apoptosis, drug metabolism-cytochrome p450, and p53 signaling pathways. |
2024-08-22 |
2024-08-25 |
Not clear |