| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gang Xu, Huaifu Wang, Gang He, Dezhong Che. [Expressions of p53 and p21 in nasal NK/T-cell lymphoma and their relationship with the proliferation and apoptosis of cells]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 23. issue 2. 2011-06-30. PMID:19452712. |
[expressions of p53 and p21 in nasal nk/t-cell lymphoma and their relationship with the proliferation and apoptosis of cells]. |
2011-06-30 |
2023-08-12 |
Not clear |
| Gang Xu, Huaifu Wang, Gang He, Dezhong Che. [Expressions of p53 and p21 in nasal NK/T-cell lymphoma and their relationship with the proliferation and apoptosis of cells]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 23. issue 2. 2011-06-30. PMID:19452712. |
to investigate the significance of expressions of p53 and p21 in nasal nk/t-cell lymphoma (nktl) and their relationship with cell proliferation and apoptosis. |
2011-06-30 |
2023-08-12 |
Not clear |
| Ni Sima, Weiguo Lü, Xing Xi. Early proteins E6 and E7 of human papillomavirus may attenuate ischemia-reperfusion injury. Medical hypotheses. vol 76. issue 4. 2011-06-30. PMID:21277688. |
early proteins e6 and e7 of hpv both are oncoproteins for they disable specific tumor suppressor proteins, p53 and prb, and disturb apoptosis against carcinogenesis. |
2011-06-30 |
2023-08-12 |
human |
| Ni Sima, Weiguo Lü, Xing Xi. Early proteins E6 and E7 of human papillomavirus may attenuate ischemia-reperfusion injury. Medical hypotheses. vol 76. issue 4. 2011-06-30. PMID:21277688. |
both p53 and prb play an important role in regulating apoptosis and preventing cell immortalization, but they also mediate ischemia/reperfusion-associated apoptosis and give rise to ischemia-reperfusion injury (iri). |
2011-06-30 |
2023-08-12 |
human |
| Ni Sima, Weiguo Lü, Xing Xi. Early proteins E6 and E7 of human papillomavirus may attenuate ischemia-reperfusion injury. Medical hypotheses. vol 76. issue 4. 2011-06-30. PMID:21277688. |
both small-molecule chemical inhibitor and sirna against p53 block p53-dependent apoptosis and protect organ function from iri. |
2011-06-30 |
2023-08-12 |
human |
| Ni Sima, Weiguo Lü, Xing Xi. Early proteins E6 and E7 of human papillomavirus may attenuate ischemia-reperfusion injury. Medical hypotheses. vol 76. issue 4. 2011-06-30. PMID:21277688. |
based on these studies, we propose a novel hypothesis that early proteins e6 and e7 of hpv attenuate ischemia-reperfusion injury by inhibiting apoptosis and inactivating p53 and prb. |
2011-06-30 |
2023-08-12 |
human |
| Bing Hu, Ke-Ping Shen, Hong-Mei An, Yang Wu, Qin D. Aqueous extract of Curcuma aromatica induces apoptosis and G2/M arrest in human colon carcinoma LS-174-T cells independent of p53. Cancer biotherapy & radiopharmaceuticals. vol 26. issue 1. 2011-06-30. PMID:21348775. |
aqueous extract of curcuma aromatica induces apoptosis and g2/m arrest in human colon carcinoma ls-174-t cells independent of p53. |
2011-06-30 |
2023-08-12 |
human |
| Bing Hu, Ke-Ping Shen, Hong-Mei An, Yang Wu, Qin D. Aqueous extract of Curcuma aromatica induces apoptosis and G2/M arrest in human colon carcinoma LS-174-T cells independent of p53. Cancer biotherapy & radiopharmaceuticals. vol 26. issue 1. 2011-06-30. PMID:21348775. |
expression of p53 was unchanged after aeca treatment; specific silence of p53 did not influence aeca-induced apoptosis and g2/m phase arrest. |
2011-06-30 |
2023-08-12 |
human |
| Bing Hu, Ke-Ping Shen, Hong-Mei An, Yang Wu, Qin D. Aqueous extract of Curcuma aromatica induces apoptosis and G2/M arrest in human colon carcinoma LS-174-T cells independent of p53. Cancer biotherapy & radiopharmaceuticals. vol 26. issue 1. 2011-06-30. PMID:21348775. |
this study suggests that aeca might be effective as an antiproliferative herb for colon carcinoma, the antitumor activity of aeca may involve both extrinsic and intrinsic apoptosis, and aeca induces g2/m phase arrest via downregulation of cyclin b1 and cdk1 and without the participation of p53. |
2011-06-30 |
2023-08-12 |
human |
| Zhongfeng Wang, Baojie L. Mdm2 links genotoxic stress and metabolism to p53. Protein & cell. vol 1. issue 12. 2011-06-29. PMID:21213101. |
activated p53 inhibits cell proliferation, induces apoptosis or senescence, and maintains genome integrity. |
2011-06-29 |
2023-08-12 |
mouse |
| Yayun Liang, Cynthia Besch-Williford, Indira Benakanakere, Philip E Thorpe, Salman M Hyde. Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors. Breast cancer research and treatment. vol 125. issue 2. 2011-06-28. PMID:20349129. |
we examined the therapeutic effects, singly, or in combination, of p53 reactivation and induction of massive apoptosis (prima-1), which reactivates mtp53 and induces tumor cell apoptosis, and 2ag4, a monoclonal antibody that disrupts tumor vasculature by targeting ap on the surface of tumor endothelial cells and causes antibody-dependent destruction of tumor blood vessels, leading to ischemia and tumor cell death. |
2011-06-28 |
2023-08-12 |
mouse |
| Xiaosong Wu, Jumei Shi, Yi Wu, Yi Tao, Jun Hou, Xiuqin Meng, Xiaojing Hu, Ying Han, Wei Jiang, Siyuan Tang, Maurizio Zangari, Guido Tricot, Fenghuang Zha. Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2. Cancer biology & therapy. vol 10. issue 11. 2011-06-28. PMID:20953137. |
in this study, the molecular mechanisms of ato-induced myeloma apoptosis were explored on four myeloma cell lines of wild type or mutant p53 status and also on six primary myeloma cells. |
2011-06-28 |
2023-08-12 |
Not clear |
| Xiaosong Wu, Jumei Shi, Yi Wu, Yi Tao, Jun Hou, Xiuqin Meng, Xiaojing Hu, Ying Han, Wei Jiang, Siyuan Tang, Maurizio Zangari, Guido Tricot, Fenghuang Zha. Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2. Cancer biology & therapy. vol 10. issue 11. 2011-06-28. PMID:20953137. |
together, our data suggest that ato induces apoptosis in mm through either extrinsic or intrinsic signaling pathway, depending on the p53 genetic background. |
2011-06-28 |
2023-08-12 |
Not clear |
| Mohamed M Abouheif, Tomoyuki Nakasa, Hayatoshi Shibuya, Takuya Niimoto, Wirat Kongcharoensombat, Mitsuo Och. Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro. Rheumatology (Oxford, England). vol 49. issue 11. 2011-06-27. PMID:20675358. |
mirna (mir)-34a is induced by p53, subsequently leading to cell apoptosis, which is one of the major factors in the pathogenesis of oa. |
2011-06-27 |
2023-08-12 |
rat |
| Cristine Alves da Costa, Frédéric Checle. Apoptosis in Parkinson's disease: is p53 the missing link between genetic and sporadic Parkinsonism? Cellular signalling. vol 23. issue 6. 2011-06-27. PMID:20969953. |
apoptosis in parkinson's disease: is p53 the missing link between genetic and sporadic parkinsonism? |
2011-06-27 |
2023-08-12 |
Not clear |
| Helena R C Segreto, Celina T F Oshima, Marcello F Franco, Maria Regina R Silva, Mizue I Egami, Vicente P C Teixeira, Roberto A Segret. Phosphorylation and cytoplasmic localization of MAPK p38 during apoptosis signaling in bone marrow granulocytes of mice irradiated in vivo and the role of amifostine in reducing these effects. Acta histochemica. vol 113. issue 3. 2011-06-24. PMID:20074782. |
we studied p38 phosphorylation and its intracellular localization during p53 and puma (a p53 upregulated modulator of apoptosis) apoptotic signaling pathway in bone marrow granulocytes in mice irradiated in vivo and the role of the radioprotector amifostine in ameliorating these responses. |
2011-06-24 |
2023-08-12 |
mouse |
| V G Bezlepkin, E N Kirillova, M L Zakharova, O S Pavlova, M G Lomaeva, L A Fomenko, V N Antipova, A I Gazie. [Delayed and transgenerational molecular and genetic effects of prolonged influence of ionizing radiation in nuclear plant workers]. Radiatsionnaia biologiia, radioecologiia. vol 51. issue 1. 2011-06-24. PMID:21520613. |
the concentration changes of tgf-beta1, apoptosis proteins (p53, tpa-cyk, sapo-1/fas), and the adhesion molecule scd27 in the case of cardiovascular diseases in the serum of both irradiated and non-irradiated "mayak" pa employers point to the information value of these immune response characteristics as specific biomarkers of cardiac disorders. |
2011-06-24 |
2023-08-12 |
human |
| Qiuyan Li. Triptolide and its expanding multiple pharmacological functions. International immunopharmacology. vol 11. issue 3. 2011-06-23. PMID:21255694. |
triptolide cannot only induce tumor cell apoptosis directly, but can also enhance apoptosis induced by cytotoxic agents such as tnf-α, trail and chemotherapeutic agents regardless of p53 phenotype by inhibiting nfκb activation. |
2011-06-23 |
2023-08-12 |
Not clear |
| Bi-Xia Tang, Xin You, Li-Dan Zhao, Yang Li, Xuan Zhang, Fu-Lin Tang, De-Nian Ba, Wei H. p53 in fibroblast-like synoviocytes can regulate T helper cell functions in patients with active rheumatoid arthritis. Chinese medical journal. vol 124. issue 3. 2011-06-23. PMID:21362334. |
p53 is a tumor suppressor and plays a key role in regulating cell hyperplasia, repairing dna and inducing apoptosis. |
2011-06-23 |
2023-08-12 |
Not clear |
| M Zhong, D H Carney, H Jo, B D Boyan, Z Schwart. Inorganic phosphate induces mammalian growth plate chondrocyte apoptosis in a mitochondrial pathway involving nitric oxide and JNK MAP kinase. Calcified tissue international. vol 88. issue 2. 2011-06-22. PMID:21104071. |
snog also upregulated p53 expression, the bax/bcl-2 expression ratio, and cytochrome c release from mitochondria, as well as caspase-3 activity, indicating that no induces apoptosis via a mitochondrial pathway. |
2011-06-22 |
2023-08-12 |
mouse |