| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Yang, Jing Wang, Hong-Mei Jing, Xiao-Yan K. [Effect of magnetic nanoparticle of Fe3O4 combined with daunorubicin on lymphoma cell line Raji]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 2. 2012-01-12. PMID:21518493. |
the raji cells were cultured with fe3o4-magnetic nanoparticle and daunorubicin polymerized by means of mechanical absorption, the cell viability was detected by mtt and trypan-blue exclusion; the apoptosis was detected by flow cytometry, the expressions of p53 and p65 are measured by western blot. |
2012-01-12 |
2023-08-12 |
Not clear |
| Ping Yang, Jing Wang, Hong-Mei Jing, Xiao-Yan K. [Effect of magnetic nanoparticle of Fe3O4 combined with daunorubicin on lymphoma cell line Raji]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 2. 2012-01-12. PMID:21518493. |
it is concluded that the combination treatment of mnp-fe3o4 and daunorubicin efficiently inhibits growth and induces apoptosis in raji cell line, while the activation of p53 and down-regulation of nf-κb may play important roles. |
2012-01-12 |
2023-08-12 |
Not clear |
| Vivek Sharma, Deobrat Dixit, Sadashib Ghosh, Ellora Se. COX-2 regulates the proliferation of glioma stem like cells. Neurochemistry international. vol 59. issue 5. 2012-01-12. PMID:21763744. |
despite upregulating p53 expression il-1β had no effect on cell cycle progression, apoptosis or self renewal capacity of cscs. |
2012-01-12 |
2023-08-12 |
Not clear |
| Vincenza Ortenzi, Roberta Meschini, Andrea Berni, Pierluigi Mancinelli, Fabrizio Palitt. Study on X-ray-induced apoptosis and chromosomal damage in G2 human lymphocytes in the presence of pifithrin-α, an inhibitor of p53. Mutation research. vol 726. issue 1. 2012-01-12. PMID:21889606. |
study on x-ray-induced apoptosis and chromosomal damage in g2 human lymphocytes in the presence of pifithrin-α, an inhibitor of p53. |
2012-01-12 |
2023-08-12 |
human |
| Vincenza Ortenzi, Roberta Meschini, Andrea Berni, Pierluigi Mancinelli, Fabrizio Palitt. Study on X-ray-induced apoptosis and chromosomal damage in G2 human lymphocytes in the presence of pifithrin-α, an inhibitor of p53. Mutation research. vol 726. issue 1. 2012-01-12. PMID:21889606. |
at early sampling times after x-ray exposure the following parameters were analysed: cellular proliferation, apoptosis, chromosomal aberrations and p53 expression. |
2012-01-12 |
2023-08-12 |
human |
| Rachael Rutkowski, Robin Dickinson, Graeme Stewart, Ashley Craig, Marianne Schimpl, Stephen M Keyse, Anton Gartne. Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling. PLoS genetics. vol 7. issue 8. 2012-01-12. PMID:21901106. |
the sole caenorhabditis elegans p53 family member cep-1 is required for apoptosis induction in meiotic, late-stage pachytene germ cells in response to dna damage and meiotic recombination failure. |
2012-01-12 |
2023-08-12 |
caenorhabditis_elegans |
| Rachael Rutkowski, Robin Dickinson, Graeme Stewart, Ashley Craig, Marianne Schimpl, Stephen M Keyse, Anton Gartne. Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling. PLoS genetics. vol 7. issue 8. 2012-01-12. PMID:21901106. |
since apoptosis is also restricted to pachytene stage cells in mammalian germlines, analogous mechanisms regulating p53 family members are likely to be conserved throughout evolution. |
2012-01-12 |
2023-08-12 |
caenorhabditis_elegans |
| Nam Hee Kim, Hyun Sil Kim, Xiao-Yan Li, Inhan Lee, Hyung-Seok Choi, Shi Eun Kang, So Young Cha, Joo Kyung Ryu, Dojun Yoon, Eric R Fearon, R Grant Rowe, Sanghyuk Lee, Christopher A Maher, Stephen J Weiss, Jong In Yoo. A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. The Journal of cell biology. vol 195. issue 3. 2012-01-12. PMID:22024162. |
although p53 activity can impact cell cycle regulation, apoptosis, and dna repair pathways, the emt and invasion programs initiated by p53 loss of function or mutation are completely dependent on snail1 expression. |
2012-01-12 |
2023-08-12 |
Not clear |
| Alireza Shoae-Hassani, Shiva Sharif, Javad Verd. The neurosteroid dehydroepiandrosterone could improve somatic cell reprogramming. Cell biology international. vol 35. issue 10. 2012-01-11. PMID:21355850. |
apoptosis via the p53 pathway serves as a major barrier in nuclear somatic cell reprogramming during ipsc generation. |
2012-01-11 |
2023-08-12 |
Not clear |
| Alireza Shoae-Hassani, Shiva Sharif, Javad Verd. The neurosteroid dehydroepiandrosterone could improve somatic cell reprogramming. Cell biology international. vol 35. issue 10. 2012-01-11. PMID:21355850. |
dhea (dehydroepiandrosterone) is an abundant steroid that is produced at high levels in the adrenal cells, and withdrawal of dhea increases the levels of p53 in the epithelial and stromal cells, resulting in increased levels of apoptotic cells; meanwhile, dhea decreases cellular apoptosis. |
2012-01-11 |
2023-08-12 |
Not clear |
| Alireza Shoae-Hassani, Shiva Sharif, Javad Verd. The neurosteroid dehydroepiandrosterone could improve somatic cell reprogramming. Cell biology international. vol 35. issue 10. 2012-01-11. PMID:21355850. |
dhea could improve the efficacy of reprogramming yield due to a decrease in apoptosis via the p53 pathway and an increase in cell viability. |
2012-01-11 |
2023-08-12 |
Not clear |
| Cristina P R Xavier, Cristovao F Lima, Mikkel Rohde, Cristina Pereira-Wilso. Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. Cancer chemotherapy and pharmacology. vol 68. issue 6. 2012-01-11. PMID:21479885. |
quercetin enhances 5-fluorouracil-induced apoptosis in msi colorectal cancer cells through p53 modulation. |
2012-01-11 |
2023-08-12 |
Not clear |
| Christophe Stenger, Thomas Naves, Mireille Verdier, Marie-Helene Ratinau. The cell death response to the ROS inducer, cobalt chloride, in neuroblastoma cell lines according to p53 status. International journal of oncology. vol 39. issue 3. 2012-01-11. PMID:21687937. |
finally, cocl2 induced time-dependent canonical p53 mitochondrial apoptosis in the wt p53 cell line, and caspase-independent cell death in cells with a mutated or ko p53. |
2012-01-11 |
2023-08-12 |
Not clear |
| Huang-Yao Tu, A-Mei Huang, Chi-Huang Teng, Tzyh-Chyuan Hour, Shyh-Chyun Yang, Yeong-Shiau Pu, Chun-Nan Li. Anthraquinone derivatives induce G2/M cell cycle arrest and apoptosis in NTUB1 cells. Bioorganic & medicinal chemistry. vol 19. issue 18. 2012-01-10. PMID:21852140. |
biological results suggested that the induction of g2/m arrest, apoptosis, and cell death by 9 may associate with increased expression of p21 and cyclin b1, elevation of bax and p53 levels, and generation of ros in the cell. |
2012-01-10 |
2023-08-12 |
human |
| Ulrika Nyman, Naveen Reddy Muppani, Boris Zhivotovsky, Bertrand Josep. Hsp72 mediates TAp73α anti-apoptotic effects in small cell lung carcinoma cells. Journal of cellular and molecular medicine. vol 15. issue 8. 2012-01-09. PMID:20807285. |
the transcription factor p73, a member of the p53 family of proteins, is involved in the regulation of cell cycle progression and apoptosis. |
2012-01-09 |
2023-08-12 |
Not clear |
| Joshua M Spin, Mark Hsu, Junya Azuma, Maureen M Tedesco, Alicia Deng, Justin S Dyer, Lars Maegdefessel, Ronald L Dalman, Philip S Tsa. Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm. Physiological genomics. vol 43. issue 17. 2012-01-09. PMID:21712436. |
ontologic analysis revealed widespread upregulation of inflammatory, immune, and matrix remodeling genes with ang ii treatment, among other pathways such as apoptosis, cell cycling, angiogenesis, and p53 signaling. |
2012-01-09 |
2023-08-12 |
mouse |
| Xiaobo Yan, Jie Feng, Zhaoming Ye, Xudong Miao, Weixu Li, Disheng Yan. p53 siRNA inhibits apoptosis of U2OS cells treated with azurin. Molecular medicine reports. vol 4. issue 6. 2012-01-09. PMID:21822538. |
p53 sirna inhibits apoptosis of u2os cells treated with azurin. |
2012-01-09 |
2023-08-12 |
human |
| Xiaobo Yan, Jie Feng, Zhaoming Ye, Xudong Miao, Weixu Li, Disheng Yan. p53 siRNA inhibits apoptosis of U2OS cells treated with azurin. Molecular medicine reports. vol 4. issue 6. 2012-01-09. PMID:21822538. |
cells treated with p53 sirna and azurin showed more viable cells, a lower apoptosis rate, lower caspase-3 activity, and up-regulation of bcl-2, downregulation of bax compared to cells treated with negative sirna and azurin. |
2012-01-09 |
2023-08-12 |
human |
| Xiaobo Yan, Jie Feng, Zhaoming Ye, Xudong Miao, Weixu Li, Disheng Yan. p53 siRNA inhibits apoptosis of U2OS cells treated with azurin. Molecular medicine reports. vol 4. issue 6. 2012-01-09. PMID:21822538. |
these results suggested that p53 sirna was capable of inhibi-ting the apoptosis induced by azurin 2 days after treatment with p53 sirna and azurin. |
2012-01-09 |
2023-08-12 |
human |
| Xiaobo Yan, Jie Feng, Zhaoming Ye, Xudong Miao, Weixu Li, Disheng Yan. p53 siRNA inhibits apoptosis of U2OS cells treated with azurin. Molecular medicine reports. vol 4. issue 6. 2012-01-09. PMID:21822538. |
azurin may induce apoptosis through combination with p53. |
2012-01-09 |
2023-08-12 |
human |