| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ilknur Sur, Mine Altunbek, Mehmet Kahraman, Mustafa Culh. The influence of the surface chemistry of silver nanoparticles on cell death. Nanotechnology. vol 23. issue 37. 2013-01-16. PMID:22922335. |
compared to the o-agnps, the l-agnps triggered more cellular dna damage, which led to up-regulation of p53 gene inducing apoptosis in a549 cells compared to hdf cells. |
2013-01-16 |
2023-08-12 |
human |
| Lihua Min, Yuan Ji, Latifa Bakiri, Zhixin Qiu, Jin Cen, Xiaotao Chen, Lingli Chen, Harald Scheuch, Hai Zheng, Lunxiu Qin, Kurt Zatloukal, Lijian Hui, Erwin F Wagne. Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin. Nature cell biology. vol 14. issue 11. 2013-01-16. PMID:23041974. |
here we show using genetic mouse models specific for liver cancer initiation, that survival of initiated cancer cells is controlled by c-jun, independently of p53, through suppressing c-fos-mediated apoptosis. |
2013-01-16 |
2023-08-12 |
mouse |
| J F N Pinto Rodrigues, C T Fujiyama Oshima, A P Ribeiro Paiotti, M Franco, S S Miki Ihara, D A Ribeir. Expression of apoptosis regulatory proteins p53, bcl-2 and bax in recurrent aphthous ulceration. Journal of the European Academy of Dermatology and Venereology : JEADV. vol 26. issue 10. 2013-01-15. PMID:22092434. |
expression of apoptosis regulatory proteins p53, bcl-2 and bax in recurrent aphthous ulceration. |
2013-01-15 |
2023-08-12 |
Not clear |
| Lijuan Liu, Xiaobei Chen, Shuixiang Xie, Chuanjie Zhang, Zhenpeng Qiu, Fan Zh. Variant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation. Hepatology (Baltimore, Md.). vol 56. issue 5. 2013-01-15. PMID:22576474. |
variant 1 of kiaa0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation. |
2013-01-15 |
2023-08-12 |
human |
| Lijuan Liu, Xiaobei Chen, Shuixiang Xie, Chuanjie Zhang, Zhenpeng Qiu, Fan Zh. Variant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation. Hepatology (Baltimore, Md.). vol 56. issue 5. 2013-01-15. PMID:22576474. |
additionally, kiaa0101 tv1 prevented cells from apoptosis caused by adr through suppressing the acetylation of p53 at lys382. |
2013-01-15 |
2023-08-12 |
human |
| Lijuan Liu, Xiaobei Chen, Shuixiang Xie, Chuanjie Zhang, Zhenpeng Qiu, Fan Zh. Variant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation. Hepatology (Baltimore, Md.). vol 56. issue 5. 2013-01-15. PMID:22576474. |
taken together, our data suggest that kiaa0101 tv1 played an important role in the late stage of metastatic hcc and prevented apoptosis after chemotherapeutic drug treatment through inhibiting the transcriptional activity of the p53 gene. |
2013-01-15 |
2023-08-12 |
human |
| S Lee, J-Y Kim, Y-J Kim, K-O Seok, J-H Kim, Y-J Chang, H-Y Kang, J-H Par. Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses. Cell death and differentiation. vol 19. issue 10. 2013-01-14. PMID:22522597. |
p53 is a key regulator of cell growth and death by controlling cell cycle progression and apoptosis under conditions of stress such as dna damage or oncogenic stimulation. |
2013-01-14 |
2023-08-12 |
human |
| A Küçük, M Yucel, N Erkasap, M Tosun, T Koken, M Ozkurt, S Erkasa. The effects of PDE5 inhibitory drugs on renal ischemia/reperfusion injury in rats. Molecular biology reports. vol 39. issue 10. 2013-01-14. PMID:22736111. |
the aim of the present study was to evaluate the effects of phosphodiesterase type 5 (pde5) inhibitory drugs, tadalafil and sildenafil, on inducible nos (inos), endothelial nos (enos) and p53 genes expressions and apoptosis in ischemia/reperfusion (i/r) induced oxidative injury in rat renal tissue. |
2013-01-14 |
2023-08-12 |
rat |
| F Esposito, M Tornincasa, A Federico, G Chiappetta, G M Pierantoni, A Fusc. High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria. Cell death & disease. vol 3. 2013-01-14. PMID:22932725. |
here, we first confirm the localization of the hmga1 proteins in the cytoplasm of cancer cells, and then we report a novel mechanism through which hmga1 inhibits p53-mitochondrial apoptosis by counteracting the binding of p53 to the anti-apoptotic factor bcl-2. |
2013-01-14 |
2023-08-12 |
Not clear |
| F Esposito, M Tornincasa, A Federico, G Chiappetta, G M Pierantoni, A Fusc. High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria. Cell death & disease. vol 3. 2013-01-14. PMID:22932725. |
this interaction occurs at mitochondria interfering with the ability of p53 protein to bind bcl-2, thus counteracting p53-mediated mitochondrial apoptosis. |
2013-01-14 |
2023-08-12 |
Not clear |
| G Nayak, G M Coope. p53 is a major component of the transcriptional and apoptotic program regulated by PI 3-kinase/Akt/GSK3 signaling. Cell death & disease. vol 3. 2013-01-14. PMID:23059819. |
expression of dominant-negative p53 conferred partial resistance to apoptosis induced by inhibition of pi 3-kinase. |
2013-01-14 |
2023-08-12 |
Not clear |
| A Goel, R Chhabra, S Ahmad, A K Prasad, V S Parmar, B Ghosh, N Sain. DAMTC regulates cytoskeletal reorganization and cell motility in human lung adenocarcinoma cell line: an integrated proteomics and transcriptomics approach. Cell death & disease. vol 3. 2013-01-14. PMID:23059821. |
it induces apoptosis through mitochondrial pathway by modulating nf-κb, mitogen-activated protein kinase (mapk) and p53 pathways. |
2013-01-14 |
2023-08-12 |
human |
| Hoe-Jin Kang, Young-Joo Jan. Selective apoptotic effect of Zelkova serrata twig extract on mouth epidermoid carcinoma through p53 activation. International journal of oral science. vol 4. issue 2. 2013-01-10. PMID:22498930. |
apoptosis was not remarkably induced by treatment with the extract in either lower gingival squamous or tongue mucoepidermoid carcinoma cells, both of which contain abnormalities of p53. |
2013-01-10 |
2023-08-12 |
human |
| Sanchita P Ghosh, Shilpa Kulkarni, Michael W Perkins, Kevin Hieber, Roli L Pessu, Kristen Gambles, Manoj Maniar, Tzu-Cheg Kao, Thomas M Seed, K Sree Kuma. Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice. Journal of radiation research. vol 53. issue 4. 2013-01-10. PMID:22843617. |
in our previous study, we reported that ex-rad, a small-molecule radioprotectant, enhances survival of mice exposed to gamma radiation, and prevents radiation-induced apoptosis as measured by the inhibition of radiation-induced protein 53 (p53) expression in cultured cells. |
2013-01-10 |
2023-08-12 |
mouse |
| Bin Yue, Yu-Sheng Zhang, Hui-Min Xu, Cui-Rong Zhao, Yuan-Yuan Li, Yi-Zhuo Qin, Rui-Qi Wang, Di Sun, Yi Yuan, Hong-Xiang Lou, Xian-Jun Q. Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human hepatocellular carcinoma growth through induction of apoptosis in p53-dependent way. Cancer letters. vol 328. issue 1. 2013-01-10. PMID:22995069. |
riccardin d-26 activated p53 expression and induced cancer cells to apoptosis through the p53-mediated transcription-dependent and -independent pathway. |
2013-01-10 |
2023-08-12 |
mouse |
| Dae-Hee Lee, Tae Hwa Lee, Chang Hwa Jung, Young-Ho Ki. Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells. Cellular signalling. vol 24. issue 11. 2013-01-09. PMID:22846543. |
wogonin induces apoptosis by activating the ampk and p53 signaling pathways in human glioblastoma cells. |
2013-01-09 |
2023-08-12 |
human |
| Dae-Hee Lee, Tae Hwa Lee, Chang Hwa Jung, Young-Ho Ki. Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells. Cellular signalling. vol 24. issue 11. 2013-01-09. PMID:22846543. |
furthermore, in gbm cells, wogonin blocked cell cycle progression at the g1 phase and induced apoptosis by inducing p53 expression and further upregulating p21 expression. |
2013-01-09 |
2023-08-12 |
human |
| E Madan, R Gogna, P Kuppusamy, M Bhatt, U Pati, A A Mahd. TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex. British journal of cancer. vol 107. issue 3. 2013-01-08. PMID:22782351. |
p53 induces cell-cycle arrest and apoptosis in cancer cells and negatively regulates glycolysis via tigar. |
2013-01-08 |
2023-08-12 |
Not clear |
| Shannon T Bailey, Hyunjin Shin, Thomas Westerling, Xiaole Shirley Liu, Myles Brow. Estrogen receptor prevents p53-dependent apoptosis in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 44. 2013-01-08. PMID:23077249. |
despite harboring wild-type p53, er+ breast cancer cells are resistant to chemotherapy-induced apoptosis in the presence of estrogen. |
2013-01-08 |
2023-08-12 |
Not clear |
| Sharon L Hyzy, Rene Olivares-Navarrete, Zvi Schwartz, Barbara D Boya. BMP2 induces osteoblast apoptosis in a maturation state and noggin-dependent manner. Journal of cellular biochemistry. vol 113. issue 10. 2013-01-07. PMID:22628200. |
apoptosis was characterized by caspase-3, bax/bcl2, p53, and dna fragmentation. |
2013-01-07 |
2023-08-12 |
human |