| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zheng Lai, Simona Moravcová, Yvan Canitrot, Lukasz P Andrzejewski, Dervla M Walshe, Stephen Re. Msl2 is a novel component of the vertebrate DNA damage response. PloS one. vol 8. issue 7. 2014-02-24. PMID:23874665. |
although it has been shown to target histone h2b at lysine 34 and p53 at lysine 351, suggesting roles in transcription regulation and apoptosis, its function in these and other processes remains poorly defined. |
2014-02-24 |
2023-08-12 |
human |
| Yang Zhao, Ji-Long Ren, Ming-Yang Wang, Sheng-Ting Zhang, Yu Liu, Min Li, Yi-Bin Cao, Hu-Yue Zu, Xiao-Cheng Chen, Chung-I Wu, Eviatar Nevo, Xue-Qun Chen, Ji-Zeng D. Codon 104 variation of p53 gene provides adaptive apoptotic responses to extreme environments in mammals of the Tibet plateau. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 51. 2014-02-24. PMID:24297887. |
the 104e p53 variant in microtus oeconomus suppresses apoptotic gene transactivation and cell apoptosis. |
2014-02-24 |
2023-08-12 |
human |
| Qianqian Li, Hongbin Zhang, Cui Tan, Weiyan Peng, Guosheng Ren, Bei Jia, Ying He, Pilong Wang, Xiangyang Zhou, Tingxiu Xian. AdHu5-apoptin induces G2/M arrest and apoptosis in p53-mutated human gastric cancer SGC-7901 cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 6. 2014-02-21. PMID:23812727. |
the apoptosis induced by adhu5-apoptin was independent of anti-apoptotic bcl-2 and bcl-xl proteins and the p53 pathway. |
2014-02-21 |
2023-08-12 |
mouse |
| Anjana K Negi, Shevali Kansal, Archana Bhatnagar, Navneet Agnihotr. Alteration in apoptosis and cell cycle by celecoxib and/or fish oil in 7,12-dimethyl benzene (α) anthracene-induced mammary carcinogenesis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 6. 2014-02-21. PMID:24057882. |
the chemopreventive effect was assessed by measurement of cell proliferation, apoptosis, and p53 in isolated mammary epithelial cells. |
2014-02-21 |
2023-08-12 |
rat |
| Anjana K Negi, Shevali Kansal, Archana Bhatnagar, Navneet Agnihotr. Alteration in apoptosis and cell cycle by celecoxib and/or fish oil in 7,12-dimethyl benzene (α) anthracene-induced mammary carcinogenesis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 6. 2014-02-21. PMID:24057882. |
pretreatment of carcinogen-treated animals with celecoxib and/or fish oil altered redox signaling with reduced c-myc, p53 expression, apoptosis, and proliferation. |
2014-02-21 |
2023-08-12 |
rat |
| Kirsten Lundgreen, Øystein Lian, Alex Scott, Lars Engebretse. Increased levels of apoptosis and p53 in partial-thickness supraspinatus tendon tears. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. vol 21. issue 7. 2014-02-20. PMID:23052118. |
increased levels of apoptosis and p53 in partial-thickness supraspinatus tendon tears. |
2014-02-20 |
2023-08-12 |
Not clear |
| M J Groves, C E Johnson, J James, A R Prescott, J Cunningham, S Haydock, C Pepper, C Fegan, L Pirrie, N J Westwood, P J Coates, I G Ganley, S Taur. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia. British journal of cancer. vol 109. issue 9. 2014-02-20. PMID:24091621. |
activation of wild-type p53 with the small molecule sirtuin inhibitor tenovin-6 (tnv-6) induces p53-dependent apoptosis in many malignant cells. |
2014-02-20 |
2023-08-12 |
Not clear |
| Sabana Khatun, Shail K Chaube, Chandra N Bhattacharyy. p53 activation and mitochondria-mediated pathway are involved during hanging death-induced neuronal cell apoptosis in dentate gyrus region of the rat brain. SpringerPlus. vol 2. 2014-02-20. PMID:24555164. |
p53 activation and mitochondria-mediated pathway are involved during hanging death-induced neuronal cell apoptosis in dentate gyrus region of the rat brain. |
2014-02-20 |
2023-08-12 |
rat |
| Jiwoon Lee, Bum-Kyu Lee, Jeffrey M Gros. Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata. Human molecular genetics. vol 22. issue 17. 2014-02-19. PMID:23669349. |
together, this regulatory network functions to repress p53 expression and thereby suppress apoptosis in the developing optic cup. |
2014-02-19 |
2023-08-12 |
xenopus_laevis |
| Nirmalya Sen, Rajni Kumari, Manika Indrajit Singh, Sanjeev Da. HDAC5, a key component in temporal regulation of p53-mediated transactivation in response to genotoxic stress. Molecular cell. vol 52. issue 3. 2014-02-18. PMID:24120667. |
concomitantly, p53 is acetylated at the k120 residue and selectively transactivates proapoptotic target genes, leading to onset of apoptosis. |
2014-02-18 |
2023-08-12 |
mouse |
| Sushil Kumar Sahu, Suchitra Mohanty, Amit Kumar, Chanakya N Kundu, Subhash C Verma, Tathagata Choudhur. Epstein-Barr virus nuclear antigen 3C interact with p73: Interplay between a viral oncoprotein and cellular tumor suppressor. Virology. vol 448. 2014-02-18. PMID:24314664. |
the p73 protein has structural and functional homology with the tumor suppressor p53, which plays an important role in cell cycle regulation, apoptosis, and dna repair. |
2014-02-18 |
2023-08-12 |
human |
| Sushil Kumar Sahu, Suchitra Mohanty, Amit Kumar, Chanakya N Kundu, Subhash C Verma, Tathagata Choudhur. Epstein-Barr virus nuclear antigen 3C interact with p73: Interplay between a viral oncoprotein and cellular tumor suppressor. Virology. vol 448. 2014-02-18. PMID:24314664. |
doxorubicin, a commonly used chemotherapeutic agent, induces apoptosis through p53 and p73 signaling such that the lowΔnp73 level promotes the p73-mediated intrinsic pathway of apoptosis. |
2014-02-18 |
2023-08-12 |
human |
| Yanchun Du, Lin Deng, Yan Li, Lu Gan, Yantang Wang, Guixiu Sh. Decreased PERP expression on peripheral blood mononuclear cells from patient with rheumatoid arthritis negatively correlates with disease activity. Clinical & developmental immunology. vol 2013. 2014-02-17. PMID:24066004. |
perp, p53 apoptosis effector related to pmp-22, is a p53-dependent apoptosis in diverse cell types and has cell type-specific roles in p53-mediated apoptosis. |
2014-02-17 |
2023-08-12 |
Not clear |
| b' Michael Jel\\xc3\\xadnek, Kamila Balu\\xc5\\xa1\\xc3\\xadkov\\xc3\\xa1, Dana Kopperov\\xc3\\xa1, Vlasta N\\xc4\\x95mcov\\xc3\\xa1-F\\xc3\\xbcrstov\\xc3\\xa1, Jan \\xc5\\xa0r\\xc3\\xa1mek, Julie Fidlerov\\xc3\\xa1, Ilaria Zanardi, Iwao Ojima, Jan Kov\\xc3\\xa1\\xc5\\x9. Caspase-2 is involved in cell death induction by taxanes in breast cancer cells. Cancer cell international. vol 13. issue 1. 2014-02-13. PMID:23672670.' |
we studied the role of caspase-2 in apoptosis induction by taxanes (paclitaxel, novel taxane sb-t-1216) in breast cancer cells using sk-br-3 (nonfunctional p53, functional caspase-3) and mcf-7 (functional p53, nonfunctional caspase-3) cell lines. |
2014-02-13 |
2023-08-12 |
Not clear |
| Mahdieh Sadat Taghavi, Azim Akbarzadeh, Reza Mahdian, Kayhan Azadmanesh, Gholamreza Javad. Cisplatin downregulates BCL2L12, a novel apoptosis-related gene, in glioblastoma cells. In vitro cellular & developmental biology. Animal. vol 49. issue 6. 2014-02-13. PMID:23708917. |
bcl2l12 blocks effective caspase-3/7 maturation and inhibits p53 tumor suppressor, deriving resistance toward apoptosis and inducing extensive cell necrosis. |
2014-02-13 |
2023-08-12 |
Not clear |
| Yueshan Lei, Chengjun Hu, Hongxin Xu, Yihao Tia. HPV16 infection regulates RASSF1A transcription mediated by p53. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23779024. |
in the present study, we showed that hpv16-e6 selectively upregulates rassf1a expression via degradation of p53, which interacts with the rassf1a promoter and regulates apoptosis. |
2014-02-13 |
2023-08-12 |
human |
| Yueshan Lei, Chengjun Hu, Hongxin Xu, Yihao Tia. HPV16 infection regulates RASSF1A transcription mediated by p53. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23779024. |
overexpression of p53 triggered a decrease in endogenous rassf1a in siha cells, accompanied by apoptosis. |
2014-02-13 |
2023-08-12 |
human |
| Yueshan Lei, Chengjun Hu, Hongxin Xu, Yihao Tia. HPV16 infection regulates RASSF1A transcription mediated by p53. Molecular medicine reports. vol 8. issue 2. 2014-02-13. PMID:23779024. |
similarly, knockdown of endogenous hpv16-e6 in siha cells with rna interference (rnai) led to downregulation of rassf1a mediated by p53 and the subsequent induction of apoptosis. |
2014-02-13 |
2023-08-12 |
human |
| D S Vasconcelos, F P E da Silva, L G Quintana, N P Anselmo, M A K Othman, T Liehr, E H C de Oliveir. Numerical aberrations of chromosome 17 and TP53 in brain metastases derived from breast cancer. Genetics and molecular research : GMR. vol 12. issue 3. 2014-02-12. PMID:23315874. |
loss of p53 protein function influences not only cell cycle checkpoint controls and apoptosis, but also the regulation of other important stages of metastatic progression, such as cell migration and tissue invasion. |
2014-02-12 |
2023-08-12 |
human |
| Cornelia Braicu, Valentina Pileczki, Alexandru Irimie, Ioana Berindan-Neago. p53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cells. Molecular and cellular biochemistry. vol 381. issue 1-2. 2014-02-12. PMID:23881244. |
earlier reports proved that human breast cancer cells expressing mutant p53 displayed resistance to apoptosis. |
2014-02-12 |
2023-08-12 |
human |