| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammad Reza Ahmadianpour, Parviz Abdolmaleki, Seyed Javad Mowla, Saman Hosseinkhan. Static magnetic field of 6 mT induces apoptosis and alters cell cycle in p53 mutant Jurkat cells. Electromagnetic biology and medicine. vol 32. issue 1. 2014-04-15. PMID:23320430. |
static magnetic field of 6 mt induces apoptosis and alters cell cycle in p53 mutant jurkat cells. |
2014-04-15 |
2023-08-12 |
human |
| Mohammad Reza Ahmadianpour, Parviz Abdolmaleki, Seyed Javad Mowla, Saman Hosseinkhan. Static magnetic field of 6 mT induces apoptosis and alters cell cycle in p53 mutant Jurkat cells. Electromagnetic biology and medicine. vol 32. issue 1. 2014-04-15. PMID:23320430. |
exposure of human p53 mutant jurkat cells to 6 mt smf resulted in apoptosis, which was detected by luminometric and flow cytometric analysis also, phosphorylated atm and e2f1 proteins were detected by western blot analysis. |
2014-04-15 |
2023-08-12 |
human |
| Feng Zhang, Zhiyi Zhang, Zhiyu Li. Effects of Huaier aqueous extract on proliferation and apoptosis in the melanoma cell line A875. Acta histochemica. vol 115. issue 7. 2014-04-15. PMID:23601357. |
p53 expression was increased and cell apoptosis executed by caspase-3. |
2014-04-15 |
2023-08-12 |
Not clear |
| Joo-Yun Yim, Su-Jin Yang, Jun-Mo Yim, Min-Young Song, Hye-Won Rho, Sung Kyun Yim, Yeon-Hee Han, So Yeon Jeon, Hee Sun Kim, Ho-Young Yhim, Na-Ri Lee, Eun-Kee Song, Jae-Yong Kwak, Myung-Hee Sohn, Chang-Yeol Yi. Lymphocyte-mediated macrophage apoptosis during IL-12 stimulation. Cytokine. vol 64. issue 1. 2014-04-15. PMID:23953854. |
the endogenously produced no inhibited macrophage proliferation, and induced apoptosis in concordance with the accumulation of p53, phosphatase and tensin homologue deleted on chromosome 10 (pten) and dr5, and the activation of caspase-3, processes that were inhibited by n(g)-monomethyl-l-arginine, aminoguanidine (no synthase inhibitors) and 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (an no scavenger). |
2014-04-15 |
2023-08-12 |
mouse |
| Hassan Malekinejad, Masumeh Moradi, Johanna Fink-Gremmel. Cytochrome C and Caspase-3/7 are Involved in Mycophenolic Acid- Induced Apoptosis in Genetically Engineered PC12 Neuronal Cells Expressing the p53 gene. Iranian journal of pharmaceutical research : IJPR. vol 13. issue 1. 2014-04-15. PMID:24734071. |
cytochrome c and caspase-3/7 are involved in mycophenolic acid- induced apoptosis in genetically engineered pc12 neuronal cells expressing the p53 gene. |
2014-04-15 |
2023-08-13 |
Not clear |
| Punithavathi Ranganathan, Calpurnia Jayakumar, Sutip Navankasattusas, Dean Y Li, Il-man Kim, Ganesan Rames. UNC5B receptor deletion exacerbates tissue injury in response to AKI. Journal of the American Society of Nephrology : JASN. vol 25. issue 2. 2014-04-14. PMID:24115477. |
after aki, however, unc5b(-/flox/ggt-cre) mice exhibited significantly worse renal function and damage, increased tubular apoptosis, enhanced p53 activation, and exacerbated inflammation compared with unc5b(-/flox) and wild-type mice. |
2014-04-14 |
2023-08-12 |
mouse |
| Xiaoxiang Guan, Zhensheng Liu, Luo Wang, David G Johnson, Qingyi We. Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif. Biochemical and biophysical research communications. vol 443. issue 4. 2014-04-14. PMID:24388982. |
we also found that prohibitin and prohibiton up-regulated pig3 transcription independent of p53, although p53 obviously enhanced this process, and that the knock-down of prohibitin and prohibiton inhibited camptothecin-induced apoptosis. |
2014-04-14 |
2023-08-12 |
Not clear |
| Amanda Polson, David Reisma. The bidirectional p53-Wrap53β promoter is controlled by common cis- and trans-regulatory elements. Gene. vol 538. issue 1. 2014-04-11. PMID:24418698. |
the p53 protein is an important tumor suppressor that regulates many cellular processes including maintenance of the cell cycle and apoptosis. |
2014-04-11 |
2023-08-12 |
Not clear |
| b' L Ashley Watson, Xu Wang, Adrienne Elbert, Kristin D Kernohan, Niels Galjart, Nathalie G B\\xc3\\xa9rub\\xc3\\xa. Dual effect of CTCF loss on neuroprogenitor differentiation and survival. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 8. 2014-04-10. PMID:24553927.' |
cre-mediated ctcf deletion in the telencephalon and anterior retina at embryonic day 8.5 triggered upregulation of the p53 effector puma (p53 upregulated modulator of apoptosis), resulting in massive apoptosis and profound ablation of telencephalic structures. |
2014-04-10 |
2023-08-12 |
mouse |
| Rie Takahashi, Svetomir N Markovic, Heidi J Scrabl. Dominant effects of Δ40p53 on p53 function and melanoma cell fate. The Journal of investigative dermatology. vol 134. issue 3. 2014-04-09. PMID:24037342. |
we found that exogenous Δ40p53 caused apoptosis and increased the levels of endogenous, activated p53 in both cancerous and non-cancerous cells, which led to significant levels of cell death, particularly in cancer cells. |
2014-04-09 |
2023-08-12 |
Not clear |
| Rie Takahashi, Svetomir N Markovic, Heidi J Scrabl. Dominant effects of Δ40p53 on p53 function and melanoma cell fate. The Journal of investigative dermatology. vol 134. issue 3. 2014-04-09. PMID:24037342. |
Δ40p53 altered the promoter occupancy of these downstream p53 target genes in such a way that it shifted cell fate toward apoptosis and away from cell cycle arrest. |
2014-04-09 |
2023-08-12 |
Not clear |
| Amit Sharma, Kumar Saurabh, Sanjay Yadav, Swatantra K Jain, Devendra Parma. Expression profiling of selected genes of toxication and detoxication pathways in peripheral blood lymphocytes as a biomarker for predicting toxicity of environmental chemicals. International journal of hygiene and environmental health. vol 216. issue 6. 2014-04-08. PMID:23273579. |
these inducers were found to increase the expression of various phase ii enzymes such as glutathione s-transferases, gsts (gstm1, gsta1, gstp1 and gstk1), nqo1, ephx1 and sod1, genes involved in inflammation and apoptosis (p53, bcl2, apaf1 and caspase9) in both pbl and liver. |
2014-04-08 |
2023-08-12 |
rat |
| Angelo D'Alessandro, Cristina Marrocco, Sara Rinalducci, Angelo Peschiaroli, Anna Maria Timperio, Lucilla Bongiorno-Borbone, Alessandro Finazzi Agrò, Gerry Melino, Lello Zoll. Analysis of TAp73-dependent signaling via omics technologies. Journal of proteome research. vol 12. issue 9. 2014-04-08. PMID:23919926. |
transactivation-proficient (ta) p73 is a transcription factor belonging to the p53 family, which regulates a variety of biological processes, including neurogenesis, differentiation, apoptosis, and dna damage checkpoint response. |
2014-04-08 |
2023-08-12 |
human |
| Ming Zeng, Fang Xiao, Xiali Zhong, Feng Jin, Lan Guan, An Wang, Xinmin Liu, Caigao Zhon. Reactive oxygen species play a central role in hexavalent chromium-induced apoptosis in Hep3B cells without the functional roles of p53 and caspase-3. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 32. issue 2. 2014-04-08. PMID:23942225. |
reactive oxygen species play a central role in hexavalent chromium-induced apoptosis in hep3b cells without the functional roles of p53 and caspase-3. |
2014-04-08 |
2023-08-12 |
Not clear |
| Ming Zeng, Fang Xiao, Xiali Zhong, Feng Jin, Lan Guan, An Wang, Xinmin Liu, Caigao Zhon. Reactive oxygen species play a central role in hexavalent chromium-induced apoptosis in Hep3B cells without the functional roles of p53 and caspase-3. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 32. issue 2. 2014-04-08. PMID:23942225. |
although it is supported by a large body of literatures that p53 and caspase-3 played key roles in cr(vi)-induced cytotoxicity, it is clear that cr(vi) could induce apoptosis either without activating caspase, or in a p53- independent manner. |
2014-04-08 |
2023-08-12 |
Not clear |
| Esha Madan, Rajan Gogna, Bernhard Keppler, Uttam Pat. p53 increases intra-cellular calcium release by transcriptional regulation of calcium channel TRPC6 in GaQ3-treated cancer cells. PloS one. vol 8. issue 8. 2014-04-08. PMID:23976973. |
this research work shows that p53 and its transcriptional activity is critical in regulation of calcium signaling and an increase in the intracellular calcium level might be one of the anti-cancer strategies to induce apoptosis in cancer cells. |
2014-04-08 |
2023-08-12 |
Not clear |
| Qinglei Zhan, Sauna Tsai, Yonghai Lu, Chunmei Wang, Yiuwa Kwan, Saiming Nga. RuvBL2 is involved in histone deacetylase inhibitor PCI-24781-induced cell death in SK-N-DZ neuroblastoma cells. PloS one. vol 8. issue 8. 2014-04-08. PMID:23977108. |
treatment of sk-n-dz with pci-24781 also induced cell cycle arrest in g2/m phase and activated apoptosis signaling pathways via the up-regulation of dr4, p21, p53 and caspase 3. |
2014-04-08 |
2023-08-12 |
Not clear |
| Pei Du, Fangqiang Tang, Yaling Qiu, Fan Don. GFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis. PloS one. vol 8. issue 9. 2014-04-08. PMID:24023884. |
gfi1 is repressed by p53 and inhibits dna damage-induced apoptosis. |
2014-04-08 |
2023-08-12 |
Not clear |
| Claire Novorol, Janina Burkhardt, Kirstin J Wood, Anila Iqbal, Claudio Roque, Nicola Coutts, Alexandra D Almeida, Jie He, Christopher J Wilkinson, William A Harri. Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression. Open biology. vol 3. issue 10. 2014-04-08. PMID:24153002. |
there was also increased apoptosis in all the mcph models but this appears to be secondary to the mitotic defect as we frequently saw mitotically arrested cells disappear, and knocking down p53 apoptosis did not rescue the mitotic phenotype, either in whole retinas or clones. |
2014-04-08 |
2023-08-12 |
zebrafish |
| Liang-ming Liu, Shui-lin Sun, Chang-gen Ye, Dong-yu Liang, Liang Zhao, Fang-ping Yu, Ji-xiang Zhan. [Inhibitive mechanisms of Pim-3 affecting fulminant hepatic apoptosis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 20. issue 9. 2014-04-07. PMID:23207234. |
the pim-3 gene can block fulminant hepatic apoptosis by affecting the expression of the inos liver injury gene and the p53, bax and bcl-2 apoptosis-related genes. |
2014-04-07 |
2023-08-12 |
mouse |