| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Zhang, Rui Song, Yanfei Li, Jian Feng, Luying Peng, Jue L. Integration of microarray profiles associated with cardiomyopathy and the potential role of Ube3a in apoptosis. Molecular medicine reports. vol 9. issue 2. 2014-08-26. PMID:24337433. |
the results of this study indicate the efficiency of the data integration and the significant interrelation between ube3a and p53 in myocardial cells during apoptosis. |
2014-08-26 |
2023-08-12 |
Not clear |
| Xiaobin Cui, Zhimin Zhao, Dong Liu, Tao Guo, Su Li, Jianming Hu, Chunxia Liu, Lan Yang, Yuwen Cao, Jinfang Jiang, Weihua Liang, Wei Liu, Shugang Li, Lianghai Wang, Lidong Wang, Wenyi Gu, Chuanyue Wu, Yunzhao Chen, Feng L. Inactivation of miR-34a by aberrant CpG methylation in Kazakh patients with esophageal carcinoma. Journal of experimental & clinical cancer research : CR. vol 33. 2014-08-26. PMID:24528540. |
mir-34a, a direct p53 target gene, possesses tumor-suppressive properties as they mediate apoptosis, cell cycle arrest, and senescence. |
2014-08-26 |
2023-08-12 |
Not clear |
| Barbara Nuvoli, Raffaela Santoro, Simona Catalani, Serafina Battistelli, Serena Benedetti, Franco Canestrari, Rossella Galat. CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways. Journal of experimental & clinical cancer research : CR. vol 33. 2014-08-26. PMID:24598211. |
cellfood™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pakt signaling pathways. |
2014-08-26 |
2023-08-12 |
human |
| Z T Gu, H Wang, L Li, Y S Liu, X B Deng, S F Huo, F F Yuan, Z F Liu, H S Tong, L S. Heat stress induces apoptosis through transcription-independent p53-mediated mitochondrial pathways in human umbilical vein endothelial cell. Scientific reports. vol 4. 2014-08-26. PMID:24667845. |
we further revealed that p53 played a crucial role in heat stress-induced early apoptosis, with p53 protein rapidly translocated into mitochondria. |
2014-08-26 |
2023-08-12 |
human |
| Z T Gu, H Wang, L Li, Y S Liu, X B Deng, S F Huo, F F Yuan, Z F Liu, H S Tong, L S. Heat stress induces apoptosis through transcription-independent p53-mediated mitochondrial pathways in human umbilical vein endothelial cell. Scientific reports. vol 4. 2014-08-26. PMID:24667845. |
in addition, the antioxidant mntmpyp significantly decreased the heat stress-induced p53's mitochondrial translocation, followed by the loss of ΔΨm, cytochrome c release, caspase-9 activation and heat stress-mediated apoptosis. |
2014-08-26 |
2023-08-12 |
human |
| Z T Gu, H Wang, L Li, Y S Liu, X B Deng, S F Huo, F F Yuan, Z F Liu, H S Tong, L S. Heat stress induces apoptosis through transcription-independent p53-mediated mitochondrial pathways in human umbilical vein endothelial cell. Scientific reports. vol 4. 2014-08-26. PMID:24667845. |
conclusively, these findings indicate the contribution of the transcription-independent mitochondrial p53 pathway to early apoptosis in huvec cells induced by oxidative stress in response to intense heat stress. |
2014-08-26 |
2023-08-12 |
human |
| Ariele Viacava Follis, Fabien Llambi, Li Ou, Katherine Baran, Douglas R Green, Richard W Kriwack. The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nature structural & molecular biology. vol 21. issue 6. 2014-08-26. PMID:24814347. |
under conditions of genotoxic stress, human p53 activates the apoptotic effectors bax or bak to result in mitochondrial outer-membrane permeabilization and apoptosis. |
2014-08-26 |
2023-08-13 |
human |
| Ariele Viacava Follis, Fabien Llambi, Li Ou, Katherine Baran, Douglas R Green, Richard W Kriwack. The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nature structural & molecular biology. vol 21. issue 6. 2014-08-26. PMID:24814347. |
here we characterized the bcl-xl-p53 complex by nmr spectroscopy and modulated it through mutagenesis to determine the relative contributions of bcl-xl's interactions with p53 or other bcl-2 family proteins to the bcl-xl-dependent inhibition of uv irradiation-induced apoptosis. |
2014-08-26 |
2023-08-13 |
human |
| Ariele Viacava Follis, Fabien Llambi, Li Ou, Katherine Baran, Douglas R Green, Richard W Kriwack. The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nature structural & molecular biology. vol 21. issue 6. 2014-08-26. PMID:24814347. |
our studies define the contributions of cytosolic p53 to uv irradiation-induced apoptosis and provide opportunities to explore its contributions to other p53-dependent apoptotic signaling pathways. |
2014-08-26 |
2023-08-13 |
human |
| Anthony H V Schapira, C Warren Olanow, J Timothy Greenamyre, Erwan Bezar. Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives. Lancet (London, England). vol 384. issue 9942. 2014-08-26. PMID:24954676. |
in huntington's disease, strategies might also be directed at mitochondrial bioenergetics and turnover, the prevention of protein dysregulation, disruption of the interaction between huntingtin and p53 or huntingtin-interacting protein 1 to reduce apoptosis, and interference with expression of mutant huntingtin at both the nucleic acid and protein levels. |
2014-08-26 |
2023-08-13 |
Not clear |
| Zhaoying Qian, Tao Liu, Qiao Liu, Shulin He, Yongjie Liu, Fujun Hou, Xianzong Wang, Xiao Mi, Chen Cai, Xiaolin Li. p53 is involved in shrimp survival via its regulation roles on MnSOD and GPx in response to acute environmental stresses. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 159. 2014-08-22. PMID:24120750. |
once activated by a variety of cellular stresses, p53 transactivates downstream target genes, through which it regulates cell cycle and apoptosis. |
2014-08-22 |
2023-08-12 |
Not clear |
| Da-Guang Wang, Ya-Bin Sun, Fei Ye, Wei Li, Punyaram Kharbuja, Ling Gao, David Y Zhang, Jian Su. Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells. Molecular and cellular biochemistry. vol 386. issue 1-2. 2014-08-21. PMID:24136460. |
ppa analysis showed that embelin modulated several pathways that are associated with cell growth and apoptosis, such as pi3k/akt, jak/stat, p38 mapk, and p53. |
2014-08-21 |
2023-08-12 |
human |
| Toshihide Kato, Takaaki Fujii, Munenori Ide, Takahiro Takada, Toshinaga Sutoh, Hiroki Morita, Reina Yajima, Satoru Yamaguchi, Soichi Tsutsumi, Takayuki Asao, Tetsunari Oyama, Hiroyuki Kuwan. Effect of long interval between hyperthermochemoradiation therapy and surgery for rectal cancer on apoptosis, proliferation and tumor response. Anticancer research. vol 34. issue 6. 2014-08-21. PMID:24922685. |
in the current study we assessed the effect of a longer (>10 weeks) interval after neoadjuvant hcrt on pathological response, oncological outcome and especially on apoptosis, proliferation and p53 expression in patients with rectal cancer. |
2014-08-21 |
2023-08-13 |
Not clear |
| Toshihide Kato, Takaaki Fujii, Munenori Ide, Takahiro Takada, Toshinaga Sutoh, Hiroki Morita, Reina Yajima, Satoru Yamaguchi, Soichi Tsutsumi, Takayuki Asao, Tetsunari Oyama, Hiroyuki Kuwan. Effect of long interval between hyperthermochemoradiation therapy and surgery for rectal cancer on apoptosis, proliferation and tumor response. Anticancer research. vol 34. issue 6. 2014-08-21. PMID:24922685. |
furthermore, apoptosis in the long-interval group was relatively higher compared to that of the short-interval group, without a significant difference in the ki-67 proliferative index and expression of p53 in the primary tumor. |
2014-08-21 |
2023-08-13 |
Not clear |
| Toshihide Kato, Takaaki Fujii, Munenori Ide, Takahiro Takada, Toshinaga Sutoh, Hiroki Morita, Reina Yajima, Satoru Yamaguchi, Soichi Tsutsumi, Takayuki Asao, Tetsunari Oyama, Hiroyuki Kuwan. Effect of long interval between hyperthermochemoradiation therapy and surgery for rectal cancer on apoptosis, proliferation and tumor response. Anticancer research. vol 34. issue 6. 2014-08-21. PMID:24922685. |
in conclusion, we demonstrated that a longer interval after hcrt (>10 weeks) seemed to result in a better chance of a pcr, a result confirmed by the trends in tumor response markers, including apoptosis, proliferation and p53 expression. |
2014-08-21 |
2023-08-13 |
Not clear |
| Chen Qi, Shaowei Li, Yuchen Jia, Li Wan. [Blueberry anthocyanins induce G2/M cell cycle arrest and apoptosis of oral cancer KB cells through down-regulation methylation of p53]. Yi chuan = Hereditas. vol 36. issue 6. 2014-08-21. PMID:24929515. |
[blueberry anthocyanins induce g2/m cell cycle arrest and apoptosis of oral cancer kb cells through down-regulation methylation of p53]. |
2014-08-21 |
2023-08-13 |
Not clear |
| Shixing Wu, Bin Liu, Qingyu Zhang, Jie Liu, Wei Zhou, Chang Wang, Mingyi Li, Shiting Bao, Runzhi Zh. Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells. PloS one. vol 8. issue 11. 2014-08-20. PMID:24223706. |
in this study, we investigated whether p53 is involved in dhm-triggered viability inhibition and apoptosis induction in cancer cells. |
2014-08-20 |
2023-08-12 |
human |
| Shixing Wu, Bin Liu, Qingyu Zhang, Jie Liu, Wei Zhou, Chang Wang, Mingyi Li, Shiting Bao, Runzhi Zh. Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells. PloS one. vol 8. issue 11. 2014-08-20. PMID:24223706. |
these findings defined and supported a novel function that dhm could induce human hepatocellular carcinoma hepg2 cells apoptosis by up-regulating bax/bcl-2 expression via p53 signal pathway. |
2014-08-20 |
2023-08-12 |
human |
| Qian Cheng, Xiaoxiao Cao, Fuwen Yuan, Guodong Li, Tanjun Ton. Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53. Biochemical and biophysical research communications. vol 448. issue 3. 2014-08-20. PMID:24792179. |
knockdown of wwp1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53. |
2014-08-20 |
2023-08-13 |
human |
| Qian Cheng, Xiaoxiao Cao, Fuwen Yuan, Guodong Li, Tanjun Ton. Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53. Biochemical and biophysical research communications. vol 448. issue 3. 2014-08-20. PMID:24792179. |
knocking down wwp1 promoted cleaved caspase3 protein and p53 expression in hcc cells, and caspase3 inhibition could prevent cell apoptosis induced by the knockdown of wwp1. |
2014-08-20 |
2023-08-13 |
human |