| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ovidiu Braicu, Valentina Pileczki, Cornelia Braicu, Patriciu Achimas-Cadariu, Alexandru Irimie, Ioana Berindan-Neago. p53 siRNA - a therapeutic tool with significant implication in the modulation of apoptosis and angiogenic pathways. Clujul medical (1957). vol 88. issue 3. 2015-11-26. PMID:26609266. |
p53 sirna - a therapeutic tool with significant implication in the modulation of apoptosis and angiogenic pathways. |
2015-11-26 |
2023-08-13 |
Not clear |
| Ovidiu Braicu, Valentina Pileczki, Cornelia Braicu, Patriciu Achimas-Cadariu, Alexandru Irimie, Ioana Berindan-Neago. p53 siRNA - a therapeutic tool with significant implication in the modulation of apoptosis and angiogenic pathways. Clujul medical (1957). vol 88. issue 3. 2015-11-26. PMID:26609266. |
targeting oncogenic signals, as the mutated p53 gene that gains oncogenic role, we observed inhibition of migration, a downregulation of specific genes involved in apoptosis but also in angiogenesis, connected with a reduction in invasion rate in the case of p53sirna therapy. |
2015-11-26 |
2023-08-13 |
Not clear |
| Yoshihisa Sakai, Bernd Sokolowsk. The large conductance calcium-activated potassium channel affects extrinsic and intrinsic mechanisms of apoptosis. Journal of neuroscience research. vol 93. issue 5. 2015-11-25. PMID:25581503. |
hek cells that stably express bk are more resistant to apoptosis when p53 or fadd is overexpressed or when their intrinsic and extrinsic pathways are stimulated via mitomycin c or tumor necrosis factor-related apoptosis-inducing ligand (trail), respectively. |
2015-11-25 |
2023-08-13 |
mouse |
| Yoshihisa Sakai, Bernd Sokolowsk. The large conductance calcium-activated potassium channel affects extrinsic and intrinsic mechanisms of apoptosis. Journal of neuroscience research. vol 93. issue 5. 2015-11-25. PMID:25581503. |
these data suggest that bk is part of a larger complex of proteins that protects against apoptosis by interacting with proapoptotic proteins, such as p53 and fadd. |
2015-11-25 |
2023-08-13 |
mouse |
| Wang Miao, Xiaodong Liu, Hongqin Wang, Yimin Fan, Shizhong Lian, Xin Yang, Xinxing Wang, Geng Guo, Qichao Li, Sifei Wan. p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis. Molecular medicine reports. vol 11. issue 6. 2015-11-25. PMID:25625235. |
p53 upregulated modulator of apoptosis sensitizes drug-resistant u251 glioblastoma stem cells to temozolomide through enhanced apoptosis. |
2015-11-25 |
2023-08-13 |
Not clear |
| Wang Miao, Xiaodong Liu, Hongqin Wang, Yimin Fan, Shizhong Lian, Xin Yang, Xinxing Wang, Geng Guo, Qichao Li, Sifei Wan. p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis. Molecular medicine reports. vol 11. issue 6. 2015-11-25. PMID:25625235. |
tmz achieves its cytotoxic effect by inducing dna lesions and p53 upregulated modulator of apoptosis (puma) is an essential mediator of dna damage‑induced apoptosis independently of p53 status. |
2015-11-25 |
2023-08-13 |
Not clear |
| Animesh Bhattacharya, Ulf Schmitz, Yvonne Raatz, Madeleine Schönherr, Tina Kottek, Marianne Schauer, Sandra Franz, Anja Saalbach, Ulf Anderegg, Olaf Wolkenhauer, Dirk Schadendorf, Jan C Simon, Thomas Magin, Julio Vera, Manfred Kun. miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy. Oncotarget. vol 6. issue 5. 2015-11-25. PMID:25650662. |
depletion of mir-638 stimulated expression of p53 and p53 downstream target genes and induced apoptosis and autophagy. |
2015-11-25 |
2023-08-13 |
Not clear |
| Shanshan Chen, Ping Li, Juan Li, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Wenqiao Zang, Huaqi Wang, Heying Chu, Guoqiang Zhao, Guojun Zhan. MiR-144 inhibits proliferation and induces apoptosis and autophagy in lung cancer cells by targeting TIGAR. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 35. issue 3. 2015-11-25. PMID:25660220. |
the p53-induced glycolysis and apoptosis regulator (tigar) was discovered through microarray analysis of gene expression following activation of p53. |
2015-11-25 |
2023-08-13 |
Not clear |
| Xingxing He, Fang Liu, Jingjun Yan, Yunan Zhang, Junwei Yan, Haitao Shang, Qian Dou, Qiu Zhao, Yuhu Son. Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo. Scientific reports. vol 5. 2015-11-25. PMID:25732051. |
phenotypic changes of hcc cells induced by p53-ptm were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. |
2015-11-25 |
2023-08-13 |
mouse |
| Murat Tosun, Mehmet Yucel, Aysegul Kucuk, Saban Seze. P53 related apoptosis in kidneys in CO₂ pneumoperitoneum rat model: an immunohistochemical study. Molecular biology reports. vol 41. issue 10. 2015-11-24. PMID:25034890. |
p53 related apoptosis in kidneys in co₂ pneumoperitoneum rat model: an immunohistochemical study. |
2015-11-24 |
2023-08-13 |
rat |
| Murat Tosun, Mehmet Yucel, Aysegul Kucuk, Saban Seze. P53 related apoptosis in kidneys in CO₂ pneumoperitoneum rat model: an immunohistochemical study. Molecular biology reports. vol 41. issue 10. 2015-11-24. PMID:25034890. |
the aim of this study is to evaluate the effects of different pressures of co2 on p53 related apoptosis in kidneys. |
2015-11-24 |
2023-08-13 |
rat |
| Murat Tosun, Mehmet Yucel, Aysegul Kucuk, Saban Seze. P53 related apoptosis in kidneys in CO₂ pneumoperitoneum rat model: an immunohistochemical study. Molecular biology reports. vol 41. issue 10. 2015-11-24. PMID:25034890. |
at last, the kidneys were excised and p53 expression and apoptosis were evaluated immunohistochemically. |
2015-11-24 |
2023-08-13 |
rat |
| Mi-Kyung Yoon, Ji-Hyang Ha, Min-Sung Lee, Seung-Wook Ch. Structure and apoptotic function of p73. BMB reports. vol 48. issue 2. 2015-11-24. PMID:25441426. |
like p53, p73 induces apoptosis and cell cycle arrest and transactivates p53-responsive genes, conferring its tumor suppressive activity. |
2015-11-24 |
2023-08-13 |
human |
| Mi-Kyung Yoon, Ji-Hyang Ha, Min-Sung Lee, Seung-Wook Ch. Structure and apoptotic function of p73. BMB reports. vol 48. issue 2. 2015-11-24. PMID:25441426. |
the importance of p73-induced apoptosis lies in its capability to substitute the pro-apoptotic activity of p53 in various human cancer cells in which p53 is mutated or inactive. |
2015-11-24 |
2023-08-13 |
human |
| Mi-Kyung Yoon, Ji-Hyang Ha, Min-Sung Lee, Seung-Wook Ch. Structure and apoptotic function of p73. BMB reports. vol 48. issue 2. 2015-11-24. PMID:25441426. |
in this review, we discuss the p73 structures reported to date, detailed structural comparisons between p73 and p53, and current understanding of the transcription-dependent and -independent mechanisms of p73-induced apoptosis. |
2015-11-24 |
2023-08-13 |
human |
| Rohit Seth, Rikki S Corniola, Shannon D Gower-Winter, Thomas J Morgan, Brian Bishop, Cathy W Levenso. Zinc deficiency induces apoptosis via mitochondrial p53- and caspase-dependent pathways in human neuronal precursor cells. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 30. 2015-11-24. PMID:25467851. |
together these data identify a cascade of events involving mitochondrial p53 as well as p53-dependent caspase-mediated mechanisms leading to apoptosis during zinc deficiency. |
2015-11-24 |
2023-08-13 |
human |
| Yuanhong Liao, Jianya Ling, Guoying Zhang, Fengjun Liu, Shengce Tao, Zeguang Han, Saijuan Chen, Zhu Chen, Huangying L. Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells. Cell cycle (Georgetown, Tex.). vol 14. issue 5. 2015-11-24. PMID:25590866. |
cordycepin induces cell cycle arrest and apoptosis by inducing dna damage and up-regulation of p53 in leukemia cells. |
2015-11-24 |
2023-08-13 |
Not clear |
| Oluwafunmilayo F Lamidi, Monica Sani, Paolo Lazzari, Matteo Zanda, Ian N Flemin. The tubulysin analogue KEMTUB10 induces apoptosis in breast cancer cells via p53, Bim and Bcl-2. Journal of cancer research and clinical oncology. vol 141. issue 9. 2015-11-24. PMID:25633717. |
the tubulysin analogue kemtub10 induces apoptosis in breast cancer cells via p53, bim and bcl-2. |
2015-11-24 |
2023-08-13 |
Not clear |
| Xue-Ya Zhang, Shi-Xin Wu, Xi-Zhe Guo, Jing-Xin Pa. [2-methoxyestradiol induced apoptosis and expression of p53 gene in human acute T lymphoblastic leukemia cells]. Zhongguo shi yan xue ye xue za zhi. vol 23. issue 2. 2015-11-24. PMID:25948191. |
[2-methoxyestradiol induced apoptosis and expression of p53 gene in human acute t lymphoblastic leukemia cells]. |
2015-11-24 |
2023-08-13 |
human |
| Yassine Chtourou, Bakhta Aouey, Mohammed Kebieche, Hamadi Fetou. Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-κB and P53 signaling pathways. Chemico-biological interactions. vol 239. 2015-11-24. PMID:26120027. |
protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ros-mediated nf-κb and p53 signaling pathways. |
2015-11-24 |
2023-08-13 |
rat |