| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hsuan-Shun Huang, Sung-Chao Chu, Che-Fang Hsu, Pao-Chu Chen, Dah-Ching Ding, Meng-Ya Chang, Tang-Yuan Ch. Mutagenic, surviving and tumorigenic effects of follicular fluid in the context of p53 loss: initiation of fimbria carcinogenesis. Carcinogenesis. vol 36. issue 11. 2016-02-03. PMID:26363031. |
when p53 and rb were turned down, the ff-exposed secretory cells overcame apoptosis and expanded the population carrying ros and dsb. |
2016-02-03 |
2023-08-13 |
mouse |
| Alyse N Douglass, Heather S Kain, Marian Abdullahi, Nadia Arang, Laura S Austin, Sebastian A Mikolajczak, Zachary P Billman, Jen C C Hume, Sean C Murphy, Stefan H I Kappe, Alexis Kaushansk. Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites. Molecular therapy : the journal of the American Society of Gene Therapy. vol 23. issue 5. 2016-02-02. PMID:25648263. |
bcl-2 inhibitors act primarily by inducing apoptosis in infected hepatocytes, whereas p53 agonists eliminate parasites in an apoptosis-independent fashion. |
2016-02-02 |
2023-08-13 |
mouse |
| Sook Hyun Chung, Mark Gillies, Yuki Sugiyama, Ling Zhu, So-Ra Lee, Weiyong She. Profiling of microRNAs involved in retinal degeneration caused by selective Müller cell ablation. PloS one. vol 10. issue 3. 2016-02-02. PMID:25741709. |
david and kegg pathway analysis suggested that the target genes were generally involved in cell apoptosis, p53, neurotrophin, calcium, chemokine and jak-stat signalling pathways. |
2016-02-02 |
2023-08-13 |
Not clear |
| Erika Mikulenkova, Jakub Neradil, Karel Zitterbart, Jaroslav Sterba, Renata Veselsk. Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 10. 2016-02-02. PMID:25910708. |
the p73 protein is a member of the p53 family, and this protein is known to be essential for the maintenance of genomic stability, dna repair, and apoptosis regulation. |
2016-02-02 |
2023-08-13 |
Not clear |
| John J Tentler, Anastasia A Ionkina, Aik Choon Tan, Timothy P Newton, Todd M Pitts, Magdalena J Glogowska, Peter Kabos, Carol A Sartorius, Kelly D Sullivan, Joaquin M Espinosa, S Gail Eckhardt, Jennifer R Diamon. p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer. Molecular cancer therapeutics. vol 14. issue 5. 2016-02-01. PMID:25758253. |
the induction of apoptosis in response to alisertib exposure was dependent on p53 and p73 activity. |
2016-02-01 |
2023-08-13 |
Not clear |
| John J Tentler, Anastasia A Ionkina, Aik Choon Tan, Timothy P Newton, Todd M Pitts, Magdalena J Glogowska, Peter Kabos, Carol A Sartorius, Kelly D Sullivan, Joaquin M Espinosa, S Gail Eckhardt, Jennifer R Diamon. p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer. Molecular cancer therapeutics. vol 14. issue 5. 2016-02-01. PMID:25758253. |
in the absence of functional p53 or p73, there was a shift in the phenotypic response following alisertib exposure from apoptosis to cellular senescence. |
2016-02-01 |
2023-08-13 |
Not clear |
| Isabel Diebold, Jan K Hennigs, Kazuya Miyagawa, Caiyun G Li, Nils P Nickel, Mark Kaschwich, Aiqin Cao, Lingli Wang, Sushma Reddy, Pin-I Chen, Kiichi Nakahira, Miguel A Alejandre Alcazar, Rachel K Hopper, Lijuan Ji, Brian J Feldman, Marlene Rabinovitc. BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension. Cell metabolism. vol 21. issue 4. 2016-02-01. PMID:25863249. |
decreasing paec bmpr2 by sirna during reoxygenation represses p53, pgc1α, nrf2, tfam, mitochondrial membrane potential, and atp and induces mitochondrial dna deletion and apoptosis. |
2016-02-01 |
2023-08-13 |
mouse |
| Nidhi Gera, Aaron Yang, Talia S Holtzman, Sze Xian Lee, Eric T Wong, Kenneth D Swanso. Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit. PloS one. vol 10. issue 5. 2016-02-01. PMID:26010837. |
after aberrant metaphase exit as a consequence of ttfields exposure, cells exhibited aberrant nuclear architecture and signs of cellular stress including an overall decrease in cellular proliferation, followed by apoptosis that was strongly influenced by the p53 mutational status. |
2016-02-01 |
2023-08-13 |
Not clear |
| Tomonao Inobe, Miyuki Nozaki, Nobuyuki Nukin. Artificial regulation of p53 function by modulating its assembly. Biochemical and biophysical research communications. vol 467. issue 2. 2016-02-01. PMID:26454170. |
the tumor suppressor p53, a 393-amino acid transcription factor with four domains, induces cell cycle arrest, senescence, and apoptosis in response to diverse stress. |
2016-02-01 |
2023-08-13 |
Not clear |
| Cen Chen, Huafeng Han, Wei Yang, Xiaoyuan Ren, Xiangdong Kon. Polyethyleneimine-modified calcium carbonate nanoparticles for p53 gene delivery. Regenerative biomaterials. vol 3. issue 1. 2016-01-28. PMID:26816656. |
meanwhile, the cytotoxicity, transfection efficiency, cells growth inhibition and the ability to induce apoptosis by expressed p53 protein were conducted to evaluate the performances of pei-caco3 nanoparticles. |
2016-01-28 |
2023-08-13 |
Not clear |
| Ceren Kizmazoglu, Hasan Emre Aydin, Ismail Ertan Sevin, Orhan Kalemci, Nurullah Yüceer, Metin Ant Ataso. Neuroprotective Effect of Resveratrol on Acute Brain Ischemia Reperfusion Injury by Measuring Annexin V, p53, Bcl-2 Levels in Rats. Journal of Korean Neurosurgical Society. vol 58. issue 6. 2016-01-28. PMID:26819684. |
there are some useful markers for apoptosis like bcl-2, bax, and p53. |
2016-01-28 |
2023-08-13 |
rat |
| Sergey Iordanskiy, Rachel Van Duyne, Gavin C Sampey, Caitlin M Woodson, Kelsi Fry, Mohammed Saifuddin, Jia Guo, Yuntao Wu, Fabio Romerio, Fatah Kashanch. Therapeutic doses of irradiation activate viral transcription and induce apoptosis in HIV-1 infected cells. Virology. vol 485. 2016-01-27. PMID:26184775. |
increased hiv-1 replication after ir correlated with higher cell death: the level of phosphorylated ser46 in p53, responsible for apoptosis induction, was markedly higher in the hiv-1 infected cells following ir treatment. |
2016-01-27 |
2023-08-13 |
mouse |
| Wenfeng Li, Shuangming Lin, Wenhuan Li, Weijun Wang, Xueming Li, Dongbo X. KDM3A interacted with p53K372me1 and regulated p53 binding to PUMA in gastric cancer. Biochemical and biophysical research communications. vol 467. issue 3. 2016-01-27. PMID:26431874. |
in our present study, we for the first time found that knock down of kdm3a can promote apoptosis induced by chemoreagent cisplatin and paclitaxel through p53. |
2016-01-27 |
2023-08-13 |
Not clear |
| Anna Kakehashi, Ayumi Kato, Naomi Ishii, Min Wei, Keiichirou Morimura, Shoji Fukushima, Hideki Wanibuch. Valerian inhibits rat hepatocarcinogenesis by activating GABA(A) receptor-mediated signaling. PloS one. vol 9. issue 11. 2016-01-26. PMID:25419570. |
cell proliferation was significantly inhibited, while apoptosis was induced in areas of gst-p(+) foci of valerian groups associated with suppression of c-myc, mafb, cyclin d1 and induction of p21(waf1/cip1), p53 and bax mrna expression. |
2016-01-26 |
2023-08-13 |
rat |
| Yashodhar P Bhandary, Shwetha K Shetty, Amarnath S Marudamuthu, Krishna K Midde, Hong-Long Ji, Homoyoun Shams, Renuka Subramaniam, Jian Fu, Steven Idell, Sreerama Shett. Plasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury. PloS one. vol 10. issue 5. 2016-01-26. PMID:25932922. |
we found increased p53, pai-1 and apoptosis in aecs, with accumulation of macrophages and neutrophils in the lungs of patients with copd. |
2016-01-26 |
2023-08-13 |
mouse |
| Yashodhar P Bhandary, Shwetha K Shetty, Amarnath S Marudamuthu, Krishna K Midde, Hong-Long Ji, Homoyoun Shams, Renuka Subramaniam, Jian Fu, Steven Idell, Sreerama Shett. Plasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury. PloS one. vol 10. issue 5. 2016-01-26. PMID:25932922. |
in wild-type (wt) mice with passive cse (pcse), p53 and pai-1 expression and apoptosis were increased in aecs as was lung inflammation, while those lacking p53 or pai-1 resisted aec apoptosis and lung inflammation. |
2016-01-26 |
2023-08-13 |
mouse |
| Yashodhar P Bhandary, Shwetha K Shetty, Amarnath S Marudamuthu, Krishna K Midde, Hong-Long Ji, Homoyoun Shams, Renuka Subramaniam, Jian Fu, Steven Idell, Sreerama Shett. Plasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury. PloS one. vol 10. issue 5. 2016-01-26. PMID:25932922. |
consistent with pcse-induced lung injury, iav infection increased p53, pai-1 and apoptosis in aecs in association with pulmonary inflammation. |
2016-01-26 |
2023-08-13 |
mouse |
| D Kramer, M Schön, M Bayerlová, A Bleckmann, M P Schön, M Zörnig, M Dobbelstei. A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity. Cell death & disease. vol 6. 2016-01-25. PMID:25675294. |
the p53 family and its cofactors are potent inducers of apoptosis and form a barrier to cancer. |
2016-01-25 |
2023-08-13 |
human |
| T-Y Kao, Y-C Chiu, W-C Fang, C-W Cheng, C-Y Kuo, H-F Juan, S-H Wu, A Y-L Le. Mitochondrial Lon regulates apoptosis through the association with Hsp60-mtHsp70 complex. Cell death & disease. vol 6. 2016-01-25. PMID:25675302. |
most importantly, the ability of increased lon-inhibited apoptosis is dependent on hsp60 that binds p53 to inhibit apoptosis. |
2016-01-25 |
2023-08-13 |
human |
| P J Ma, H Zhang, R Li, Y S Wang, Y Zhang, S Hu. P53-Mediated Repression of the Reprogramming in Cloned Bovine Embryos Through Direct Interaction with HDAC1 and Indirect Interaction with DNMT3A. Reproduction in domestic animals = Zuchthygiene. vol 50. issue 3. 2016-01-25. PMID:25753134. |
p53 is a transcriptional activator, regulating growth arrest, dna repair and apoptosis. |
2016-01-25 |
2023-08-13 |
cattle |