| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diana Gomes, Luís A Passarinha, Ângela Sous. E6 Tagged Protein Production, Extraction, and Purification from Escherichia coli Lysate. Methods in molecular biology (Clifton, N.J.). vol 2652. 2023-04-24. PMID:37093468. |
this protein can interfere with p53 tumor suppressor activity, blocking apoptosis of abnormal cells. |
2023-04-24 |
2023-08-14 |
human |
| Hui Zhou, Yuqin Liao, Xiangfei Han, Dean Shuailin Chen, Xuechuan Hong, Kun Zhou, Xingya Jiang, Yuling Xiao, Jinjun Sh. ROS-Responsive Nanoparticle Delivery of mRNA and Photosensitizer for Combinatorial Cancer Therapy. Nano letters. 2023-04-24. PMID:37093620. |
the ros-triggered disassembly of the nps could promote mrna translation efficiency, whereby p53 expression induced apoptosis of lung tumor cells. |
2023-04-24 |
2023-08-14 |
Not clear |
| Jia Guo, Zhi-Dong Li, Chuan-Shi Xiao, Yun-Fei Bia. [Effects of PUMA knockout on the apoptosis of H9C2 cardiomyocytes induced by high glucose]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 38. issue 5. 2023-04-23. PMID:37088760. |
to investigate the effects of p53 upregulated modulator of apoptosis (puma) on the apoptosis of h9c2 cardiomyocytes induced by high glucose and its mechanisms. |
2023-04-23 |
2023-08-14 |
Not clear |
| Yoon-Jin Lee, Kwan-Sik Park, Su-Hak Heo, Moon-Kyun Cho, Sang-Han Le. Concurrent induction of apoptosis and necroptosis in apigenin‑treated malignant mesothelioma cells: Reversal of Warburg effect through Akt inhibition and p53 upregulation. Oncology reports. vol 49. issue 6. 2023-04-21. PMID:37083070. |
concurrent induction of apoptosis and necroptosis in apigenin‑treated malignant mesothelioma cells: reversal of warburg effect through akt inhibition and p53 upregulation. |
2023-04-21 |
2023-08-14 |
Not clear |
| Bingxin Li, Yaqiong Ye, Longsheng Hong, Wanyan Li, Qingru Wu, Wenjun Liu, Yongjiang Ma, Danning Xu, Yugu L. Transcriptome analysis reveals a potential regulatory mechanism of the lnc-5423.6/IGFBP5 axis in the early stages of mouse thymic involution. Acta biochimica et biophysica Sinica. 2023-04-20. PMID:37078747. |
among them, igfbp5 can reduce the viability, inhibit proliferation and promote apoptosis of mouse medullary thymic epithelial cell line 1 (mtec1) cells through the p53 signaling pathway. |
2023-04-20 |
2023-08-14 |
mouse |
| Hong-Beom Park, Yosuk Min, Sohyun Hwang, Kwang-Hyun Bae. Suppression of USP7 negatively regulates the stability of ETS proto-oncogene 2 protein. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 162. 2023-04-16. PMID:37062218. |
moreover, it also known that usp7 functions in the cell cycle, apoptosis, dna repair, chromatin remodeling, and epigenetic regulation through deubiquitination of several substrates including p53, mouse double minute 2 homolog (mdm2), myc, and phosphatase and tensin homolog (pten). |
2023-04-16 |
2023-08-14 |
mouse |
| Yuehao Tan, Can Li, Jiali Zhou, Fengmei Deng, Yilun Li. Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis. Experimental cell research. 2023-04-16. PMID:37062521. |
bbr also markedly induced hsc apoptosis, as indicated by the upregulated expression of the pro-apoptosis markers p53, bax, and cleaved parp and the downregulated expression of the anti-apoptosis marker bcl-2, effects that were reversed by atg5 overexpression. |
2023-04-16 |
2023-08-14 |
mouse |
| Bardia Mortezagholi, Kamyar Nasiri, Emad Movahed, Esmaeel Dadgar, Seyedeh Tabasom Nejati, Pardis Hassani, Mahla Esfahaniani, Sona Rafieya. MiR-34 by targeting p53 induces apoptosis and DNA damage in paclitaxel-resistant human oral squamous carcinoma cells. Chemical biology & drug design. 2023-04-15. PMID:37060268. |
mir-34 by targeting p53 induces apoptosis and dna damage in paclitaxel-resistant human oral squamous carcinoma cells. |
2023-04-15 |
2023-08-14 |
human |
| Bardia Mortezagholi, Kamyar Nasiri, Emad Movahed, Esmaeel Dadgar, Seyedeh Tabasom Nejati, Pardis Hassani, Mahla Esfahaniani, Sona Rafieya. MiR-34 by targeting p53 induces apoptosis and DNA damage in paclitaxel-resistant human oral squamous carcinoma cells. Chemical biology & drug design. 2023-04-15. PMID:37060268. |
the chemosensitive effects of mir-34 is mediated through increasing dna damage and apoptosis in a p53 depended manner. |
2023-04-15 |
2023-08-14 |
human |
| Masumeh Sanaei, Fraidoon Kavoosi, Mohsen Safar. Effect of 5'-Fluoro-2'-Deoxycytidine and Sodium Butyrate on the Gene Expression of the Intrinsic Apoptotic Pathway, p21, p27, and p53 Genes Expression, Cell Viability, and Apoptosis in Human Hepatocellular Carcinoma Cell Lines. Advanced biomedical research. vol 12. 2023-04-14. PMID:37057236. |
effect of 5'-fluoro-2'-deoxycytidine and sodium butyrate on the gene expression of the intrinsic apoptotic pathway, p21, p27, and p53 genes expression, cell viability, and apoptosis in human hepatocellular carcinoma cell lines. |
2023-04-14 |
2023-08-14 |
human |
| Masumeh Sanaei, Fraidoon Kavoosi, Mohsen Safar. Effect of 5'-Fluoro-2'-Deoxycytidine and Sodium Butyrate on the Gene Expression of the Intrinsic Apoptotic Pathway, p21, p27, and p53 Genes Expression, Cell Viability, and Apoptosis in Human Hepatocellular Carcinoma Cell Lines. Advanced biomedical research. vol 12. 2023-04-14. PMID:37057236. |
this study aimed to investigate the effect of 5'-fluoro-2'-deoxycytidine (fdcyd) and sodium butyrate on the genes of intrinsic apoptotic pathway (bax, bak and apaf1, bcl-2, and bcl-xl), p21, p27, and p53 gene expression, cell viability, and apoptosis in human hepatocellular carcinoma hep3b, smmc-7721, and ha22t/vgh cell lines. |
2023-04-14 |
2023-08-14 |
human |
| Yuexin Wei, Yifan Hong, Liuqing Yang, Junke Wang, Tianxin Zhao, Xiangqin Zheng, Lian Kang, Jiadong Chen, Lindong Han, Chunlan Long, Lianju Shen, Shengde Wu, Guanghui We. Single-cell transcriptomic dissection of the toxic impact of di(2-ethylhexyl) phthalate on immature testicular development at the neonatal stage. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-04-14. PMID:37059381. |
elevated oxidative stress and excessive apoptosis mediated by p53 were observed in almost all testicular cells. |
2023-04-14 |
2023-08-14 |
mouse |
| Zhujiang Dai, Jie Zhang, Weimin Xu, Peng Du, Zhongchuan Wang, Yun Li. Single-Cell Sequencing-Based Validation of T Cell-Associated Diagnostic Model Genes and Drug Response in Crohn's Disease. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047025. |
tnf-centered 5-gene diagnostic model not only has excellent diagnostic efficacy, but is also closely associated with kras, p53, and il6/jak/stat3 pathways and physiological processes, such as emt, coagulation, and apoptosis. |
2023-04-13 |
2023-08-14 |
Not clear |
| Xue Wang, Yi Liu, Kaiyuan Li, Zhihui Ha. Roles of p53-Mediated Host-Virus Interaction in Coronavirus Infection. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047343. |
the p53 tumor suppressor molecule is a critical regulator of cell signaling pathways, cellular stress responses, dna repair, and apoptosis. |
2023-04-13 |
2023-08-14 |
Not clear |
| Songhao Tian, Huiting Zhao, Hongru Guo, Wei Feng, Conglin Jiang, Yusuo Jian. Propolis Ethanolic Extract Attenuates D-gal-induced C2C12 Cell Injury by Modulating Nrf2/HO-1 and p38/p53 Signaling Pathways. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047379. |
pee inhibited apoptosis by suppressing p38 phosphorylation and reducing p53 expression. |
2023-04-13 |
2023-08-14 |
mouse |
| Jian Xie, Qiuyi Chen, Yongxia Zhao, Mingxia Luo, Xin Zeng, Lin Qin, Daopeng Tan, Yuqi H. Transcriptome Sequencing Reveals Autophagy Networks in Rat Livers during the Development of NAFLD and Identifies Autophagy Hub Genes. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047411. |
go and kegg pathway analysis revealed that these degs were primarily involved in autophagy, cholesterol transport, triglyceride metabolism, apoptosis, the foxo signaling pathway, the p53 signaling pathway and the il-17 signaling pathway. |
2023-04-13 |
2023-08-14 |
mouse |
| Kealan McElhinney, Mustapha Irnaten, Colm O'Brie. p53 and Myofibroblast Apoptosis in Organ Fibrosis. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047710. |
p53 and myofibroblast apoptosis in organ fibrosis. |
2023-04-13 |
2023-08-14 |
Not clear |
| Kealan McElhinney, Mustapha Irnaten, Colm O'Brie. p53 and Myofibroblast Apoptosis in Organ Fibrosis. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047710. |
an enhanced understanding of the role of p53 dysregulation and myofibroblast apoptosis may aid in future novel therapeutic and/or diagnostic strategies in organ fibrosis. |
2023-04-13 |
2023-08-14 |
Not clear |
| Shantanu Gupta, Pritam Kumar Panda, Daner A Silveira, Rajeev Ahuja, Ronaldo F Hashimot. Quadra-Stable Dynamics of p53 and PTEN in the DNA Damage Response. Cells. vol 12. issue 7. 2023-04-13. PMID:37048159. |
our network's wild-type system shows that ddr activates the g2/m checkpoint, and this triggers a cascade of events, involving p53 and pten, that ultimately lead to the four potential phenotypes: cell cycle arrest, senescence, autophagy, and apoptosis (quadra-stable dynamics). |
2023-04-13 |
2023-08-14 |
Not clear |
| G Tchernev, S Kordeva, I Loze. METATYPICAL BCCS OF THE NOSE TREATED SUCCESSFULLY VIA BILOBED TRANSPOSITION FLAP: NITROSAMINES IN ACES (ENALAPRIL), ARBS (LOSARTAN) AS POSSIBLE SKIN CANCER KEY TRIGGERING FACTOR. Georgian medical news. issue 335. 2023-04-12. PMID:37042583. |
the pathogenesis of keratinocytic skin cancer has been well-studied over the years, with a main focus on the influence of uv radiation and the subsequent changes in the genome regulator p53, which affects the cell cycle and the programmed cell death, apoptosis. |
2023-04-12 |
2023-08-14 |
Not clear |