| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Sung Choi, Ji Hyeon Kim, Chae Yeon Lee, Yul Min Lee, Sukmook Lee, Ha Kyun Chang, Hyun Jung Kim, Kyun He. Gentian Violet Inhibits Cell Proliferation through Induction of Apoptosis in Ovarian Cancer Cells. Biomedicines. vol 11. issue 6. 2023-06-28. PMID:37371752. |
moreover, gv significantly increased reactive oxygen species (ros) and upregulated the expression of p53, puma, bax, and p21, critical components for apoptosis induction, in ovarian cancer cells. |
2023-06-28 |
2023-08-14 |
Not clear |
| Antonietta Notaro, Marianna Lauricella, Diana Di Liberto, Sonia Emanuele, Michela Giuliano, Alessandro Attanzio, Luisa Tesoriere, Daniela Carlisi, Mario Allegra, Anna De Blasio, Giuseppe Calvaruso, Antonella D'Anne. A Deadly Liaison between Oxidative Injury and p53 Drives Methyl-Gallate-Induced Autophagy and Apoptosis in HCT116 Colon Cancer Cells. Antioxidants (Basel, Switzerland). vol 12. issue 6. 2023-06-28. PMID:37372022. |
a deadly liaison between oxidative injury and p53 drives methyl-gallate-induced autophagy and apoptosis in hct116 colon cancer cells. |
2023-06-28 |
2023-08-14 |
Not clear |
| Ruibiao Wang, Lihao Lin, Yang Han, Zhixin Li, Jingbo Zhen, Yuheng Zhang, Feng Sun, Yixin L. Exosome-delivered miR-153 from Trichinella spiralis promotes apoptosis of intestinal epithelial cells by downregulating Bcl2. Veterinary research. vol 54. issue 1. 2023-06-28. PMID:37381058. |
moreover, studies have suggested that mir-153 can promote apoptosis by regulating the mapk and p53 signalling pathways involved in apoptosis. |
2023-06-28 |
2023-08-14 |
Not clear |
| Ruibiao Wang, Lihao Lin, Yang Han, Zhixin Li, Jingbo Zhen, Yuheng Zhang, Feng Sun, Yixin L. Exosome-delivered miR-153 from Trichinella spiralis promotes apoptosis of intestinal epithelial cells by downregulating Bcl2. Veterinary research. vol 54. issue 1. 2023-06-28. PMID:37381058. |
thus, exosome-mediated mir-153 delivery secreted by t. spiralis could induce apoptosis and affect the mapk and p53 signalling pathways by downregulating bcl2 in ipec-j2 cells. |
2023-06-28 |
2023-08-14 |
Not clear |
| Qianhui Li, Bumin Xie, Xi Chen, Bingfeng Lu, Shuo Chen, Xiujie Sheng, Yang Zha. SNORD6 promotes cervical cancer progression by accelerating E6-mediated p53 degradation. Cell death discovery. vol 9. issue 1. 2023-06-27. PMID:37369687. |
this reaction enhanced the ubiquitination and degradation of p53, thus influenced the regulation of p53 activities in the cell cycle and apoptosis. |
2023-06-27 |
2023-08-14 |
Not clear |
| Yiyang Sun, Lingling Zhang, Zhuoqing Fang, Dingyu Liu, Min Shao, Yujie Liu, Bing Liao, Ying Ji. PRPF8 controls alternative splicing of PIRH2 to modulate the p53 pathway and survival of human ESCs. Journal of cellular physiology. 2023-06-26. PMID:37357506. |
prpf8 knockdown (kd) induces p53 protein accumulation and activates the p53 pathway, leading to apoptosis in hescs. |
2023-06-26 |
2023-08-14 |
human |
| Yiyang Sun, Lingling Zhang, Zhuoqing Fang, Dingyu Liu, Min Shao, Yujie Liu, Bing Liao, Ying Ji. PRPF8 controls alternative splicing of PIRH2 to modulate the p53 pathway and survival of human ESCs. Journal of cellular physiology. 2023-06-26. PMID:37357506. |
strikingly, silencing of p53 rescues prpf8 kd-induced apoptosis, indicating that prpf8 kd triggers hesc apoptosis through activating the p53 pathway. |
2023-06-26 |
2023-08-14 |
human |
| Masumeh Sanaei, Fraidoon Kavoos. Effect of Zebularine on Apoptotic Pathways in Hepatocellular Carcinoma Cell Lines. International journal of preventive medicine. vol 14. 2023-06-23. PMID:37351028. |
this study was assigned to assess the effect of zebularine on intrinsic and extrinsic pathways, dnat 1, 3a, and 3b, p21, and p53, viability, and apoptosis in hepatocellular carcinoma (hcc) cell lines. |
2023-06-23 |
2023-08-14 |
human |
| Roba Abukwaik, Elias Vera-Siguenza, Daniel A Tennant, Fabian Spil. Interplay of p53 and XIAP protein dynamics orchestrates cell fate in response to chemotherapy. Journal of theoretical biology. 2023-06-22. PMID:37348784. |
two critical factors play a role in chemoresistance: the p53 tumour suppressor gene and the x-linked inhibitor of apoptosis (xiap). |
2023-06-22 |
2023-08-14 |
Not clear |
| Roba Abukwaik, Elias Vera-Siguenza, Daniel A Tennant, Fabian Spil. Interplay of p53 and XIAP protein dynamics orchestrates cell fate in response to chemotherapy. Journal of theoretical biology. 2023-06-22. PMID:37348784. |
this study introduces a mathematical model characterising the apoptosis pathway activation by p53 before and after mitochondrial outer membrane permeabilisation upon treatment with the chemotherapy doxorubicin (dox). |
2023-06-22 |
2023-08-14 |
Not clear |
| Roba Abukwaik, Elias Vera-Siguenza, Daniel A Tennant, Fabian Spil. Interplay of p53 and XIAP protein dynamics orchestrates cell fate in response to chemotherapy. Journal of theoretical biology. 2023-06-22. PMID:37348784. |
consequently, the model predicts that failure to activate apoptosis in some cancer cells expressing wild-type p53 might be due to heterogeneity between cells in upregulating the xiap protein, rather than due to the p53 protein concentration. |
2023-06-22 |
2023-08-14 |
Not clear |
| Haili Li, Ze Zhang, Huixin Li, Xinyu Pan, Yue Wan. New Insights into the Roles of p53 in Central Nervous System Diseases. The international journal of neuropsychopharmacology. 2023-06-20. PMID:37338366. |
in addition to its role in tumors, p53 has a widespread expression in the brain and participates in most cell processes, such as dendrite formation, oxidative stress, apoptosis, autophagy, dna repair and cell cycle arrest. |
2023-06-20 |
2023-08-14 |
Not clear |
| Shuai Wang, Jie Bai, Yilin Che, Weikun Qu, Jing L. Fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through USP22/Sirt 1. Frontiers in pharmacology. vol 14. 2023-06-16. PMID:37324479. |
fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through usp22/sirt 1. |
2023-06-16 |
2023-08-14 |
Not clear |
| Aiqing Ma, Xianhua Da. The mechanism accounting for DNA damage strength modulation of p53 dynamical properties. Journal of bioinformatics and computational biology. 2023-06-16. PMID:37325863. |
in addition, the pulse interval is negatively correlated with apoptosis; the greater the damage strength, the smaller the pulse interval, the faster the p53 accumulation rate, and the cells are more susceptible to apoptosis. |
2023-06-16 |
2023-08-14 |
Not clear |
| Haixia Ji, Ou Qiao, Yi Zhang, Wenzhe Wang, Xiaoyin Han, Xinyu Zhang, Changxiao Liu, Wenyuan Ga. Dual targeting of wild-type p53 and gut microbiota by Magnolol represses key metabolic process and kills CRC cells. Phytotherapy research : PTR. 2023-06-16. PMID:37326338. |
herein, we illustrate that the tumor repressor p53 mediate magnolol (mag) triggers colon cancer cell apoptosis. |
2023-06-16 |
2023-08-14 |
Not clear |
| A Frega, C Gentili, S Proietti, E Lepore, V Unfer, A Fus. Epigallocatechin gallate, folic acid, vitamin B12, and hyaluronic acid significantly increase apoptosis and p53 expression in HeLa cells. European review for medical and pharmacological sciences. vol 27. issue 11. 2023-06-15. PMID:37318498. |
epigallocatechin gallate, folic acid, vitamin b12, and hyaluronic acid significantly increase apoptosis and p53 expression in hela cells. |
2023-06-15 |
2023-08-14 |
human |
| Weiwei Lv, Haotian Gu, Defu He, Zhiquan Liu, Chunxia Yao, Weiwei Huang, Quan Yuan, Wenzong Zho. Polystyrene nanospheres-induced hepatotoxicity in swamp eel (Monopterus albus): From biochemical, pathological and transcriptomic perspectives. The Science of the total environment. 2023-06-15. PMID:37321506. |
moreover, signaling cascades keap1-nrf2, p53 and ppar were either substantially initiated or dysregulated to orchestrate ps-nps hepatotoxicity featuring oxidative damage, hepatocyte apoptosis and lipid steatosis. |
2023-06-15 |
2023-08-14 |
Not clear |
| Mayuri Khot, Anika Sood, Kamatham Pushpa Tryphena, Poojitha Pinjala, Saurabh Srivastava, Shashi Bala Singh, Dharmendra Kumar Khatr. Dimethyl fumarate ameliorates Parkinsonian pathology by modulating autophagy and apoptosis via Nrf2-TIGAR-LAMP2/Cathepsin D axis. Brain research. 2023-06-14. PMID:37315723. |
dmf promoted autophagosome formation and inhibited apoptosis by removing the inhibitory effect of p53 on tigar. |
2023-06-14 |
2023-08-14 |
mouse |
| Aylin Balcı Özyurt, Pınar Erkekoğlu, Naciye Dilara Zeybek, Ali Aşcı, Ünzile Yaman, Ofcan Oflaz, Murat Kızılgün, Evin İşcan, Tuğçe Batur, Mehmet Öztürk, Belma Koçer-Gümüşe. Toxic effects of Aroclor 1254 on rat liver and modifying roles of selenium. International journal of environmental health research. 2023-06-13. PMID:37309736. |
histopathology, oxidant/antioxidant balance, apoptosis and cell cycle proteins (p53, p21) in liver were evaluated. |
2023-06-13 |
2023-08-14 |
human |
| Liangzi Cao, Hao Li, Xiaofang Liu, Yubang Wang, Bowen Zheng, Chengzhong Xing, Naijin Zhang, Jingwei Li. Expression and regulatory network of E3 ubiquitin ligase NEDD4 family in cancers. BMC cancer. vol 23. issue 1. 2023-06-08. PMID:37291499. |
nedd4 family members interacted proteins were enriched in various pathways including p53, akt, apoptosis and autophagy, which were confirmed by further western blot and flow cytometric analysis in a549 and h1299 lung cancer cells. |
2023-06-08 |
2023-08-14 |
Not clear |