| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fenyong Yao, Shisheng Huang, Jiahui Liu, Chunhua Tan, Mengqi Xu, Dengkui Wang, Maoqing Huang, Yiyao Zhu, Xingxu Huang, Shuijin H. Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell death & disease. vol 14. issue 8. 2023-08-23. PMID:37612280. |
although they remain proliferative, ectopic progenitors, as well as progenitors in the vz, exhibit prolonged mitosis, p53 upregulation and cell apoptosis, leading to reduced neuron production, neuronal loss and microcephaly. |
2023-08-23 |
2023-09-07 |
mouse |
| Jacyara Maria Brito Macedo, Amanda Lima Silva, Amanda Chaves Pinto, Leandro Ferreira Lopes Landeira, Elyzabeth Avvad Portari, Cintia Barros Santos-Rebouças, Evandro Mendes Klum. TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus. Advances in rheumatology (London, England). vol 63. issue 1. 2023-08-22. PMID:37605254. |
the p53 and p21 proteins are important regulators of cell cycle and apoptosis and may contribute to autoimmune diseases, such as systemic lupus erythematosus (sle). |
2023-08-22 |
2023-09-07 |
Not clear |
| Seth Harris, Kyoungtae Ki. Apoptotic pathway protein expression variance in metal oxide and quantum dot treated HeLa cells. microPublication biology. vol 2023. 2023-08-21. PMID:37602282. |
western blot techniques were used to measure protein expression of phosphorylated p53 (ser15), puma, and p21 which are involved in signal transduction of apoptosis. |
2023-08-21 |
2023-09-07 |
Not clear |
| Lindsey Carlsen, Shengliang Zhang, Xiaobing Tian, Arielle De La Cruz, Andrew George, Taylor E Arnoff, Wafik S El-Deir. The role of p53 in anti-tumor immunity and response to immunotherapy. Frontiers in molecular biosciences. vol 10. 2023-08-21. PMID:37602328. |
p53 regulates hundreds of target genes that induce various cell fates including apoptosis, cell cycle arrest, and dna damage repair. |
2023-08-21 |
2023-09-07 |
human |
| Vahid Asghariazar, Mohammad Amini, Zahra Pirdel, Roghayeh Fekri, Asadollah Asadi, Kazem Nejati-Koshki, Behzad Baradaran, Yasin Panah. The Schiff base hydrazine copper(II) complexes induce apoptosis by P53 overexpression and prevent cell migration through protease-independent pathways. Medical oncology (Northwood, London, England). vol 40. issue 9. 2023-08-18. PMID:37594547. |
the schiff base hydrazine copper(ii) complexes induce apoptosis by p53 overexpression and prevent cell migration through protease-independent pathways. |
2023-08-18 |
2023-09-07 |
Not clear |
| Hongnan Li, Weidong Lin, Guangzhi Zhang, Runsheng Liu, Minghai Qu, Jiayang Zhang, Xuekun Xin. BMSC-exosomes miR-25-3p Regulates the p53 Signaling Pathway Through PTEN to Inhibit Cell Apoptosis and Ameliorate Liver Ischemia‒reperfusion Injury. Stem cell reviews and reports. 2023-08-18. PMID:37594613. |
bmsc-exosomes mir-25-3p regulates the p53 signaling pathway through pten to inhibit cell apoptosis and ameliorate liver ischemia‒reperfusion injury. |
2023-08-18 |
2023-09-07 |
Not clear |
| Shuqian Hu, Hui Xu, Conghua Xie, Yan Meng, Xiaojuan X. Inhibition of human cervical cancer development through p53-dependent pathways induced by the specified triple helical β-glucan. International journal of biological macromolecules. 2023-08-16. PMID:37586625. |
from the in vitro data, the potential mechanism of anti-cervical cancer was preliminarily revealed as follows: lnt was firstly recognized by the human cervical cancer cell line of hela and induced cell proliferation inhibition through p21 and apoptosis via a mitochondrion-dependent pathway by targeting the tumor suppressor of p53, indicated by an increase in reactive oxygen species (ros) generation and a loss of mitochondrial membrane potential (Δψ |
2023-08-16 |
2023-09-07 |
human |
| Nabanita Mukherjee, Debmalya Bhunia, Prabir Kumar Garai, Prasenjit Mondal, Surajit Barman, Surajit Ghos. Designed novel nuclear localizing anticancer peptide targets p53 negative regulator MDM2 protein. Journal of peptide science : an official publication of the European Peptide Society. 2023-08-15. PMID:37580909. |
modulation of mdm2-p53 interaction via fabrication of an mdm2-interacting peptide could be a useful strategy to inhibit subsequent proteasomal degradation of p53 and initiation of p53 signaling leading to the initiation of p53-mediated apoptosis of tumor cells. |
2023-08-15 |
2023-09-07 |
Not clear |
| Johannes P Suwita, Calvin K Voong, Elina Ly, James A Goodrich, Jennifer F Kuge. Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements. PloS one. vol 18. issue 8. 2023-08-15. PMID:37582100. |
the transcriptional activator p53 is a tumor suppressor protein that controls cellular pathways important for cell fate decisions, including cell cycle arrest, senescence, and apoptosis. |
2023-08-15 |
2023-09-07 |
human |
| Aranka Brockmueller, Constanze Buhrmann, Parviz Shayan, Mehdi Shakibae. Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment. Frontiers in immunology. vol 14. 2023-08-14. PMID:37575245. |
resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and sirt-1 in the crc tumor microenvironment. |
2023-08-14 |
2023-08-16 |
Not clear |
| Shin Kim, Dong Eun Kim, Hyunsu Kang, Victor Sukbong Hong, Jieun Jeon, Jinho Lee, Ki-Suk Kim, Jong-Wook Par. KMU-191 Induces Apoptosis in Human Clear Cell Renal Cell Carcinoma Caki Cells Through Modulation of Bcl-xL, Mcl-1 (L), c-FLIP (L), and p53 Proteins. Journal of Cancer. vol 14. issue 12. 2023-08-14. PMID:37576393. |
kmu-191 induces apoptosis in human clear cell renal cell carcinoma caki cells through modulation of bcl-xl, mcl-1 (l), c-flip (l), and p53 proteins. |
2023-08-14 |
2023-08-16 |
human |
| Ian C Lock, Nathan H Leisenring, Warren Floyd, Eric S Xu, Lixia Luo, Yan Ma, Erin C Mansell, Diana M Cardona, Chang-Lung Lee, David G Kirsc. Mis-splicing Drives Loss of Function of p53 bioRxiv : the preprint server for biology. 2023-08-14. PMID:37577531. |
challenging this dogma, mouse models have revealed that p53 driven apoptosis and cell cycle arrest are dispensable for tumor suppression. |
2023-08-14 |
2023-08-16 |
mouse |
| Adriana Cortés, Javier Marqués, Álvaro Pejenaute, Elena Ainzúa, Eduardo Ansorena, Gloria Abizanda, Felipe Prósper, Carlos de Miguel, Guillermo Zalb. Endothelial NOX5 overexpression induces changes in the cardiac gene profile: potential impact in myocardial infarction? Journal of physiology and biochemistry. 2023-08-11. PMID:37566320. |
we found many alterations in the mrna expression of components involved in cardiac fibrosis as collagen type i or tgf-β and in key players of cardiac apoptosis such as akt, bcl-2, or p53. |
2023-08-11 |
2023-08-16 |
mouse |
| Mazin Aboobaida Abdalla Abdelaziz, Vinod Kumar Nelson, Murali Kumarasamy, Ramalingam Perama. Anticancer effect of polyphenolic acid enriched fractions from Grewia bracteata Roth on tumor cells and their p53 gene independent ROS mediated apoptosis in colon cancer cells. Toxicon : official journal of the International Society on Toxinology. 2023-08-11. PMID:37567418. |
anticancer effect of polyphenolic acid enriched fractions from grewia bracteata roth on tumor cells and their p53 gene independent ros mediated apoptosis in colon cancer cells. |
2023-08-11 |
2023-08-16 |
Not clear |
| Zhihui Dou, Xuetian Zhang, Wei Su, Taotao Zhang, Fei Ye, Dapeng Zhao, Xiaohua Chen, Qiang Li, Hong Zhang, Cuixia D. Indisulam exerts anticancer effects via modulation of transcription, translation and alternative splicing on human cervical cancer cells. American journal of cancer research. vol 13. issue 7. 2023-08-10. PMID:37559979. |
indisulam increased tap73 expression and triggered mitochondrial apoptosis independent of p53 status in hela cells. |
2023-08-10 |
2023-08-16 |
human |
| Xiangyu Zeng, Fei Zhao, Jie Jia, Xianxiong Ma, Qi Jiang, Ruizhi Zhang, Chengguo Li, Tao Wang, Weizhen Liu, Yalan Hao, Kaixiong Tao, Zhenkun Lou, Peng Zhan. Targeting BCL6 in gastrointestinal stromal tumor promotes p53-mediated apoptosis to enhance the antitumor activity of imatinib. Cancer research. 2023-08-09. PMID:37556508. |
the reduction in p53 subsequently attenuated cell apoptosis and promoted tolerance of gist cells to im. |
2023-08-09 |
2023-08-16 |
Not clear |
| Kai Zhang, Jianzhao Liao, Zhuoying Hu, Quanwei Li, Lianmei Hu, Jianying Guo, Ying Li, Hui Zhang, Jiaqiang Pan, Zhaoxin Tan. Mitochondria-mediated apoptosis and endoplasmic reticulum stress are involved in the toxicity induced by copper in the porcine spleen. Environmental science and pollution research international. 2023-08-05. PMID:37542695. |
furthermore, cu exposure could induce apoptosis, as demonstrated by the increased expression level of related proteins and genes bak, bax, caspase-3, p53, and cytc. |
2023-08-05 |
2023-08-14 |
Not clear |
| Mahtab Shahriari Felordi, Mehdi Alikhani, Zahra Farzaneh, Mahmoud Alipour Choshali, Marzieh Ebrahimi, Hamidreza Aboulkheyr Es, Abbas Piryaei, Mustapha Najimi, Massoud Vosoug. (-)-Epigallocatechin-3-gallate induced apoptosis by dissociation of c-FLIP/Ku70 complex in gastric cancer cells. Journal of cellular and molecular medicine. 2023-08-04. PMID:37537749. |
egcg induced apoptosis in mkn-45 cells with substantial up-regulation of p53 and p21, down-regulation of c-myc and cyclin d1 as well as cell cycle arrest in s and g2/m check points. |
2023-08-04 |
2023-08-14 |
Not clear |
| Fei Wang, Ali Bashiri Dezfouli, Mohammad Khosravi, Wolfgang Sievert, Stefan Stangl, Melissa Schwab, Zhiyuan Wu, Katja Steiger, Hu Ma, Gabriele Multhof. Cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal cancer cells involves p53 and Hsp70. Cell death discovery. vol 9. issue 1. 2023-08-04. PMID:37542074. |
cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal cancer cells involves p53 and hsp70. |
2023-08-04 |
2023-08-14 |
Not clear |
| Fei Wang, Ali Bashiri Dezfouli, Mohammad Khosravi, Wolfgang Sievert, Stefan Stangl, Melissa Schwab, Zhiyuan Wu, Katja Steiger, Hu Ma, Gabriele Multhof. Cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal cancer cells involves p53 and Hsp70. Cell death discovery. vol 9. issue 1. 2023-08-04. PMID:37542074. |
this study provides new insights into the potential mechanisms of cbd-induced mutual antagonism of apoptosis and macroautophagy using wild type (hct116 p53wt, ls174t p53wt), knockout (hct116 p53 |
2023-08-04 |
2023-08-14 |
Not clear |