| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dunyun Shi, Yun Xu, Xin Du, Xuhong Chen, Xiaoli Zhang, Jin Lou, Ming Li, Jiacai Zhu. Co-treatment of THP-1 cells with naringenin and curcumin induces cell cycle arrest and apoptosis via numerous pathways. Molecular medicine reports. vol 12. issue 6. 2016-09-22. PMID:26496980. |
these results indicated that naringenin may enhance curcumin‑induced apoptosis through inhibiting the akt and erk pathways, and promoting the jnk and p53 pathways. |
2016-09-22 |
2023-08-13 |
Not clear |
| Alexander V Sirotkin, Diana Kardošová, Saleh Hamad Alwasel, Abdel Halim Harrat. Neuropeptide Y directly affects ovarian cell proliferation and apoptosis. Reproductive biology. vol 15. issue 4. 2016-09-22. PMID:26679167. |
npy inhibited proliferation as well as promoted apoptosis and accumulation of p53 in the cells. |
2016-09-22 |
2023-08-13 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad Zamani Rarani, Ali Valiani, Mohsen Mahmoudie. The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. Research in pharmaceutical sciences. vol 11. issue 4. 2016-09-21. PMID:27651810. |
the effect of adenosine a1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in mcf-7 breast cancer cell line. |
2016-09-21 |
2023-08-13 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad Zamani Rarani, Ali Valiani, Mohsen Mahmoudie. The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. Research in pharmaceutical sciences. vol 11. issue 4. 2016-09-21. PMID:27651810. |
the aim of this study was to investigate the correlation between a1 receptor and either cell apoptosis or proliferation and also to recognize the relationship between this receptor and p53 and the expression of caspases 3, 8 and 9 in mcf-7 cell line. |
2016-09-21 |
2023-08-13 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad Zamani Rarani, Ali Valiani, Mohsen Mahmoudie. The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. Research in pharmaceutical sciences. vol 11. issue 4. 2016-09-21. PMID:27651810. |
mcf-7 cells were treated intermittently with a1 receptor agonist n6-cyclopentyladenosine (cpa) and a1 receptor antagonist 1,3-dipropyl-8-cyclopentylxanthine (dpcpx) in different times to measure the expression of p53, caspase 3, 8 and 9 besides apoptosis and survival rate. |
2016-09-21 |
2023-08-13 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad Zamani Rarani, Ali Valiani, Mohsen Mahmoudie. The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. Research in pharmaceutical sciences. vol 11. issue 4. 2016-09-21. PMID:27651810. |
our findings indicated that dpcpx significantly induced apoptosis in mcf-7 cells while the cell viability was reduced specially 72 h after the treatment and the expression of p53 gene and caspase expressions was dramatically up-regulated. |
2016-09-21 |
2023-08-13 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad Zamani Rarani, Ali Valiani, Mohsen Mahmoudie. The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. Research in pharmaceutical sciences. vol 11. issue 4. 2016-09-21. PMID:27651810. |
furthermore, dpcpx induced p53 and caspase 3, 8 and 9 expressions that consequently promotes the cell apoptosis in mcf-7 cells. |
2016-09-21 |
2023-08-13 |
Not clear |
| Zhaoyue He, Massimiliano Agostini, He Liu, Gerry Melino, Hans-Uwe Simo. p73 regulates basal and starvation-induced liver metabolism in vivo. Oncotarget. vol 6. issue 32. 2016-09-21. PMID:26375672. |
as a member of the p53 gene family, p73 regulates cell cycle arrest, apoptosis, neurogenesis, immunity and inflammation. |
2016-09-21 |
2023-08-13 |
mouse |
| Rong Yin, Lin Yuan, Lili Ping, Liyuan H. Neonatal bronchopulmonary dysplasia increases neuronal apoptosis in the hippocampus through the HIF-1α and p53 pathways. Respiratory physiology & neurobiology. vol 220. 2016-09-21. PMID:26431790. |
neonatal bronchopulmonary dysplasia increases neuronal apoptosis in the hippocampus through the hif-1α and p53 pathways. |
2016-09-21 |
2023-08-13 |
rat |
| Rong Yin, Lin Yuan, Lili Ping, Liyuan H. Neonatal bronchopulmonary dysplasia increases neuronal apoptosis in the hippocampus through the HIF-1α and p53 pathways. Respiratory physiology & neurobiology. vol 220. 2016-09-21. PMID:26431790. |
these findings suggested that neonatal bpd caused impaired cognitive function and neuron apoptosis in hippocampus via p53 and hif-1α. |
2016-09-21 |
2023-08-13 |
rat |
| Ming Liu, Dan Wang, Ning L. Che-1 gene silencing induces osteosarcoma cell apoptosis by inhibiting mutant p53 expression. Biochemical and biophysical research communications. vol 473. issue 1. 2016-09-21. PMID:27012205. |
che-1 gene silencing induces osteosarcoma cell apoptosis by inhibiting mutant p53 expression. |
2016-09-21 |
2023-08-13 |
Not clear |
| Ming Liu, Dan Wang, Ning L. Che-1 gene silencing induces osteosarcoma cell apoptosis by inhibiting mutant p53 expression. Biochemical and biophysical research communications. vol 473. issue 1. 2016-09-21. PMID:27012205. |
notably, our study showed that the loss of che-1 inhibits proliferation and promotes apoptosis in mg-63 cells by decreasing the level of mutant p53. |
2016-09-21 |
2023-08-13 |
Not clear |
| Roger Ramcharan, Tamara Aleksic, Wilfride Petnga Kamdoum, Shan Gao, Sophia X Pfister, Jordan Tanner, Esther Bridges, Ruth Asher, Amanda J Watson, Geoffrey P Margison, Mick Woodcock, Emmanouela Repapi, Ji-Liang Li, Mark R Middleton, Valentine M Macaula. IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide. Oncotarget. vol 6. issue 37. 2016-09-20. PMID:26497996. |
clinically relevant sequential (tmz → igf-1ri) treatment was tested in mice bearing a375m (v600e braf, wild-type p53) melanoma xenografts, achieving peak plasma/tumor igf-1ri levels comparable to clinical cmax, and inducing extensive intratumoral apoptosis. |
2016-09-20 |
2023-08-13 |
mouse |
| Xiaolin Zhang, Hao Y. Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression. Iranian journal of pharmaceutical research : IJPR. vol 15. issue 2. 2016-09-19. PMID:27642320. |
matrine inhibits diethylnitrosamine-induced hcc proliferation in rats through inducing apoptosis via p53, bax-dependent caspase-3 activation pathway and down-regulating mlck overexpression. |
2016-09-19 |
2023-08-13 |
rat |
| Xiaolin Zhang, Hao Y. Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression. Iranian journal of pharmaceutical research : IJPR. vol 15. issue 2. 2016-09-19. PMID:27642320. |
western blot analysis of p53, bax, cleaved caspase-3 and myosin light chain kinase (mlck) revealed that matrine induced tumor cell apoptosis by controlling anoikis. |
2016-09-19 |
2023-08-13 |
rat |
| Xiaolin Zhang, Hao Y. Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression. Iranian journal of pharmaceutical research : IJPR. vol 15. issue 2. 2016-09-19. PMID:27642320. |
our results suggest that matrine can inhibit the proliferation of hcc cells through inducing tumor cell apoptosis via activation of the p53 pathway and inhibition of mlck overexpression. |
2016-09-19 |
2023-08-13 |
rat |
| Shruti Chowdhari, Neeru Sain. Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes. Cellular signalling. vol 28. issue 1. 2016-09-19. PMID:26518362. |
gene expression profiling reveals the role of rig1 like receptor signaling in p53 dependent apoptosis induced by puva in keratinocytes. |
2016-09-19 |
2023-08-13 |
Not clear |
| Shruti Chowdhari, Neeru Sain. Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes. Cellular signalling. vol 28. issue 1. 2016-09-19. PMID:26518362. |
microarray analysis revealed 1932 differentially expressed gene and their insilico analysis revealed retinoic acid inducible gene-i (rig-1) signaling, apoptosis and p53 pathway to be associated with puva induced effects. |
2016-09-19 |
2023-08-13 |
Not clear |
| E Lasorsa, M Smonksey, J S Kirk, S Rosario, F J Hernandez-Ilizaliturri, L Elli. Mitochondrial protection impairs BET bromodomain inhibitor-mediated cell death and provides rationale for combination therapeutic strategies. Cell death & disease. vol 6. 2016-09-19. PMID:26658189. |
genetic dissection using eμ-myc b-cell lymphoma compound mutants demonstrated that i-bet762-induced apoptosis does not require the p53 pathway. |
2016-09-19 |
2023-08-13 |
human |
| W Wu, C Xu, X Ling, C Fan, B P Buckley, M V Chernov, L Ellis, F Li, I G Muñoz, X Wan. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells. Cell death & disease. vol 6. 2016-09-19. PMID:26720344. |
in contrast to nutlin3a, mmri64 only induces the expression of pro-apoptotic gene puma (p53 upregulated modulator of apoptosis) with minimal induction of growth-arresting gene p21. |
2016-09-19 |
2023-08-13 |
mouse |