| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonella Muscella, Carla Vetrugno, Luca Giulio Cossa, Giovanna Antonaci, Amilcare Barca, Sandra Angelica De Pascali, Francesco Paolo Fanizzi, Santo Marsigliant. Apoptosis by [Pt(O,O'-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma. PloS one. vol 12. issue 7. 2017-10-03. PMID:28704484. |
apoptosis by [pt(o,o'-acac)(γ-acac)(dms)] requires pkc-δ mediated p53 activation in malignant pleural mesothelioma. |
2017-10-03 |
2023-08-13 |
mouse |
| Mariette Matondo, Marlène Marcellin, Karima Chaoui, Marie-Pierre Bousquet-Dubouch, Anne Gonzalez-de-Peredo, Bernard Monsarrat, Odile Burlet-Schilt. Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large-scale and targeted quantitative proteomics. Proteomics. vol 17. issue 7. 2017-10-02. PMID:27709814. |
despite the broad range of proteins known to be affected by proteasome inhibition, such as heat shock (hsp) and cell cycle proteins, our analysis identified new differentially regulated proteins, including il-32, morf family mortality factors and apoptosis inducing factor siva, a target of p53. |
2017-10-02 |
2023-08-13 |
human |
| Neeharika Verma, Sunil K Mann. Advanced glycation end products (AGE) potentiates cell death in p53 negative cells via upregulaion of NF-kappa B and impairment of autophagy. Journal of cellular physiology. vol 232. issue 12. 2017-10-02. PMID:28128446. |
we have identified cross talk between autophagy and apoptosis upon age stimulation, specifically in p53 negative cells. |
2017-10-02 |
2023-08-13 |
Not clear |
| Charlotte Thieury, Nicolas Lebouvier, Rémy Le Guével, Yann Barguil, Gaëtan Herbette, Cyril Antheaume, Edouard Hnawia, Yoshinori Asakawa, Mohammed Nour, Thierry Guillaudeu. Mechanisms of action and structure-activity relationships of cytotoxic flavokawain derivatives. Bioorganic & medicinal chemistry. vol 25. issue 6. 2017-10-02. PMID:28214231. |
fkd induced a g1/s arrest on p53 wild-type cells and an m arrest on p53 mutant-type, via the up-regulation of p21 and cyclin b1 proteins, followed by apoptosis. |
2017-10-02 |
2023-08-13 |
Not clear |
| Xiaojie Huang, Tianming Lian, Xiaoqian Guan, Bin Liu, Siyuan Hao, Jingjing Zhang, Shiting Bao, Xiaoyu Tan, Runzhi Zh. Dihydromyricetin Reduces TGF-β Via P53 Activation-dependent Mechanism in Hepatocellular Carcinoma HepG2 Cells. Protein and peptide letters. vol 24. issue 5. 2017-10-02. PMID:28240161. |
these findings defined and supported a novel mechanism that dhm could induce cell apoptosis by reducing tgf-β via p53 signal pathway in hepg2 cells. |
2017-10-02 |
2023-08-13 |
human |
| Bin Liu, Miaomiao Zhang, Shuna Liu, Jie Ying, Jingjing Zhang, Hiroshi Kurihara, Weiqiang Zheng, Rong-Rong He, Runzhi Zh. Diosmetin, a Potential p53 Activator, Performs Anticancer Effect by Regulating Cell Cycling and Cell Proliferation in HepG2 Cells. Protein and peptide letters. vol 24. issue 5. 2017-10-02. PMID:28240165. |
meanwhile, dios-induced liver cancer cell apoptosis was related with the p53 activation. |
2017-10-02 |
2023-08-13 |
Not clear |
| Bin Liu, Miaomiao Zhang, Shuna Liu, Jie Ying, Jingjing Zhang, Hiroshi Kurihara, Weiqiang Zheng, Rong-Rong He, Runzhi Zh. Diosmetin, a Potential p53 Activator, Performs Anticancer Effect by Regulating Cell Cycling and Cell Proliferation in HepG2 Cells. Protein and peptide letters. vol 24. issue 5. 2017-10-02. PMID:28240165. |
by activating p53, dios exerts anticancer effects by inducing cell cycle arrest and apoptosis in hepg2 cells. |
2017-10-02 |
2023-08-13 |
Not clear |
| Bin Liu, Kaiqiao Jia, Yu Yang, Siyuan Hao, Caijie Lu, Fengming Xu, Dehui Feng, Runzhi Zh. Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells. Protein and peptide letters. vol 24. issue 5. 2017-10-02. PMID:28245756. |
diosmetin induces cell apoptosis by regulating cyp1a1/cyp1a2 due to p53 activation in hepg2 cells. |
2017-10-02 |
2023-08-13 |
human |
| Bin Liu, Kaiqiao Jia, Yu Yang, Siyuan Hao, Caijie Lu, Fengming Xu, Dehui Feng, Runzhi Zh. Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells. Protein and peptide letters. vol 24. issue 5. 2017-10-02. PMID:28245756. |
diosinduced cell apoptosis could be reversed due to p53 blockade and the cellular p53 and cyp1a1/cyp1a2 proteins levels were examined. |
2017-10-02 |
2023-08-13 |
human |
| Ananga Ghosh, Amrita Sengupta, Guru Pavan Kumar Seerapu, Ali Nakhi, E V Venkat Shivaji Ramarao, Navneet Bung, Gopalakrishnan Bulusu, Manojit Pal, Devyani Halda. A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53. Biochemical and biophysical research communications. vol 488. issue 3. 2017-10-02. PMID:28526414. |
a novel sirt1 inhibitor, 4bb induces apoptosis in hct116 human colon carcinoma cells partially by activating p53. |
2017-10-02 |
2023-08-13 |
human |
| Ananga Ghosh, Amrita Sengupta, Guru Pavan Kumar Seerapu, Ali Nakhi, E V Venkat Shivaji Ramarao, Navneet Bung, Gopalakrishnan Bulusu, Manojit Pal, Devyani Halda. A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53. Biochemical and biophysical research communications. vol 488. issue 3. 2017-10-02. PMID:28526414. |
further, 4bb treatment increased p53 acetylation, bax expression and induced caspase 3 cleavage suggesting that the death of hct116 colon cancer cells occur through intrinsic pathway of apoptosis. |
2017-10-02 |
2023-08-13 |
human |
| Ananga Ghosh, Amrita Sengupta, Guru Pavan Kumar Seerapu, Ali Nakhi, E V Venkat Shivaji Ramarao, Navneet Bung, Gopalakrishnan Bulusu, Manojit Pal, Devyani Halda. A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53. Biochemical and biophysical research communications. vol 488. issue 3. 2017-10-02. PMID:28526414. |
overall, our results presents 4bb as a new class of human sirt1 inhibitor and suggest that inhibition of sirt1 by 4bb induces apoptosis of colon cancer cells at least in part via activating p53 by preventing p53 deacetylation, increasing bax expression and inducing caspases. |
2017-10-02 |
2023-08-13 |
human |
| Ritam Chatterjee, Shubhangi Gupta, Sujata La. Hematopathological alterations of major tumor suppressor cascade, vital cell cycle inhibitors and hematopoietic niche components in experimental myelodysplasia. Chemico-biological interactions. vol 273. 2017-10-02. PMID:28549617. |
elevated cellular apoptosis and rise in the blast burden were also found to be associated with the p53 expression dependent collapsing of mitochondrial membrane potential and upregulation of tie-2 respectively. |
2017-10-02 |
2023-08-13 |
mouse |
| Suerialoasan Navanesan, Norhanom Abdul Wahab, Sugumaran Manickam, Yuen Lin Cheow, Kae Shin Si. Intrinsic capabilities of Leptospermum javanicum in inducing apoptosis and suppressing the metastatic potential of human lung carcinoma cells. Chemico-biological interactions. vol 273. 2017-10-02. PMID:28578903. |
the results pointed towards the induction of apoptosis as a result of increasing doses of ba, regardless of the p53 status in both cell lines. |
2017-10-02 |
2023-08-13 |
human |
| Aubrey Converse, Chenan Zhang, Peter Thoma. Membrane Androgen Receptor ZIP9 Induces Croaker Ovarian Cell Apoptosis via Stimulatory G Protein Alpha Subunit and MAP Kinase Signaling. Endocrinology. vol 158. issue 9. 2017-10-02. PMID:28633436. |
testosterone treatment of croaker g/t cells increased intracellular zinc levels, mitogen-activated protein (map) kinase activity, caspase 3 activity, messenger rna levels of proapoptotic members bax, p53, and c-jun n-terminal kinase, and the incidence of apoptosis, similar to findings in mammalian cancer cells, but also increased cyclic adenosine monophosphate concentrations. |
2017-10-02 |
2023-08-13 |
human |
| Lianmin Bao, Hua Diao, Nian Dong, Xiaoqiong Su, Bingbin Wang, Qiongya Mo, Heguo Yu, Xiangdong Wang, Chengshui Che. Histone deacetylase inhibitor induces cell apoptosis and cycle arrest in lung cancer cells via mitochondrial injury and p53 up-acetylation. Cell biology and toxicology. vol 32. issue 6. 2017-09-29. PMID:27423454. |
histone deacetylase inhibitor induces cell apoptosis and cycle arrest in lung cancer cells via mitochondrial injury and p53 up-acetylation. |
2017-09-29 |
2023-08-13 |
Not clear |
| M Fische. Census and evaluation of p53 target genes. Oncogene. vol 36. issue 28. 2017-09-29. PMID:28288132. |
here, p53 target genes have been evaluated based on the meta-analysis data, and the results show that high-confidence p53 target genes are involved in multiple cellular responses, including cell cycle arrest, dna repair, apoptosis, metabolism, autophagy, mrna translation and feedback mechanisms. |
2017-09-29 |
2023-08-13 |
Not clear |
| Shunsheng Zheng, Xin Yu Koh, Hui Chin Goh, Siti Aishah B Rahmat, Le-Ann Hwang, David P Lan. Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity. Cancer research. vol 77. issue 16. 2017-09-29. PMID:28655792. |
in this study, we discovered that c646, a reversible p300 inhibitor, downregulates p53 transcription and selectively protects noncancerous cells from p53-dependent apoptosis. |
2017-09-29 |
2023-08-13 |
mouse |
| Yelisetti Uma Mahesh, Henderson Rose Winnie Gibence, Sisinthy Shivaji, Brahmasani Sambasiva Ra. Effect of different cryo-devices on in vitro maturation and development of vitrified-warmed immature buffalo oocytes. Cryobiology. vol 75. 2017-09-27. PMID:28093199. |
the expression of oocyte secreting factors and their receptors (gdf9, bmp15, bmpr2, tgfbr1) and apoptosis related genes (bcl2, bax, p53, c-myc) were compared in vitrified-warmed oocytes after in vitro maturation. |
2017-09-27 |
2023-08-13 |
Not clear |
| Xingwen Wang, Yiwei Cheng, YiFu Zhu, Huayi Li, Wenjie Ge, Xiaoliang Wu, Kunming Zhao, Jinyang Yuan, Zhenglin Li, Shijian Jiang, Zhengbin Han, Qinghua Jiang, Qiong Wu, Tao Liu, Cheng Zhang, Miao Yu, Ying H. Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation. International journal of cancer. vol 141. issue 7. 2017-09-27. PMID:28656647. |
here, we report, for the first time, that apoptosis stimulating of p53 protein 1 (aspp1) was remarkably downregulated at both mrna (about 3.9-fold) and protein (about 4.9-fold) levels in ccrcc human specimens in comparison with the paired normal controls. |
2017-09-27 |
2023-08-13 |
human |