| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samar K Kassim, Laila Seada, Samer Ibrahi. Human Papillomavirus High-risk Genotypes: Relationship to Apoptosis and p53 Expression in Egyptian Patients with Laryngeal Carcinoma. Cancer genomics & proteomics. vol 1. issue 2. 2019-08-09. PMID:31394679. |
human papillomavirus high-risk genotypes: relationship to apoptosis and p53 expression in egyptian patients with laryngeal carcinoma. |
2019-08-09 |
2023-08-13 |
human |
| Samar K Kassim, Laila Seada, Samer Ibrahi. Human Papillomavirus High-risk Genotypes: Relationship to Apoptosis and p53 Expression in Egyptian Patients with Laryngeal Carcinoma. Cancer genomics & proteomics. vol 1. issue 2. 2019-08-09. PMID:31394679. |
the relationship of hpv-16 and 18 genotypes to apoptosis and p53 protein expression in egyptian laryngeal carcinoma patients was studied. |
2019-08-09 |
2023-08-13 |
human |
| Samar K Kassim, Laila Seada, Samer Ibrahi. Human Papillomavirus High-risk Genotypes: Relationship to Apoptosis and p53 Expression in Egyptian Patients with Laryngeal Carcinoma. Cancer genomics & proteomics. vol 1. issue 2. 2019-08-09. PMID:31394679. |
in all specimens, hpv-16 and-18 were examined using pcr, p53 expression was studied by immunohistochemistry and dna fragmentation to assess apoptosis was assayed using a biochemical method and gel electrophoresis. |
2019-08-09 |
2023-08-13 |
human |
| Samar K Kassim, Laila Seada, Samer Ibrahi. Human Papillomavirus High-risk Genotypes: Relationship to Apoptosis and p53 Expression in Egyptian Patients with Laryngeal Carcinoma. Cancer genomics & proteomics. vol 1. issue 2. 2019-08-09. PMID:31394679. |
our results suggest that highly oncogenic types of hpv may play a role in the pathogenesis of laryngeal carcinoma through inactivation of wild-type p53 with subsequent decrease in apoptosis and by induction of p53 mutation, which itself can induce malignant transformation. |
2019-08-09 |
2023-08-13 |
human |
| Ahmed H Eid, Amany M Gad, Ebtehal Mohammad Fikry, Hany H Ara. Venlafaxine and carvedilol ameliorate testicular impairment and disrupted spermatogenesis in rheumatoid arthritis by targeting AMPK/ERK and PI3K/AKT/mTOR pathways. Toxicology and applied pharmacology. vol 364. 2019-08-08. PMID:30578887. |
with regard to apoptosis, the two agents lowered the protein expression of caspase-3, cleaved caspase-3, cleaved parp, bax and p53, promoting germ cell survival. |
2019-08-08 |
2023-08-13 |
rat |
| Liam Hayman, Wajeeh Raza Chaudhry, Victor V Revin, Nikolai Zhelev, Jean-Christophe Bourdo. What is the potential of p53 isoforms as a predictive biomarker in the treatment of cancer? Expert review of molecular diagnostics. vol 19. issue 2. 2019-08-08. PMID:30582376. |
the discovery of 12 human p53 isoforms expressed from 9 transcripts changed this perception, eloquently explaining the numerous roles p53 plays, including apoptosis, senescence, and regeneration. |
2019-08-08 |
2023-08-13 |
human |
| Chao-Yue Sun, Juan Nie, Zuo-Liang Zheng, Jie Zhao, Liu-Mei Wu, Ying Zhu, Zu-Qing Su, Guang-Juan Zheng, Bing Fen. Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-08-08. PMID:30797149. |
similarly, scutellarin administration inhibited apoptosis triggered by cisplatin through reducing the expressions of cleaved caspase-3, cleaved parp, p53, and the ratio of bax/bcl-2. |
2019-08-08 |
2023-08-13 |
mouse |
| Liubing Hu, Yan Wang, Zui Chen, Liangshun Fu, Sheng Wang, Xinyue Zhang, Pengchao Zhang, Xueping Lu, Huiyang Jie, Manmei Li, Yifei Wang, Zhong Li. Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway. Oxidative medicine and cellular longevity. vol 2019. 2019-08-08. PMID:31019655. |
ros scavenger nac rescued snx-2112/trail-induced apoptosis and suppressed snx-2112-induced p-jnk and p53. |
2019-08-08 |
2023-08-13 |
human |
| Qianying Liu, Zhixin Lei, Kaixiang Zhou, Huiru Yu, Shenhe Liu, Qiliang Sun, Xu Wang, Menghong Dai, Zonghui Yua. N-O Reduction and ROS-Mediated AKT/FOXO1 and AKT/P53 Pathways Are Involved in Growth Promotion and Cytotoxicity of Cyadox. Chemical research in toxicology. vol 31. issue 11. 2019-08-06. PMID:30265530. |
additionally, the activated p53 pathway, hyperactivated akt, and apoptosis were found in l02 cells after incubation with 100 μm cyadox. |
2019-08-06 |
2023-08-13 |
Not clear |
| Lingyao Wang, Tong Zhao, Song Wang, Jingji Jin, Yong Cai, Fei Wan. Expression, purification, and Bioscience, biotechnology, and biochemistry. vol 83. issue 7. 2019-08-06. PMID:30898040. |
besides the transactivation of downstream genes encoding proapoptotic proteins, p53 is also able to physically interact with mitochondria and induce apoptosis through a so called transcriptional-independent pathway. |
2019-08-06 |
2023-08-13 |
Not clear |
| Chao Mao, Xiang Wang, Yating Liu, Min Wang, Bin Yan, Yiqun Jiang, Ying Shi, Yi Shen, Xiaoli Liu, Weiwei Lai, Rui Yang, Desheng Xiao, Yan Cheng, Shuang Liu, Hu Zhou, Ya Cao, Weishi Yu, Kathrin Muegge, Herbert Yu, Yongguang Ta. A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53. Cancer research. vol 78. issue 13. 2019-08-05. PMID:29588351. |
a g3bp1-interacting lncrna promotes ferroptosis and apoptosis in cancer via nuclear sequestration of p53. |
2019-08-05 |
2023-08-13 |
Not clear |
| Chao Mao, Xiang Wang, Yating Liu, Min Wang, Bin Yan, Yiqun Jiang, Ying Shi, Yi Shen, Xiaoli Liu, Weiwei Lai, Rui Yang, Desheng Xiao, Yan Cheng, Shuang Liu, Hu Zhou, Ya Cao, Weishi Yu, Kathrin Muegge, Herbert Yu, Yongguang Ta. A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53. Cancer research. vol 78. issue 13. 2019-08-05. PMID:29588351. |
the cytosolic p53rra-g3bp1 interaction displaced p53 from a g3bp1 complex, resulting in greater p53 retention in the nucleus, which led to cell-cycle arrest, apoptosis, and ferroptosis. |
2019-08-05 |
2023-08-13 |
Not clear |
| Hussin A Rothan, Shengyun Fang, Mohan Mahesh, Siddappa N Byraredd. Zika Virus and the Metabolism of Neuronal Cells. Molecular neurobiology. vol 56. issue 4. 2019-08-02. PMID:30043260. |
in this review, we highlighted the fact that the activation of p53 and inhibition of the mtor pathway by zikv infection to neuronal stem cells induces early shifting from glycolysis to oxidative phosphorylation (oxphos) may induce immature differentiation, apoptosis, and stem cell exhaustion. |
2019-08-02 |
2023-08-13 |
Not clear |
| Dawei Sun, Wenying Wang, Xintao Wang, Yan Wang, Xiaotao Xu, Feng Ping, Yu Du, Wei Jiang, Derong Cu. bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats. Cell death & disease. vol 9. issue 2. 2019-08-01. PMID:29416039. |
apoptosis was induced after tgci and could be attenuated by bfgf treatment via inhibition of p53 mitochondrial translocation. |
2019-08-01 |
2023-08-13 |
rat |
| Dawei Sun, Wenying Wang, Xintao Wang, Yan Wang, Xiaotao Xu, Feng Ping, Yu Du, Wei Jiang, Derong Cu. bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats. Cell death & disease. vol 9. issue 2. 2019-08-01. PMID:29416039. |
in conclusion, these results demonstrate that bfgf could exert neuroprotective effects in the hippocampal ca1 region by suppressing excessive autophagy via the mtor pathway and inhibiting apoptosis by preventing p53 mitochondrial translocation. |
2019-08-01 |
2023-08-13 |
rat |
| Lei Zhao, Lina Fu, Zhongwei Xu, Rong Fan, Ruicheng Xu, Rong Fu, Shuang Zou, Congcong Wang, Yan Zhang, Jiabao Wang, Jun Bao, Zhimei Wang, Xiaojie Hou, Yupiao Zheng, Erqing Dai, Fengmei Wan. The anticancer effects of cinobufagin on hepatocellular carcinoma Huh‑7 cells are associated with activation of the p73 signaling pathway. Molecular medicine reports. vol 19. issue 5. 2019-08-01. PMID:30942456. |
conversely, the expression levels of bcl‑2‑associated x protein, p21, p53 upregulated modulator of apoptosis and phorbol‑12‑myristate‑13‑acetate‑induced protein 1, were significantly increased by cinobufagin treatment. |
2019-08-01 |
2023-08-13 |
mouse |
| Milos Hadzi-Mihailovic, Renata Petrovic, Helene Raybaud, Dragan Stanimirovic, Meltem Ozar Kora. Expression and role of p53 in oral lichen planus patients. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 22. issue 5. 2019-07-31. PMID:29135114. |
p53 plays an important role in cell cycle control and apoptosis and loss of p53 function has been demonstrated in about half of all human cancers. |
2019-07-31 |
2023-08-13 |
human |
| Lin Hou, Yinling Zhang, Xuemei Yang, Chunyu Tian, Yingshan Yan, Hongling Zhang, Jinjin Shi, Huijuan Zhang, Zhenzhong Zhan. Intracellular NO-Generator Based on Enzyme Trigger for Localized Tumor-Cytoplasm Rapid Drug Release and Synergetic Cancer Therapy. ACS applied materials & interfaces. vol 11. issue 1. 2019-07-31. PMID:30561993. |
moreover, expression of p53 protein was upregulated in tumor tissue after treatment, indicating that no induced cell apoptosis mediated by tumor suppressor gene p53. |
2019-07-31 |
2023-08-13 |
Not clear |
| Mengqin Shen, Xiaoping Zhao, Li Zhao, Liang Shi, Shuxian An, Gang Huang, Jianjun Li. Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer. Molecular cancer. vol 17. issue 1. 2019-07-30. PMID:29753331. |
tigar is a p53 target gene that is known to protect cells from ros-induced apoptosis by promoting the pentose phosphate pathway. |
2019-07-30 |
2023-08-13 |
Not clear |
| Mohammad A Ebrahimzadeh, Alireza Tafazoli, Javad Akhtari, Pourya Biparva, Shahram Eslam. Engineered Silver Nanoparticles, A New Nanoweapon Against Cancer. Anti-cancer agents in medicinal chemistry. vol 18. issue 14. 2019-07-30. PMID:30088451. |
investigations indicated the anticancer activity of agnps in different ways, comprising cell cycle arrest, dna damaging and apoptosis, alteration of p53 function, up/down regulation of some important cytokine genes and so on. |
2019-07-30 |
2023-08-13 |
Not clear |