| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chao Tang, Jin Wang, Qi Wei, Yi-Peng Du, He-Ping Qiu, Chao Yang, Yu-Chuan Ho. Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma. Oncology letters. vol 15. issue 5. 2020-09-30. PMID:29731872. |
comet assay and western blotting results demonstrated that tpm1 overexpression induced dna damage and decreased the expression levels of the antiapoptotic factor bcl2 apoptosis regulator, while increasing the expression levels of the proapoptotic factors bcl2 associated x, caspase-3 and p53 in 786-o and achn cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Qingxiong Yu, Min Wu, Lingling Sheng, Qingfeng Li, Feng Xi. Therapeutic effects of targeting RAS-ERK signaling in giant congenital melanocytic nevi. American journal of translational research. vol 10. issue 4. 2020-09-30. PMID:29736211. |
after inhibitor treatment, gncs were analyzed for apoptosis and the protein expression of erk, p-erk, p38, p-p38 and p53. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mathumai Kanapathipilla. Treating p53 Mutant Aggregation-Associated Cancer. Cancers. vol 10. issue 6. 2020-09-30. PMID:29789497. |
under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and dna repair. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yuchen Wang, Huali Xu, Zeyuan Lu, Xiaofeng Yu, Chen Lv, Yuan Tian, Dayun Su. Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway. Experimental and therapeutic medicine. vol 15. issue 6. 2020-09-30. PMID:29805515. |
pseudo-g-rh2-induced apoptosis was accompanied by sustained phosphorylation of ras, raf, extracellular signal-regulated kinase (erk) and p53. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yan Feng, Liqun Wang, Xin Liu, Qiang Wu, Haofeng Zhang, Fuguang Hu, Xiaofeng Su. Human corticotrophin releasing factor inhibits cell proliferation and promotes apoptosis through upregulation of tumor protein p53 in human glioma. Oncology letters. vol 15. issue 6. 2020-09-30. PMID:29805572. |
human corticotrophin releasing factor inhibits cell proliferation and promotes apoptosis through upregulation of tumor protein p53 in human glioma. |
2020-09-30 |
2023-08-13 |
human |
| Yan Feng, Liqun Wang, Xin Liu, Qiang Wu, Haofeng Zhang, Fuguang Hu, Xiaofeng Su. Human corticotrophin releasing factor inhibits cell proliferation and promotes apoptosis through upregulation of tumor protein p53 in human glioma. Oncology letters. vol 15. issue 6. 2020-09-30. PMID:29805572. |
finally, the present results suggest that hcrf inhibits proliferation and induces cell-cycle arrest and apoptosis in u87 cells via the crfr1-mediated p53 signaling pathway. |
2020-09-30 |
2023-08-13 |
human |
| Xin Li, Lei Xue, Qin Pen. Tunicamycin inhibits progression of glioma cells through downregulation of the MEG-3-regulated wnt/β-catenin signaling pathway. Oncology letters. vol 15. issue 6. 2020-09-30. PMID:29805584. |
in addition, tun treatment induced apoptosis of glioma cells through downregulation of bcl-2 and p53 expression levels. |
2020-09-30 |
2023-08-13 |
Not clear |
| Virginie Marcel, Flora Nguyen Van Long, Jean-Jacques Dia. 40 Years of Research Put p53 in Translation. Cancers. vol 10. issue 5. 2020-09-30. PMID:29883412. |
initially the tumor suppressor p53 protein was considered as a stress sensor able to maintain the genome integrity by regulating transcription of genes involved in cell cycle arrest, apoptosis and dna repair. |
2020-09-30 |
2023-08-13 |
Not clear |
| Dan Xu, Shuai Li, Limei Lin, Fei Qi, Xiaoming Hang, Yeqing Su. Gene expression profiling to identify the toxicities and potentially relevant disease outcomes due to endosulfan exposure. Toxicology research. vol 5. issue 2. 2020-09-30. PMID:30090376. |
these down-regulated genes were associated with cytoskeleton organization and dna repair at low doses, and involved in cell cycle, apoptosis, p53 pathway and carcinogenesis at high doses. |
2020-09-30 |
2023-08-13 |
human |
| Xia Cui, Jiayi Wang, Nannan Qiu, Yongning W. Toxicology research. vol 5. issue 2. 2020-09-30. PMID:30090383. |
further analysis indicated that high concentration of ec induced cell apoptosis, inhibited the g1 to s phase transition along with increased expression of p53 and p21 and decreased the expression of cyclin e and cdk 2, but no significant change in p27 expression was observed, which were evidenced by both real time pcr and western blotting analyses. |
2020-09-30 |
2023-08-13 |
human |
| Guofa Ren, Jingwen Hu, Yu Shang, Yufang Zhong, Zhiqiang Yu, Jing A. Tributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) induced apoptosis and cell cycle arrest in HepG2 cells. Toxicology research. vol 6. issue 6. 2020-09-30. PMID:30090552. |
tbp and tbep could induce both mitochondrial and p53 mediated apoptosis through different mitogen-activated protein kinase (mapk) signal pathways. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sibo Li, Haitao Jiang, Xiaohua G. Echinacoside suppresses dexamethasone-induced growth inhibition and apoptosis in osteoblastic MC3T3-E1 cells. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30112029. |
ech (10 mg/l) or pifithrin-α (pft-α) (a p53 inhibitor, 20 µm) suppressed dexamethasone-induced mc3t3-e1 apoptosis as illustrated by annexin v/propidium iodide (pi) double-labeling flow cytometry analysis. |
2020-09-30 |
2023-08-13 |
human |
| Jingwang Ye, Jing Li, Xiangfeng Wang, Ling L. Medicinal supplement genipin induces p53 and Bax-dependent apoptosis in colon cancer cells. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30127884. |
medicinal supplement genipin induces p53 and bax-dependent apoptosis in colon cancer cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Suiliang Zhang, Liang Sui, Juhua Zhuang, Saifei He, Yanan Song, Ying Ye, Wei Xi. ARHGAP24 regulates cell ability and apoptosis of colorectal cancer cells via the regulation of P53. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30127956. |
arhgap24 regulates cell ability and apoptosis of colorectal cancer cells via the regulation of p53. |
2020-09-30 |
2023-08-13 |
human |
| Guangyi Qin, Ping Li, Zhuowei Xu. Triptolide induces protective autophagy and apoptosis in human cervical cancer cells by downregulating Akt/mTOR activation. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30128010. |
these results suggested that triptolide induces protective autophagy, suppresses cell viability and promotes apoptosis in human cervical cancer cells by inducing the autophagy-targeting phosphoinositide 3-kinase/akt/mtor, p38, mapk, p53 and foxo3a pathways. |
2020-09-30 |
2023-08-13 |
human |
| Shiyang Ma, Yali Lei, Li Zhang, Jinhai Wan. Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels. Oncology letters. vol 16. issue 4. 2020-09-30. PMID:30197671. |
effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on p53 and bcl-2 expression levels. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shiyang Ma, Yali Lei, Li Zhang, Jinhai Wan. Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels. Oncology letters. vol 16. issue 4. 2020-09-30. PMID:30197671. |
the effects of zerumbone on the proliferation and apoptosis of esophagus cancer cells and on the p53 and bcl-2 expression levels were studied. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shiyang Ma, Yali Lei, Li Zhang, Jinhai Wan. Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels. Oncology letters. vol 16. issue 4. 2020-09-30. PMID:30197671. |
zerumbone can inhibit the proliferation and induce apoptosis of esophageal cancer ec-109 cells, and its induction of apoptosis may be realized through upregulating the mrna expression of p53 and downregulating the mrna expression of bcl-2, and upregulating the protein expression of p53 and downregulating the protein expression of bcl-2. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ying Zhang, Collin Dube, Myron Gibert, Nichola Cruickshanks, Baomin Wang, Maeve Coughlan, Yanzhi Yang, Initha Setiady, Ciana Deveau, Karim Saoud, Cassandra Grello, Madison Oxford, Fang Yuan, Roger Abounade. The p53 Pathway in Glioblastoma. Cancers. vol 10. issue 9. 2020-09-30. PMID:30200436. |
the tumor suppressor and transcription factor p53 plays critical roles in tumor prevention by orchestrating a wide variety of cellular responses, including damaged cell apoptosis, maintenance of genomic stability, inhibition of angiogenesis, and regulation of cell metabolism and tumor microenvironment. |
2020-09-30 |
2023-08-13 |
Not clear |
| Gita Shafiee, Yazdan Asgari, Akbar Soltani, Bagher Larijani, Ramin Heshma. Identification of candidate genes and proteins in aging skeletal muscle (sarcopenia) using gene expression and structural analysis. PeerJ. vol 6. 2020-09-30. PMID:30202641. |
p53 is recognized as a central regulator of the cell cycle and apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |