| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng-Jung Ho, Ru-Wei Lin, Wei-Hua Zhu, Tsung-Kai Wen, Chieh-Ju Hu, Yi-Lin Lee, Ta-I Hung, Chihuei Wan. Transcription-independent and -dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress. Cell death discovery. vol 5. 2020-10-01. PMID:31482012. |
the results suggested that p53 translocation from cytoplasm to nucleus actively drives cells toward apoptosis in either transcription-dependent or -independent manner for responding to non-genotoxic or genotoxic stress, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |
| Fang Yuan, Jinliang Wang, Ruixin Li, Xiao Zhao, Yuxuan Zhang, Biao Liu, Yonghong Lei, Yi H. A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines. Cancer management and research. vol 11. 2020-10-01. PMID:31576168. |
a new regulatory mechanism between p53 and yap crosstalk by sirt1 mediated deacetylation to regulate cell cycle and apoptosis in a549 cell lines. |
2020-10-01 |
2023-08-13 |
Not clear |
| Fang Yuan, Jinliang Wang, Ruixin Li, Xiao Zhao, Yuxuan Zhang, Biao Liu, Yonghong Lei, Yi H. A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines. Cancer management and research. vol 11. 2020-10-01. PMID:31576168. |
p53 is a key transcriptional regulator that responds to a variety of cellular stresses and regulates key cellular processes such as dna repair, cell-cycle progression, angiogenesis, and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Siying Li, Xiaoling Hong, Zhentong Wei, Min Xie, Wanying Li, Guanchen Liu, Haoran Guo, Jiaxin Yang, Wei Wei, Songling Zhan. Ubiquitination of the HPV Oncoprotein E6 Is Critical for E6/E6AP-Mediated p53 Degradation. Frontiers in microbiology. vol 10. 2020-10-01. PMID:31749782. |
crucially, ectopic expression of either p53 r175h or usp15 promoted p53-triggered apoptosis in human cervical cancer cells. |
2020-10-01 |
2023-08-13 |
human |
| Adoración G Quiroga, Marta Cama, Natalia Pajuelo-Lozano, Amparo Álvarez-Valdés, Isabel Sanchez Pere. New Findings in the Signaling Pathways of ACS omega. vol 4. issue 26. 2020-10-01. PMID:31891063. |
chlorido drugs showed similar behavior to cisplatin; they both required p53 to induce apoptosis but only |
2020-10-01 |
2023-08-13 |
Not clear |
| Brett Rozeboom, Nandini Dey, Pradip D. ER+ metastatic breast cancer: past, present, and a prescription for an apoptosis-targeted future. American journal of cancer research. vol 9. issue 12. 2020-10-01. PMID:31911865. |
the p53 and bcl2 represent two important nodes of the apoptosis signaling pathway. |
2020-10-01 |
2023-08-13 |
Not clear |
| Brett Rozeboom, Nandini Dey, Pradip D. ER+ metastatic breast cancer: past, present, and a prescription for an apoptosis-targeted future. American journal of cancer research. vol 9. issue 12. 2020-10-01. PMID:31911865. |
our review presents critical analyses of the therapeutic options for the clinical management of er+ metastatic breast cancer in the light of a hypothesis targeting the induction of apoptosis in p53 wild type tumors. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yameng Zhang, Chao Li, Shanmei Sun, Zhiqun Cao, Jian Chen, Hongjie Xiang, Lucheng Son. Screening and Identification of Molecular Targets Involved in Preventing Gastric Precancerous Lesions in Chronic Atrophic Gastritis by Qilianshupi Decoction. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-10-01. PMID:31929816. |
network pharmacology analysis revealed that the 6 herbs regulated multiple cag-related genes, among which the most important were cancer-related pathway (apoptosis, p53, and vegf) and epithelial cell signaling in |
2020-10-01 |
2023-08-13 |
Not clear |
| Dan-Yang Li, Jing-Dong Song, Zhao-Yuan Liang, Kiana Oskouei, Xiang-Qian Xiao, Wen-Zhe Hou, Jin-Tao Li, Yi-Shu Yang, Ming-Lian Wang, Manuel Murbac. Apoptotic Effect of 1800 MHz Electromagnetic Radiation on NIH/3T3 Cells. International journal of environmental research and public health. vol 17. issue 3. 2020-10-01. PMID:32013005. |
to investigate the effect of 1800 mhz electromagnetic radiation (emr) on apoptosis, we exposed nih/3t3 cells at 1800 mhz with a specific absorption rate (sar) of 2 w/kg intermittently for 12, 24, 36, and 48 h. after exposure, cell counting kit-8 (cck-8) and flow cytometry were used to detect cell viability and apoptosis; the expression of p53, a molecule with the key role in apoptosis, was measured by real-time qpcr, western blot, and immunofluorescence; and images of the structure of the mitochondria, directly reflecting apoptosis, were captured by electron microscopy. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dan-Yang Li, Jing-Dong Song, Zhao-Yuan Liang, Kiana Oskouei, Xiang-Qian Xiao, Wen-Zhe Hou, Jin-Tao Li, Yi-Shu Yang, Ming-Lian Wang, Manuel Murbac. Apoptotic Effect of 1800 MHz Electromagnetic Radiation on NIH/3T3 Cells. International journal of environmental research and public health. vol 17. issue 3. 2020-10-01. PMID:32013005. |
these findings demonstrated 1800 mhz, sar 2 w/kg emr for 48 h may cause apoptosis in nih/3t3 cells and that this apoptosis might be attributed to mitochondrial damage and upregulation of p53 expression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Liang Li, Ying Xu, Binquan Wan. Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression. Oncology letters. vol 9. issue 3. 2020-10-01. PMID:25663867. |
liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression. |
2020-10-01 |
2023-08-13 |
human |
| Qingwei Kang, Shu Ya. Piperlongumine reverses doxorubicin resistance through the PI3K/Akt signaling pathway in K562/A02 human leukemia cells. Experimental and therapeutic medicine. vol 9. issue 4. 2020-10-01. PMID:25780433. |
the results indicated that piperlongumine promoted doxorubicin sensitivity, apoptosis, the intracellular accumulation of rhodamine-123, the activities of caspase-3 and -8, and the expression of reactive oxygen species, p53, p27 and p-pten. |
2020-10-01 |
2023-08-13 |
human |
| Rahul Kumar, Gagan Deep, Rajesh Agarwa. An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin. Current pharmacology reports. vol 1. issue 3. 2020-10-01. PMID:26097804. |
molecular studies have identified that silibinin targets pleotropic signaling pathways including mitogenic, cell cycle, apoptosis, autophagy, p53, nf-κb, etc. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shuo Tu, Xiali Zhang, Daya Luo, Zhuoqi Liu, Xiaohong Yang, Huifang Wan, Lehan Yu, Hua Li, Fusheng Wa. Effect of taurine on the proliferation and apoptosis of human hepatocellular carcinoma HepG2 cells. Experimental and therapeutic medicine. vol 10. issue 1. 2020-10-01. PMID:26170934. |
the p53 upregulated modulator of apoptosis (puma) gene was transiently transfected by lipofection and subsequently silenced with specific small interfering (si)rna. |
2020-10-01 |
2023-08-13 |
human |
| Y U Wang, Yi-Ni Chen, Wei Zhang, Y U Yang, Wen-Kun Bai, E Shen, Bing H. Upregulation of ULK1 expression in PC-3 cells following tumor protein P53 transfection by sonoporation. Oncology letters. vol 11. issue 1. 2020-10-01. PMID:26870270. |
p53 has a significant role in a number of key biological functions, including dna repair, apoptosis, cell cycle, autophagy, senescence and angiogenesis. |
2020-10-01 |
2023-08-13 |
human |
| A Lakoma, E Barbieri, S Agarwal, J Jackson, Z Chen, Y Kim, M McVay, J M Shohet, E S Ki. The MDM2 small-molecule inhibitor RG7388 leads to potent tumor inhibition in p53 wild-type neuroblastoma. Cell death discovery. vol 1. 2020-10-01. PMID:26998348. |
cell viability and apoptosis studies were performed on the neuroblastoma cell lines, ngp, sh-sy5y, lan-5, lan-5 si-p53 (p53 silenced), and sk-n-as (p53 null). |
2020-10-01 |
2023-08-13 |
mouse |
| Huan Wang, Xiaoli Zhu, Jing Huang, Pingsheng Chen, Shuhua Han, Xing Ya. Nedaplatin sensitization of cisplatin-resistant human non-small cell lung cancer cells. Oncology letters. vol 11. issue 4. 2020-10-01. PMID:27073518. |
furthermore, western blot analysis indicated that ndp decreased the protein expression of p-glycoprotein, tumor protein p53 and b-cell lymphoma 2, and increased the expression of bcl-2-associated x protein, all of which could possibly improve the ndp intracellular drug concentration and promote cell apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Peiyan Hua, Guangxin Zhang, Yifan Zhang, Mei Sun, Ranji Cui, Xin Li, Bingjin Li, Xingyi Zhan. Costunolide induces G1/S phase arrest and activates mitochondrial-mediated apoptotic pathways in SK-MES 1 human lung squamous carcinoma cells. Oncology letters. vol 11. issue 4. 2020-10-01. PMID:27073552. |
through upregulation in the expression of p53 and bax, and downregulation in the expression of bcl-2 and activation of caspase-3, costunolide-induced apoptosis was confirmed by western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Jekaterina Erenpreisa, M S Crag. Mitotic death: a mechanism of survival? A review. Cancer cell international. vol 1. issue 1. 2020-09-30. PMID:11983025. |
after uncoupling apoptosis from g1 and s phase arrests and adapting these checkpoints, p53 mutated tumour cells arrive at the g2 compartment where decisions regarding survival and death are made. |
2020-09-30 |
2023-08-12 |
Not clear |
| Silvano Nocentin. Apoptotic response of malignant rhabdoid tumor cells. Cancer cell international. vol 3. issue 1. 2020-09-30. PMID:12904267. |
conclusion: these results suggest abnormalities in the p53 pathway and apoptosis control in mrt cells. |
2020-09-30 |
2023-08-12 |
Not clear |