| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Therese Bredholt Onyango, Sigrun M Hjelle, Ingvild Haaland, Olav K Vintermyr, Anne Christine Johannessen, Bjørn Tore Gjertse. A Comparison of p53 Isoform Profiles and Apoptosis Induced by Camptothecin or a Herbal Khat Extract ( Cancers. vol 12. issue 12. 2020-12-26. PMID:33271840. |
a comparison of p53 isoform profiles and apoptosis induced by camptothecin or a herbal khat extract ( khat ( |
2020-12-26 |
2023-08-13 |
Not clear |
| Elina Ly, Jennifer F Kugel, James A Goodric. Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites. Scientific reports. vol 10. issue 1. 2020-12-24. PMID:32999415. |
the tumor suppressor protein p53 is critical for cell fate decisions, including apoptosis, senescence, and cell cycle arrest. |
2020-12-24 |
2023-08-13 |
Not clear |
| Giovanni Blandino, Fabio Valenti, Andrea Sacconi, Silvia Di Agostin. Wild type- and mutant p53 proteins in mitochondrial dysfunction: emerging insights in cancer disease. Seminars in cell & developmental biology. vol 98. 2020-12-22. PMID:31112799. |
the ability of p53 to induce apoptosis acting directly at mitochondria and the related mechanisms of p53 localization and translocation in the cytoplasm have been investigated. |
2020-12-22 |
2023-08-13 |
human |
| Nishat Fatima, Syed Habeeb Ahmed, S S Chauhan, Owais Mohammad, Syed Mohd Fazlur Rehma. Structural equation modelling analysis determining causal role among methyltransferases, methylation, and apoptosis during human pregnancy and abortion. Scientific reports. vol 10. issue 1. 2020-12-21. PMID:32709893. |
a significant and negative correlation (with p-value < 0.001) between the degree of p53 methylation during the first trimester and that of the expression level of tunel assay (apoptosis), p53, bax, and caspase-6 are also observed in the present study. |
2020-12-21 |
2023-08-13 |
human |
| Nishat Fatima, Syed Habeeb Ahmed, S S Chauhan, Owais Mohammad, Syed Mohd Fazlur Rehma. Structural equation modelling analysis determining causal role among methyltransferases, methylation, and apoptosis during human pregnancy and abortion. Scientific reports. vol 10. issue 1. 2020-12-21. PMID:32709893. |
a positive correlation between apoptosis and a higher level of p53 expression (which is possibly due to low degree of p53 methylation) is observed both at the transcript and protein level in ursa which is in line with our findings. |
2020-12-21 |
2023-08-13 |
human |
| Nishat Fatima, Syed Habeeb Ahmed, S S Chauhan, Owais Mohammad, Syed Mohd Fazlur Rehma. Structural equation modelling analysis determining causal role among methyltransferases, methylation, and apoptosis during human pregnancy and abortion. Scientific reports. vol 10. issue 1. 2020-12-21. PMID:32709893. |
the analysis performed using structural equation modelling (sem) further throws light on the causal relationship between sustenance of pregnancy or ursa during the first trimester of a human pregnancy and degree of methylation of p53 which is closely correlated with the interaction between g9amt, dnmt1, bcl-2, bax, p53, caspase-6, and apoptosis. |
2020-12-21 |
2023-08-13 |
human |
| Jun Qiang, Jie He, Yi-Fan Tao, Jin-Wen Bao, Jun-Hao Zhu, Pao X. Hypoxia-induced miR-92a regulates p53 signaling pathway and apoptosis by targeting calcium-sensing receptor in genetically improved farmed tilapia (Oreochromis niloticus). PloS one. vol 15. issue 11. 2020-12-21. PMID:33180826. |
hypoxia-induced mir-92a regulates p53 signaling pathway and apoptosis by targeting calcium-sensing receptor in genetically improved farmed tilapia (oreochromis niloticus). |
2020-12-21 |
2023-08-13 |
Not clear |
| Yeong-Seon Won, Kwon-Il Se. Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells. Nutrients. vol 12. issue 2. 2020-12-17. PMID:32075054. |
sanggenol l induces apoptosis and cell cycle arrest via activation of p53 and suppression of pi3k/akt/mtor signaling in human prostate cancer cells. |
2020-12-17 |
2023-08-13 |
human |
| Sarah Hassan, Jean Peluso, Sandra Chalhoub, Ysia Idoux Gillet, Nadia Benkirane-Jessel, Natacha Rochel, Guy Fuhrmann, Genevieve Ubeaud-Sequie. Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1. PloS one. vol 15. issue 10. 2020-12-17. PMID:33052979. |
in addition, our results indicated that the combination of anti-cancer drugs and quercetin down-regulated the expression of hif-1α and increased the expression levels of the regulator of apoptosis p53. |
2020-12-17 |
2023-08-13 |
human |
| Chenxi Xu, Jianjian Zhuang, Xiaobo Zhan. 2-[(4-Hydroxybenzyl) Amino] Phenol (HBAP) Restores the Mutated p53 to the Level Similar to That of Wild-Type p53 Protein and Inhibits Breast Cancer Growth Frontiers in cell and developmental biology. vol 8. 2020-12-17. PMID:33324634. |
2-[(4-hydroxybenzyl) amino] phenol (hbap) restores the mutated p53 to the level similar to that of wild-type p53 protein and inhibits breast cancer growth p53 is a transcriptional factor that plays important roles in apoptosis and is mutated in more than 50% of tumor cells. |
2020-12-17 |
2023-08-13 |
Not clear |
| Jingzi Quan, Dongfang Dong, Yue Lun, Bo Sun, Haiyuan Sun, Qunying Wang, Gang Yua. Circular RNA circHIAT1 inhibits proliferation and epithelial-mesenchymal transition of gastric cancer cell lines through downregulation of miR-21. Journal of biochemical and molecular toxicology. vol 34. issue 4. 2020-12-16. PMID:32020707. |
after transfection with plcdh-circhiat1 in mkn28 and mkn45 cells, cell viability was decreased, while the expression levels of p53 and p21 were raised, as well as apoptosis. |
2020-12-16 |
2023-08-13 |
Not clear |
| Han Gao, Tian Wang, Peng Zhang, Muhe Shang, Zhikui Gao, Fei Yang, Ran Li. Linc-ROR regulates apoptosis in esophageal squamous cell carcinoma via modulation of p53 ubiquitination by targeting miR-204-5p/MDM2. Journal of cellular physiology. vol 235. issue 3. 2020-12-15. PMID:31541467. |
linc-ror regulates apoptosis in esophageal squamous cell carcinoma via modulation of p53 ubiquitination by targeting mir-204-5p/mdm2. |
2020-12-15 |
2023-08-13 |
Not clear |
| Han Gao, Tian Wang, Peng Zhang, Muhe Shang, Zhikui Gao, Fei Yang, Ran Li. Linc-ROR regulates apoptosis in esophageal squamous cell carcinoma via modulation of p53 ubiquitination by targeting miR-204-5p/MDM2. Journal of cellular physiology. vol 235. issue 3. 2020-12-15. PMID:31541467. |
in summary, this study revealed that linc-ror modulated cell apoptosis and regulated p53 ubiquitination via targeting mir-204-5p/mdm2 axis, which provides a novel therapeutic insight into treatments for escc. |
2020-12-15 |
2023-08-13 |
Not clear |
| Feng-Yi Ke, Wan-Yu Chen, Ming-Chieh Lin, Yu-Chyi Hwang, Kuan-Ting Kuo, Han-Chung W. Novel monoclonal antibody against integrin α3 shows therapeutic potential for ovarian cancer. Cancer science. vol 111. issue 10. 2020-12-15. PMID:32648337. |
among these mabs, ov-ab 30-7 was found to target integrin α3 and upregulate p53 and p21, while stimulating the apoptosis of cancer cells. |
2020-12-15 |
2023-08-13 |
mouse |
| Arnab Banerjee, Debasmita Das, Rajarshi Paul, Sandipan Roy, Ujjal Das, Samrat Saha, Sanjit Dey, Arghya Adhikary, Sandip Mukherjee, Bithin Kumar Maj. Mechanistic study of attenuation of monosodium glutamate mixed high lipid diet induced systemic damage in rats by Coccinia grandis. Scientific reports. vol 10. issue 1. 2020-12-15. PMID:32963259. |
furthermore, eecgl significantly inhibited hm-induced increased population of cells in sub g0/g1 phase, decreased bcl2 expression and thereby loss of mitochondrial membrane potential with over expression of bax, p53, p21, activation of caspase 3 and 9 indicated the apoptosis and suppression of cell survival. |
2020-12-15 |
2023-08-13 |
rat |
| Sathiya Sekar, Changiz Taghibiglo. Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease. Neuroscience letters. vol 716. 2020-12-14. PMID:31759082. |
on the other hand, study on ischemic rat model showed that nucleus translocated gapdh binds with p53 leading to apoptosis. |
2020-12-14 |
2023-08-13 |
rat |
| Hongmei Jiao, Renyi Chen, Ziru Jiang, Lin Zhang, Hongwei Wan. miR-22 protect PC12 from ischemia/reperfusion-induced injury by targeting p53 upregulated modulator of apoptosis (PUMA). Bioengineered. vol 11. issue 1. 2020-12-14. PMID:32065044. |
mir-22 protect pc12 from ischemia/reperfusion-induced injury by targeting p53 upregulated modulator of apoptosis (puma). |
2020-12-14 |
2023-08-13 |
Not clear |
| Aeyung Kim, Seo-Young Lee, Chang-Seob Seo, Sun-Ku Chun. Prunellae Spica Extract Suppresses Teratoma Formation of Pluripotent Stem Cells through p53-Mediated Apoptosis. Nutrients. vol 12. issue 3. 2020-12-14. PMID:32182802. |
in p53 knockout (ko) ipscs, the eps did not induce apoptosis, indicating that eps-mediated apoptosis of uscs was p53-dependent. |
2020-12-14 |
2023-08-13 |
Not clear |
| Carla Pisani, Martina Ramella, Renzo Boldorini, Gianfranco Loi, Michele Billia, Francesca Boccafoschi, Alessandro Volpe, Marco Krengl. Apoptotic and predictive factors by Bax, Caspases 3/9, Bcl-2, p53 and Ki-67 in prostate cancer after 12 Gy single-dose. Scientific reports. vol 10. issue 1. 2020-12-14. PMID:32341393. |
radio-induced apoptosis is mediated by the activation of tumor protein p53, bax and caspases. |
2020-12-14 |
2023-08-13 |
Not clear |
| Hui-Chen Su, Sheng-Cheng Wu, Li-Chen Yen, Li-Kang Chiao, Jehng-Kang Wang, Yi-Lin Chiu, Ching-Liang Ho, Shih-Ming Huan. Gene expression profiling identifies the role of Zac1 in cervical cancer metastasis. Scientific reports. vol 10. issue 1. 2020-12-14. PMID:32678267. |
zac1 is postulated to be a tumor suppressor by inducing cell cycle arrest and apoptosis through interacting and modulating transcriptional activity of p53 as it was named. |
2020-12-14 |
2023-08-13 |
human |