| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ava Faridi, Yunxiang Sun, Monika Mortimer, Ritchlynn R Aranha, Aparna Nandakumar, Yuhuan Li, Ibrahim Javed, Aleksandr Kakinen, Qingqing Fan, Anthony W Purcell, Thomas P Davis, Feng Ding, Pouya Faridi, Pu Chun K. Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. Nano research. vol 12. issue 11. 2020-11-01. PMID:31695851. |
while iapp can activate the nlrp3 inflammasome and modulate cellular autophagy, apoptosis and extracellular matrix metabolism, no data is available concerning intracellular protein expression upon exposure to the polypeptide. |
2020-11-01 |
2023-08-13 |
human |
| R K Subbarao Malireddi, Prajwal Gurung, Sannula Kesavardhana, Parimal Samir, Amanda Burton, Harisankeerth Mummareddy, Peter Vogel, Stephane Pelletier, Sandeepta Burgula, Thirumala-Devi Kannegant. Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease. The Journal of experimental medicine. vol 217. issue 3. 2020-10-29. PMID:31869420. |
tlr priming of tak1-deficient macrophages triggered inflammasome activation, including the activation of caspase-8 and gasdermin d, and the recruitment of nlrp3 and asc into a novel ripk1 kinase activity-independent cell death complex to drive pyroptosis and apoptosis. |
2020-10-29 |
2023-08-13 |
Not clear |
| Kendra L Hanslik, Tyler K Ullan. The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease. Frontiers in neurology. vol 11. 2020-10-22. PMID:33071950. |
several recent reports indicate that the assembly of the multi-protein complex known as the nod, lrr, and pyrin-domain containing 3 (nlrp3) inflammasome by microglia results in apoptosis spec-like protein containing a card (asc) spec formation, which then nucleates new aβ plaques, thus amplifying aβ-associated pathology. |
2020-10-22 |
2023-08-13 |
Not clear |
| Ting Liu, Lantian Tang, Hui Tang, Jieying Pu, Sitang Gong, Danyun Fang, Hui Zhang, Yi-Ping Li, Xun Zhu, Weidong Wang, Minhao Wu, Yuhui Liao, Chunling Li, Haibo Zhou, Xi Huan. Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2. Frontiers in immunology. vol 10. 2020-10-05. PMID:31474993. |
overexpression of bcl-2 attenuated zikv-induced nlrp3 inflammasome activation in renal cells and down-regulated parp/caspase-3-mediated renal apoptosis. |
2020-10-05 |
2023-08-13 |
mouse |
| Ting Liu, Lantian Tang, Hui Tang, Jieying Pu, Sitang Gong, Danyun Fang, Hui Zhang, Yi-Ping Li, Xun Zhu, Weidong Wang, Minhao Wu, Yuhui Liao, Chunling Li, Haibo Zhou, Xi Huan. Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2. Frontiers in immunology. vol 10. 2020-10-05. PMID:31474993. |
overall, our findings demonstrated that zikv infection induced aki by activating nlrp3 inflammasome and apoptosis through suppressing bcl-2 expression, which provided potential therapeutic targets for zikv-associated renal diseases. |
2020-10-05 |
2023-08-13 |
mouse |
| Elnaz Hajipour, Farideh Jalali Mashayekhi, Ghasem Mosayebi, Maryam Baazm, Adib Zendede. Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model. Iranian journal of basic medical sciences. vol 21. issue 2. 2020-10-01. PMID:29456821. |
resveratrol decreases apoptosis and nlrp3 complex expressions in experimental varicocele rat model. |
2020-10-01 |
2023-08-13 |
rat |
| Elnaz Hajipour, Farideh Jalali Mashayekhi, Ghasem Mosayebi, Maryam Baazm, Adib Zendede. Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model. Iranian journal of basic medical sciences. vol 21. issue 2. 2020-10-01. PMID:29456821. |
due to the important role of antioxidant in decreasing the testis tissue damage, in this study we investigated the protective effect of resveratrol (res) on nlrp3 complex and apoptosis in experimental varicocele rats. |
2020-10-01 |
2023-08-13 |
rat |
| Richard E Kas. Inhibiting the NLRP3 Inflammasome With Methylene Blue as Treatment Adjunct in Myelodysplasia. Frontiers in oncology. vol 8. 2020-10-01. PMID:30101125. |
if as in rodents, methylene blue also inhibits nlrp3 inflammasome function in human myelodysplasia a trial of adjunctive methylene blue treatment in transfusion dependent, low risk myelodysplasia where marrow inflammation and apoptosis predominates, would be worth trying. |
2020-10-01 |
2023-08-13 |
human |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
mirna-223-3p regulates nlrp3 to promote apoptosis and inhibit proliferation of hep3b cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
the present study was performed to investigate the role of mir-223 in the proliferation and apoptosis of hcc cells through regulating nlrp3. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
mir-223 inhibited hcc cell proliferation and promoted apoptosis by directly targeting nlrp3. |
2020-09-30 |
2023-08-13 |
Not clear |
| Bour-Jr Wang, Hui-Wen Chiu, Yong-Lin Lee, Chia-Yi Li, Ying-Jan Wang, Yu-Hsuan Le. Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation. Journal of clinical medicine. vol 7. issue 12. 2020-09-30. PMID:30486377. |
pterostilbene attenuates hexavalent chromium-induced allergic contact dermatitis by preventing cell apoptosis and inhibiting il-1β-related nlrp3 inflammasome activation. |
2020-09-30 |
2023-08-13 |
mouse |
| Bour-Jr Wang, Hui-Wen Chiu, Yong-Lin Lee, Chia-Yi Li, Ying-Jan Wang, Yu-Hsuan Le. Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation. Journal of clinical medicine. vol 7. issue 12. 2020-09-30. PMID:30486377. |
furthermore, our current findings demonstrated that the nlrp3 inflammasome could be involved in the cr(vi)-mediated inflammation and apoptosis of acd. |
2020-09-30 |
2023-08-13 |
mouse |
| Xiao Bi, Jingjing Wang, Yuqing Liu, Yingdeng Wang, Wei Din. MnTBAP treatment ameliorates aldosterone-induced renal injury by regulating mitochondrial dysfunction and NLRP3 inflammasome signalling. American journal of translational research. vol 10. issue 11. 2020-09-30. PMID:30662603. |
in addition, mntbap treatment of aldosterone-infused mice significantly improved mitochondrial morphology and function, suppressed the activation of nlrp3 inflammasome, reduced renal tubular cell apoptosis, decreased phenotypic alterations, and ameliorated renal apoptosis. |
2020-09-30 |
2023-08-13 |
mouse |
| Benjamin Demarco, Kaiwen W Chen, Petr Bro. Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation. Molecular & cellular oncology. vol 6. issue 4. 2020-09-29. PMID:31211242. |
pannexin-1 channels bridge apoptosis to nlrp3 inflammasome activation. |
2020-09-29 |
2023-08-13 |
Not clear |
| Benjamin Demarco, Kaiwen W Chen, Petr Bro. Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation. Molecular & cellular oncology. vol 6. issue 4. 2020-09-29. PMID:31211242. |
apoptosis can promote inflammation by triggering activation of the nlrp3 inflammasome (nlr family, pyrin domain containing 3). |
2020-09-29 |
2023-08-13 |
Not clear |
| Lili Xu, Liyan Shen, Xiaolong Yu, Peng Li, Qing Wang, Chengqian L. Effects of irisin on osteoblast apoptosis and osteoporosis in postmenopausal osteoporosis rats through upregulating Nrf2 and inhibiting NLRP3 inflammasome. Experimental and therapeutic medicine. vol 19. issue 2. 2020-09-28. PMID:32010273. |
effects of irisin on osteoblast apoptosis and osteoporosis in postmenopausal osteoporosis rats through upregulating nrf2 and inhibiting nlrp3 inflammasome. |
2020-09-28 |
2023-08-13 |
rat |
| Lili Xu, Liyan Shen, Xiaolong Yu, Peng Li, Qing Wang, Chengqian L. Effects of irisin on osteoblast apoptosis and osteoporosis in postmenopausal osteoporosis rats through upregulating Nrf2 and inhibiting NLRP3 inflammasome. Experimental and therapeutic medicine. vol 19. issue 2. 2020-09-28. PMID:32010273. |
the nuclear factor e2-related factor 2 (nrf2)/nlr family, pyrin domain containing protein 3 (nlrp3) plays an important role in osteoporosis (op), so the effects of irisin on postmenopausal op rats and osteoblast apoptosis through nrf2/nlrp3 were explored in the present study. |
2020-09-28 |
2023-08-13 |
rat |
| Lili Xu, Liyan Shen, Xiaolong Yu, Peng Li, Qing Wang, Chengqian L. Effects of irisin on osteoblast apoptosis and osteoporosis in postmenopausal osteoporosis rats through upregulating Nrf2 and inhibiting NLRP3 inflammasome. Experimental and therapeutic medicine. vol 19. issue 2. 2020-09-28. PMID:32010273. |
after the trial period, the content of serum alp was detected, the levels of tumor necrosis factor-α (tnf-α) in the serum and bone tissues were observed via elisa, and the bone microstructure was observed via ct. osteoblast apoptosis was determined through tunel assay, the content of apoptosis genes caspase-3 and bcl-2, and key genes in runt-related transcription factor 2 (runx2), osteocalcin (oc), nrf2 and nlrp3 was detected via rt-pcr. |
2020-09-28 |
2023-08-13 |
rat |
| Lili Xu, Liyan Shen, Xiaolong Yu, Peng Li, Qing Wang, Chengqian L. Effects of irisin on osteoblast apoptosis and osteoporosis in postmenopausal osteoporosis rats through upregulating Nrf2 and inhibiting NLRP3 inflammasome. Experimental and therapeutic medicine. vol 19. issue 2. 2020-09-28. PMID:32010273. |
irisin can upregulate nrf2, inhibit nlrp3 inflammasome and lower the content of inflammatory factors, thereby suppressing osteoblast apoptosis in postmenopausal op rats and reducing the incidence of postmenopausal op. |
2020-09-28 |
2023-08-13 |
rat |