| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yicong Chang, Liang Yuan, Jiarui Liu, Ishfaq Muhammad, Chuanbao Cao, Chenxi Shi, Yuanyuan Zhang, Rui Li, Changwen Li, Fangping Li. Dihydromyricetin attenuates Escherichia coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3 inflammasome and TLR4/NF-κB signalling pathway. Veterinary research. vol 51. issue 1. 2021-01-05. PMID:32448367. |
in summary, dhm attenuated the ileum mucosal damage, oxidative stress and apoptosis, maintained barrier function, inhibited nlrp3 inflammasome and tlr4/nf-κb signalling pathway activation triggered by escherichia coli lps. |
2021-01-05 |
2023-08-13 |
chicken |
| Sannula Kesavardhana, R K Subbarao Malireddi, Amanda R Burton, Shaina N Porter, Peter Vogel, Shondra M Pruett-Miller, Thirumala-Devi Kannegant. The Zα2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development. The Journal of biological chemistry. vol 295. issue 24. 2020-12-30. PMID:32350114. |
zbp1 activation triggers inflammation and pyroptosis, necroptosis, and apoptosis (panoptosis) by activating receptor-interacting ser/thr kinase 3 (ripk3), caspase-8, and the nlrp3 inflammasome. |
2020-12-30 |
2023-08-13 |
Not clear |
| Marisol Fernández-Ortiz, Ramy K A Sayed, José Fernández-Martínez, Antonia Cionfrini, Paula Aranda-Martínez, Germaine Escames, Tomás de Haro, Darío Acuña-Castroviej. Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging. Antioxidants (Basel, Switzerland). vol 9. issue 12. 2020-12-26. PMID:33260800. |
with the aim of investigating the impact of nlrp3 inflammasome and the actions and target of melatonin in aged myocardium, we analyzed the expression of proteins implied in mitochondria dynamics, autophagy, apoptosis, nrf2-dependent antioxidant response and mitochondria ultrastructure in heart of wild-type and nlrp3-knockout mice of 3, 12, and 24 months-old, with and without melatonin treatment. |
2020-12-26 |
2023-08-13 |
mouse |
| Shuai Zhao, Fan Chen, Qiliang Yin, Dunwei Wang, Wei Han, Yuan Zhan. Reactive Oxygen Species Interact With NLRP3 Inflammasomes and Are Involved in the Inflammation of Sepsis: From Mechanism to Treatment of Progression. Frontiers in physiology. vol 11. 2020-12-17. PMID:33324236. |
nlrp3 inflammasomes enlarge the inflammatory response and trigger apoptosis of immune cells to exacerbate sepsis progression. |
2020-12-17 |
2023-08-13 |
Not clear |
| Tao Pan, Qiu-Jiao Zhu, Li-Xiao Xu, Xin Ding, Jian-Qin Li, Bin Sun, Jun Hua, Xing Fen. Knocking down TRPM2 expression reduces cell injury and NLRP3 inflammasome activation in PC12 cells subjected to oxygen-glucose deprivation. Neural regeneration research. vol 15. issue 11. 2020-12-11. PMID:32394974. |
taken together, these results suggest that trpm2 knockdown reduces ogd-induced neuronal injury, potentially by inhibiting apoptosis and reducing oxidative stress levels, mitochondrial membrane potentials, intracellular calcium concentrations, and nlrp3 inflammasome activation. |
2020-12-11 |
2023-08-13 |
Not clear |
| Ava Faridi, Yunxiang Sun, Monika Mortimer, Ritchlynn R Aranha, Aparna Nandakumar, Yuhuan Li, Ibrahim Javed, Aleksandr Kakinen, Qingqing Fan, Anthony W Purcell, Thomas P Davis, Feng Ding, Pouya Faridi, Pu Chun K. Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. Nano research. vol 12. issue 11. 2020-11-01. PMID:31695851. |
while iapp can activate the nlrp3 inflammasome and modulate cellular autophagy, apoptosis and extracellular matrix metabolism, no data is available concerning intracellular protein expression upon exposure to the polypeptide. |
2020-11-01 |
2023-08-13 |
human |
| R K Subbarao Malireddi, Prajwal Gurung, Sannula Kesavardhana, Parimal Samir, Amanda Burton, Harisankeerth Mummareddy, Peter Vogel, Stephane Pelletier, Sandeepta Burgula, Thirumala-Devi Kannegant. Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease. The Journal of experimental medicine. vol 217. issue 3. 2020-10-29. PMID:31869420. |
tlr priming of tak1-deficient macrophages triggered inflammasome activation, including the activation of caspase-8 and gasdermin d, and the recruitment of nlrp3 and asc into a novel ripk1 kinase activity-independent cell death complex to drive pyroptosis and apoptosis. |
2020-10-29 |
2023-08-13 |
Not clear |
| Kendra L Hanslik, Tyler K Ullan. The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease. Frontiers in neurology. vol 11. 2020-10-22. PMID:33071950. |
several recent reports indicate that the assembly of the multi-protein complex known as the nod, lrr, and pyrin-domain containing 3 (nlrp3) inflammasome by microglia results in apoptosis spec-like protein containing a card (asc) spec formation, which then nucleates new aβ plaques, thus amplifying aβ-associated pathology. |
2020-10-22 |
2023-08-13 |
Not clear |
| Ting Liu, Lantian Tang, Hui Tang, Jieying Pu, Sitang Gong, Danyun Fang, Hui Zhang, Yi-Ping Li, Xun Zhu, Weidong Wang, Minhao Wu, Yuhui Liao, Chunling Li, Haibo Zhou, Xi Huan. Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2. Frontiers in immunology. vol 10. 2020-10-05. PMID:31474993. |
overexpression of bcl-2 attenuated zikv-induced nlrp3 inflammasome activation in renal cells and down-regulated parp/caspase-3-mediated renal apoptosis. |
2020-10-05 |
2023-08-13 |
mouse |
| Ting Liu, Lantian Tang, Hui Tang, Jieying Pu, Sitang Gong, Danyun Fang, Hui Zhang, Yi-Ping Li, Xun Zhu, Weidong Wang, Minhao Wu, Yuhui Liao, Chunling Li, Haibo Zhou, Xi Huan. Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2. Frontiers in immunology. vol 10. 2020-10-05. PMID:31474993. |
overall, our findings demonstrated that zikv infection induced aki by activating nlrp3 inflammasome and apoptosis through suppressing bcl-2 expression, which provided potential therapeutic targets for zikv-associated renal diseases. |
2020-10-05 |
2023-08-13 |
mouse |
| Elnaz Hajipour, Farideh Jalali Mashayekhi, Ghasem Mosayebi, Maryam Baazm, Adib Zendede. Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model. Iranian journal of basic medical sciences. vol 21. issue 2. 2020-10-01. PMID:29456821. |
resveratrol decreases apoptosis and nlrp3 complex expressions in experimental varicocele rat model. |
2020-10-01 |
2023-08-13 |
rat |
| Elnaz Hajipour, Farideh Jalali Mashayekhi, Ghasem Mosayebi, Maryam Baazm, Adib Zendede. Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model. Iranian journal of basic medical sciences. vol 21. issue 2. 2020-10-01. PMID:29456821. |
due to the important role of antioxidant in decreasing the testis tissue damage, in this study we investigated the protective effect of resveratrol (res) on nlrp3 complex and apoptosis in experimental varicocele rats. |
2020-10-01 |
2023-08-13 |
rat |
| Richard E Kas. Inhibiting the NLRP3 Inflammasome With Methylene Blue as Treatment Adjunct in Myelodysplasia. Frontiers in oncology. vol 8. 2020-10-01. PMID:30101125. |
if as in rodents, methylene blue also inhibits nlrp3 inflammasome function in human myelodysplasia a trial of adjunctive methylene blue treatment in transfusion dependent, low risk myelodysplasia where marrow inflammation and apoptosis predominates, would be worth trying. |
2020-10-01 |
2023-08-13 |
human |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
mirna-223-3p regulates nlrp3 to promote apoptosis and inhibit proliferation of hep3b cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
the present study was performed to investigate the role of mir-223 in the proliferation and apoptosis of hcc cells through regulating nlrp3. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
mir-223 inhibited hcc cell proliferation and promoted apoptosis by directly targeting nlrp3. |
2020-09-30 |
2023-08-13 |
Not clear |
| Bour-Jr Wang, Hui-Wen Chiu, Yong-Lin Lee, Chia-Yi Li, Ying-Jan Wang, Yu-Hsuan Le. Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation. Journal of clinical medicine. vol 7. issue 12. 2020-09-30. PMID:30486377. |
pterostilbene attenuates hexavalent chromium-induced allergic contact dermatitis by preventing cell apoptosis and inhibiting il-1β-related nlrp3 inflammasome activation. |
2020-09-30 |
2023-08-13 |
mouse |
| Bour-Jr Wang, Hui-Wen Chiu, Yong-Lin Lee, Chia-Yi Li, Ying-Jan Wang, Yu-Hsuan Le. Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation. Journal of clinical medicine. vol 7. issue 12. 2020-09-30. PMID:30486377. |
furthermore, our current findings demonstrated that the nlrp3 inflammasome could be involved in the cr(vi)-mediated inflammation and apoptosis of acd. |
2020-09-30 |
2023-08-13 |
mouse |
| Xiao Bi, Jingjing Wang, Yuqing Liu, Yingdeng Wang, Wei Din. MnTBAP treatment ameliorates aldosterone-induced renal injury by regulating mitochondrial dysfunction and NLRP3 inflammasome signalling. American journal of translational research. vol 10. issue 11. 2020-09-30. PMID:30662603. |
in addition, mntbap treatment of aldosterone-infused mice significantly improved mitochondrial morphology and function, suppressed the activation of nlrp3 inflammasome, reduced renal tubular cell apoptosis, decreased phenotypic alterations, and ameliorated renal apoptosis. |
2020-09-30 |
2023-08-13 |
mouse |
| Benjamin Demarco, Kaiwen W Chen, Petr Bro. Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation. Molecular & cellular oncology. vol 6. issue 4. 2020-09-29. PMID:31211242. |
pannexin-1 channels bridge apoptosis to nlrp3 inflammasome activation. |
2020-09-29 |
2023-08-13 |
Not clear |