| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shih-Che Hung, Lu-Chu Ke, Te-Sheng Lien, Hsuan-Shun Huang, Der-Shan Sun, Chia-Liang Cheng, Hsin-Hou Chan. Nanodiamond-Induced Thrombocytopenia in Mice Involve P-Selectin-Dependent Nlrp3 Inflammasome-Mediated Platelet Aggregation, Pyroptosis and Apoptosis. Frontiers in immunology. vol 13. 2022-04-21. PMID:35444640. |
nanodiamond-induced thrombocytopenia in mice involve p-selectin-dependent nlrp3 inflammasome-mediated platelet aggregation, pyroptosis and apoptosis. |
2022-04-21 |
2023-08-13 |
mouse |
| Wei Zhang, Qi Zh. Punicalagin suppresses inflammation in ventilator-induced lung injury through PAR2 inhibition-induced inhibition of NLRP3 inflammasome activation. Chemical biology & drug design. 2022-04-18. PMID:35434894. |
the levels of inflammatory cytokines (tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6), par2, nlr family pyrin domain containing-3 (nlrp3) and apoptosis associated speck-like protein containing a card (asc) in the balf lungs or cells were analyzed by enzyme-linked immune-sorbent assay (elisa), qrt-pcr or/and western blot. |
2022-04-18 |
2023-08-13 |
mouse |
| Hui Kong, Hongran Zhao, Tianran Chen, Yanling Song, Yan Cu. Targeted P2X7/NLRP3 signaling pathway against inflammation, apoptosis, and pyroptosis of retinal endothelial cells in diabetic retinopathy. Cell death & disease. vol 13. issue 4. 2022-04-12. PMID:35410316. |
the expression of inflammasome-related proteins p2x7 and nlrp3, and apoptosis in the retinas of 3tc-treated diabetic mice were compared to those of untreated diabetic mice. |
2022-04-12 |
2023-08-13 |
mouse |
| Zi-Tan Peng, Hui Li. Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial cells by repressing NLRP3 inflammasome-mediated apoptosis. Toxicology in vitro : an international journal published in association with BIBRA. 2022-03-25. PMID:35331853. |
puerarin attenuates lps-induced inflammatory injury in gastric epithelial cells by repressing nlrp3 inflammasome-mediated apoptosis. |
2022-03-25 |
2023-08-13 |
Not clear |
| Zi-Tan Peng, Hui Li. Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial cells by repressing NLRP3 inflammasome-mediated apoptosis. Toxicology in vitro : an international journal published in association with BIBRA. 2022-03-25. PMID:35331853. |
puerarin ameliorated lps-induced cytotoxicity and apoptosis, while repressing lps-stimulated nlrp3 inflammasome-mediated pyroptosis in ges-1 cells, as evidenced by significantly decreased expression of nlrp3, asc, cleaved caspase-1, il-1β and il-18. |
2022-03-25 |
2023-08-13 |
Not clear |
| Zi-Tan Peng, Hui Li. Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial cells by repressing NLRP3 inflammasome-mediated apoptosis. Toxicology in vitro : an international journal published in association with BIBRA. 2022-03-25. PMID:35331853. |
our findings suggest that puerarin may ameliorate lps-induced inflammatory injury in ges-1 cells by activating the ampk/sirt1 signaling pathway and thereby repressing nlrp3 inflammasome-mediated apoptosis. |
2022-03-25 |
2023-08-13 |
Not clear |
| Yamei Li, Bo Peng, Yi Li, Airu Huang, Yinian Peng, Qian Yu, Yufeng L. MiR-203a-3p/153-3p improves cognitive impairments induced by ischemia/reperfusion via blockade of SRC-mediated MAPK signaling pathway in ischemic stroke. Chemico-biological interactions. 2022-03-20. PMID:35305977. |
moreover, mir-203a-3p and mir-153-3p relieved the apoptosis, decreases nlrp3 inflammasome activity, decreases oxidative stress and inflammation in hippocampal neuron through targeting src. |
2022-03-20 |
2023-08-13 |
rat |
| Nadine A Kerr, Juliana Sanchez, Gregory O'Connor, Brant D Watson, Sylvia Daunert, Helen M Bramlett, W Dalton Dietric. Inflammasome-Regulated Pyroptotic Cell Death in Disruption of the Gut-Brain Axis After Stroke. Translational stroke research. 2022-03-20. PMID:35306629. |
we examined the time course of inflammasome protein expression in brain and intestinal lysate using western blot analysis at 1-, 3-, and 7-days post-injury for caspase-1, interleukin-1β, nod-like receptor protein 3 (nlrp3), and apoptosis speck-like protein containing a caspase-recruiting domain (asc) and gasdermin-d (gsdmd) cleavage. |
2022-03-20 |
2023-08-13 |
mouse |
| Wei He, Qian Wang, Weiping Sha, Liming Wang, Di Li, Gang Che. P2X4 Inhibition reduces microglia inflammation and apoptosis by NLRP3 and improves nervous system defects in rat brain trauma model. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 99. 2022-03-15. PMID:35290938. |
p2x4 inhibition reduces microglia inflammation and apoptosis by nlrp3 and improves nervous system defects in rat brain trauma model. |
2022-03-15 |
2023-08-13 |
rat |
| Wei He, Qian Wang, Weiping Sha, Liming Wang, Di Li, Gang Che. P2X4 Inhibition reduces microglia inflammation and apoptosis by NLRP3 and improves nervous system defects in rat brain trauma model. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 99. 2022-03-15. PMID:35290938. |
the inhibition of p2x4 effectively reduced the inflammation and apoptosis of microglia, and nlrp3 may be involved in this process. |
2022-03-15 |
2023-08-13 |
rat |
| Chunyan Bai, Yingfei Zhu, Qiaoliang Dong, Yuwei Zhan. Chronic intermittent hypoxia induces the pyroptosis of renal tubular epithelial cells by activating the NLRP3 inflammasome. Bioengineered. vol 13. issue 3. 2022-03-09. PMID:35263214. |
pyroptosis is a programmed mode of cell death following cell apoptosis and cell necrosis, which is mediated by nlrp3 signaling. |
2022-03-09 |
2023-08-13 |
rat |
| Min Shi, Jianqiang Wang, Fangfang Bi, Zhangyong Ba. Diosmetin alleviates cerebral ischemia-reperfusion injury through Keap1-mediated Nrf2/ARE signaling pathway activation and NLRP3 inflammasome inhibition. Environmental toxicology. 2022-02-22. PMID:35191607. |
in conclusion, diosmetin attenuated ogd/r-induced pc12 cell viability inhibition, apoptosis, oxidative stress and inflammation through keap1-mediated nrf2/are signaling activation and nlrp3 inflammasome inhibition, and alleviated cir-induced neurological injury in mcao rat model. |
2022-02-22 |
2023-08-13 |
rat |
| Jingyang Chen, Meiru Bian, Lingxiao Pan, Hanshi Yan. α-Mangostin protects lipopolysaccharide-stimulated nucleus pulposus cells against NLRP3 inflammasome-mediated apoptosis via the NF-κB pathway. Journal of applied toxicology : JAT. 2022-02-21. PMID:35187677. |
α-mangostin protects lipopolysaccharide-stimulated nucleus pulposus cells against nlrp3 inflammasome-mediated apoptosis via the nf-κb pathway. |
2022-02-21 |
2023-08-13 |
human |
| Jingyang Chen, Meiru Bian, Lingxiao Pan, Hanshi Yan. α-Mangostin protects lipopolysaccharide-stimulated nucleus pulposus cells against NLRP3 inflammasome-mediated apoptosis via the NF-κB pathway. Journal of applied toxicology : JAT. 2022-02-21. PMID:35187677. |
moreover, inhibition of nf-κb by pdtc aggravated the inhibitory effects of α-mangostin on nlrp3 inflammasome activation and apoptosis in lps-induced npcs. |
2022-02-21 |
2023-08-13 |
human |
| Jingyang Chen, Meiru Bian, Lingxiao Pan, Hanshi Yan. α-Mangostin protects lipopolysaccharide-stimulated nucleus pulposus cells against NLRP3 inflammasome-mediated apoptosis via the NF-κB pathway. Journal of applied toxicology : JAT. 2022-02-21. PMID:35187677. |
these findings suggested that α-mangostin exerted a protective effect on nlrp3 inflammasome-mediated apoptosis in lps-induced npcs through regulating nf-κb signaling. |
2022-02-21 |
2023-08-13 |
human |
| Zhongfen Liu, Shaohua Gao, Ying Bu, Xiaoyan Zhen. Luteolin Protects Cardiomyocytes Cells against Lipopolysaccharide-Induced Apoptosis and Inflammatory Damage by Modulating Nlrp3. Yonsei medical journal. vol 63. issue 3. 2022-02-20. PMID:35184424. |
luteolin protects cardiomyocytes cells against lipopolysaccharide-induced apoptosis and inflammatory damage by modulating nlrp3. |
2022-02-20 |
2023-08-13 |
Not clear |
| Shu-Hui Wang, Liu-Gen Cui, Xue-Ling Su, Sumra Komal, Rui-Cong Ni, Ming-Xi Zang, Li-Rong Zhang, Sheng-Na Ha. GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts. European journal of pharmacology. 2022-02-19. PMID:35182545. |
gsk-3β-mediated activation of nlrp3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts. |
2022-02-19 |
2023-08-13 |
rat |
| Shu-Hui Wang, Liu-Gen Cui, Xue-Ling Su, Sumra Komal, Rui-Cong Ni, Ming-Xi Zang, Li-Rong Zhang, Sheng-Na Ha. GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts. European journal of pharmacology. 2022-02-19. PMID:35182545. |
in this study, we show how gsk-3β-mediated activation of the nlrp3 inflammasome/caspase-1/il-1β pathway leads to apoptosis and pyroptosis of cardiomyocytes (cms) and cfs. |
2022-02-19 |
2023-08-13 |
rat |
| Shu-Hui Wang, Liu-Gen Cui, Xue-Ling Su, Sumra Komal, Rui-Cong Ni, Ming-Xi Zang, Li-Rong Zhang, Sheng-Na Ha. GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts. European journal of pharmacology. 2022-02-19. PMID:35182545. |
these data demonstrate that gsk-3β regulates apoptosis and pyroptosis of rcms and rcfs due to nlrp3 inflammasome activation in rcfs. |
2022-02-19 |
2023-08-13 |
rat |
| Yanji Zhu, Min Liu, Wenlong Xun, Keliang Li, Xiangji Ni. P2X7R antagonist protects against renal injury in mice with adriamycin nephropathy. Experimental and therapeutic medicine. vol 23. issue 2. 2022-01-24. PMID:35069842. |
the expression of il-1β, il-18, p2x7r, ox-ldl, cxcl16, bax, caspase-3 and nlrp3, as well as cellular apoptosis in the renal tissues of the adr group, was significantly increased in the adr group compared with the control. |
2022-01-24 |
2023-08-13 |
mouse |