| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pravin S Uttekar, Vishal D Yadav, Durgacharan A Bhagwa. 1, 2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamin (DPPE), doxorubicin and folic acid conjugated micelles for cancer management in tumor bearing BALB/c mice. Bioorganic & medicinal chemistry letters. vol 50. 2021-11-22. PMID:34438013. |
in-vitro anticancer activity and apoptosis assay was evaluated in breast cancer (mcf-7) cells using mtt assay and flow cytometer respectively. |
2021-11-22 |
2023-08-13 |
mouse |
| Qiang Li, Peilan Zhang, Yun Ca. Genkwanin suppresses MPP Neurotoxicology. vol 87. 2021-11-22. PMID:34481870. |
cell viability, lactate dehydrogenase (ldh) release, caspase-3/7 activity, and apoptosis was evaluated by mtt, ldh release assay, caspase-3/7 activity assay, and tunel assay, respectively. |
2021-11-22 |
2023-08-13 |
Not clear |
| Yi-Nan Liu, Yu-Dong Mu, Hui Wang, Meng Zhang, Ya-Wen Shi, Ge Mi, Lei-Xuan Peng, Jing-Hong Che. Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis. Toxicology. vol 464. 2021-11-22. PMID:34673134. |
for the salubrinal protection assay, cells were pretreated with 20 μm salubrinal for 1 h, and treated with and without t-2 toxin for 24 h. the cell viability was determined using the mtt assay; and the cell apoptosis was determined using the flow cytometry assay; the mrna and protein levels of the ers markers and ecm were determined using rt-pcr and western blotting. |
2021-11-22 |
2023-08-13 |
rat |
| Chao Wang, Ruiling Zhao, Suhong Zhan. lncRNA XIST knockdown suppresses cell proliferation and promotes apoptosis in diabetic cataracts through the miR‑34a/SMAD2 axis. Molecular medicine reports. vol 25. issue 1. 2021-11-22. PMID:34751414. |
mtt, transwell, wound healing and tunel assays were performed to examine cell proliferation, invasion, migration and apoptosis, respectively. |
2021-11-22 |
2023-08-13 |
Not clear |
| Wenhao Yao, Xu Qian, Sebastian Ochsenreither, Ferrone Soldano, Albert B DeLeo, Holger Sudhoff, Felix Oppel, Andreas Kuppig, Konrad Klinghammer, Andreas M Kaufmann, Andreas E Alber. Disulfiram Acts as a Potent Radio-Chemo Sensitizer in Head and Neck Squamous Cell Carcinoma Cell Lines and Transplanted Xenografts. Cells. vol 10. issue 3. 2021-11-19. PMID:33671083. |
cell viability was assessed by the 1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan (mtt) and apoptosis assays, and the cell cycle and reactive oxygen species (ros) levels were evaluated by fluorescence-activated cell sorting (facs). |
2021-11-19 |
2023-08-13 |
Not clear |
| Yutaka Hashimoto, Marisa Shiina, Shigekatsu Maekawa, Taku Kato, Varahram Shahryari, Priyanka Kulkarni, Pritha Dasgupta, Soichiro Yamamura, Sharanjot Saini, Z Laura Tabatabai, Rajvir Dahiya, Yuichiro Tanak. Suppressor effect of catechol-O-methyltransferase gene in prostate cancer. PloS one. vol 16. issue 9. 2021-11-19. PMID:34587154. |
re-expression of comt led to suppressed migration ability (wound healing assay) and enhanced apoptosis (flow cytometric analyses), and when challenged with 4-hydroxyestradiol, a marked reduction of cell proliferation (mtt assay) was observed. |
2021-11-19 |
2023-08-13 |
mouse |
| Zhiwei Xu, Xiaojian Liu, Daoping Zhuan. Artesunate inhibits cell proliferation, migration, and invasion of thyroid cancer by regulating the PI3K/AKT/FKHR pathway. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2021-11-19. PMID:34797728. |
we determined the effect of artesunate on the proliferation of thyroid cancer cells using the mtt assay, cell colony formation experiments, and western blotting, and used flow cytometry to detect the apoptosis of cancer cells. |
2021-11-19 |
2023-08-13 |
Not clear |
| Koujun Zhu, Jun Zhu, Jichun Geng, Yongjian Zhang, Yan Qin, Fudong Wang, Yuan Wen. circSNX6 (hsa_circ_0031608) enhances drug resistance of non-small cell lung cancer (NSCLC) via miR-137. Biochemical and biophysical research communications. vol 567. 2021-11-18. PMID:34144504. |
mtt, cell colony formation and tunel assays were utilized to assess cell viability, proliferation, apoptosis, respectively. |
2021-11-18 |
2023-08-13 |
Not clear |
| Dingrui Nie, Ping Ma, Yanli Chen, Huayan Zhao, Lin Liu, Dao Xin, Weijie Cao, Fang Wang, XiaoLi Meng, Linxiang Liu, Menghan Xie, Ling Su. MiR-204 suppresses the progression of acute myeloid leukemia through HGF/c-Met pathway. Hematology (Amsterdam, Netherlands). vol 26. issue 1. 2021-11-18. PMID:34789086. |
the viability, cell cycle, apoptosis, migration, and invasion were analyzed by mtt, flow cytometry, and transwell assays. |
2021-11-18 |
2023-08-13 |
Not clear |
| Ling-Bin Xu, Jie Xiong, Ya-Hui Zhang, Yun Dai, Xiao-Ping Ren, Ya-Juan Ren, Dong Han, Sheng-Hong Wei, Min Q. miR‑205‑3p promotes lung cancer progression by targeting APBB2. Molecular medicine reports. vol 24. issue 2. 2021-11-17. PMID:34165160. |
it was found that lentivirus mediated‑apbb2 knockdown could promote cellular viability and suppress apoptosis in nsclc cells, as determined via mtt, tunel and flow cytometry assays. |
2021-11-17 |
2023-08-13 |
Not clear |
| Xueying Tong, Jiajuan Chen, Wei Liu, Hui Liang, Hezhong Zh. LncRNA LSINCT5/miR-222 regulates myocardial ischemia‑reperfusion injury through PI3K/AKT pathway. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-17. PMID:34184201. |
the effects of lsinct5 on cell viability and apoptosis were detected by mtt and flow cytometry, respectively. |
2021-11-17 |
2023-08-13 |
Not clear |
| Zahra Habibi-Kelishomi, Bahram Goliaei, Alireza Nikoofa. Butein combined with radiotherapy enhances radioresponse of gastric cancer cell by impairing DNA damage repair. Biochemical and biophysical research communications. vol 570. 2021-11-17. PMID:34271434. |
to evaluate the radiosensitizing effect of butein, we used mkn-45 cell line and performed several assays such as mtt, soft-agar colony formation, apoptosis, cell cycle, and comet assays. |
2021-11-17 |
2023-08-13 |
Not clear |
| Peng-Cheng Zhao, Shao-Nian Xu, Zhen-Shan Huang, Guo-Wei Jiang, Peng-Cheng Deng, Yong-Ming Zhan. Hyperbaric oxygen via mediating SIRT1-induced deacetylation of HMGB1 improved cReperfusion inj/reperfusion injury. The European journal of neuroscience. vol 54. issue 9. 2021-11-17. PMID:34523745. |
cell proliferation was detected using mtt, and apoptosis was determined by flow cytometry. |
2021-11-17 |
2023-08-13 |
mouse |
| Zhenyu Xu, Junjie Sun, Yang Chen, Ting Zhang, Yan Qin, Dong Hu. HIG1 domain family member 1A disrupts proliferation, migration and invasion of colon adenocarcinoma cells. Bioengineered. 2021-11-17. PMID:34787061. |
mtt assays, colony formation assay, cell cycle analysis, annexin v-fitc/pi, wound-healing analysis, and transwell assay were used to test cell proliferation, formation of cell colonies, cell cycle progression, migration, invasiveness, and apoptosis. |
2021-11-17 |
2023-08-13 |
human |
| Ruixiang Li, Jiahua Hu, Sue Ca. The Clinical Significance of miR-135b-5p and Its Role in the Proliferation and Apoptosis of Hippocampus Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 42. issue 5-6. 2021-11-16. PMID:33596573. |
mtt assay and flow cytometric apoptosis assay were conducted to evaluate the effects of mir-135b-5p on cell viability and apoptosis. |
2021-11-16 |
2023-08-13 |
rat |
| Yu Cui, Yi Zheng, Yue Lu, Muyuan Zhang, Lei Yang, Wei L. LINC01224 facilitates the proliferation and inhibits the radiosensitivity of melanoma cells through the miR-193a-5p/NR1D2 axis. The Kaohsiung journal of medical sciences. 2021-11-16. PMID:34783160. |
the effects of linc01224 on cell proliferation and apoptosis in melanoma were assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), colony formation, and flow cytometry assays. |
2021-11-16 |
2023-08-13 |
Not clear |
| Zhenduo Zhang, Jinbo He, Baoliang Wan. Circular RNA circ_HECTD1 regulates cell injury after cerebral infarction by miR-27a-3p/FSTL1 axis. Cell cycle (Georgetown, Tex.). vol 20. issue 9. 2021-11-15. PMID:33843447. |
cell proliferative ability and apoptosis were assessed by 5-ethynyl-2'-deoxyuridine (edu), 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt), and flow cytometry assays. |
2021-11-15 |
2023-08-13 |
Not clear |
| Yan-Yan Zhang, Gao-Yun Xiong, Xiao-Xing Xi. MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells. Bioscience reports. vol 41. issue 6. 2021-11-15. PMID:33942856. |
mirna mimics or inhibitor-mediated up- or down-regulation of indicated mirna was applied to characterize the biological effects of mir-222 using mtt, apoptosis and dna damage assay. |
2021-11-15 |
2023-08-13 |
human |
| Zhensong Jiang, Jianru Zhan. Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway. Cell cycle (Georgetown, Tex.). vol 20. issue 10. 2021-11-15. PMID:33945431. |
furthermore, lps-induced pc12 cells were established and incubated with dil-labeled msc-exs to explore their effects on cell viability, apoptosis and inflammation through mtt, flow cytometry and elisa, respectively. |
2021-11-15 |
2023-08-13 |
rat |
| Jinpeng Zhong, Bin Cheng, Li Yang, Guanlan Li, Yunzhong Yuan, Gang Luo, Zhiping Shu, Hong Jian. LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/HDAC9 axis. Central-European journal of immunology. vol 46. issue 3. 2021-11-13. PMID:34764804. |
the proliferation and apoptosis were determined by mtt and annexin v/pi double-staining assay, respectively. |
2021-11-13 |
2023-08-13 |
Not clear |