| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emma Rodriguez, Guangsheng Pei, Sang T Kim, Alexis German, Prema Robinso. Substance P Antagonism as a Novel Therapeutic Option to Enhance Efficacy of Cisplatin in Triple Negative Breast Cancer and Protect PC12 Cells against Cisplatin-Induced Oxidative Stress and Apoptosis. Cancers. vol 13. issue 15. 2021-10-23. PMID:34359773. |
we determined that treatment with aprepitant, an sp-receptor antagonist decreased cisplatin-induced, loss of viability (studied by mtt assay), production of reactive oxygen species (by dcfda assay) and apoptosis (by flow-cytometry) in pc12 cells while it was increased in the two tnbc cells. |
2021-10-23 |
2023-08-13 |
Not clear |
| Wang Jun, Ouyang Shaobo, Zhang Xianhua, Zhao Siyu, Cheng Mingyang, Fan Xin, Cai Ying, Liao La. Deregulation of hsa_circ_0001971/miR-186 and hsa_circ_0001874/miR-296 signaling pathways promotes the proliferation of oral squamous carcinoma cells by synergistically activating SHP2/PLK1 signals. Scientific reports. vol 11. issue 1. 2021-10-23. PMID:34663837. |
mtt assay and fcm assay were performed to investigate the synergistic effect of circ_0001971 and circ_0001874 on cell proliferation and apoptosis. |
2021-10-23 |
2023-08-13 |
Not clear |
| Qingshan Ji, Jing Han, Lisong Wang, Jiajia Liu, Yiran Dong, Kai Zhu, Lei Sh. MicroRNA-34a promotes apoptosis of retinal vascular endothelial cells by targeting SIRT1 in rats with diabetic retinopathy. Cell cycle (Georgetown, Tex.). vol 19. issue 21. 2021-10-22. PMID:33064974. |
mtt assay and flow cytometry were performed to detect proliferation and apoptosis. |
2021-10-22 |
2023-08-13 |
rat |
| Bo Qin, Meng Dong, Zhengyang Wang, Jiajia Wan, Yingying Xie, Yi Jiao, Dan Ya. Long non‑coding RNA CASC15 facilitates esophageal squamous cell carcinoma tumorigenesis via decreasing SIM2 stability via FTO‑mediated demethylation. Oncology reports. vol 45. issue 3. 2021-10-22. PMID:33650646. |
cell proliferation and apoptosis were evaluated via mtt, flow cytometry and caspase‑3 activity assays, respectively. |
2021-10-22 |
2023-08-13 |
mouse |
| Lu Chang, Rui Zhou, Yihan He, Mei Meng, Jinhang Hu, Yanru Liu, Yalei Pan, Zhishu Tang, Zhenggang Yu. Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell. Molecular medicine reports. vol 24. issue 2. 2021-10-22. PMID:34080021. |
the effect of rpmtg on the proliferation, cell cycle progression and apoptosis of hct116 and sw620 cells were detected by mtt, flow cytometry and western blotting assays, and it was demonstrated that rpmtg could inhibit the proliferation of hct116 and sw620 cells with ic50 values of 315.8 and 355.1 |
2021-10-22 |
2023-08-13 |
Not clear |
| Chenguang Bai, Xiaohong Liu, Jian-Ming Zheng, Cen Qiu, Yan Zhu, Jingjing Xu, Jing Zhao, Dalie M. A novel PDGFRA mutation in gastrointestinal stromal tumours, L839P, is sensitive to imatinib in vitro. Oncology letters. vol 3. issue 5. 2021-10-21. PMID:22783407. |
the responses of cells with pdgfra(wild), pdgfra(l839p) and pdgfra(d842v) mutants to imatinib were determined by methyl thiazolyl tetrazolium (mtt) assay, western blotting and apoptosis assays. |
2021-10-21 |
2023-08-12 |
Not clear |
| Nannan Tong, Jie Zhang, Youran Chen, Zhubo Li, Yonghuang Luo, Hua Zuo, Xiaoyan Zha. Berberine sensitizes mutliple human cancer cells to the anticancer effects of doxorubicin in vitro. Oncology letters. vol 3. issue 6. 2021-10-21. PMID:22783430. |
the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-tetrazolium bromide (mtt) assay was used to detect the cell viability of a549, hela and hepg2 cells after each cell line was treated with dox, ber or a combination of dox and ber for 24 h. apoptosis was evaluated by acridine orange staining. |
2021-10-21 |
2023-08-12 |
human |
| Dong Liang, Zehui Fang, Min Dong, Chao Liang, Chonghao Xing, Juan Zhao, Yiju Yan. Effect of RNA interference-related HiWi gene expression on the proliferation and apoptosis of lung cancer stem cells. Oncology letters. vol 4. issue 1. 2021-10-21. PMID:22807978. |
the conditions of lung cancer tsc proliferation and apoptosis in each group were examined using an mtt assay, fluorescence-activated cell sorting and annexin v staining. |
2021-10-21 |
2023-08-12 |
Not clear |
| Jun Chang, Wei Wang, Hui Zhang, Yong Hu, Zongsheng Yi. Bisphosphonates regulate cell proliferation, apoptosis and pro-osteoclastic expression in MG-63 human osteosarcoma cells. Oncology letters. vol 4. issue 2. 2021-10-21. PMID:22844373. |
the mtt assay showed that zol induced a distinct dose- and time-dependent reduction of cell viability with an ic(50) value of 52.37±1.0 μm for 72 h. flow cytometric analysis further revealed that the cell apoptosis was induced by arrest of the cell cycle in the g(1) phase. |
2021-10-21 |
2023-08-12 |
human |
| Chuan-Jiang Yu, Su-Juan Ye, Zhi-Hua Feng, Wen-Jing Ou, Xi-Kun Zhou, Ling-Dong Li, Yong-Qiu Mao, Wen Zhu, Yu-Quan We. Effect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells. Oncology letters. vol 1. issue 4. 2021-10-21. PMID:22966375. |
mtt assay and flow cytometry showed that fraxiparine slightly inhibited the cell viability dose- and time-dependently, but did not arrest the a549 cells in the g1 phase nor induce early apoptosis. |
2021-10-21 |
2023-08-12 |
human |
| Ying Chen, Yong Cao, Danlei Yang, Kaiyan Li, Zhengyun Wang, Jing Zhu, Hansvin Bunjhoo, Shengdao Xiong, Yongjian Xu, Weining Xion. Increase of the therapeutic effect on non-small-cell lung cancer cells with combination treatment of shRNA against Cyclin D1 and Bcl-xL in vitro. Experimental and therapeutic medicine. vol 3. issue 2. 2021-10-21. PMID:22969878. |
the apoptosis and proliferation of the two cell lines were evaluated by dimethylthiazol-diphenyltetrazolium bromide (mtt), cell count and flow cytometry. |
2021-10-21 |
2023-08-12 |
Not clear |
| Shigeto Matsushita, Ko-Ichi Tada, Ko-Ichi Kawahara, Kazuhiro Kawai, Teruto Hashiguchi, Ikuro Maruyama, Takuro Kanekur. Advanced malignant melanoma responds to Prunus mume Sieb. Et Zucc (Ume) extract: Case report and in vitro study. Experimental and therapeutic medicine. vol 1. issue 4. 2021-10-21. PMID:22993577. |
in vitro studies, mtt assay, flow cytometric cell cycle analysis and immunofluorescence microscopy revealed that mk615 inhibited the growth of sk-mel28 cells in a dose-dependent manner, increased the proportion of cells in sub-g1 phase and induced apoptosis. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yoshioki Shiraishi, Kumiko Gotoh, Tomomi Towata, Tatsuya Shimasaki, Shinya Suzu, Akihiro Kojima, Seiji Okad. Therapeutic effects of γ-irradiation in a primary effusion lymphoma mouse model. Experimental and therapeutic medicine. vol 1. issue 1. 2021-10-21. PMID:23136597. |
an mtt assay and trypan blue exclusion assay revealed that irradiation significantly suppressed cell proliferation in the pel cell lines in a dose-dependent manner, and induced apoptosis. |
2021-10-21 |
2023-08-12 |
mouse |
| Asaf Taghiyev, Deguang Sun, Zhen Ming Gao, Rui Liang, Liming Wan. Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway. Experimental and therapeutic medicine. vol 4. issue 4. 2021-10-21. PMID:23170120. |
the mtt method was used to determine cell viability, and flow cytometry was used to assess the rate of apoptosis and the changes in mitochondrial membrane potential; the cell cycle was also analyzed. |
2021-10-21 |
2023-08-12 |
human |
| Ting Liu, Dan Liu, Jing Liu, Ji-Tao Song, Shan-Ling Gao, Hui Li, Li-Hong Hu, Bing-Rong Li. Effect of NF-κB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29. Experimental and therapeutic medicine. vol 4. issue 4. 2021-10-21. PMID:23170132. |
cell morphology was observed using inverted microscopy, and cell viability and apoptosis were assessed using the mtt assay and flow cytometry, respectively. |
2021-10-21 |
2023-08-12 |
Not clear |
| Kunpeng Zhao, Yan'ge Wang, Xueyin Wang, Yugang Wang, Yuanfang M. Tagged and untagged TRAIL show different activity against tumor cells. Oncology letters. vol 4. issue 6. 2021-10-21. PMID:23205127. |
we compared the abilities of the proteins to bind to death receptor 5 (dr5) by elisa and to induce apoptosis in a normal liver cell line (chang liver) and a human t-lymphocyte leukemia cell line (jurkat) by mtt assay, gr staining and facs. |
2021-10-21 |
2023-08-12 |
human |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
in vitro, a549 human lung adenocarcinoma cells were treated with ns, lip-null, etoposide, lip-pvax-m or lip-phtert-m, and examined for cell viability through mtt assays or for apoptosis by flow cytometry and tunel assays. |
2021-10-21 |
2023-08-12 |
mouse |
| Ling Liu, Liansheng Gong, Yangde Zhang, Nianfeng L. Glycolysis in Panc-1 human pancreatic cancer cells is inhibited by everolimus. Experimental and therapeutic medicine. vol 5. issue 1. 2021-10-21. PMID:23251295. |
cell proliferation and apoptosis were evaluated by mtt and flow cytometric analyses. |
2021-10-21 |
2023-08-12 |
human |
| Xiao-Man Xu, Yi Zhang, Dan Qu, Hong-Bo Liu, Xiu Gu, Guang-Yu Jiao, Li Zha. Combined anticancer activity of osthole and cisplatin in NCI-H460 lung cancer cells in vitro. Experimental and therapeutic medicine. vol 5. issue 3. 2021-10-21. PMID:23404433. |
to determine whether osthole enhances the anticancer effect of cisplatin in human lung cancer, we treated nci-h460 cells with osthole alone or in combination with cisplatin and evaluated cell growth and apoptosis using 3-(4,5-dimethyl thiazol-2yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry and fluorescence microscopy. |
2021-10-21 |
2023-08-12 |
human |
| Yu Gu, Shen-Lin Liu, Wen-Zheng Ju, Chang-Yin Li, Peng Ca. Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells. Oncology letters. vol 5. issue 2. 2021-10-21. PMID:23420047. |
in this study, cell viability and apoptosis of ragap-treated sw480 cells was evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry and 4',6-diamidino-2-phenylindole (dapi) staining. |
2021-10-21 |
2023-08-12 |
human |