| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhenyu Xu, Junjie Sun, Yang Chen, Ting Zhang, Yan Qin, Dong Hu. HIG1 domain family member 1A disrupts proliferation, migration and invasion of colon adenocarcinoma cells. Bioengineered. 2021-11-17. PMID:34787061. |
mtt assays, colony formation assay, cell cycle analysis, annexin v-fitc/pi, wound-healing analysis, and transwell assay were used to test cell proliferation, formation of cell colonies, cell cycle progression, migration, invasiveness, and apoptosis. |
2021-11-17 |
2023-08-13 |
human |
| Ruixiang Li, Jiahua Hu, Sue Ca. The Clinical Significance of miR-135b-5p and Its Role in the Proliferation and Apoptosis of Hippocampus Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 42. issue 5-6. 2021-11-16. PMID:33596573. |
mtt assay and flow cytometric apoptosis assay were conducted to evaluate the effects of mir-135b-5p on cell viability and apoptosis. |
2021-11-16 |
2023-08-13 |
rat |
| Yu Cui, Yi Zheng, Yue Lu, Muyuan Zhang, Lei Yang, Wei L. LINC01224 facilitates the proliferation and inhibits the radiosensitivity of melanoma cells through the miR-193a-5p/NR1D2 axis. The Kaohsiung journal of medical sciences. 2021-11-16. PMID:34783160. |
the effects of linc01224 on cell proliferation and apoptosis in melanoma were assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), colony formation, and flow cytometry assays. |
2021-11-16 |
2023-08-13 |
Not clear |
| Zhenduo Zhang, Jinbo He, Baoliang Wan. Circular RNA circ_HECTD1 regulates cell injury after cerebral infarction by miR-27a-3p/FSTL1 axis. Cell cycle (Georgetown, Tex.). vol 20. issue 9. 2021-11-15. PMID:33843447. |
cell proliferative ability and apoptosis were assessed by 5-ethynyl-2'-deoxyuridine (edu), 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt), and flow cytometry assays. |
2021-11-15 |
2023-08-13 |
Not clear |
| Yan-Yan Zhang, Gao-Yun Xiong, Xiao-Xing Xi. MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells. Bioscience reports. vol 41. issue 6. 2021-11-15. PMID:33942856. |
mirna mimics or inhibitor-mediated up- or down-regulation of indicated mirna was applied to characterize the biological effects of mir-222 using mtt, apoptosis and dna damage assay. |
2021-11-15 |
2023-08-13 |
human |
| Zhensong Jiang, Jianru Zhan. Mesenchymal stem cell-derived exosomes containing miR-145-5p reduce inflammation in spinal cord injury by regulating the TLR4/NF-κB signaling pathway. Cell cycle (Georgetown, Tex.). vol 20. issue 10. 2021-11-15. PMID:33945431. |
furthermore, lps-induced pc12 cells were established and incubated with dil-labeled msc-exs to explore their effects on cell viability, apoptosis and inflammation through mtt, flow cytometry and elisa, respectively. |
2021-11-15 |
2023-08-13 |
rat |
| Jinpeng Zhong, Bin Cheng, Li Yang, Guanlan Li, Yunzhong Yuan, Gang Luo, Zhiping Shu, Hong Jian. LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/HDAC9 axis. Central-European journal of immunology. vol 46. issue 3. 2021-11-13. PMID:34764804. |
the proliferation and apoptosis were determined by mtt and annexin v/pi double-staining assay, respectively. |
2021-11-13 |
2023-08-13 |
Not clear |
| Xin Li, Yimeng Lei, Ziyu Gao, Gang Wu, Wei Gao, Liping Xia, Jing Lu, Hui She. IL-34 affects fibroblast-like synoviocyte proliferation, apoptosis and function by regulating IL-17. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:34385542. |
in this study, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry of annexin v and pi staining were performed to assess cell proliferation and apoptosis progression in ra-flss after stimulated with increasing concentrations of il-34, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Tongyin Zhang, Daofei Ji, Junyi Sun, Jiangling Song, Limin Nie, Na Su. NPAS4 suppresses propofol-induced neurotoxicity by inhibiting autophagy in hippocampal neuronal cells. Archives of biochemistry and biophysics. vol 711. 2021-11-12. PMID:34418347. |
cell viability, lactate dehydrogenase (ldh) release, caspase-3 activity, and apoptosis were evaluated by mtt, a ldh-cytotoxicity assay kit, a caspase-3 colorimetric assay kit, and tunel assay, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Kun Ma, Chuan Zhang, Wuyin L. Fascin1 mediated release of pro-inflammatory cytokines and invasion/migration in rheumatoid arthritis via the STAT3 pathway. Cell cycle (Georgetown, Tex.). vol 20. issue 21. 2021-11-12. PMID:34499588. |
functional analysis contained mtt assay, flow cytometry,transwell™ assays, wound healing, quantitative polymerase chain reaction and western blotting were used to detect cell proliferation,apoptosis ratio, invasion/ migration, the mrna and protein expression of the realted markers, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Xiaohui Xu, Yong Wu, Ke Yi, Yan Hu, Weiqun Ding, Chungen Xin. IRF1 regulates the progression of colorectal cancer via interferon‑induced proteins. International journal of molecular medicine. vol 47. issue 6. 2021-11-11. PMID:33907823. |
mtt, 5‑ethynyl‑20‑deoxyuridine, colony formation, cell cycle alteration and apoptosis assays were performed in crc cell lines. |
2021-11-11 |
2023-08-13 |
mouse |
| Xinyan Ma, Ying Zhang, Mingyang Guan, Weidong Zhang, Huifang Tian, Caixiao Jiang, Xiaoxin Tan, Weijun Kan. Genotoxicity of chloroacetamide herbicides and their metabolites International journal of molecular medicine. vol 47. issue 6. 2021-11-11. PMID:33907828. |
the effects of ac, cmepa and mea on dna breakage, mapk/erk pathway activity, viability and apoptosis of hepg2 cells were examined by comet assay, western blotting, mtt assay and flow cytometry, respectively. |
2021-11-11 |
2023-08-13 |
zebrafish |
| Grzegorz Adamczuk, Ewelina Humeniuk, Magdalena Iwan, Dorota Natorska-Chomicka, Kamila Adamczuk, Agnieszka Korga-Plewk. The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line. Molecules (Basel, Switzerland). vol 26. issue 18. 2021-11-11. PMID:34577124. |
the cytotoxic effect of teriflunomide-an active metabolite of leflunomide-was determined using mtt assay, apoptosis detection, and cell cycle analysis. |
2021-11-11 |
2023-08-13 |
Not clear |
| Xiangyu Cao, Chengying Liu, Mengmeng Zhang, Ruochen Bi, Mingyang Fu, Elena Korik, Jiahe Chen, Jianyun Gao, Igor Semak, Jianli Li. Bovine lactoferrin and Lentinus edodes mycelia polysaccharide complex: The formation and the activity to protect islet β cells. International journal of biological macromolecules. vol 191. 2021-11-11. PMID:34592222. |
cell viability, reactive oxygen species (ros) level, apoptosis and the related signaling pathways were detected with thiazolyl blue tetrazolium bromide (mtt) assay, 2,7-dichlorofluorescin diacetate (dcfh-da) staining, hoechst 33258 staining and western blot methods respectively. |
2021-11-11 |
2023-08-13 |
cattle |
| Yu Zhou, Xiaohong Li, Yaju Duan, Yong Luo, Shuling Tang, Jian Wan. LncRNA MALAT-1 regulates the growth of interleukin-22-stimulated keratinocytes via the miR-330-5p/S100A7 axis. Autoimmunity. 2021-11-11. PMID:34761722. |
cell proliferation, inflammation, and apoptosis were detected by the mtt assay, western blotting, and flow cytometry analysis, respectively. |
2021-11-11 |
2023-08-13 |
Not clear |
| Rakshanaa R, Mohiraa Shafreen, Nitin Kuma. Inhibition of Proliferation in Ovarian Cancer Cell Line (PA-1) by the Action of Green Compound "Betanin". Applied biochemistry and biotechnology. 2021-11-11. PMID:34762269. |
determination of ic50 values through mtt assay was carried out, in addition measurement of mitochondrial membrane potential (mmp), effect of reactive oxygen species (ros) generation, and induction of apoptosis in ovarian cancer cells through betanin was also observed. |
2021-11-11 |
2023-08-13 |
Not clear |
| Dan Zou, Jin Bai, Enting Lu, Chunjiao Yang, Jiaqing Liu, Zhenpeng Wen, Xuqin Liu, Zi Jin, Mengdan Xu, Lei Jiang, Ye Zhang, Yi Zhan. Identification of Novel Drug Candidate for Epithelial Ovarian Cancer Frontiers in oncology. vol 11. 2021-11-10. PMID:34745968. |
the cytotoxicity of drug candidates was assessed by mtt and colony formation analysis, the proteins coded by hub genes were detected by western blots, and apoptosis analysis was evaluated by flow cytometry. |
2021-11-10 |
2023-08-13 |
Not clear |
| Hua-Xia Xie, Zhi-Yuan Xu, Jia-Ning Tang, Yi-An DU, Ling Huang, Peng-Fei Yu, Xiang-Dong Chen. Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway. Experimental and therapeutic medicine. vol 10. issue 3. 2021-11-09. PMID:26622467. |
the mtt assay was used to measure the effects of huaier on the growth of the cells, while cell cycle distribution and apoptosis levels were analyzed using flow cytometry. |
2021-11-09 |
2023-08-13 |
human |
| Xiaolin Lin, Ting Han, Qing Xia, Jiujie Cui, Meng Zhuo, Yiyi Liang, Wenyu Su, Lisha Wang, Liwei Wang, Zebing Liu, Xiuying Xia. CHPF promotes gastric cancer tumorigenesis through the activation of E2F1. Cell death & disease. vol 12. issue 10. 2021-11-09. PMID:34564711. |
cultured gastric cancer cells and human gastric epithelial cell line ges1 were used to investigate the effects of shchpf and she2f1 on the development and progression of gastric cancer by mtt, western blotting, flow cytometry analysis of cell apoptosis, colony formation, transwell and gastric cancer xenograft mouse models, in vitro and in vivo. |
2021-11-09 |
2023-08-13 |
mouse |
| Xiaoping Pan, Xiaolv Hong, Sumei Li, Ping Meng, Feng Xia. METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner. Experimental & molecular medicine. vol 53. issue 1. 2021-11-08. PMID:33420414. |
cultured adr-resistant mcf-7 cells were assayed for their half maximal inhibitory concentration (ic50) values and apoptosis using an mtt assay and annexin v-fitc/pi-labeled flow cytometry, and the cells were then xenografted into nude mice. |
2021-11-08 |
2023-08-13 |
mouse |