| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xianbo Shen, Yun Chen, Jibin Li, Huaiyin Huang, Chuping Liu, Ning Zho. Identification of Circ_001569 as a Potential Biomarker in the Diagnosis and Prognosis of Pancreatic Cancer. Technology in cancer research & treatment. vol 20. 2021-11-23. PMID:33413045. |
the effects of circ_001569 on the proliferation, migration, invasion, and apoptosis of pc cells were assessed by mtt, wound healing, transwell invasion assays, and flow cytometric analysis, respectively. |
2021-11-23 |
2023-08-13 |
human |
| Gehad Lotfy, Yasmine M Abdel Aziz, Mohamed M Said, El Sayed H El Ashry, El Sayed H El Tamany, Marwa M Abu-Serie, Mohamed Teleb, Alexander Dömling, Assem Baraka. Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators. Bioorganic chemistry. vol 117. 2021-11-23. PMID:34794098. |
the nci-selected derivatives were screened for cytotoxic activities against normal fibroblasts, mda-mb 231, hepg-2, and caco-2 cells via mtt assay, subjected to mechanistic apoptosis studies for assessment of p53, bcl2, p21, and caspase 3/7 status, then evaluated for potential mdm2 inhibition utilizing mst assay. |
2021-11-23 |
2023-08-13 |
Not clear |
| T Kloskowski, K Szeliski, K Krzeszowiak, Z Fekner, Ł Kazimierski, A Jundziłł, T Drewa, M Pokrywczyńsk. Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment. Scientific reports. vol 11. issue 1. 2021-11-23. PMID:34799663. |
cytotoxicity of mumio was analysed in these cell lines via mtt and real-time cell growth assays as well via the assessment of the cytoskeleton, apoptosis, and cell cycle. |
2021-11-23 |
2023-08-13 |
Not clear |
| Sahar Sadegh-Nejadi, Reza Afrisham, Solaleh Emamgholipour, Pantea Izadi, Neda Eivazi, Behnoosh Tahbazlahafi, Maliheh Pakneja. Influence of plasma circulating exosomes obtained from obese women on tumorigenesis and tamoxifen resistance in MCF-7 cells. IUBMB life. vol 72. issue 9. 2021-11-22. PMID:32542981. |
for evaluating resistance to tamoxifen, the cell viability, apoptosis, and the p53 protein were evaluated using the mtt assay, flow cytometry, and western blot methods, respectively. |
2021-11-22 |
2023-08-13 |
Not clear |
| Seyed Ali Nabipoorashrafi, Navid Shomali, Leila Sadat-Hatamnezhad, Mahmoud Mahami-Oskouei, Javad Mahmoudi, Babak Sandoghchian Shotorbani, Morteza Akbari, Huaxi Xu, Siamak Sandoghchian Shotorban. miR-143 acts as an inhibitor of migration and proliferation as well as an inducer of apoptosis in melanoma cancer cells in vitro. IUBMB life. vol 72. issue 9. 2021-11-22. PMID:32687246. |
also, the role of mir-143 in the induction of apoptosis and inhibition of proliferation by flow cytometry and mtt was confirmed. |
2021-11-22 |
2023-08-13 |
human |
| Xin Wang, Youlu Lu, Zhouting Tuo, Huan Zhou, Ying Zhang, Zhangjun Cao, Longfei Peng, Dexin Yu, Liangkuan B. Role of SIRT1/AMPK signaling in the proliferation, migration and invasion of renal cell carcinoma cells. Oncology reports. vol 45. issue 6. 2021-11-22. PMID:33907836. |
transwell, mtt and flow cytometry apoptosis assays were performed to evaluate the migration, invasion, proliferation and early apoptosis level of rcc cells. |
2021-11-22 |
2023-08-13 |
human |
| Lili Du, Jiexian Jing, Yan Wang, Xiaoqin Xu, Ting Sun, Yanchun Shi, Weigang Wang, Baoguo Tian, Cunzhi Han, Xianwen Zhao, Huibo Chan. Knockdown of SASS6 reduces growth of MDA‑MB‑231 triple‑negative breast cancer cells through arrest of the cell cycle at the G2/M phase. Oncology reports. vol 45. issue 6. 2021-11-22. PMID:33907854. |
cell viability was determined using an mtt assay, and cell cycle distribution and apoptosis were measured using flow cytometry. |
2021-11-22 |
2023-08-13 |
Not clear |
| Pravin S Uttekar, Vishal D Yadav, Durgacharan A Bhagwa. 1, 2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamin (DPPE), doxorubicin and folic acid conjugated micelles for cancer management in tumor bearing BALB/c mice. Bioorganic & medicinal chemistry letters. vol 50. 2021-11-22. PMID:34438013. |
in-vitro anticancer activity and apoptosis assay was evaluated in breast cancer (mcf-7) cells using mtt assay and flow cytometer respectively. |
2021-11-22 |
2023-08-13 |
mouse |
| Qiang Li, Peilan Zhang, Yun Ca. Genkwanin suppresses MPP Neurotoxicology. vol 87. 2021-11-22. PMID:34481870. |
cell viability, lactate dehydrogenase (ldh) release, caspase-3/7 activity, and apoptosis was evaluated by mtt, ldh release assay, caspase-3/7 activity assay, and tunel assay, respectively. |
2021-11-22 |
2023-08-13 |
Not clear |
| Yi-Nan Liu, Yu-Dong Mu, Hui Wang, Meng Zhang, Ya-Wen Shi, Ge Mi, Lei-Xuan Peng, Jing-Hong Che. Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis. Toxicology. vol 464. 2021-11-22. PMID:34673134. |
for the salubrinal protection assay, cells were pretreated with 20 μm salubrinal for 1 h, and treated with and without t-2 toxin for 24 h. the cell viability was determined using the mtt assay; and the cell apoptosis was determined using the flow cytometry assay; the mrna and protein levels of the ers markers and ecm were determined using rt-pcr and western blotting. |
2021-11-22 |
2023-08-13 |
rat |
| Chao Wang, Ruiling Zhao, Suhong Zhan. lncRNA XIST knockdown suppresses cell proliferation and promotes apoptosis in diabetic cataracts through the miR‑34a/SMAD2 axis. Molecular medicine reports. vol 25. issue 1. 2021-11-22. PMID:34751414. |
mtt, transwell, wound healing and tunel assays were performed to examine cell proliferation, invasion, migration and apoptosis, respectively. |
2021-11-22 |
2023-08-13 |
Not clear |
| Wenhao Yao, Xu Qian, Sebastian Ochsenreither, Ferrone Soldano, Albert B DeLeo, Holger Sudhoff, Felix Oppel, Andreas Kuppig, Konrad Klinghammer, Andreas M Kaufmann, Andreas E Alber. Disulfiram Acts as a Potent Radio-Chemo Sensitizer in Head and Neck Squamous Cell Carcinoma Cell Lines and Transplanted Xenografts. Cells. vol 10. issue 3. 2021-11-19. PMID:33671083. |
cell viability was assessed by the 1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan (mtt) and apoptosis assays, and the cell cycle and reactive oxygen species (ros) levels were evaluated by fluorescence-activated cell sorting (facs). |
2021-11-19 |
2023-08-13 |
Not clear |
| Yutaka Hashimoto, Marisa Shiina, Shigekatsu Maekawa, Taku Kato, Varahram Shahryari, Priyanka Kulkarni, Pritha Dasgupta, Soichiro Yamamura, Sharanjot Saini, Z Laura Tabatabai, Rajvir Dahiya, Yuichiro Tanak. Suppressor effect of catechol-O-methyltransferase gene in prostate cancer. PloS one. vol 16. issue 9. 2021-11-19. PMID:34587154. |
re-expression of comt led to suppressed migration ability (wound healing assay) and enhanced apoptosis (flow cytometric analyses), and when challenged with 4-hydroxyestradiol, a marked reduction of cell proliferation (mtt assay) was observed. |
2021-11-19 |
2023-08-13 |
mouse |
| Zhiwei Xu, Xiaojian Liu, Daoping Zhuan. Artesunate inhibits cell proliferation, migration, and invasion of thyroid cancer by regulating the PI3K/AKT/FKHR pathway. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2021-11-19. PMID:34797728. |
we determined the effect of artesunate on the proliferation of thyroid cancer cells using the mtt assay, cell colony formation experiments, and western blotting, and used flow cytometry to detect the apoptosis of cancer cells. |
2021-11-19 |
2023-08-13 |
Not clear |
| Koujun Zhu, Jun Zhu, Jichun Geng, Yongjian Zhang, Yan Qin, Fudong Wang, Yuan Wen. circSNX6 (hsa_circ_0031608) enhances drug resistance of non-small cell lung cancer (NSCLC) via miR-137. Biochemical and biophysical research communications. vol 567. 2021-11-18. PMID:34144504. |
mtt, cell colony formation and tunel assays were utilized to assess cell viability, proliferation, apoptosis, respectively. |
2021-11-18 |
2023-08-13 |
Not clear |
| Dingrui Nie, Ping Ma, Yanli Chen, Huayan Zhao, Lin Liu, Dao Xin, Weijie Cao, Fang Wang, XiaoLi Meng, Linxiang Liu, Menghan Xie, Ling Su. MiR-204 suppresses the progression of acute myeloid leukemia through HGF/c-Met pathway. Hematology (Amsterdam, Netherlands). vol 26. issue 1. 2021-11-18. PMID:34789086. |
the viability, cell cycle, apoptosis, migration, and invasion were analyzed by mtt, flow cytometry, and transwell assays. |
2021-11-18 |
2023-08-13 |
Not clear |
| Ling-Bin Xu, Jie Xiong, Ya-Hui Zhang, Yun Dai, Xiao-Ping Ren, Ya-Juan Ren, Dong Han, Sheng-Hong Wei, Min Q. miR‑205‑3p promotes lung cancer progression by targeting APBB2. Molecular medicine reports. vol 24. issue 2. 2021-11-17. PMID:34165160. |
it was found that lentivirus mediated‑apbb2 knockdown could promote cellular viability and suppress apoptosis in nsclc cells, as determined via mtt, tunel and flow cytometry assays. |
2021-11-17 |
2023-08-13 |
Not clear |
| Xueying Tong, Jiajuan Chen, Wei Liu, Hui Liang, Hezhong Zh. LncRNA LSINCT5/miR-222 regulates myocardial ischemia‑reperfusion injury through PI3K/AKT pathway. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-17. PMID:34184201. |
the effects of lsinct5 on cell viability and apoptosis were detected by mtt and flow cytometry, respectively. |
2021-11-17 |
2023-08-13 |
Not clear |
| Zahra Habibi-Kelishomi, Bahram Goliaei, Alireza Nikoofa. Butein combined with radiotherapy enhances radioresponse of gastric cancer cell by impairing DNA damage repair. Biochemical and biophysical research communications. vol 570. 2021-11-17. PMID:34271434. |
to evaluate the radiosensitizing effect of butein, we used mkn-45 cell line and performed several assays such as mtt, soft-agar colony formation, apoptosis, cell cycle, and comet assays. |
2021-11-17 |
2023-08-13 |
Not clear |
| Peng-Cheng Zhao, Shao-Nian Xu, Zhen-Shan Huang, Guo-Wei Jiang, Peng-Cheng Deng, Yong-Ming Zhan. Hyperbaric oxygen via mediating SIRT1-induced deacetylation of HMGB1 improved cReperfusion inj/reperfusion injury. The European journal of neuroscience. vol 54. issue 9. 2021-11-17. PMID:34523745. |
cell proliferation was detected using mtt, and apoptosis was determined by flow cytometry. |
2021-11-17 |
2023-08-13 |
mouse |