| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mingjia Gu, Fang Yin, Yuening Qin, Yali Tian, Xinjie Xiu, Hanjing Shen, Jiebin Zh. Synergistic antitumor efficacy of PD-1-conjugated PTX- and ZSQ-loaded nanoliposomes against multidrug-resistant liver cancers. Drug delivery and translational research. 2022-01-15. PMID:35031972. |
terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) staining and reactive oxygen species (ros) analysis demonstrated that pd-pzlp triggered an excessive ros reaction and cell apoptosis compared with that of free ptx or zsq, which was also consistent with the cell antiproliferative effects in mtt assay. |
2022-01-15 |
2023-08-13 |
human |
| Mallikarjun Gundappa, Vijaya Anand Arumugam, Hsi-Lung Hsieh, Balamuralikrishnan Balasubramanian, Velayuthaprabhu Shanmuga. Expression of tissue factor and TF-mediated integrin regulation in HTR-8/SVneo trophoblast cells. Journal of reproductive immunology. vol 150. 2022-01-14. PMID:35030354. |
in addition, cell migration assays, mtt, and dapi were performed to examine migration, cytotoxicity and apoptosis effect of fviia. |
2022-01-14 |
2023-08-13 |
Not clear |
| Lekshmi Krishna, Sagar Nilawar, Murugeswari Ponnalagu, Murali Subramani, Chaitra Jayadev, Rohit Shetty, Kaushik Chatterjee, Debashish Da. Fiber Diameter Differentially Regulates Function of Retinal Pigment and Corneal Epithelial Cells on Nanofibrous Tissue Scaffolds. ACS applied bio materials. vol 3. issue 2. 2022-01-12. PMID:35019286. |
the molecular changes in the cells in response to the different fibers were analyzed by qrt-pcr, western blot, immunofluorescence, elisa, flow cytometry, mtt assay, and sem to assess properties such as proliferation, apoptosis, membrane potential, epithelial-mesenchymal transition, stem cell population, vegf-a secretion, differentiation, and metabolic status of the cells. |
2022-01-12 |
2023-08-13 |
human |
| Dong Zhao, Yueting Ho. Long non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) upregulates Cyclin T2 (CCNT2) in laryngeal papilloma through sponging miR-577/miR-1224-5p and blocking cell apoptosis. Bioengineered. vol 13. issue 1. 2022-01-11. PMID:35012431. |
q-pcr, mtt, edu and western blotting were performed to determine that lnc-neat1 facilitates lp cell proliferation and hinders cell apoptosis. |
2022-01-11 |
2023-08-13 |
Not clear |
| Dong Zhao, Yueting Ho. Long non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) upregulates Cyclin T2 (CCNT2) in laryngeal papilloma through sponging miR-577/miR-1224-5p and blocking cell apoptosis. Bioengineered. vol 13. issue 1. 2022-01-11. PMID:35012431. |
western blotting, mtt and edu were used to confirm that lnc-neat1 promoted lp cell proliferation and inhibited cell apoptosis through ccnt2. |
2022-01-11 |
2023-08-13 |
Not clear |
| Gang Wang, Yanan Wang, Qinzhi Yang, Chunrong Xu, Youkun Zheng, Liqun Wang, Jianbo Wu, Min Zeng, Mao Lu. Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo. Cell death & disease. vol 13. issue 1. 2022-01-11. PMID:35013107. |
cell viability and apoptosis were assessed by the mtt assay, tunel staining, and annexin v-fitc and propidium iodide double staining. |
2022-01-11 |
2023-08-13 |
Not clear |
| Peng Wang, Yuanjing Hu, Pengpeng Qu, Ying Zhao, Jing Liu, Jianguo Zhao, Beihua Kon. Protein tyrosine phosphatase receptor type Z1 inhibits the cisplatin resistance of ovarian cancer by regulating PI3K/AKT/mTOR signal pathway. Bioengineered. vol 13. issue 1. 2022-01-10. PMID:35001804. |
mtt experiment and flow cytometer indicated that overexpression of ptprz1 enhanced the ddp sensitivity of oc cells and promoted the cell apoptosis. |
2022-01-10 |
2023-08-13 |
Not clear |
| Nadeeya Mad-Adam, Thidarath Rattanaburee, Tanotnon Tanawattanasuntorn, Potchanapond Graidis. Effects of trans-(±)-kusunokinin on chemosensitive and chemoresistant ovarian cancer cells. Oncology letters. vol 23. issue 2. 2022-01-07. PMID:34992691. |
mtt, colony formation, apoptosis and multi-caspase assays were used to determine cytotoxicity, the ability of single cells to form colonies, induction of apoptosis and multi-caspase activity, respectively. |
2022-01-07 |
2023-08-13 |
Not clear |
| Xin-Yu Lu, Zhong-Ze Wang, Si-Cheng Wan, Er-Hu Zhao, Hong-Juan Cu. [Effects of tetrandrine on proliferation, migration, and invasion of glioblastoma cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994145. |
in this study, mtt and brdu assays were employed to detect the effect of tet on the proliferation of ln229 glioblastoma cells; flow cytometry was used to analyze the cycle distribution and apoptosis; plate cloning assay and soft agar colony formation assay were performed to study the colony formation ability of ln229 cells exposed to tet; scratch assay and transwell assay were conducted to detect the ability of migration and invasion; western blot was adopted to the exploration of the molecular mechanism. |
2022-01-07 |
2023-08-13 |
Not clear |
| Jikun Du, Daibo Song, Yuanhua Li, Jierong Liu, Xiaoman Huang, Baohong Li, Li L. Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K. Neurotoxicity research. 2022-01-07. PMID:34994954. |
saikosaponin-d pretreatment could ameliorate glutamate-induced cytotoxicity according to mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and depress apoptosis according to hoechst 33,342 staining and annexin v-fitc/pi double staining in sh-sy5y cells. |
2022-01-07 |
2023-08-13 |
Not clear |
| Shu-Ling Hsieh, Jia-Huei Li, Cheng-Di Dong, Chiu-Wen Chen, Chih-Chung W. Carnosine suppresses human colorectal cancer cell proliferation by inducing necroptosis and autophagy and reducing angiogenesis. Oncology letters. vol 23. issue 2. 2022-01-03. PMID:34976156. |
after human colorectal cancer hct-116 cells were treated carnosine for 72 or 96 h, the cell proliferation, apoptosis, autophagy, necroptosis, angiogenesis and the expression of related regulatory molecules were detected using mtt assays, fluorescence image analysis and rt-qpcr in this study. |
2022-01-03 |
2023-08-13 |
human |
| Yulong Wang, Shuiting Zhai, Jianwu Xing, Yingkun He, Tianxiao L. LncRNA GAS5 promotes abdominal aortic aneurysm formation through regulating the miR-185-5p/ADCY7 axis. Anti-cancer drugs. 2022-01-02. PMID:34974476. |
cell viability was detected by mtt assay, and cell apoptosis was assessed by flow cytometry. |
2022-01-02 |
2023-08-13 |
human |
| Jitender K Bhardwaj, Vijay Kumar, Priyanka Saraf, Harish Panchal, Vishavjeet Rathee, Som N Sachdev. Efficacy of N-acetyl- l-cysteine against glyphosate induced oxidative stress and apoptosis in testicular germ cells preventing infertility. Journal of biochemical and molecular toxicology. 2021-12-29. PMID:34964212. |
gly also decreased the cell viability and increased the incidence of apoptosis in testicular cells in a dose- and time-dependent manner as revealed by mtt assay and fluorescence (ethidium bromide/acridine orange) assay, respectively. |
2021-12-29 |
2023-08-13 |
cat |
| Dan Liu, Ye Cheng, Zhipeng Tang, Junliang Chen, Ying Xia, Chengbin Xu, Xiangyu Ca. Potential mechanisms of methylglyoxal-induced human embryonic kidney cells damage: Regulation of oxidative stress, DNA damage, and apoptosis. Chemistry & biodiversity. 2021-12-28. PMID:34962083. |
cell viability, apoptosis and the signaling pathways were measured with mtt, fluorescent staining and western blot experiments, the results showed that mgo could induce oxidative stress and cell inflammation, the level of reactive oxygen species (ros) increased, and p38mapk, jnk and nf-κb signaling pathways were activated. |
2021-12-28 |
2023-08-13 |
human |
| Yang Zhai, Bu-Gu Liu, Xue-Ni Mo, Min Zou, Xiao-Ping Mei, Wei Chen, Guo-Dong Huang, Lin W. Gingerol ameliorates neuronal damage induced by hypoxia-reoxygenation via the miR-210/brain-derived neurotrophic factor axis. The Kaohsiung journal of medical sciences. 2021-12-28. PMID:34962339. |
the levels of viability, apoptosis, and proteins in n2a cells were determined using mtt assays, flow cytometry, and western blotting, respectively. |
2021-12-28 |
2023-08-13 |
Not clear |
| Yen-Po Chen, Po-Chang Shih, Chien-Wei Feng, Chang-Cheng Wu, Kuan-Hao Tsui, You-Hsien Lin, Hsiao-Mei Kuo, Zhi-Hong We. Pardaxin Activates Excessive Mitophagy and Mitochondria-Mediated Apoptosis in Human Ovarian Cancer by Inducing Reactive Oxygen Species. Antioxidants (Basel, Switzerland). vol 10. issue 12. 2021-12-24. PMID:34942985. |
pardaxin induced apoptosis as determined by mtt and tunel assays, as well as activation of caspases-9/3, bid, t-bid, and bax, whereas bcl-2 was downregulated. |
2021-12-24 |
2023-08-13 |
human |
| Jin Zou, Zi-Lin Wan, Lan Yao, Meng-Yao Xu, Shu-Rong Wan. [Rhein inhibits hydrogen peroxide-induced apoptosis of human umbilical vein endothelial cells and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 23. 2021-12-24. PMID:34951247. |
cell survival rate was detected by mtt assay, apoptosis by annexin v-fitc/pi double staining and hoechst 33258 fluorescence staining, autophagy by ad-mcherry-gfp-lc3 b adenovirus transfection, and protein expression by western blot. |
2021-12-24 |
2023-08-13 |
human |
| Xiaofeng Deng, Yongqing Liu, Zesheng Xu, Zichao Wan. lncRNA NRON knockdown alleviates hypoxia/reoxygenation (H/R)-induced cardiomyocyte apoptosis by upregulating HIF-1α expression. Journal of cardiovascular pharmacology. 2021-12-22. PMID:34935702. |
the viability and apoptosis of these cells were evaluated by mtt assay and flow cytometer, respectively. |
2021-12-22 |
2023-08-13 |
mouse |
| Shuang Liu, Wen Yan, Yanbing Hu, Huiying W. Shikonin Alleviates Endothelial Cell Injury Induced by ox-LDL via AMPK/Nrf2/HO-1 Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-12-16. PMID:34912465. |
the mtt method was used to detect cell viability, flow cytometry was used to detect cell apoptosis and reactive oxygen species (ros) levels, and western blot was used to detect protein levels. |
2021-12-16 |
2023-08-13 |
human |
| Fang-Liang Huang, Sheng-Jie Yu, En-Chih Liao, Long-Yuan Li, Pei-Wen Shen, Chia-Ling L. Niclosamide suppresses T‑cell acute lymphoblastic leukemia growth through activation of apoptosis and autophagy. Oncology reports. vol 47. issue 2. 2021-12-16. PMID:34913075. |
following niclosamide treatment, t‑all cell viability was evaluated using mtt assay, and apoptosis with annexin v/propidium iodide staining. |
2021-12-16 |
2023-08-13 |
Not clear |