| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sen Li, Faqing Xie, Kaiwen Shi, Jin Wang, Yan Cao, Yongxiang L. Gossypol ameliorates the IL-1β-induced apoptosis and inflammation in chondrocytes by suppressing the activation of TLR4/MyD88/NF-κB pathway via downregulating CX43. Tissue & cell. vol 73. 2021-11-29. PMID:34534743. |
in treated chondrocytes, according to mtt assay and flow cytometry, gossypol increased viability and reduced apoptosis of il-1β induced chondrocytes. |
2021-11-29 |
2023-08-13 |
Not clear |
| Maryam Mogadasi, Ali Mohammadi, Behnam Emamgolizadeh, Mohammad Reza Alivand, Dara Rahmanpour, Saeed Solal. Investigation the Cytotoxicity of 5-AZA on Acute Lymphoblastic Leukemia Cell Line In Vitro and Characterization the Underlying Molecular Mechanisms of Cell Death and Motility. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue 11. 2021-11-28. PMID:34837933. |
the effect of the 5-aza treatment on cell viability (mtt assay), apoptosis (annexin v/pi staining), microrna (mirna) and mrna expression (real-time pcr) was measured. |
2021-11-28 |
2023-08-13 |
human |
| Xin Zhang, He Nan, Jialong Guo, Jinyu Li. KDM4B Overexpression Promotes the Growth, Migration, and Invasion of Rheumatoid Arthritis Fibroblast-Like Synoviocytes by Activating STAT3 Pathway. Biochemical genetics. vol 59. issue 6. 2021-11-27. PMID:33909202. |
the effects of kdm4b on ra fls viability, apoptosis, migration, and invasion were detected by mtt, flow cytometry, transwell migration, and invasion assays. |
2021-11-27 |
2023-08-13 |
Not clear |
| Zheng Qi, Zhiwei Le, Furui Han, Yajie Feng, Ming Yang, Chenfeng Ji, Liangliang Zha. Inhibitory regulation of purple sweet potato polysaccharide on the hepatotoxicity of tri-(2,3-dibromopropyl) isocyanate. International journal of biological macromolecules. 2021-11-27. PMID:34813788. |
the effect of pspp on the apoptosis of hepg2 cells was detected by mtt assay, the morphological changes were observed by morphological observation, and the apoptosis rate was determined by flow cytometry. |
2021-11-27 |
2023-08-13 |
Not clear |
| Zahra Yazdani, Pooyan Mehrabanjoubani, Alireza Rafiei, Pourya Biparva, Mostafa Karda. Combined Effect of Cold Atmospheric Plasma and Curcumin in Melanoma Cancer. BioMed research international. vol 2021. 2021-11-27. PMID:34825002. |
here, we investigated the combined effects of cap and cur on cytotoxicity and apoptosis in b16-f10 melanoma cancer cells compared to l929 normal cells using mtt method, acridine orange/ethidium bromide fluorescence microscopic assay, and annexin v/pi flow cytometry. |
2021-11-27 |
2023-08-13 |
Not clear |
| Feixiang Chen, Jiadong Zhu, Wei Wan. Ulinastatin Attenuates LPS-Induced Inflammation and Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in Renal Tubular Epithelial Cells via Regulation of the TLR4/NF-κB and Nrf2/HO-1 Pathways. Inflammation. vol 44. issue 6. 2021-11-26. PMID:34585338. |
this study was intended to explore the underlying mechanism by which ulinastatin (uti) influenced the inflammation and apoptosis of renal tubular epithelial cells, hk-2.the effects of uti on the cell viability of hk-2 cells were first measured by mtt and lactate dehydrogenase (ldh) detection kit. |
2021-11-26 |
2023-08-13 |
Not clear |
| Wei-Wei Guo, Ming-Ming Feng, Shuang-Feng Li, Li-Hui We. Circular RNA circ_0023404 serves as a miR-636 sponge to promote malignant behaviors in cervical cancer cells through upregulation of CYP2S1. The Kaohsiung journal of medical sciences. 2021-11-26. PMID:34825467. |
cell proliferation, migration, invasion, and apoptosis were detected by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay, 5-ethynyl-2'-deoxyuridine (edu) assay, colony formation assay, transwell assay, and cytometry assay. |
2021-11-26 |
2023-08-13 |
Not clear |
| Lei Yang, You-Ling Shi, Yan Ma, Wei-Wei Ren, Guang-Ming Pang, Jiao Li. Silencing KLF16 inhibits oral squamous cell carcinoma cell proliferation by arresting the cell cycle and inducing apoptosis. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 2021-11-25. PMID:34779529. |
subsequently, cell proliferation was detected using 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (mtt) assays, cell migration and invasion were detected with wound healing and transwell assays, and cell cycle distribution and cell apoptosis were detected via flow cytometry. |
2021-11-25 |
2023-08-13 |
mouse |
| Junzhe Li, Shijie Xu, Hua Dong, Xiayu Wu, Li-Hong Wang, Xianhua X. Altered Wnt5a expression affects radiosensitivity of non-small cell lung cancer via the Wnt/β-catenin pathway. Experimental and therapeutic medicine. vol 23. issue 1. 2021-11-25. PMID:34815757. |
in the present study, mtt assay and flow cytometric analysis were performed to assess the effect of overexpression or knockdown of wnt5a and/or radiation on the proliferation and apoptosis of nsclc cells. |
2021-11-25 |
2023-08-13 |
Not clear |
| Peijun Sun, Miao Ni. Effect and mechanism of Angelic Shaoyaosan mediated AMPK/SIRT1 positive feedback loop to promote autophagy and regulate the systemic inflammatory response in acute pancreatitis. Cellular and molecular biology (Noisy-le-Grand, France). vol 67. issue 2. 2021-11-25. PMID:34817332. |
in this study, the rat pancreatic acini ar42j cells were chosen as the research object, the application of hyla induced pancreatic acinar cells made model for acute pancreatitis, application of different concentrations of angelica peony spread effect on building cells, thus divided into control group, built in the module, the low concentration group, concentration and high concentration groups, determined by mtt method was applied to explore the above categories in cell proliferation, cell apoptosis was measured by flow cytometry, the expression of inflammatory factors in cell supernatant was determined by enzyme-linked immunoassay, and the expression of autophagy marker proteins lc3- ? |
2021-11-25 |
2023-08-13 |
rat |
| Bing Wen, Chenjiang He, Qin Zhang, Fanglin Zhang, Na Li, Yan Pan, Mengting Deng, Yue Wang, Jianping Li, Jiaxuan Qi. Overexpression of microRNA-221 promotes the differentiation of stem cells from human exfoliated deciduous teeth to neurons through activation of Wnt/β-catenin pathway via inhibition of CHD8. Cell cycle (Georgetown, Tex.). vol 19. issue 23. 2021-11-24. PMID:33198579. |
cell viability, and cell cycle and apoptosis were investigated by mtt assay and flow cytometry respectively. |
2021-11-24 |
2023-08-13 |
human |
| Yinghai Xie, Changwei Liu, Yinci Zhang, Amin Li, Chong Sun, Rui Li, Yingru Xing, Minghong Shi, Qi Wan. PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the PI3K/AKT/mTOR pathways and DNA damage repair. PloS one. vol 16. issue 10. 2021-11-24. PMID:34665844. |
mtt, colony formation, flow cytometry, and immunofluorescence were used to analyze the proliferation, cell cycle, formation of residual γ-h2ax foci, and apoptosis of hcc cells. |
2021-11-24 |
2023-08-13 |
Not clear |
| Shanshan Song, Yang Yang, Jing He, Junfeng Tan. [miR-494 promotes islet β cell proliferation, inhibits apoptosis and increases insulin secretion by activating Wnt/β-catenin signaling pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 37. issue 11. 2021-11-24. PMID:34809740. |
the activity of ins-1 cells was detected by mtt assay; apoptosis was detected by flow cytometry. |
2021-11-24 |
2023-08-13 |
human |
| Xianbo Shen, Yun Chen, Jibin Li, Huaiyin Huang, Chuping Liu, Ning Zho. Identification of Circ_001569 as a Potential Biomarker in the Diagnosis and Prognosis of Pancreatic Cancer. Technology in cancer research & treatment. vol 20. 2021-11-23. PMID:33413045. |
the effects of circ_001569 on the proliferation, migration, invasion, and apoptosis of pc cells were assessed by mtt, wound healing, transwell invasion assays, and flow cytometric analysis, respectively. |
2021-11-23 |
2023-08-13 |
human |
| Gehad Lotfy, Yasmine M Abdel Aziz, Mohamed M Said, El Sayed H El Ashry, El Sayed H El Tamany, Marwa M Abu-Serie, Mohamed Teleb, Alexander Dömling, Assem Baraka. Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators. Bioorganic chemistry. vol 117. 2021-11-23. PMID:34794098. |
the nci-selected derivatives were screened for cytotoxic activities against normal fibroblasts, mda-mb 231, hepg-2, and caco-2 cells via mtt assay, subjected to mechanistic apoptosis studies for assessment of p53, bcl2, p21, and caspase 3/7 status, then evaluated for potential mdm2 inhibition utilizing mst assay. |
2021-11-23 |
2023-08-13 |
Not clear |
| T Kloskowski, K Szeliski, K Krzeszowiak, Z Fekner, Ł Kazimierski, A Jundziłł, T Drewa, M Pokrywczyńsk. Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment. Scientific reports. vol 11. issue 1. 2021-11-23. PMID:34799663. |
cytotoxicity of mumio was analysed in these cell lines via mtt and real-time cell growth assays as well via the assessment of the cytoskeleton, apoptosis, and cell cycle. |
2021-11-23 |
2023-08-13 |
Not clear |
| Sahar Sadegh-Nejadi, Reza Afrisham, Solaleh Emamgholipour, Pantea Izadi, Neda Eivazi, Behnoosh Tahbazlahafi, Maliheh Pakneja. Influence of plasma circulating exosomes obtained from obese women on tumorigenesis and tamoxifen resistance in MCF-7 cells. IUBMB life. vol 72. issue 9. 2021-11-22. PMID:32542981. |
for evaluating resistance to tamoxifen, the cell viability, apoptosis, and the p53 protein were evaluated using the mtt assay, flow cytometry, and western blot methods, respectively. |
2021-11-22 |
2023-08-13 |
Not clear |
| Seyed Ali Nabipoorashrafi, Navid Shomali, Leila Sadat-Hatamnezhad, Mahmoud Mahami-Oskouei, Javad Mahmoudi, Babak Sandoghchian Shotorbani, Morteza Akbari, Huaxi Xu, Siamak Sandoghchian Shotorban. miR-143 acts as an inhibitor of migration and proliferation as well as an inducer of apoptosis in melanoma cancer cells in vitro. IUBMB life. vol 72. issue 9. 2021-11-22. PMID:32687246. |
also, the role of mir-143 in the induction of apoptosis and inhibition of proliferation by flow cytometry and mtt was confirmed. |
2021-11-22 |
2023-08-13 |
human |
| Xin Wang, Youlu Lu, Zhouting Tuo, Huan Zhou, Ying Zhang, Zhangjun Cao, Longfei Peng, Dexin Yu, Liangkuan B. Role of SIRT1/AMPK signaling in the proliferation, migration and invasion of renal cell carcinoma cells. Oncology reports. vol 45. issue 6. 2021-11-22. PMID:33907836. |
transwell, mtt and flow cytometry apoptosis assays were performed to evaluate the migration, invasion, proliferation and early apoptosis level of rcc cells. |
2021-11-22 |
2023-08-13 |
human |
| Lili Du, Jiexian Jing, Yan Wang, Xiaoqin Xu, Ting Sun, Yanchun Shi, Weigang Wang, Baoguo Tian, Cunzhi Han, Xianwen Zhao, Huibo Chan. Knockdown of SASS6 reduces growth of MDA‑MB‑231 triple‑negative breast cancer cells through arrest of the cell cycle at the G2/M phase. Oncology reports. vol 45. issue 6. 2021-11-22. PMID:33907854. |
cell viability was determined using an mtt assay, and cell cycle distribution and apoptosis were measured using flow cytometry. |
2021-11-22 |
2023-08-13 |
Not clear |