| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sathya Rathish Mohana Jeevanath, Manjari Venkatraman, Kalaivanan Karuppan, Abarna Balasubramani, Natarajan Mohan, Siva Annamala. Bioinformation. vol 20. issue 11. 2025-03-31. PMID:40162453. |
hela cell lines were used to assess the antiproliferative activity tu using the mtt assay and apoptosis by annexin v flow cytometry. |
2025-03-31 |
2025-04-03 |
human |
| Farha A Ali Shafi, Ali Thoulfikar A Imeer, Hassan Ali Abood Nassrullah, Ali Mutashar Naeema. The impact of extracellular glucose concentrations on antioxidant capacity, viability, and microRNA expression in TM4 Sertoli cells. Reproductive biology. vol 25. issue 2. 2025-03-31. PMID:40163939. |
cell viability and apoptosis were evaluated using mtt assay and acridine-orange staining. |
2025-03-31 |
2025-04-03 |
Not clear |
| Sara Mohiti, Effat Alizadeh, Line S Bisgaard, Mehrangiz Ebrahimi-Mameghani, Christina Christofferse. The AhR/P38 MAPK pathway mediates kynurenine-induced cardiomyocyte damage: The dual role of resveratrol in apoptosis and autophagy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 186. 2025-03-28. PMID:40153993. |
cell viability, apoptosis, mitochondrial membrane potential, and autophagy were assessed using mtt, tunel, jc-1, and autophagy detection assays. |
2025-03-28 |
2025-04-01 |
Not clear |
| Faranak Karamifard, Ali Dadbinpour, Mahta Mazaher. An in- vitro measurement for the toxicity of peptides inhibit hexokinase II in breast cancer cell lines. Scientific reports. vol 15. issue 1. 2025-03-28. PMID:40148397. |
this study examined the toxic effect of peptides that inhibit enzyme interaction on tumorigenic mcf-7 and mda-mb-231 and non-tumorigenic mcf10a cell lines through mtt analysis and flow cytometry to determine cell apoptosis. |
2025-03-28 |
2025-03-30 |
Not clear |
| Mahdiyeh Bakhtiyari-Ramezani, Meysam Nasiri, Mansoureh Baniasad. Helium and argon cold plasma effects on the 4T1 cancer cells and a triple negative mouse model of breast cancer. Scientific reports. vol 15. issue 1. 2025-03-28. PMID:40148523. |
in vitro evaluations on 4t1 cell line using the mtt assays and flow cytometry analysis demonstrate cap-induced apoptosis in all treated groups, especially in the direct approach. |
2025-03-28 |
2025-03-30 |
mouse |
| Sara Cheleschi, Nicola Mondanelli, Iole Seccafico, Roberta Corsaro, Elena Moretti, Giulia Collodel, Antonella Fioravant. Role of lncRNA XIST/miR-146a Axis in Matrix Degradation and Apoptosis of Osteoarthritic Chondrocytes Through Regulation of MMP-13 and BCL2. Biology. vol 14. issue 3. 2025-03-26. PMID:40136478. |
viability was detected using mtt; apoptosis using cytometry; and xist, mir-146a, b-cell lymphoma (bcl)2, and metalloproteinase (mmp)-13 expression using real-time pcr. |
2025-03-26 |
2025-03-28 |
human |
| JinLian Li, JianZheng Yang, ShiFeng Lai, QingLan He, ShiYing Li, LinLing Liu, MingXing L. Evaluation of melittin-induced acute kidney injury in different degrees in rats by Contrast-enhanced ultrasound techniques. SLAS technology. 2025-03-23. PMID:40122384. |
the correlations among the quantitative parameters of ceus tic, cr and apoptosis marker of pcr were analyzed.results shows: 1.the quantitative parameters of ceus tic(peak, tp, auc, mtt) and apoptosis markers pcr parameters (bax, bcl-2, casepase3) were significantly different among three groups (p < 0.01);2. |
2025-03-23 |
2025-03-26 |
rat |
| Zhaorong Yue, Fei Xie, Ruyue Wang, Xin Wang, Hongyu L. Lienal Polypeptide Decreases Immune Thrombocytopenia in a Mouse Model by Upregulating Cytokine Production and Increasing the Levels of CD4 Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2025-03-20. PMID:40113259. |
we first assessed the effects of lp on meg-01 megakaryocytic cells regarding proliferation, apoptosis, and differentiation using methylthiazolyldiphenyl-tetrazolium bromide (mtt) assays, western blot analysis, and flow cytometry for apoptosis and cd41 expression as a differentiation marker. |
2025-03-20 |
2025-03-23 |
mouse |
| Qing Tan, Dongyun Gao, Xu H. FOXD1-activated ANXA3 facilitates cisplatin resistance of lung cancer cells via promoting ANXA4 expression. Naunyn-Schmiedeberg's archives of pharmacology. 2025-03-17. PMID:40095055. |
the ddp resistance, viability, apoptosis, invasion, and migration were determined by cck8 assay, mtt assay, flow cytometry, tunel staining, transwell assay, and wound healing assay. |
2025-03-17 |
2025-03-20 |
Not clear |
| Shubham Upadhayay, Vivek Uttam, Puneet Kuma. G-Protein-Coupled Estrogen Receptor 1 (GPER1) Activation Mitigates Haloperidol-Induced Neurotoxicity in SHSY-5Y Cells and Improves Motor Functions in Adult Zebrafish. Neurochemical research. vol 50. issue 2. 2025-03-15. PMID:40087195. |
moreover, cell viability was analyzed using mtt assay; apoptosis was done using a confocal microscope, and molecular mechanism investigated through western blot and qrt-pcr analysis. |
2025-03-15 |
2025-03-18 |
zebrafish |
| Chenghui Lu, Dehao Yu, Xufu Wang, Jiao Li, Yingying Zhang, Congcong Wang, Qiang Jia, Jian Tan, Wei Zheng, Huabing Sun, Zhaowei Men. Selective Therapeutic Potential of a H2O2-Inducible DNA Interstrand Cross-linker in Anaplastic Thyroid Carcinoma. Endocrinology. vol 166. issue 4. 2025-03-14. PMID:39950985. |
in vitro analysis included fluorescence microscopy for h2o2 levels and exposure of atc cells to various hp-icl concentrations followed by assessment of cell viability, apoptosis, cell cycle, and dna damage using methyl thiazolyl tetrazolium (mtt), flow cytometry, and a γh2ax assay. |
2025-03-14 |
2025-03-16 |
mouse |
| Masoud Pourrahim, Leila Zolghad. Clay-based magnetite nano carriers for breast cancer treatment: Apoptosis induction and physicochemical properties. Heliyon. vol 11. issue 4. 2025-03-14. PMID:40083996. |
also, flow cytometry and mtt were used to investigate the induction of apoptosis and toxicity, respectively. |
2025-03-14 |
2025-03-16 |
Not clear |
| Gaotao Zhang, Zhiqin Liu, Yuanzhuang Xu, Fei Cao, Xiaowei Huo, Queting Chen, Duqiang Lu. Exploring the mechanism of baicalein on breast cancer based on network pharmacology, molecular docking and in vivo experiments. Toxicology and applied pharmacology. 2025-03-13. PMID:40081541. |
the effects of baicalein on cellular proliferation, the cell cycle, and apoptosis were assessed through mtt assays, plate cloning, and flow cytometry techniques. |
2025-03-13 |
2025-03-16 |
mouse |
| Ashwini S Sanji, J Manasa, John F Kennedy, S Veeresh, A S Kamalanathan, Maruti J Gurav, Prasanna H Megalamani, Ram Kaulgud, Vishwanath B Chachad. Purification and characterization of lectin from Phyllanthus reticulatus (PRL) plant fruit inducing cytotoxic effect on T47D and SKBR3 breast cancer cell lines. International journal of biological macromolecules. 2025-03-13. PMID:40081710. |
notably, prl exhibited a dose-dependent cytotoxic effect on t47d and skbr3 breast cancer cell lines by inducing apoptosis, as assessed through mtt assay and annexin v/pi staining. |
2025-03-13 |
2025-03-16 |
Not clear |
| Yuepeng An, Qing Zhang, Jiusi Zhao, Nan Zhen. Tangeretin regulates oxidative stress in cutaneous melanoma cells via the Nrf2 signaling pathway. Archives of dermatological research. vol 317. issue 1. 2025-03-12. PMID:40072600. |
the effects of tangeretin on cell proliferation, migration, invasion, and apoptosis were assessed using mtt, wound healing, transwell invasion, and flow cytometry assays, respectively. |
2025-03-12 |
2025-03-15 |
human |
| Zahra Zare-Badie, Farahnaz Zare, Banafsheh Rastegari, Gholamhossein Tamaddo. Combination therapy using parthenolide and doxorubicin induces apoptosis in Raji cells: insights into miR-27b and signaling pathway alterations. Medical oncology (Northwood, London, England). vol 42. issue 4. 2025-03-12. PMID:40072647. |
raji cells were treated with varying concentrations of parthenolide and doxorubicin for 48 and 72 h, cell viability was assessed using the mtt assay, and apoptosis was quantified using flow cytometry. |
2025-03-12 |
2025-03-15 |
Not clear |
| Muhammed Güngören, Muhammed Gungoren, Ismail Koyuncu, Ersin Kilinc, Zubeyde Baysa. Docetaxel-loaded, dipeptide-functionalized γ-Fe2O3 magnetic nanoparticles: Synthesis, characterization and targeting to prostate cancer. Chemistry & biodiversity. 2025-03-12. PMID:40071627. |
after docetaxel was bound to the synthesized carrier, its therapeutic effect was measured by spectrophotometric and flowcytometric methods (mtt, ros and apoptosis). |
2025-03-12 |
2025-03-14 |
Not clear |
| Mehrdad Aghasizadeh, Tayebe Moghaddam, Ahmad Reza Bahrami, Hamid Sadeghian, Seyed Jamal Alavi, Tahmineh Kazemi, Maryam M Mati. Evaluation of several farnesyloxycarbostyril derivatives as potential 15-LOX-1 inhibitors for prostate cancer treatment. Toxicology and applied pharmacology. 2025-03-08. PMID:40057000. |
the mtt assay revealed a dose- and time-dependent toxicity of the compounds on pca cells, and flow cytometry results indicated that apoptosis served as the dominant mechanism of cell death. |
2025-03-08 |
2025-03-12 |
mouse |
| Abbas Ranjbar, Saeid Taghiloo, Parvin Nozari, Akbar Hedayatizadeh-Omran, Hossein Asgarian-Omra. Effects of c-Kit Receptor, AKT, and NF-κB Inhibitors on Immune Evasion in Multiple Myeloma Cells. Iranian journal of allergy, asthma, and immunology. vol 24. issue 1. 2025-03-07. PMID:40052893. |
apoptosis and cell viability were evaluated using flow cytometry and mtt assays, respectively. |
2025-03-07 |
2025-03-09 |
Not clear |
| Sania Ghobadi Alamdari, Reza Mohammadzadeh, Mohammad Amini, Souzan Najafi, Behzad Baradaran, Seyedeh Zahra Bahojb Mahdavi, Amirhossein Yari, Amir Ali Mokhtarzade. Improvement of carboplatin chemosensitivity in lung cancer cells by siRNA-mediated downregulation of DLGAP1-AS2 expression. Scientific reports. vol 15. issue 1. 2025-03-07. PMID:40055367. |
the viability of the cells was assessed using the mtt assay, and apoptosis induction was examined through annexin v/pi staining. |
2025-03-07 |
2025-03-12 |
human |