| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Fan, Xinying Li, Wei Jiang, Yun Huang, Jingdong Li, Zhiming Wan. A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells. Experimental and therapeutic medicine. vol 5. issue 4. 2021-10-21. PMID:23599737. |
cell growth, cell cycle transition and apoptosis were measured by mtt assay and flow cytometry. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yali Song, Gong Zhang, Xiulan Zhu, Zhanjun Pang, Fuqi Xing, Song Qua. Overexpression of the hydatidiform mole-related gene F10 inhibits apoptosis in A549 cells through downregulation of BCL2-associated X protein and caspase-3. Oncology letters. vol 4. issue 3. 2021-10-21. PMID:23741243. |
untransfected a549, a549-f10 or a549-empty cells were examined using the mtt cell proliferation assay and the tunel-fitc/hoechst 33258 apoptosis assay. |
2021-10-21 |
2023-08-12 |
human |
| Yong Chen, Ying Gao, Ye Tian, DA-Li Tia. PRKACB is downregulated in non-small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP-A2 cells. Oncology letters. vol 5. issue 6. 2021-10-21. PMID:23833645. |
a plasmid containing full-length prkacb was transfected into ltep-a2 cells to further investigate the effects of prkacb overexpression on proliferation, apoptosis and invasion of the transfected cells, which were examined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), colony formation, flow cytometry and transwell assays. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yubin Mao, Jinfei Xu, Gang Song, Nini Zhang, Hao Yi. Twist2 promotes ovarian cancer cell survival through activation of Akt. Oncology letters. vol 6. issue 1. 2021-10-21. PMID:23946798. |
dfo-induced apoptosis was examined by fluorescence microscopy, mtt assays and flow cytometry. |
2021-10-21 |
2023-08-12 |
human |
| Chuantao Suo, Libo Sun, Shuang Yan. Alpinetin activates the δ receptor instead of the κ and μ receptor pathways to protect against rat myocardial cell apoptosis. Experimental and therapeutic medicine. vol 7. issue 1. 2021-10-21. PMID:24348774. |
the mtt method was used to evaluate cell viability and annexin v-fluorescein isothiocyanate (fitc)/propidium iodide (pi) staining was used to analyze apoptosis. |
2021-10-21 |
2023-08-12 |
rat |
| Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Ta. JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen-activated protein kinase signaling pathways. Experimental and therapeutic medicine. vol 7. issue 6. 2021-10-21. PMID:24926382. |
western blot analysis was conducted to observe the effect of jwa on apoptosis and the regulatory effect of jwa on proliferation was determined using a thiazolyl blue tetrazolium bromide (mtt) assay. |
2021-10-21 |
2023-08-13 |
human |
| Chen-Feng Ji, Yu-Bin J. Apoptosis of human gastric cancer SGC-7901 cells induced by podophyllotoxin. Experimental and therapeutic medicine. vol 7. issue 5. 2021-10-21. PMID:24940431. |
mtt assays and flow cytometry were used to evaluate the effects of podophyllotoxin on the proliferation and apoptosis of sgc-7901 cells, while fluorescence inverted microscopy was used to observe the morphology of sgc-7901 cells that had been dyed with hoechst 33258. |
2021-10-21 |
2023-08-13 |
human |
| Ling Liu, Feng Ding, Jiwei Chen, Boyong Wang, Zhisu Li. hSulf-1 inhibits cell proliferation and migration and promotes apoptosis by suppressing stat3 signaling in hepatocellular carcinoma. Oncology letters. vol 7. issue 4. 2021-10-21. PMID:24944651. |
mtt and transwell chamber assays, as well as annexin v/propidium iodide double-staining methods, were used to examine the effects of hsulf-1 on stat3-mediated motility, proliferation and apoptosis in hepg2 cells. |
2021-10-21 |
2023-08-13 |
human |
| Qingsong Liu, Xiong Yan Luo, Hong Jiang, Ming-Hui Yang, Guo-Hua Yuan, Zhong Tang, He Wan. Hydroxychloroquine facilitates autophagosome formation but not degradation to suppress the proliferation of cervical cancer SiHa cells. Oncology letters. vol 7. issue 4. 2021-10-21. PMID:24944668. |
mtt and flow cytometry were adopted respectively to assess the proliferation and apoptosis of the siha cells. |
2021-10-21 |
2023-08-13 |
Not clear |
| Qingsong Liu, Xiong Yan Luo, Hong Jiang, Ming-Hui Yang, Guo-Hua Yuan, Zhong Tang, He Wan. Hydroxychloroquine facilitates autophagosome formation but not degradation to suppress the proliferation of cervical cancer SiHa cells. Oncology letters. vol 7. issue 4. 2021-10-21. PMID:24944668. |
however, hcq may promote siha cell apoptosis as the mtt, apoptotic assay and mirna-9* results revealed. |
2021-10-21 |
2023-08-13 |
Not clear |
| Xingmei Zhang, Huiyu Liang, Yan Tan, Xidong Wu, Shuji Li, Yusheng Sh. A U87-EGFRvIII cell-specific aptamer mediates small interfering RNA delivery. Biomedical reports. vol 2. issue 4. 2021-10-21. PMID:24944794. |
western blotting was performed to detect changes in the c-met protein expression, and mtt and annexin v-fluorescein isothiocyanate/propidium iodine assays were used to determine changes in the proliferation and apoptosis of u87-egfrviii cells, respectively. |
2021-10-21 |
2023-08-13 |
Not clear |
| Xiang Huang, Jianhua Zhou, Junyan Liu, Binzhi Tang, Fengyan Zhao, Yi Q. Biological characteristics of prostate cancer cells are regulated by hypoxia-inducible factor 1α Oncology letters. vol 8. issue 3. 2021-10-21. PMID:25120692. |
cell proliferation, apoptosis and migration were assessed using mtt, terminal deoxynucleotidyl transferase-mediated dutp nick end labeling and boyden chamber assays. |
2021-10-21 |
2023-08-13 |
Not clear |
| Bo Yi, Xiaorong Hu, Zhongyuan Wen, Ting Zhang, Yuli Ca. Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits hyperglycemia-induced apoptosis in myocytes by suppressing receptor for advanced glycation end products expression. Experimental and therapeutic medicine. vol 8. issue 4. 2021-10-21. PMID:25187821. |
cell apoptosis was detected using an annexin v-fluorescein isothiocyanate/propidium iodide kit, and cell viability was measured using an mtt assay. |
2021-10-21 |
2023-08-13 |
rat |
| Peifen Fu, Feiya DU, Minya Yao, Kezhen Lv, Yu Li. MicroRNA-185 inhibits proliferation by targeting c-Met in human breast cancer cells. Experimental and therapeutic medicine. vol 8. issue 6. 2021-10-21. PMID:25371748. |
in addition, an mtt assay and flow cytometry were used to determine the rates of cell proliferation and apoptosis. |
2021-10-21 |
2023-08-13 |
human |
| Hui Chen, Yuan Guo, Xingbo Chen. Long non-cording RNA XIST promoted cell proliferation and suppressed apoptosis by miR-423-5p/HMGA2 axis in diabetic nephropathy. Molecular and cellular biochemistry. vol 476. issue 12. 2021-10-21. PMID:34532814. |
the impacts of xist depletion on viability and apoptosis were assessed by 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt) and flow cytometry assays in hg-induced hk cells. |
2021-10-21 |
2023-08-13 |
human |
| Xiaojing Deng, Hailun Zheng, Dapeng Li, Yongju Xue, Qizhi Wang, Shanjun Yan, Yu Zhu, Min Den. MicroRNA-34a regulates proliferation and apoptosis of gastric cancer cells by targeting silent information regulator 1. Experimental and therapeutic medicine. vol 15. issue 4. 2021-10-20. PMID:29581731. |
the mtt method and flow cytometry was used to measure cell proliferation and apoptosis. |
2021-10-20 |
2023-08-13 |
human |
| Kun-Sheng Li, Yang Bai, Jie Li, Shi-Liang Li, Jun Pan, Yong-Qing Cheng, Kai Li, Zhi-Gang Wang, Wen-Jie Ji, Qing Zhou, Dong-Jin Wan. LncRNA HCP5 in hBMSC-derived exosomes alleviates myocardial ischemia reperfusion injury by sponging miR-497 to activate IGF1/PI3K/AKT pathway. International journal of cardiology. vol 342. 2021-10-20. PMID:34311013. |
mtt assay and flow cytometry were used to measure cell viability and apoptosis, respectively. |
2021-10-20 |
2023-08-13 |
rat |
| Jing Qian, Mo Yang, Qiang Feng, Xin-Yan Pan, Li-Lin Yang, Ju-Lun Yan. Inhibition of glioma by adenovirus KGHV500 encoding anti-p21Ras scFv and carried by cytokine-induced killer cells. Experimental biology and medicine (Maywood, N.J.). vol 246. issue 10. 2021-10-19. PMID:33535808. |
in this study, the human glioma cell line u251 was co-cultured with recombinant adenovirus kghv500, and the anti-tumor effects of kghv500 were determined by mtt, scratch test, transwell invasion, and apoptosis assays. |
2021-10-19 |
2023-08-13 |
human |
| HuiMin Li, Yan Wang, Bin Wang, Min Li, JiPing Liu, HongLian Yang, YongHeng Sh. Baicalin and Geniposide Inhibit Polarization and Inflammatory Injury of OGD/R-Treated Microglia by Suppressing the 5-LOX/LTB4 Pathway. Neurochemical research. vol 46. issue 7. 2021-10-18. PMID:33891262. |
the effects of different concentrations of bc, gp, and bc/gp (6.25 μm, 12.5 μm, and 25 μm) on cell viability and apoptosis of microglia were evaluated by mtt and flow cytometry. |
2021-10-18 |
2023-08-13 |
Not clear |
| Lianggeng Xiong, Binxin Tan, Xiubing Lei, Biao Zhang, Wenting Li, Daimei Liu, Tian Xi. SIRT6 through PI3K/Akt/mTOR signaling pathway to enhance radiosensitivity of non-Small cell lung cancer and inhibit tumor progression. IUBMB life. vol 73. issue 9. 2021-10-15. PMID:34033225. |
then, check the cell proliferation, migration, apoptosis and cell cycle by mtt, wound healing assay and flow cytometry, while detect the expression of pi3k/akt/mtor signaling pathway-related proteins by western blot. |
2021-10-15 |
2023-08-13 |
mouse |