| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin Li, Yimeng Lei, Ziyu Gao, Gang Wu, Wei Gao, Liping Xia, Jing Lu, Hui She. IL-34 affects fibroblast-like synoviocyte proliferation, apoptosis and function by regulating IL-17. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:34385542. |
in this study, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry of annexin v and pi staining were performed to assess cell proliferation and apoptosis progression in ra-flss after stimulated with increasing concentrations of il-34, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Tongyin Zhang, Daofei Ji, Junyi Sun, Jiangling Song, Limin Nie, Na Su. NPAS4 suppresses propofol-induced neurotoxicity by inhibiting autophagy in hippocampal neuronal cells. Archives of biochemistry and biophysics. vol 711. 2021-11-12. PMID:34418347. |
cell viability, lactate dehydrogenase (ldh) release, caspase-3 activity, and apoptosis were evaluated by mtt, a ldh-cytotoxicity assay kit, a caspase-3 colorimetric assay kit, and tunel assay, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Kun Ma, Chuan Zhang, Wuyin L. Fascin1 mediated release of pro-inflammatory cytokines and invasion/migration in rheumatoid arthritis via the STAT3 pathway. Cell cycle (Georgetown, Tex.). vol 20. issue 21. 2021-11-12. PMID:34499588. |
functional analysis contained mtt assay, flow cytometry,transwell™ assays, wound healing, quantitative polymerase chain reaction and western blotting were used to detect cell proliferation,apoptosis ratio, invasion/ migration, the mrna and protein expression of the realted markers, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Xiaohui Xu, Yong Wu, Ke Yi, Yan Hu, Weiqun Ding, Chungen Xin. IRF1 regulates the progression of colorectal cancer via interferon‑induced proteins. International journal of molecular medicine. vol 47. issue 6. 2021-11-11. PMID:33907823. |
mtt, 5‑ethynyl‑20‑deoxyuridine, colony formation, cell cycle alteration and apoptosis assays were performed in crc cell lines. |
2021-11-11 |
2023-08-13 |
mouse |
| Xinyan Ma, Ying Zhang, Mingyang Guan, Weidong Zhang, Huifang Tian, Caixiao Jiang, Xiaoxin Tan, Weijun Kan. Genotoxicity of chloroacetamide herbicides and their metabolites International journal of molecular medicine. vol 47. issue 6. 2021-11-11. PMID:33907828. |
the effects of ac, cmepa and mea on dna breakage, mapk/erk pathway activity, viability and apoptosis of hepg2 cells were examined by comet assay, western blotting, mtt assay and flow cytometry, respectively. |
2021-11-11 |
2023-08-13 |
zebrafish |
| Grzegorz Adamczuk, Ewelina Humeniuk, Magdalena Iwan, Dorota Natorska-Chomicka, Kamila Adamczuk, Agnieszka Korga-Plewk. The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line. Molecules (Basel, Switzerland). vol 26. issue 18. 2021-11-11. PMID:34577124. |
the cytotoxic effect of teriflunomide-an active metabolite of leflunomide-was determined using mtt assay, apoptosis detection, and cell cycle analysis. |
2021-11-11 |
2023-08-13 |
Not clear |
| Xiangyu Cao, Chengying Liu, Mengmeng Zhang, Ruochen Bi, Mingyang Fu, Elena Korik, Jiahe Chen, Jianyun Gao, Igor Semak, Jianli Li. Bovine lactoferrin and Lentinus edodes mycelia polysaccharide complex: The formation and the activity to protect islet β cells. International journal of biological macromolecules. vol 191. 2021-11-11. PMID:34592222. |
cell viability, reactive oxygen species (ros) level, apoptosis and the related signaling pathways were detected with thiazolyl blue tetrazolium bromide (mtt) assay, 2,7-dichlorofluorescin diacetate (dcfh-da) staining, hoechst 33258 staining and western blot methods respectively. |
2021-11-11 |
2023-08-13 |
cattle |
| Yu Zhou, Xiaohong Li, Yaju Duan, Yong Luo, Shuling Tang, Jian Wan. LncRNA MALAT-1 regulates the growth of interleukin-22-stimulated keratinocytes via the miR-330-5p/S100A7 axis. Autoimmunity. 2021-11-11. PMID:34761722. |
cell proliferation, inflammation, and apoptosis were detected by the mtt assay, western blotting, and flow cytometry analysis, respectively. |
2021-11-11 |
2023-08-13 |
Not clear |
| Rakshanaa R, Mohiraa Shafreen, Nitin Kuma. Inhibition of Proliferation in Ovarian Cancer Cell Line (PA-1) by the Action of Green Compound "Betanin". Applied biochemistry and biotechnology. 2021-11-11. PMID:34762269. |
determination of ic50 values through mtt assay was carried out, in addition measurement of mitochondrial membrane potential (mmp), effect of reactive oxygen species (ros) generation, and induction of apoptosis in ovarian cancer cells through betanin was also observed. |
2021-11-11 |
2023-08-13 |
Not clear |
| Dan Zou, Jin Bai, Enting Lu, Chunjiao Yang, Jiaqing Liu, Zhenpeng Wen, Xuqin Liu, Zi Jin, Mengdan Xu, Lei Jiang, Ye Zhang, Yi Zhan. Identification of Novel Drug Candidate for Epithelial Ovarian Cancer Frontiers in oncology. vol 11. 2021-11-10. PMID:34745968. |
the cytotoxicity of drug candidates was assessed by mtt and colony formation analysis, the proteins coded by hub genes were detected by western blots, and apoptosis analysis was evaluated by flow cytometry. |
2021-11-10 |
2023-08-13 |
Not clear |
| Hua-Xia Xie, Zhi-Yuan Xu, Jia-Ning Tang, Yi-An DU, Ling Huang, Peng-Fei Yu, Xiang-Dong Chen. Effect of Huaier on the proliferation and apoptosis of human gastric cancer cells through modulation of the PI3K/AKT signaling pathway. Experimental and therapeutic medicine. vol 10. issue 3. 2021-11-09. PMID:26622467. |
the mtt assay was used to measure the effects of huaier on the growth of the cells, while cell cycle distribution and apoptosis levels were analyzed using flow cytometry. |
2021-11-09 |
2023-08-13 |
human |
| Xiaolin Lin, Ting Han, Qing Xia, Jiujie Cui, Meng Zhuo, Yiyi Liang, Wenyu Su, Lisha Wang, Liwei Wang, Zebing Liu, Xiuying Xia. CHPF promotes gastric cancer tumorigenesis through the activation of E2F1. Cell death & disease. vol 12. issue 10. 2021-11-09. PMID:34564711. |
cultured gastric cancer cells and human gastric epithelial cell line ges1 were used to investigate the effects of shchpf and she2f1 on the development and progression of gastric cancer by mtt, western blotting, flow cytometry analysis of cell apoptosis, colony formation, transwell and gastric cancer xenograft mouse models, in vitro and in vivo. |
2021-11-09 |
2023-08-13 |
mouse |
| Xiaoping Pan, Xiaolv Hong, Sumei Li, Ping Meng, Feng Xia. METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner. Experimental & molecular medicine. vol 53. issue 1. 2021-11-08. PMID:33420414. |
cultured adr-resistant mcf-7 cells were assayed for their half maximal inhibitory concentration (ic50) values and apoptosis using an mtt assay and annexin v-fitc/pi-labeled flow cytometry, and the cells were then xenografted into nude mice. |
2021-11-08 |
2023-08-13 |
mouse |
| Yujie Zhang, Ailing Zhen. MiR-142-5p promotes retinoblastoma cell proliferation, migration and invasion by targeting PTEN. Journal of biochemistry. vol 170. issue 2. 2021-11-08. PMID:34562091. |
the proliferation, migration, invasion and cell apoptosis were measured using mtt assay, brdu assay, transwell experiments and flow cytometry analysis, respectively. |
2021-11-08 |
2023-08-13 |
Not clear |
| Yu Jin Jung, Hyunsu Choi, Eungseok O. Effects of particulate matter and nicotine for the MPP+-induced SH-SY5Y cells: Implication for Parkinson's disease. Neuroscience letters. vol 765. 2021-11-08. PMID:34563623. |
cell viability and apoptosis were measured using mtt and tunel assays, respectively. |
2021-11-08 |
2023-08-13 |
Not clear |
| Hao Wang, Zhinan Liu, Zhuo Sun, Dong Zhou, Hanyan Mao, Guohua Den. Ubiquitin specific peptidase 33 promotes cell proliferation and reduces apoptosis through regulation of the SP1/PI3K/AKT pathway in retinoblastoma. Cell cycle (Georgetown, Tex.). vol 20. issue 19. 2021-11-05. PMID:34470581. |
usp33 effects on cell growth, cycle, apoptosis and tumorigenesis were studied using mtt, edu, cycle and western blotting and |
2021-11-05 |
2023-08-13 |
Not clear |
| Guangwen Zhang, Baojian Liu, Zhaoyang Zeng, Qinghai Chen, Yiyun Feng, Xueqian Nin. Oxymatrine hydrazone (OMTH) synthesis and its protective effect for rheumatoid arthritis through downregulation of MEK/NF-κB pathway. Environmental toxicology. vol 36. issue 12. 2021-11-04. PMID:34459104. |
cell viability and apoptosis were detected using mtt and flow cytometry assays, respectively. |
2021-11-04 |
2023-08-13 |
Not clear |
| Jun Zhou, Wanpin Nie, Jiajia Yuan, Zeyu Zhang, Liangliang Mi, Changfa Wang, Ranglang Huan. GSG2 knockdown suppresses cholangiocarcinoma progression by regulating cell proliferation, apoptosis and migration. Oncology reports. vol 45. issue 6. 2021-11-03. PMID:33846801. |
subsequently, cell proliferation, apoptosis, cell cycle distribution and migration were measured by mtt, flow cytometry, and wound healing assays, respectively |
2021-11-03 |
2023-08-13 |
Not clear |
| Dongwei Zhang, Yongfu Zhu, Ya Su, Minghui Yu, Xiaozhou Xu, Chunhua Wang, Shaohu Zhang, Liming Xi. Taurochenodeoxycholic acid inhibits the proliferation and invasion of gastric cancer and induces its apoptosis. Journal of food biochemistry. 2021-11-03. PMID:34278593. |
cell proliferation, apoptosis, and invasion were subjected to 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (mtt) assay, flow cytometry, and transwell assay. |
2021-11-03 |
2023-08-13 |
mouse |
| Yuyan Guo, Tao Gao, Fang Fang, Shuang Sun, Dayu Yang, Yongji Li, Shaowa L. A novel polymer micelle as a targeted drug delivery system for 10-hydroxycamptothecin with high drug-loading properties and anti-tumor efficacy. Biophysical chemistry. vol 279. 2021-11-03. PMID:34547633. |
cellular uptake, cytotoxicity, and apoptosis were assessed using flow cytometry and mtt assays. |
2021-11-03 |
2023-08-13 |
Not clear |