| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dong Liang, Zehui Fang, Min Dong, Chao Liang, Chonghao Xing, Juan Zhao, Yiju Yan. Effect of RNA interference-related HiWi gene expression on the proliferation and apoptosis of lung cancer stem cells. Oncology letters. vol 4. issue 1. 2021-10-21. PMID:22807978. |
the conditions of lung cancer tsc proliferation and apoptosis in each group were examined using an mtt assay, fluorescence-activated cell sorting and annexin v staining. |
2021-10-21 |
2023-08-12 |
Not clear |
| Jun Chang, Wei Wang, Hui Zhang, Yong Hu, Zongsheng Yi. Bisphosphonates regulate cell proliferation, apoptosis and pro-osteoclastic expression in MG-63 human osteosarcoma cells. Oncology letters. vol 4. issue 2. 2021-10-21. PMID:22844373. |
the mtt assay showed that zol induced a distinct dose- and time-dependent reduction of cell viability with an ic(50) value of 52.37±1.0 μm for 72 h. flow cytometric analysis further revealed that the cell apoptosis was induced by arrest of the cell cycle in the g(1) phase. |
2021-10-21 |
2023-08-12 |
human |
| Chuan-Jiang Yu, Su-Juan Ye, Zhi-Hua Feng, Wen-Jing Ou, Xi-Kun Zhou, Ling-Dong Li, Yong-Qiu Mao, Wen Zhu, Yu-Quan We. Effect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells. Oncology letters. vol 1. issue 4. 2021-10-21. PMID:22966375. |
mtt assay and flow cytometry showed that fraxiparine slightly inhibited the cell viability dose- and time-dependently, but did not arrest the a549 cells in the g1 phase nor induce early apoptosis. |
2021-10-21 |
2023-08-12 |
human |
| Ying Chen, Yong Cao, Danlei Yang, Kaiyan Li, Zhengyun Wang, Jing Zhu, Hansvin Bunjhoo, Shengdao Xiong, Yongjian Xu, Weining Xion. Increase of the therapeutic effect on non-small-cell lung cancer cells with combination treatment of shRNA against Cyclin D1 and Bcl-xL in vitro. Experimental and therapeutic medicine. vol 3. issue 2. 2021-10-21. PMID:22969878. |
the apoptosis and proliferation of the two cell lines were evaluated by dimethylthiazol-diphenyltetrazolium bromide (mtt), cell count and flow cytometry. |
2021-10-21 |
2023-08-12 |
Not clear |
| Shigeto Matsushita, Ko-Ichi Tada, Ko-Ichi Kawahara, Kazuhiro Kawai, Teruto Hashiguchi, Ikuro Maruyama, Takuro Kanekur. Advanced malignant melanoma responds to Prunus mume Sieb. Et Zucc (Ume) extract: Case report and in vitro study. Experimental and therapeutic medicine. vol 1. issue 4. 2021-10-21. PMID:22993577. |
in vitro studies, mtt assay, flow cytometric cell cycle analysis and immunofluorescence microscopy revealed that mk615 inhibited the growth of sk-mel28 cells in a dose-dependent manner, increased the proportion of cells in sub-g1 phase and induced apoptosis. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yoshioki Shiraishi, Kumiko Gotoh, Tomomi Towata, Tatsuya Shimasaki, Shinya Suzu, Akihiro Kojima, Seiji Okad. Therapeutic effects of γ-irradiation in a primary effusion lymphoma mouse model. Experimental and therapeutic medicine. vol 1. issue 1. 2021-10-21. PMID:23136597. |
an mtt assay and trypan blue exclusion assay revealed that irradiation significantly suppressed cell proliferation in the pel cell lines in a dose-dependent manner, and induced apoptosis. |
2021-10-21 |
2023-08-12 |
mouse |
| Asaf Taghiyev, Deguang Sun, Zhen Ming Gao, Rui Liang, Liming Wan. Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway. Experimental and therapeutic medicine. vol 4. issue 4. 2021-10-21. PMID:23170120. |
the mtt method was used to determine cell viability, and flow cytometry was used to assess the rate of apoptosis and the changes in mitochondrial membrane potential; the cell cycle was also analyzed. |
2021-10-21 |
2023-08-12 |
human |
| Ting Liu, Dan Liu, Jing Liu, Ji-Tao Song, Shan-Ling Gao, Hui Li, Li-Hong Hu, Bing-Rong Li. Effect of NF-κB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29. Experimental and therapeutic medicine. vol 4. issue 4. 2021-10-21. PMID:23170132. |
cell morphology was observed using inverted microscopy, and cell viability and apoptosis were assessed using the mtt assay and flow cytometry, respectively. |
2021-10-21 |
2023-08-12 |
Not clear |
| Kunpeng Zhao, Yan'ge Wang, Xueyin Wang, Yugang Wang, Yuanfang M. Tagged and untagged TRAIL show different activity against tumor cells. Oncology letters. vol 4. issue 6. 2021-10-21. PMID:23205127. |
we compared the abilities of the proteins to bind to death receptor 5 (dr5) by elisa and to induce apoptosis in a normal liver cell line (chang liver) and a human t-lymphocyte leukemia cell line (jurkat) by mtt assay, gr staining and facs. |
2021-10-21 |
2023-08-12 |
human |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
in vitro, a549 human lung adenocarcinoma cells were treated with ns, lip-null, etoposide, lip-pvax-m or lip-phtert-m, and examined for cell viability through mtt assays or for apoptosis by flow cytometry and tunel assays. |
2021-10-21 |
2023-08-12 |
mouse |
| Ling Liu, Liansheng Gong, Yangde Zhang, Nianfeng L. Glycolysis in Panc-1 human pancreatic cancer cells is inhibited by everolimus. Experimental and therapeutic medicine. vol 5. issue 1. 2021-10-21. PMID:23251295. |
cell proliferation and apoptosis were evaluated by mtt and flow cytometric analyses. |
2021-10-21 |
2023-08-12 |
human |
| Xiao-Man Xu, Yi Zhang, Dan Qu, Hong-Bo Liu, Xiu Gu, Guang-Yu Jiao, Li Zha. Combined anticancer activity of osthole and cisplatin in NCI-H460 lung cancer cells in vitro. Experimental and therapeutic medicine. vol 5. issue 3. 2021-10-21. PMID:23404433. |
to determine whether osthole enhances the anticancer effect of cisplatin in human lung cancer, we treated nci-h460 cells with osthole alone or in combination with cisplatin and evaluated cell growth and apoptosis using 3-(4,5-dimethyl thiazol-2yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry and fluorescence microscopy. |
2021-10-21 |
2023-08-12 |
human |
| Yu Gu, Shen-Lin Liu, Wen-Zheng Ju, Chang-Yin Li, Peng Ca. Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells. Oncology letters. vol 5. issue 2. 2021-10-21. PMID:23420047. |
in this study, cell viability and apoptosis of ragap-treated sw480 cells was evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry and 4',6-diamidino-2-phenylindole (dapi) staining. |
2021-10-21 |
2023-08-12 |
human |
| Min Fan, Xinying Li, Wei Jiang, Yun Huang, Jingdong Li, Zhiming Wan. A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells. Experimental and therapeutic medicine. vol 5. issue 4. 2021-10-21. PMID:23599737. |
cell growth, cell cycle transition and apoptosis were measured by mtt assay and flow cytometry. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yali Song, Gong Zhang, Xiulan Zhu, Zhanjun Pang, Fuqi Xing, Song Qua. Overexpression of the hydatidiform mole-related gene F10 inhibits apoptosis in A549 cells through downregulation of BCL2-associated X protein and caspase-3. Oncology letters. vol 4. issue 3. 2021-10-21. PMID:23741243. |
untransfected a549, a549-f10 or a549-empty cells were examined using the mtt cell proliferation assay and the tunel-fitc/hoechst 33258 apoptosis assay. |
2021-10-21 |
2023-08-12 |
human |
| Yong Chen, Ying Gao, Ye Tian, DA-Li Tia. PRKACB is downregulated in non-small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP-A2 cells. Oncology letters. vol 5. issue 6. 2021-10-21. PMID:23833645. |
a plasmid containing full-length prkacb was transfected into ltep-a2 cells to further investigate the effects of prkacb overexpression on proliferation, apoptosis and invasion of the transfected cells, which were examined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), colony formation, flow cytometry and transwell assays. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yubin Mao, Jinfei Xu, Gang Song, Nini Zhang, Hao Yi. Twist2 promotes ovarian cancer cell survival through activation of Akt. Oncology letters. vol 6. issue 1. 2021-10-21. PMID:23946798. |
dfo-induced apoptosis was examined by fluorescence microscopy, mtt assays and flow cytometry. |
2021-10-21 |
2023-08-12 |
human |
| Chuantao Suo, Libo Sun, Shuang Yan. Alpinetin activates the δ receptor instead of the κ and μ receptor pathways to protect against rat myocardial cell apoptosis. Experimental and therapeutic medicine. vol 7. issue 1. 2021-10-21. PMID:24348774. |
the mtt method was used to evaluate cell viability and annexin v-fluorescein isothiocyanate (fitc)/propidium iodide (pi) staining was used to analyze apoptosis. |
2021-10-21 |
2023-08-12 |
rat |
| Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Ta. JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen-activated protein kinase signaling pathways. Experimental and therapeutic medicine. vol 7. issue 6. 2021-10-21. PMID:24926382. |
western blot analysis was conducted to observe the effect of jwa on apoptosis and the regulatory effect of jwa on proliferation was determined using a thiazolyl blue tetrazolium bromide (mtt) assay. |
2021-10-21 |
2023-08-13 |
human |
| Chen-Feng Ji, Yu-Bin J. Apoptosis of human gastric cancer SGC-7901 cells induced by podophyllotoxin. Experimental and therapeutic medicine. vol 7. issue 5. 2021-10-21. PMID:24940431. |
mtt assays and flow cytometry were used to evaluate the effects of podophyllotoxin on the proliferation and apoptosis of sgc-7901 cells, while fluorescence inverted microscopy was used to observe the morphology of sgc-7901 cells that had been dyed with hoechst 33258. |
2021-10-21 |
2023-08-13 |
human |