| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wene Wei, Qijing Guo, Cuiping Guo, Xianshu Cui, Xuemei Ma, Xianliang Shen, Yushuang Lu. Ginsenoside Rh2 Suppresses Metastasis and Growth of Colon Cancer via miR-491. Journal of oncology. vol 2021. 2021-10-05. PMID:34603449. |
first, ginsenoside rh2 chitosan tripolyphosphate (cs-rh2-tpp) nanoparticles (nps) were constructed, and mtt, transwell, scratch adhesion, and flow cytometry assays were carried out for determining the impact of cs-rh2-tpp at various concentrations on growth, metastasis, and apoptosis of colon cancer cells (cccs). |
2021-10-05 |
2023-08-13 |
human |
| Renata Dobrucka, Aleksandra Romaniuk-Drapała, Mariusz Kaczmare. Biologically synthesized of Au/Pt/ZnO nanoparticles using Arctium lappa extract and cytotoxic activity against leukemia. Biomedical microdevices. vol 22. issue 4. 2021-10-04. PMID:33037930. |
this work also assessed the cytotoxicity of au/pt/zno nanoparticles by means of mtt assay, and analyzed apoptosis as well as the influence of the cultivation time and concentration of au/pt/zno nanoparticles on the percentage of dead cells. |
2021-10-04 |
2023-08-13 |
Not clear |
| Raja David Isac Evangeline Breeta, Viswanathan Mariammal Berlin Grace, Devarajan David Wilso. Methyl Palmitate-A suitable adjuvant for Sorafenib therapy to reduce in vivo toxicity and to enhance anti-cancer effects on hepatocellular carcinoma cells. Basic & clinical pharmacology & toxicology. vol 128. issue 3. 2021-10-04. PMID:33128309. |
the combination of sorafenib (4.5 µmol/l) with methyl palmitate (3 mmol/l) significantly enhanced anti-cancer effects on hep-g2 cell line by increasing cytotoxicity (p ≤ .05 in mtt assay; p ≤ .01 in trypan blue assay), apoptosis (p ≤ .05) and decreasing the metastatic migration (p ≤ .01) than sorafenib alone treatment. |
2021-10-04 |
2023-08-13 |
human |
| G Ávila, D De Leonardis, G Grilli, C Lecchi, F Cecilian. Anti-inflammatory activity of citrus pectin on chicken monocytes' immune response. Veterinary immunology and immunopathology. vol 237. 2021-10-04. PMID:34023617. |
the effects of different cp concentrations on cells' apoptosis and viability were assessed by measuring caspase-3 and -7 and the cells' metabolic activity (mtt assay), respectively. |
2021-10-04 |
2023-08-13 |
chicken |
| Ashraf Al Madhoun, Dania Haddad, Mustafa Al Tarrah, Sindhu Jacob, Waleed Al-Ali, Rasheeba Nizam, Lavina Miranda, Fatema Al-Rashed, Sardar Sindhu, Rasheed Ahmad, Milad S Bitar, Fahd Al-Mull. Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34088951. |
cell proliferation and apoptosis were evaluated by mtt assays and flow cytometry, gene expression was assessed by affymetrix microarray, signaling pathway perturbations were assessed in silico, and key regulatory proteins were validated by western blotting. |
2021-10-04 |
2023-08-13 |
Not clear |
| Hongyan Ma, Lu Ba. Effect of Polygonatum odoratum ethanol extract on high glucose-induced tubular epithelial cell apoptosis and oxidative stress. Pakistan journal of pharmaceutical sciences. vol 34. issue 3(Special). 2021-10-04. PMID:34602390. |
hk-2 cell activity and apoptosis were detected by mtt method and flow cytometry, respectively. |
2021-10-04 |
2023-08-13 |
Not clear |
| Yanlin Jin, Yi Zhang, Xiaoming Lu. circRNA_PTPRA functions as a sponge of miR-582-3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis. Experimental and therapeutic medicine. vol 22. issue 5. 2021-10-02. PMID:34594413. |
hcc cell viability, apoptosis, migration and invasion were measured using mtt, flow cytometry and transwell assays, respectively. |
2021-10-02 |
2023-08-13 |
human |
| Shiyue Hu, Yunpeng Hao, Xiao Zhang, Yaping Yang, Meiling Liu, Nan Wang, Tong-Cun Zhang, Hongpeng H. Lacticaseibacillus casei LH23 Suppressed HPV Gene Expression and Inhibited Cervical Cancer Cells. Probiotics and antimicrobial proteins. 2021-10-02. PMID:34599740. |
with mtt, edu staining, and tunel staining assays, lacticaseibacillus casei lh23 was shown to suppress the proliferation and induced the apoptosis of cervical cancer cells. |
2021-10-02 |
2023-08-13 |
mouse |
| Yu-Hua Ding, Run-Xin Miao, Qiang Zhan. Hypaphorine exerts anti-inflammatory effects in sepsis induced acute lung injury via modulating DUSP1/p38/JNK pathway. The Kaohsiung journal of medical sciences. vol 37. issue 10. 2021-10-01. PMID:34250720. |
beas-2b cell viability and apoptosis was testified by the mtt assay and flow cytometry. |
2021-10-01 |
2023-08-13 |
rat |
| Per-Christian Berg, Åse Mari Larsen Hansson, Øystein Røsand, Gurdeep Marwarha, Morten Andre Høyda. Overexpression of Neuron-Derived Orphan Receptor 1 (NOR-1) Rescues Cardiomyocytes from Cell Death and Improves Viability after Doxorubicin Induced Stress. Biomedicines. vol 9. issue 9. 2021-10-01. PMID:34572418. |
to determine the protective effect of nor-1 in cms stressed with dox challenge, we overexpressed nor-1 in ac16 human cms treated with 5 µm dox for 12 h or the respective vehicle control, followed by performing lactate dehydrogenase (ldh) activity, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), and caspase-3 activity assays to measure cell death, cell viability, and apoptosis, respectively. |
2021-10-01 |
2023-08-13 |
human |
| Fadwa Al Mughairbi, Rukhsana Nawaz, Faisal Khan, Amina Hassan, Nailah Mahmood, Heba Tageldeen Ahmed, Alia Alshamali, Sagheer Ahmed, Asma Bashi. Neuroprotective effects of Bhilawanol and Anacardic acid during glutamate-induced neurotoxicity. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 29. issue 9. 2021-10-01. PMID:34588850. |
cell viability, toxicity and calcium influx were determined by mtt assay, ldh release assay and fluo-3 imaging while apoptosis was assayed by caspase-3 and bcl-2 gene expression. |
2021-10-01 |
2023-08-13 |
rat |
| Dandan Huang, Cuimei L. circ-ACACA promotes proliferation, invasion, migration and glycolysis of cervical cancer cells by targeting the miR-582-5p/ERO1A signaling axis. Oncology letters. vol 22. issue 5. 2021-09-30. PMID:34584570. |
circ-acaca expression was subsequently knocked down to evaluate its effects on the viability, proliferation, apoptosis, invasion and migration of cc cells using mtt, colony formation, tunel, transwell and wound healing assays, respectively. |
2021-09-30 |
2023-08-13 |
Not clear |
| Mohamed El-Mesery, Axel Seher, Mohamed El-Shafey, Mohamed El-Dosoky, Farid A Badri. Repurposing of quinoline alkaloids identifies their ability to enhance doxorubicin-induced sub-G0/G1 phase cell cycle arrest and apoptosis in cervical and hepatocellular carcinoma cells. Biotechnology and applied biochemistry. vol 68. issue 4. 2021-09-29. PMID:32757395. |
cell viability was analyzed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and the alkaloids ability to enhance dox-induced apoptosis was explored using western blotting analysis. |
2021-09-29 |
2023-08-13 |
human |
| Jianqiang Ma, Yifan Wu, Ying H. Silencing circRNA LRP6 down-regulates PRMT1 to improve the streptozocin-induced pancreatic β-cell injury and insulin secretion by sponging miR-9-5p. Journal of bioenergetics and biomembranes. vol 53. issue 3. 2021-09-29. PMID:33826088. |
after knocking down circlrp6, the cell viability and apoptosis were respectively measured by mtt and tdt-mediated dutp nick-end labeling (tunel) staining, and insulin release and oxidative stress were respectively measured by enzyme-linked immunosorbent assay (elisa) and corresponding kits. |
2021-09-29 |
2023-08-13 |
Not clear |
| Shoubin Cui, Fengling L. RHPN1‑AS1 promotes ovarian carcinogenesis by sponging miR‑6884‑5p thus releasing TOP2A mRNA. Oncology reports. vol 46. issue 4. 2021-09-29. PMID:34414458. |
brdu, mtt, colony formation and cell adhesion assays, caspase‑3 activity, flow cytometry and wound healing assay were employed to assess cell proliferation, viability, colony number, adhesion, apoptosis and migration in ovarian cancer, respectively. |
2021-09-29 |
2023-08-13 |
human |
| Zahra Mohamadzade, Bahram M Soltani, Zahra Ghaemi, Parisa Hoseinpou. Cell specific tumor suppressor effect of Hsa-miR-1226-3p through downregulation of HER2, PIK3R2, and AKT1 genes. The international journal of biochemistry & cell biology. vol 134. 2021-09-28. PMID:33675995. |
the reduced survival and increased apoptosis rate of these cells was also verified through mtt, annexin v-fitc and live-dead cell staining assays. |
2021-09-28 |
2023-08-13 |
Not clear |
| Wei Yin, Jianfeng Xu, Yanjiao Ma. Synergistic effects of autophagy inhibitors combined with cisplatin against cisplatin-resistant nasopharyngeal cancer cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 99. issue 3. 2021-09-28. PMID:34038188. |
cell viability was determined via mtt (colorimetric) and colony-forming assays, and the rate of apoptosis was determined using propidium iodide (pi) and annexin v double-staining. |
2021-09-28 |
2023-08-13 |
mouse |
| Yan Guo, Fen Du, Yi-Lan Tan, Jun Luo, Dan Xiong, Wei-Tao Son. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 99. issue 4. 2021-09-28. PMID:34319836. |
cell proliferation, apoptosis, and angiogenesis in the oir model mice were measured using mtt assays, flow cytometry, and matrigel assays, respectively. |
2021-09-28 |
2023-08-13 |
mouse |
| Mahboobeh Nazari, Arash Minai-Tehrani, Samira Mousavi, Saeideh Zamani Koukhaloo, Rahman Emamzade. Development of recombinant biomimetic nano-carrier for targeted gene transfer to HER3 positive breast cancer. International journal of biological macromolecules. vol 189. 2021-09-28. PMID:34455002. |
our affibody-based platform containing a rigid linker and one rala unit presents an adequate transfection efficacy and low toxicity (based on mtt and apoptosis assays), however, the platform containing two rala units and a flexible linker demonstrated high transfection efficacy while having modest toxicity in her3 positive breast cancer cells. |
2021-09-28 |
2023-08-13 |
human |
| Muhammad Daniyal, Yongbei Liu, Yupei Yang, Feng Xiao, Jialong Fan, Huanghe Yu, Yixing Qiu, Bin Liu, Wei Wang, Qin Yuhu. Anti-gastric cancer activity and mechanism of natural compound "Heilaohulignan C" isolated from Kadsura coccinea. Phytotherapy research : PTR. vol 35. issue 7. 2021-09-27. PMID:34155704. |
mtt test demonstrated the cytotoxicity of bgc-823 cells, calcein am/propidium iodide (pi) examine indicated increment dead cells proportion with a high dose of b-6, flow cytometry (facs) measure showed that b-6 influenced gastric cancer cells by initiating apoptosis. |
2021-09-27 |
2023-08-13 |
mouse |