| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Wang, Zhigang Hu, Weiyuan Ma, Yong Niu, Jingwei Su, Lingxiang Zhang, Pengxin Zha. Signal transducer and activator of transcription 3 inhibition alleviates resistance to BRAF inhibition in anaplastic thyroid cancer. Investigational new drugs. vol 39. issue 3. 2021-10-13. PMID:33245464. |
tc cells were treated with vemurafenib and cell apoptosis and viability were analyzed by flow cytometry and mtt assay. |
2021-10-13 |
2023-08-13 |
mouse |
| Tianjun Wei, Xiangming Zh. Knockdown of ANXA10 inhibits proliferation and promotes apoptosis of papillary thyroid carcinoma cells by down-regulating TSG101 thereby inactivating the MAPK/ERK signaling pathway. Journal of bioenergetics and biomembranes. vol 53. issue 4. 2021-10-12. PMID:34032966. |
subsequently, ptc cell line bcpap was silenced with anxa10 followed by tsg101 overexpression or not, and then cell proliferation, apoptosis and mitogen-activated protein kinase (mapk) signaling expression were assessed via mtt, colony formation, immunofluorescence staining, tunel staining and western blotting assays. |
2021-10-12 |
2023-08-13 |
Not clear |
| Liang Cheng, Huifeng Cao, Jianbo Xu, Mo Xu, Wenjie He, Wenjing Zhang, Longxin Dong, Dayin Che. Circ_RPL23A acts as a miR-1233 sponge to suppress the progression of clear cell renal cell carcinoma by promoting ACAT2. Journal of bioenergetics and biomembranes. vol 53. issue 4. 2021-10-12. PMID:34036483. |
cell cycle progression, apoptosis, cell viability, invasion and migration, which were respectively conducted by using flow cytometry, 3-(4, 5-dimethylthiazol-2-y1)-2, 5-diphenyl tetrazolium bromide (mtt), transwell assays. |
2021-10-12 |
2023-08-13 |
Not clear |
| Chunju Zheng, Ting Lu, Zhimin Fa. miR-200b-3p alleviates TNF-α-induced apoptosis and inflammation of intestinal epithelial cells and ulcerative colitis progression in rats via negatively regulating KHDRBS1. Cytotechnology. vol 73. issue 5. 2021-10-12. PMID:34629748. |
mtt and flow cytometry were respectively performed to detect cell proliferation and apoptosis. |
2021-10-12 |
2023-08-13 |
rat |
| Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuan. MicroRNA-18a-5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression. Experimental and therapeutic medicine. vol 22. issue 5. 2021-10-12. PMID:34630672. |
cell proliferation was detected by an mtt assay, while cell apoptosis was measured by flow cytometry. |
2021-10-12 |
2023-08-13 |
human |
| Jie Wang, Jingyun Zha, Xiaolin Wan. Knockdown of lncRNA NUTM2A-AS1 inhibits lung adenocarcinoma cell viability by regulating the miR-590-5p/METTL3 axis. Oncology letters. vol 22. issue 5. 2021-10-12. PMID:34630705. |
the expression levels of nutm2a-as1 and mir-590-5p in lung cancer cells, and the effects of nutm2a-as1 on cell viability and apoptosis were determined using mtt assays and flow cytometry, respectively. |
2021-10-12 |
2023-08-13 |
Not clear |
| Katayon Hemmati, Navid Ahmadi Nasab, Saeed Hesaraki, Nader Nezafat. Journal of biomaterials science. Polymer edition. vol 32. issue 10. 2021-10-11. PMID:33820489. |
for this purpose, the rate of cytotoxicity by the methyl-thiazol-tetrazolium (mtt) assay and the rate of apoptosis induction by the acridine orange and ethidium bromide (ao/eb) staining method on the brain carcinoma u87mg cell line were investigated. |
2021-10-11 |
2023-08-13 |
Not clear |
| Khadijeh Barzaman, Mitra Samadi, Shima Moradi-Kalbolandi, Keivan Majidzadeh-A, Malihe Salehi, Neda Jalili, Mir Hadi Jazayeri, Samaneh Khorammi, Behrad Darvishi, Vahid Siavashi, Mahdi Shekarabi, Leila Farahman. Development of a recombinant anti-VEGFR2-EPCAM bispecific antibody to improve antiangiogenic efficiency. Experimental cell research. vol 405. issue 2. 2021-10-11. PMID:34090863. |
then, its anti-proliferative potential was indicated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and apoptosis assay to evaluate inhibitory effects of the antibody on tumor cells. |
2021-10-11 |
2023-08-13 |
Not clear |
| Letizia Giampietro, Marialucia Gallorini, Nicola Gambacorta, Alessandra Ammazzalorso, Barbara De Filippis, Alice Della Valle, Marialuigia Fantacuzzi, Cristina Maccallini, Adriano Mollica, Amelia Cataldi, Orazio Nicolotti, Rosa Amoros. Synthesis, structure-activity relationships and molecular docking studies of phenyldiazenyl sulfonamides as aromatase inhibitors. European journal of medicinal chemistry. vol 224. 2021-10-11. PMID:34365129. |
compounds 3b, 3f and 5f showed an aromatase inhibition in the micromolar range and were evaluated in vitro on the human breast cancer cell line mcf7 by mtt assay, cytotoxicity assay (ldh release), cell cycle analysis and apoptosis, revealing a dose-dependent inhibition profile. |
2021-10-11 |
2023-08-13 |
human |
| Lei Jin, Karrie Mei-Yee Kiang, Stephen Yin Cheng, Gilberto Ka-Kit Leun. Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O Laboratory investigation; a journal of technical methods and pathology. 2021-10-09. PMID:34625658. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flowcytometry and colony formation assays demonstrated that nct503 worked synergistically with tmz in suppressing gbm cell growth and inducing apoptosis in t98g and u118 cells in vitro. |
2021-10-09 |
2023-08-13 |
Not clear |
| Mohammad Satari, Fatemeh Javani Jouni, Parviz Abolmaleki, Homa Soleiman. Influence of Static Magnetic Field on HeLa and Huo2 Cells in the Presence of Aloe vera Extract. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue S1. 2021-10-08. PMID:33576207. |
mtt assay determined the ic50 value, and flow cytometry was employed to evaluate cell cycle distribution and apoptosis rates. |
2021-10-08 |
2023-08-13 |
Not clear |
| Yue He, Wenqiang Tao, Chao Shang, Chan Qi, Dexiang Ji, Wei Lu, Guoan Che. Xeroderma Pigmentosum group D suppresses proliferation and promotes apoptosis of HepG2 cells by downregulating ERG expression via the PPARγ pathway. International journal of experimental pathology. vol 102. issue 3. 2021-10-08. PMID:33993564. |
cell cycle and apoptosis were ascertained by flow cytometry, and cell viability was measured by mtt assay. |
2021-10-08 |
2023-08-13 |
human |
| Jian Zhang, Jie Xiang, Ting Liu, Xinwei Wang, Ying Tang, Yin Lian. miR-495 targets ROCK1 to inhibit lipopolysaccharides-induced WI-38 cells apoptosis and inflammation. The Kaohsiung journal of medical sciences. vol 36. issue 8. 2021-10-07. PMID:32237054. |
data from mtt (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) and flow cytometry assays showed that the decreased cell viability and induced cell apoptosis by lps treatment were also reversed by mir-495 over-expression. |
2021-10-07 |
2023-08-13 |
Not clear |
| Ying Xue, Ai-Zhong Wan. DJ-1 plays a neuroprotective role in SH-SY5Y cells by modulating Nrf2 signaling in response to lidocaine-mediated oxidative stress and apoptosis. The Kaohsiung journal of medical sciences. vol 36. issue 8. 2021-10-07. PMID:32363780. |
cell viability was measured by mtt assay, and apoptosis was measured by flow cytometry analysis. |
2021-10-07 |
2023-08-13 |
cat |
| Xinghai Chen, Debiao Son. LncRNA MEG3 Participates in Caerulein-Induced Inflammatory Injury in Human Pancreatic Cells via Regulating miR-195-5p/FGFR2 Axis and Inactivating NF-κB Pathway. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32856219. |
cell proliferation and apoptosis were detected by 3-(4, 5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay and flow cytometry assay, respectively. |
2021-10-07 |
2023-08-13 |
human |
| Bin Shan, Jia-Yan Li, Ya-Jiang Liu, Xiao-Bin Tang, Zheng Zhou, Liang-Xian Lu. LncRNA H19 Inhibits the Progression of Sepsis-Induced Myocardial Injury via Regulation of the miR-93-5p/SORBS2 Axis. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32996061. |
cell proliferation and apoptosis were detected by mtt assay and flow cytometry, respectively. |
2021-10-07 |
2023-08-13 |
human |
| Yujuan Qi, Kai Zhang, Peijun Li, Zhenhua W. Down-regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1. Inflammation. vol 44. issue 1. 2021-10-07. PMID:33064238. |
cell viability and apoptosis were respectively detected by mtt assay and flow cytometry. |
2021-10-07 |
2023-08-13 |
Not clear |
| Zhining Liu, Yimei Gu, Xiaohu Cheng, Heng Jiang, Yang Huang, Yingfeng Zhang, Gang Yu, Yunsheng Cheng, Lianbang Zho. Upregulation lnc-NEAT1 contributes to colorectal cancer progression through sponging miR-486-5p and activating NR4A1/Wnt/β-catenin pathway. Cancer biomarkers : section A of Disease markers. vol 30. issue 3. 2021-10-07. PMID:33337350. |
3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-2h-tetrazol-3-ium bromide (mtt) and flow cytometry assays were performed to evaluate proliferation and apoptosis of colorectal cancer cells, respectively. |
2021-10-07 |
2023-08-13 |
Not clear |
| Haider A Alkafaji, Ahmed Raji, Heshu S Rahman, Angelina O Zekiy, Ali Adili, Mohammadmahdi Jalili, Tahereh Hojjatipour, Angel Cid-Arregui, Navid Shomali, Saeed Tarzi, Rozita Tamjidifar, Ramin Heshmati, Faroogh Marofi, Morteza Akbari, Ali Hasanzadeh, Mina Deljavanghodrati, Mostafa Jarahian, Siamak Sandoghchian Shotorban. Up-regulation of KISS1 as a novel target of Let-7i in melanoma serves as a potential suppressor of migration and proliferation in vitro. Journal of cellular and molecular medicine. vol 25. issue 14. 2021-10-05. PMID:34096173. |
in the in vitro part of the study, let-7i mimics were transfected and the impact of its restoration on target gene expression, proliferation, migration and apoptosis of sk-mel-3 melanoma cell line was assessed by real-time pcr and western blotting, mtt assay, wound-healing assay and flow cytometry, respectively. |
2021-10-05 |
2023-08-13 |
Not clear |
| Hui Xiong, Jinsong Yu, Guangwei Jia, Yang Su, Jianliang Zhang, Qiu Xu, Xiaoxiong Su. Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells. Human cell. vol 34. issue 6. 2021-10-05. PMID:34346032. |
cell proliferation, apoptosis, and invasion were evaluated using mtt, flow cytometry analysis, and transwell invasion assay, respectively. |
2021-10-05 |
2023-08-13 |
Not clear |