| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Jun Duan, Xi Zhang, Niu Ding, Ji-Yan Zhang, Yan-Ping Che. LncRNA NEAT1 regulates MMP-16 by targeting miR-200a/b to aggravate inflammation in asthma. Autoimmunity. vol 54. issue 7. 2021-11-01. PMID:34448644. |
mtt and flow cytometry assays were employed to determine cell proliferation and apoptosis, respectively. |
2021-11-01 |
2023-08-13 |
Not clear |
| Shenouda G Elia, Ahmed A Al-Karmalawy, Mohamed Y Nasr, Mohamed F Elsha. Loperamide potentiates doxorubicin sensitivity in triple-negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl-2: In vitro and molecular docking study. Journal of biochemical and molecular toxicology. 2021-11-01. PMID:34719826. |
therefore, we examined the effects of dxr alone or in combination with lpr on mda-md-231 cells viability using mtt assay, cell cycle, and apoptosis by flow cytometry, and the expression of the mdr-related genes (mdr1 and jnk1) and cell cycle/survival genes (p21, mtor, and bcl-2) by quantitative reverse transcription polymerase chain reaction. |
2021-11-01 |
2023-08-13 |
Not clear |
| Wei Yang, Yunbin Chen, Chao Huang, Wenjian Wang, Congfu Huang, Yuanguang L. MiR-18a Inhibits PI3K/AKT Signaling Pathway to Regulate PDGF BB-Induced Airway Smooth Muscle Cell Proliferation and Phenotypic Transformation. Physiological research. vol 70. issue 6. 2021-10-30. PMID:34717064. |
cell proliferation, apoptosis and migration were detected by mtt, flow cytometry and transwell, respectively; the expression of contractile phenotype marker proteins (sm-22alpha, alpha-sm-actin, calponin) and key molecules of the phosphatidylinositol 3-kinase (pi3k)/akt pathway (pi3k, p-pi3k, akt and p-akt) in asmcs were detected by western blot. |
2021-10-30 |
2023-08-13 |
human |
| Lei Bi, Chunguang Zhang, Yuan Yao, Zhao H. Circ-HIPK3 regulates YAP1 expression by sponging miR-381-3p to promote oral squamous cell carcinoma development. Journal of biosciences. vol 46. 2021-10-29. PMID:33737493. |
cell proliferation, apoptosis, invasion and migration were measured by mtt assay, flow cytometry, or transwell assay. |
2021-10-29 |
2023-08-13 |
human |
| Pengcheng Dou, Guangshuang Tan, Zhihua Fan, Jiatong Xiao, Chaoran Shi, Zhengjun Li. MicroRNA-9 facilitates hypoxia-induced injury and apoptosis in H9c2 cells via targeting CDK8. Journal of biosciences. vol 46. 2021-10-29. PMID:33737500. |
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt), lactate dehydrogenase (ldh) measurement, flow cytometry assays were conducted to detect cell proliferation, the release of ldh and cell apoptosis, respectively. |
2021-10-29 |
2023-08-13 |
Not clear |
| Wei Hong, Lichen Tang, Rui Ge, Weiping Li, Xiaoyong Shen, Lixia Hong, Xiaoya X. Persistent Abnormal Immunocytes Induced Systemic Bone Loss in Locally Irradiated Rats. Calcified tissue international. vol 109. issue 6. 2021-10-29. PMID:34191050. |
the proliferation and apoptosis characteristics of co-cultured bone marrow-derived mesenchymal stem cells (bmscs) were detected by mtt assay and pi/annexin v-fitc staining, respectively, and the differentiation of bmscs was measured according to alkaline phosphatase (alp) staining, alizarin red staining, and oil red o staining and by evaluating the mrna expression of alp, osteocalcin (ocn), osteopontin (opn), collagen i, runx2, and pparγ. |
2021-10-29 |
2023-08-13 |
rat |
| Tahany Saad Abdelwahab, Rania Ellisy Abdelhamed, Eman Noaman Ali, Nahla Ahmed Mansour, Mohga Shafik Abdall. Evaluation of Silver Nanoparticles Caffeic Acid Complex Compound as New Potential Therapeutic Agent against Cancer Incidence in Mice. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue 10. 2021-10-29. PMID:34710995. |
the present work was designed to study the effect of new conjugated caffeic and folic acid with silver nanoparticles with definite molecular size applied with and without gamma radiation exposure, as an antitumor agent against experimentally induced ehrlich tumor and attempted to identify their potential molecular mechanisms of action throughout determination of anti-tumor activities using mtt cytotoxic assay against two human carcinoma cell lines in vitro, such as apoptosis analysis by flow cytometry through caspase-8, caspase-3 and tnf determination in vivo. |
2021-10-29 |
2023-08-13 |
mouse |
| Shuqiu Chen, Haihong Ye, Fanger Gong, Suming Mao, Cong Li, Bin Xu, Yu Ren, Rui Y. Ginsenoside compound K exerts antitumour effects in renal cell carcinoma via regulation of ROS and lncRNA THOR. Oncology reports. vol 45. issue 4. 2021-10-28. PMID:33649829. |
the effects of ck on the proliferation, migration, invasion, cell cycle and apoptosis of rcc cell lines (caki‑1 and 768‑o) were investigated using mtt, wound healing, transwell and flow cytometry assays, respectively. |
2021-10-28 |
2023-08-13 |
Not clear |
| Xianbao Huang, Ling Qi, Wei Lu, Ziye Li, Wuping Li, Fei L. MYCN contributes to the sensitization of acute myelogenous leukemia cells to cisplatin by targeting SRY-box transcription factor 4. Bioengineered. 2021-10-28. PMID:34709111. |
mtt and flow cytometry assays were performed to estimate the viability and apoptosis of aml cell. |
2021-10-28 |
2023-08-13 |
mouse |
| Xingli Liu, Wei Song, Xiangmin Zhang, Fangmin Long, Junkun Yin, Xiao He, Liang L. Downregulating LncRNA XIST attenuated contrast-induced nephropathy injury via regulating miR-133a-3p/NLRP3 axis. Journal of thrombosis and thrombolysis. vol 52. issue 2. 2021-10-27. PMID:33387208. |
the cells viability and apoptosis were respectively detected by mtt assay and flow cytometry. |
2021-10-27 |
2023-08-13 |
rat |
| Kunpeng Wu, Ying Chen, Deming Wang, Kui H. MicroRNA-520d-3p alleviates hypoxia/reoxygenation-induced damage in human cardiomyocytes by targeting ATG-12. Journal of thrombosis and thrombolysis. vol 52. issue 2. 2021-10-27. PMID:33389611. |
mtt method and annexin v-fitc flow cytometry were employed to measure the viability and apoptosis of h/r treated hcm. |
2021-10-27 |
2023-08-13 |
human |
| Huajie Cai, Yihu Zheng, Zhengde Wen, Yingnan Yang, Shouzhang Yang, Qiyu Zhan. LncRNA AIRN influences the proliferation and apoptosis of hepatocellular carcinoma cells by regulating STAT1 ubiquitination. Archives of pharmacal research. vol 44. issue 4. 2021-10-26. PMID:33759138. |
the cell transfection, mtt and flow cytometry assays expounded that the lncrna airn/stat1 axis was bound up with the regulation of the proliferation and apoptosis of hcc cells. |
2021-10-26 |
2023-08-13 |
human |
| Natalia Magdalena Lisiak, Izabela Lewicka, Mariusz Kaczmarek, Jacek Kujawski, Barbara Bednarczyk-Cwynar, Lucjusz Zaprutko, Blazej Rubi. Oleanolic Acid's Semisynthetic Derivatives HIMOXOL and Br-HIMOLID Show Proautophagic Potential and Inhibit Migration of HER2-Positive Breast Cancer Cells In Vitro. International journal of molecular sciences. vol 22. issue 20. 2021-10-26. PMID:34681931. |
viability tests, cell cycle assessment, evaluation of apoptosis, autophagy, and adhesion/migration processes were performed using mtt, clonogenic, cytofluorometry, western blot, and qpcr. |
2021-10-26 |
2023-08-13 |
human |
| Emma Rodriguez, Guangsheng Pei, Sang T Kim, Alexis German, Prema Robinso. Substance P Antagonism as a Novel Therapeutic Option to Enhance Efficacy of Cisplatin in Triple Negative Breast Cancer and Protect PC12 Cells against Cisplatin-Induced Oxidative Stress and Apoptosis. Cancers. vol 13. issue 15. 2021-10-23. PMID:34359773. |
we determined that treatment with aprepitant, an sp-receptor antagonist decreased cisplatin-induced, loss of viability (studied by mtt assay), production of reactive oxygen species (by dcfda assay) and apoptosis (by flow-cytometry) in pc12 cells while it was increased in the two tnbc cells. |
2021-10-23 |
2023-08-13 |
Not clear |
| Wang Jun, Ouyang Shaobo, Zhang Xianhua, Zhao Siyu, Cheng Mingyang, Fan Xin, Cai Ying, Liao La. Deregulation of hsa_circ_0001971/miR-186 and hsa_circ_0001874/miR-296 signaling pathways promotes the proliferation of oral squamous carcinoma cells by synergistically activating SHP2/PLK1 signals. Scientific reports. vol 11. issue 1. 2021-10-23. PMID:34663837. |
mtt assay and fcm assay were performed to investigate the synergistic effect of circ_0001971 and circ_0001874 on cell proliferation and apoptosis. |
2021-10-23 |
2023-08-13 |
Not clear |
| Qingshan Ji, Jing Han, Lisong Wang, Jiajia Liu, Yiran Dong, Kai Zhu, Lei Sh. MicroRNA-34a promotes apoptosis of retinal vascular endothelial cells by targeting SIRT1 in rats with diabetic retinopathy. Cell cycle (Georgetown, Tex.). vol 19. issue 21. 2021-10-22. PMID:33064974. |
mtt assay and flow cytometry were performed to detect proliferation and apoptosis. |
2021-10-22 |
2023-08-13 |
rat |
| Bo Qin, Meng Dong, Zhengyang Wang, Jiajia Wan, Yingying Xie, Yi Jiao, Dan Ya. Long non‑coding RNA CASC15 facilitates esophageal squamous cell carcinoma tumorigenesis via decreasing SIM2 stability via FTO‑mediated demethylation. Oncology reports. vol 45. issue 3. 2021-10-22. PMID:33650646. |
cell proliferation and apoptosis were evaluated via mtt, flow cytometry and caspase‑3 activity assays, respectively. |
2021-10-22 |
2023-08-13 |
mouse |
| Lu Chang, Rui Zhou, Yihan He, Mei Meng, Jinhang Hu, Yanru Liu, Yalei Pan, Zhishu Tang, Zhenggang Yu. Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell. Molecular medicine reports. vol 24. issue 2. 2021-10-22. PMID:34080021. |
the effect of rpmtg on the proliferation, cell cycle progression and apoptosis of hct116 and sw620 cells were detected by mtt, flow cytometry and western blotting assays, and it was demonstrated that rpmtg could inhibit the proliferation of hct116 and sw620 cells with ic50 values of 315.8 and 355.1 |
2021-10-22 |
2023-08-13 |
Not clear |
| Chenguang Bai, Xiaohong Liu, Jian-Ming Zheng, Cen Qiu, Yan Zhu, Jingjing Xu, Jing Zhao, Dalie M. A novel PDGFRA mutation in gastrointestinal stromal tumours, L839P, is sensitive to imatinib in vitro. Oncology letters. vol 3. issue 5. 2021-10-21. PMID:22783407. |
the responses of cells with pdgfra(wild), pdgfra(l839p) and pdgfra(d842v) mutants to imatinib were determined by methyl thiazolyl tetrazolium (mtt) assay, western blotting and apoptosis assays. |
2021-10-21 |
2023-08-12 |
Not clear |
| Nannan Tong, Jie Zhang, Youran Chen, Zhubo Li, Yonghuang Luo, Hua Zuo, Xiaoyan Zha. Berberine sensitizes mutliple human cancer cells to the anticancer effects of doxorubicin in vitro. Oncology letters. vol 3. issue 6. 2021-10-21. PMID:22783430. |
the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-tetrazolium bromide (mtt) assay was used to detect the cell viability of a549, hela and hepg2 cells after each cell line was treated with dox, ber or a combination of dox and ber for 24 h. apoptosis was evaluated by acridine orange staining. |
2021-10-21 |
2023-08-12 |
human |