| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Khadijeh Barzaman, Mitra Samadi, Shima Moradi-Kalbolandi, Keivan Majidzadeh-A, Malihe Salehi, Neda Jalili, Mir Hadi Jazayeri, Samaneh Khorammi, Behrad Darvishi, Vahid Siavashi, Mahdi Shekarabi, Leila Farahman. Development of a recombinant anti-VEGFR2-EPCAM bispecific antibody to improve antiangiogenic efficiency. Experimental cell research. vol 405. issue 2. 2021-10-11. PMID:34090863. |
then, its anti-proliferative potential was indicated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and apoptosis assay to evaluate inhibitory effects of the antibody on tumor cells. |
2021-10-11 |
2023-08-13 |
Not clear |
| Letizia Giampietro, Marialucia Gallorini, Nicola Gambacorta, Alessandra Ammazzalorso, Barbara De Filippis, Alice Della Valle, Marialuigia Fantacuzzi, Cristina Maccallini, Adriano Mollica, Amelia Cataldi, Orazio Nicolotti, Rosa Amoros. Synthesis, structure-activity relationships and molecular docking studies of phenyldiazenyl sulfonamides as aromatase inhibitors. European journal of medicinal chemistry. vol 224. 2021-10-11. PMID:34365129. |
compounds 3b, 3f and 5f showed an aromatase inhibition in the micromolar range and were evaluated in vitro on the human breast cancer cell line mcf7 by mtt assay, cytotoxicity assay (ldh release), cell cycle analysis and apoptosis, revealing a dose-dependent inhibition profile. |
2021-10-11 |
2023-08-13 |
human |
| Lei Jin, Karrie Mei-Yee Kiang, Stephen Yin Cheng, Gilberto Ka-Kit Leun. Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O Laboratory investigation; a journal of technical methods and pathology. 2021-10-09. PMID:34625658. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flowcytometry and colony formation assays demonstrated that nct503 worked synergistically with tmz in suppressing gbm cell growth and inducing apoptosis in t98g and u118 cells in vitro. |
2021-10-09 |
2023-08-13 |
Not clear |
| Mohammad Satari, Fatemeh Javani Jouni, Parviz Abolmaleki, Homa Soleiman. Influence of Static Magnetic Field on HeLa and Huo2 Cells in the Presence of Aloe vera Extract. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue S1. 2021-10-08. PMID:33576207. |
mtt assay determined the ic50 value, and flow cytometry was employed to evaluate cell cycle distribution and apoptosis rates. |
2021-10-08 |
2023-08-13 |
Not clear |
| Yue He, Wenqiang Tao, Chao Shang, Chan Qi, Dexiang Ji, Wei Lu, Guoan Che. Xeroderma Pigmentosum group D suppresses proliferation and promotes apoptosis of HepG2 cells by downregulating ERG expression via the PPARγ pathway. International journal of experimental pathology. vol 102. issue 3. 2021-10-08. PMID:33993564. |
cell cycle and apoptosis were ascertained by flow cytometry, and cell viability was measured by mtt assay. |
2021-10-08 |
2023-08-13 |
human |
| Jian Zhang, Jie Xiang, Ting Liu, Xinwei Wang, Ying Tang, Yin Lian. miR-495 targets ROCK1 to inhibit lipopolysaccharides-induced WI-38 cells apoptosis and inflammation. The Kaohsiung journal of medical sciences. vol 36. issue 8. 2021-10-07. PMID:32237054. |
data from mtt (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) and flow cytometry assays showed that the decreased cell viability and induced cell apoptosis by lps treatment were also reversed by mir-495 over-expression. |
2021-10-07 |
2023-08-13 |
Not clear |
| Ying Xue, Ai-Zhong Wan. DJ-1 plays a neuroprotective role in SH-SY5Y cells by modulating Nrf2 signaling in response to lidocaine-mediated oxidative stress and apoptosis. The Kaohsiung journal of medical sciences. vol 36. issue 8. 2021-10-07. PMID:32363780. |
cell viability was measured by mtt assay, and apoptosis was measured by flow cytometry analysis. |
2021-10-07 |
2023-08-13 |
cat |
| Xinghai Chen, Debiao Son. LncRNA MEG3 Participates in Caerulein-Induced Inflammatory Injury in Human Pancreatic Cells via Regulating miR-195-5p/FGFR2 Axis and Inactivating NF-κB Pathway. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32856219. |
cell proliferation and apoptosis were detected by 3-(4, 5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay and flow cytometry assay, respectively. |
2021-10-07 |
2023-08-13 |
human |
| Bin Shan, Jia-Yan Li, Ya-Jiang Liu, Xiao-Bin Tang, Zheng Zhou, Liang-Xian Lu. LncRNA H19 Inhibits the Progression of Sepsis-Induced Myocardial Injury via Regulation of the miR-93-5p/SORBS2 Axis. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32996061. |
cell proliferation and apoptosis were detected by mtt assay and flow cytometry, respectively. |
2021-10-07 |
2023-08-13 |
human |
| Yujuan Qi, Kai Zhang, Peijun Li, Zhenhua W. Down-regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1. Inflammation. vol 44. issue 1. 2021-10-07. PMID:33064238. |
cell viability and apoptosis were respectively detected by mtt assay and flow cytometry. |
2021-10-07 |
2023-08-13 |
Not clear |
| Zhining Liu, Yimei Gu, Xiaohu Cheng, Heng Jiang, Yang Huang, Yingfeng Zhang, Gang Yu, Yunsheng Cheng, Lianbang Zho. Upregulation lnc-NEAT1 contributes to colorectal cancer progression through sponging miR-486-5p and activating NR4A1/Wnt/β-catenin pathway. Cancer biomarkers : section A of Disease markers. vol 30. issue 3. 2021-10-07. PMID:33337350. |
3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-2h-tetrazol-3-ium bromide (mtt) and flow cytometry assays were performed to evaluate proliferation and apoptosis of colorectal cancer cells, respectively. |
2021-10-07 |
2023-08-13 |
Not clear |
| Haider A Alkafaji, Ahmed Raji, Heshu S Rahman, Angelina O Zekiy, Ali Adili, Mohammadmahdi Jalili, Tahereh Hojjatipour, Angel Cid-Arregui, Navid Shomali, Saeed Tarzi, Rozita Tamjidifar, Ramin Heshmati, Faroogh Marofi, Morteza Akbari, Ali Hasanzadeh, Mina Deljavanghodrati, Mostafa Jarahian, Siamak Sandoghchian Shotorban. Up-regulation of KISS1 as a novel target of Let-7i in melanoma serves as a potential suppressor of migration and proliferation in vitro. Journal of cellular and molecular medicine. vol 25. issue 14. 2021-10-05. PMID:34096173. |
in the in vitro part of the study, let-7i mimics were transfected and the impact of its restoration on target gene expression, proliferation, migration and apoptosis of sk-mel-3 melanoma cell line was assessed by real-time pcr and western blotting, mtt assay, wound-healing assay and flow cytometry, respectively. |
2021-10-05 |
2023-08-13 |
Not clear |
| Hui Xiong, Jinsong Yu, Guangwei Jia, Yang Su, Jianliang Zhang, Qiu Xu, Xiaoxiong Su. Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells. Human cell. vol 34. issue 6. 2021-10-05. PMID:34346032. |
cell proliferation, apoptosis, and invasion were evaluated using mtt, flow cytometry analysis, and transwell invasion assay, respectively. |
2021-10-05 |
2023-08-13 |
Not clear |
| Wene Wei, Qijing Guo, Cuiping Guo, Xianshu Cui, Xuemei Ma, Xianliang Shen, Yushuang Lu. Ginsenoside Rh2 Suppresses Metastasis and Growth of Colon Cancer via miR-491. Journal of oncology. vol 2021. 2021-10-05. PMID:34603449. |
first, ginsenoside rh2 chitosan tripolyphosphate (cs-rh2-tpp) nanoparticles (nps) were constructed, and mtt, transwell, scratch adhesion, and flow cytometry assays were carried out for determining the impact of cs-rh2-tpp at various concentrations on growth, metastasis, and apoptosis of colon cancer cells (cccs). |
2021-10-05 |
2023-08-13 |
human |
| Renata Dobrucka, Aleksandra Romaniuk-Drapała, Mariusz Kaczmare. Biologically synthesized of Au/Pt/ZnO nanoparticles using Arctium lappa extract and cytotoxic activity against leukemia. Biomedical microdevices. vol 22. issue 4. 2021-10-04. PMID:33037930. |
this work also assessed the cytotoxicity of au/pt/zno nanoparticles by means of mtt assay, and analyzed apoptosis as well as the influence of the cultivation time and concentration of au/pt/zno nanoparticles on the percentage of dead cells. |
2021-10-04 |
2023-08-13 |
Not clear |
| Raja David Isac Evangeline Breeta, Viswanathan Mariammal Berlin Grace, Devarajan David Wilso. Methyl Palmitate-A suitable adjuvant for Sorafenib therapy to reduce in vivo toxicity and to enhance anti-cancer effects on hepatocellular carcinoma cells. Basic & clinical pharmacology & toxicology. vol 128. issue 3. 2021-10-04. PMID:33128309. |
the combination of sorafenib (4.5 µmol/l) with methyl palmitate (3 mmol/l) significantly enhanced anti-cancer effects on hep-g2 cell line by increasing cytotoxicity (p ≤ .05 in mtt assay; p ≤ .01 in trypan blue assay), apoptosis (p ≤ .05) and decreasing the metastatic migration (p ≤ .01) than sorafenib alone treatment. |
2021-10-04 |
2023-08-13 |
human |
| G Ávila, D De Leonardis, G Grilli, C Lecchi, F Cecilian. Anti-inflammatory activity of citrus pectin on chicken monocytes' immune response. Veterinary immunology and immunopathology. vol 237. 2021-10-04. PMID:34023617. |
the effects of different cp concentrations on cells' apoptosis and viability were assessed by measuring caspase-3 and -7 and the cells' metabolic activity (mtt assay), respectively. |
2021-10-04 |
2023-08-13 |
chicken |
| Ashraf Al Madhoun, Dania Haddad, Mustafa Al Tarrah, Sindhu Jacob, Waleed Al-Ali, Rasheeba Nizam, Lavina Miranda, Fatema Al-Rashed, Sardar Sindhu, Rasheed Ahmad, Milad S Bitar, Fahd Al-Mull. Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34088951. |
cell proliferation and apoptosis were evaluated by mtt assays and flow cytometry, gene expression was assessed by affymetrix microarray, signaling pathway perturbations were assessed in silico, and key regulatory proteins were validated by western blotting. |
2021-10-04 |
2023-08-13 |
Not clear |
| Hongyan Ma, Lu Ba. Effect of Polygonatum odoratum ethanol extract on high glucose-induced tubular epithelial cell apoptosis and oxidative stress. Pakistan journal of pharmaceutical sciences. vol 34. issue 3(Special). 2021-10-04. PMID:34602390. |
hk-2 cell activity and apoptosis were detected by mtt method and flow cytometry, respectively. |
2021-10-04 |
2023-08-13 |
Not clear |
| Yanlin Jin, Yi Zhang, Xiaoming Lu. circRNA_PTPRA functions as a sponge of miR-582-3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis. Experimental and therapeutic medicine. vol 22. issue 5. 2021-10-02. PMID:34594413. |
hcc cell viability, apoptosis, migration and invasion were measured using mtt, flow cytometry and transwell assays, respectively. |
2021-10-02 |
2023-08-13 |
human |