| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Huang, Gongzhi Wu, Chongxiong Peng, Xuyang Peng, Mingjiang Huang, Jianyang Ding, Huaizhong Zhang, Xuhui W. miR-126 regulates the proliferation, migration, invasion, and apoptosis of non-small lung cancer cells via AKT2/HK2 axis. IUBMB life. 2021-07-28. PMID:34320278. |
win vitro experiments including 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt), wound healing assay, transwell, and flow cytometry assay were used for evaluating the effect of mir-126 on cell proliferation, migration, invasion, and apoptosis. |
2021-07-28 |
2023-08-13 |
Not clear |
| Qiang Wang, Peigang Chu, Xia Yu, Jun Li, Wenzheng Zhang, Mingzhi Gon. ZFAS1 knockdown inhibits fibroblast-like synoviocyte proliferation, migration, invasion and inflammation, and promotes apoptosis via miR-3926/FSTL1 in rheumatoid arthritis. Experimental and therapeutic medicine. vol 22. issue 3. 2021-07-27. PMID:34306188. |
mtt assay, flow cytometric analysis and transwell assay were performed to examine the proliferation, apoptosis, migration and invasion of fibroblast-like synoviocytes (flss), respectively. |
2021-07-27 |
2023-08-13 |
human |
| Jin Zhang, Wei Hua, Xinyuan Zhao, Fan Yang, Ting Guo, Jianhua Zhang, Xuerong Zheng, Wanqi Lian. Paeoniflorin alleviates endothelial dysfunction caused by overexpression of soluble fms-like tyrosine kinase 1 and soluble endoglin in preeclampsia via VEGFA upregulation. Bioscience, biotechnology, and biochemistry. vol 85. issue 4. 2021-07-26. PMID:33590855. |
cell viability, migration, invasion, tube formation, and apoptosis were assessed by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium mtt assay, scratch assay, transwell assay, tube formation assay, and flow cytometry. |
2021-07-26 |
2023-08-13 |
human |
| Difang Chen, Kunwei Wang, Yan Zheng, Guangyu Wang, Mei Jian. Exosomes-Mediated LncRNA ZEB1-AS1 Facilitates Cell Injuries by miR-590-5p/ETS1 Axis Through the TGF-β/Smad Pathway in Oxidized Low-density Lipoprotein-induced Human Umbilical Vein Endothelial Cells. Journal of cardiovascular pharmacology. vol 77. issue 4. 2021-07-26. PMID:33818551. |
cell proliferation and apoptosis were assessed by mtt assay and flow cytometry analysis, respectively. |
2021-07-26 |
2023-08-13 |
human |
| Zhuangzhi Wu, Xiaoning He, Siqi Che. Oncogenic circDHTKD1 promotes tumor growth and metastasis of oral squamous cell carcinoma in vitro and in vivo via upregulating miR-326-mediated GAB1. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 54. issue 10. 2021-07-23. PMID:34287578. |
cellular behaviors were detected by 3-(4, 5-dimethylthiazol-2-y1)-2,5-diphenyl tetrazolium bromide (mtt) for cell viability, colony formation assay for clonal capacity, flow cytometry for cell apoptosis, wound healing assay for migration, and transwell assay for migration/invasion. |
2021-07-23 |
2023-08-13 |
mouse |
| Chen-Jun Zhang, Yu Huang, Ji-De Lu, Jie Lin, Zhi-Ru Ge, Hui Huan. Upregulated microRNA-132 rescues cardiac fibrosis and restores cardiocyte proliferation in dilated cardiomyopathy through the phosphatase and tensin homolog-mediated PI3K/Akt signal transduction pathway. Journal of cellular biochemistry. 2021-07-21. PMID:30216493. |
cell proliferation and apoptosis were tested by the mtt assay and flow cytometry. |
2021-07-21 |
2023-08-13 |
rat |
| Zun-Wen Lin, Wei Zhang, Si-Ding Jiang, Wen-Bo Wei, Xiao-Feng L. Inhibition of microRNA-940 suppresses the migration and invasion of human osteosarcoma cells through the secreted frizzled-related protein 1-mediated Wnt/β-catenin signaling pathway. Journal of cellular biochemistry. 2021-07-21. PMID:30324663. |
mtt (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay, scratch test, transwell assay, and flow cytometry were carried out to detect proliferation, migration, invasion, and apoptosis, respectively. |
2021-07-21 |
2023-08-13 |
mouse |
| Dan Wang, Suhong Zhang, Min Zhao, Fengling Che. LncRNA MALAT1 accelerates non-small cell lung cancer progression via regulating miR-185-5p/MDM4 axis. Cancer medicine. vol 9. issue 23. 2021-07-21. PMID:33146951. |
cell proliferation and apoptosis were, respectively, determined by 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt) assay, and flow cytometry. |
2021-07-21 |
2023-08-13 |
mouse |
| Jae Han Lee, So Hee Han, You Min Kim, Sung Hyun Kim, Eun Seon Yoo, Joong Seok Woo, Gi Hwan Jung, Soo Hyun Jung, Bum Seok Kim, Ji Youn Jun. Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis. Bioscience reports. vol 41. issue 1. 2021-07-21. PMID:33403388. |
we examined the anticancer effects of shikonin by in vitro experiments (mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, 4',6-diamidino-2-phenylindole (dapi) stain, annexin v/ propidium iodide (pi) stain, and protein analysis of apoptosis and mitogen-activated protein kinase (mapk) pathways). |
2021-07-21 |
2023-08-13 |
mouse |
| Xiao Chang, Yu-Ying Lin, Li-Na Bai, Wei Zh. miR-302a-3p suppresses melanoma cell progression via targeting METTL3. Journal of chemotherapy (Florence, Italy). 2021-07-21. PMID:34286671. |
the cell proliferation, cell cycle progression, apoptosis, colony formation, migration, and cell invasion ability were determined using mtt assay, propidium iodide (pi) staining, annexin v/pi flow cytometry, plate clone assay, and transwell migration and invasion assays, respectively. |
2021-07-21 |
2023-08-13 |
Not clear |
| Wangping Li, Chunmei Li, Lijie Ma, Faguang Ji. Resveratrol inhibits viability and induces apoptosis in the small‑cell lung cancer H446 cell line via the PI3K/Akt/c‑Myc pathway. Oncology reports. vol 44. issue 5. 2021-07-19. PMID:32901891. |
h446 cell viability and apoptosis were assessed with mtt and flow cytometry, and the expression of cytochrome c and the pi3k/akt/c‑myc pathway and the nuclear translocation of apoptosis inducing factor (aif) were assessed by western blotting. |
2021-07-19 |
2023-08-13 |
human |
| Hongyan Ma, Ying Liu, Zhengtian Li, Lu Yu, Yang Gao, Xiangmei Ye, Baoyi Yang, Hulun Li, Jinghui Sh. Propofol Protects Against Hepatic Ischemia Reperfusion Injury via Inhibiting Bnip3-Mediated Oxidative Stress. Inflammation. vol 44. issue 4. 2021-07-19. PMID:33496895. |
after the h/r liver cells were cultured and treated with pro, the viability, apoptosis, reactive oxygen species (ros) production, and the levels of lactate dehydrogenase (ldh), malondialdehyde (mda), tnf-α, and il-6 were detected by mtt, flow cytometry, colorimetry, and elisa. |
2021-07-19 |
2023-08-13 |
mouse |
| Dong-Ming Lai, Jiang-Jiang Bi, Yong-Hui Chen, Yu-Di Wu, Qing-Wen Huang, Hai-Jie Li, Sheng Zhang, Zheng Fu, Yi-Xin Ton. CCNI2 plays a promoting role in the progression of colorectal cancer. Cancer medicine. vol 10. issue 6. 2021-07-19. PMID:33620152. |
cell proliferation, colony formation, cell cycle, apoptosis, and mechanism investigation of ccni2 knockdown were investigated by mtt assay, colony formation assay, fluorescence-activated cell sorting, and human apoptosis antibody array, respectively. |
2021-07-19 |
2023-08-13 |
mouse |
| Qun Hang, Jie Lu, Lugen Zuo, Mulin Li. Linc00641 promotes the progression of gastric carcinoma by modulating the miR-429/Notch-1 axis. Aging. vol 13. issue 6. 2021-07-19. PMID:33714199. |
mtt assays, flow cytometry, wound healing assays, and transwell invasion assays were utilized to measure cell viability, apoptosis, migration and invasion, respectively. |
2021-07-19 |
2023-08-13 |
human |
| A Brito, T Santos, K Herculano, M Miranda, A K Sá, J L Carvalho, R Albertini, H Castro-Faria-Neto, A P Ligeiro-de-Oliveira, Flávio Aimbir. The MAPKinase Signaling and the Stimulatory Protein-1 (Sp1) Transcription Factor Are Involved in the Phototherapy Effect on Cytokines Secretion from Human Bronchial Epithelial Cells Stimulated with Cigarette Smoke Extract. Inflammation. vol 44. issue 4. 2021-07-19. PMID:33730343. |
human bronchial epithelial cell (beas) line was cultured in a medium with cse and irradiated (660 nm) at 9 j. apoptosis index was standardized with annexin v and the cellular viability was evaluated by mtt. |
2021-07-19 |
2023-08-13 |
human |
| Degui Shu, Yufen Xu, Wenyu Che. Knockdown of lncRNA BLACAT1 reverses the resistance of afatinib to non-small cell lung cancer via modulating STAT3 signalling. Journal of drug targeting. vol 28. issue 3. 2021-07-16. PMID:31359792. |
mtt assay, colony formation assay, apoptosis analysis, qrt-pcr and western blot analysis, immunohistochemistry, and in vivo study were carried out. |
2021-07-16 |
2023-08-13 |
Not clear |
| Yuanguo Xiong, Hao Lu, Hanlin X. Galangin Reverses Hepatic Fibrosis by Inducing HSCs Apoptosis via the PI3K/Akt, Bax/Bcl-2, and Wnt/β-Catenin Pathway in LX-2 Cells. Biological & pharmaceutical bulletin. vol 43. issue 11. 2021-07-16. PMID:32893252. |
cell viability was analyzed using cell counting kit-8 (cck-8) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, cell apoptosis was measured using flow cytometry, and the anti-fibrogenic effect of galangin was determined using rt-quantitative (q)pcr, immunofluorescence, and western blotting. |
2021-07-16 |
2023-08-13 |
Not clear |
| Wei-Ping Zheng, Fan-Long Meng, Lian-Yun Wan. miR-544a Stimulates endometrial carcinoma growth via targeted inhibition of reversion-inducing cysteine-rich protein with Kazal motifs. Molecular and cellular probes. vol 53. 2021-07-14. PMID:32525042. |
functionally, the mir-544a inhibitor restricted the proliferation [detected by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay], invasion, and migration (detected by transwell assay) of human endometrial adenocarcinoma cells (hec-1b and ishikawa) and facilitated cell apoptosis (detected by flow cytometry assay). |
2021-07-14 |
2023-08-13 |
mouse |
| Yameng Fan, Jiaqiao Li, Yuxuan Yang, Xiaodan Zhao, Yamei Liu, Yude Jiang, Long Zhou, Yang Feng, Yan Yu, Yilong Chen. Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation. International journal of oncology. vol 57. issue 4. 2021-07-14. PMID:32945383. |
cell viability was determined by mtt assay, and flow cytometry and tunel assay were used to evaluate cell apoptosis. |
2021-07-14 |
2023-08-13 |
human |
| Chi Pan, Huijie Duan, Yinan Wu, Chunpeng Zhu, Chenghao Yi, Yin Duan, Demin Lu, Cheng Guo, Deqi Wu, Yanyan Wang, Xianhua Fu, Jing Xu, Yiding Chen, Meng Luo, Wei Tian, Tao Pan, Wenhong Xu, Suzhan Zhang, Jianjin Huan. Inhibition of DNA‑PK by gefitinib causes synergism between gefitinib and cisplatin in NSCLC. International journal of oncology. vol 57. issue 4. 2021-07-14. PMID:32945394. |
mtt assay, apoptosis analysis, tumorsphere formation and an orthotropic xenograft mouse model were used to examine the combination effects of gefitinib and cisplatin on nsclc. |
2021-07-14 |
2023-08-13 |
mouse |