| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yongrui Liu, Ruiren Zhai, Siqin Hu, Jing Li. Circular RNA circ-RNF121 contributes to cisplatin (DDP) resistance of non-small-cell lung cancer cells by regulating the miR-646/SOX4 axis. Anti-cancer drugs. 2021-08-13. PMID:34387608. |
cell viability, proliferation, apoptosis, migration, invasion and cell cycle progression were assessed by 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt), colony formation, flow cytometry, wound-healing, transwell and flow cytometry assays, severally. |
2021-08-13 |
2023-08-13 |
Not clear |
| Nian Zhou, Bing Yan, Jing Ma, Hongchao Jiang, Li Li, Haoyu Tang, Fengming Ji, Zhigang Ya. Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis Molecular medicine reports. vol 24. issue 3. 2021-08-12. PMID:34278464. |
cell viability, cell cycle progression and cell apoptosis were assessed using the mtt assay and flow cytometry; the migration and invasion of kidney tumor cells were examined using transwell and wound‑healing assays; and the expression levels of wnt signaling pathway‑related genes (wnt1, β‑catenin and c‑myc) were detected by rt‑qpcr and western blotting. |
2021-08-12 |
2023-08-13 |
Not clear |
| Shokoufeh Yahyavy, Armita Valizadeh, Ghasem Saki, Layasadat Khorsand. Taurine ameliorates cytotoxic effects of Di(2-ethylhexyl) phthalate on Leydig cells. Andrologia. vol 53. issue 8. 2021-08-11. PMID:34165216. |
cell viability (mtt assay), apoptosis, oxidative stress and testosterone level were examined. |
2021-08-11 |
2023-08-13 |
Not clear |
| Zhi-Bin Jiang, Jie Gao, Yi-Hui Chai, Wen Li, Yun-Feng Luo, Yun-Zhi Che. Astragaloside alleviates alcoholic fatty liver disease by suppressing oxidative stress. The Kaohsiung journal of medical sciences. vol 37. issue 8. 2021-08-10. PMID:33973356. |
mtt and flow cytometry measured cell viability and apoptosis. |
2021-08-10 |
2023-08-13 |
rat |
| Jianyu Xu, Jianli Ma, Bixi Guan, Jian Li, Yan Wang, Songliu H. LncRNA HCP5 promotes malignant cell behaviors in esophageal squamous cell carcinoma via the PI3K/AKT/mTOR signaling. Cell cycle (Georgetown, Tex.). vol 20. issue 14. 2021-08-10. PMID:34190001. |
mtt assay, edu assay, tunel assay, transwell assay, and sphere formation assay were conducted to reveal escc cell viability, proliferation, apoptosis, migration, invasion, and stemness characteristics. |
2021-08-10 |
2023-08-13 |
Not clear |
| Shankargouda Patil, Hosam Ali Baeshe. Aqueous extract of tobacco induces mitochondrial potential dependent cell death and epithelial-mesenchymal transition in gingival epithelial cells. Saudi journal of biological sciences. vol 28. issue 8. 2021-08-07. PMID:34354447. |
after 48 h of incubation, mtt assay, annexin v/pi assay, and diic1(5) assay were used to evaluate viability, apoptosis, and mitochondrial potential of the cells. |
2021-08-07 |
2023-08-13 |
Not clear |
| Tong-Mei Zhang, Wen Wan. Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 7. 2021-08-06. PMID:33287919. |
cell proliferation was evaluated by an mtt assay, and the cell apoptosis was assessed by flow cytometry. |
2021-08-06 |
2023-08-13 |
Not clear |
| Weiguo Jin, Shichun Lu, Xiaolin Wang, Yusheng Shu, Hongcan Sh. Raddeanin A suppresses lung cancer cell proliferation via induction of apoptosis and increased production of ROS. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 7. 2021-08-06. PMID:33287938. |
cell proliferation and apoptosis were determined using mtt, and flow cytometric assays, respectively. |
2021-08-06 |
2023-08-13 |
human |
| Rong Ding, Wenyue Kang, Duozhi Wu, Lin Wan. Protective effect of propofol via the regulation of ovarian granulosa cell proliferation and apoptosis. Experimental and therapeutic medicine. vol 22. issue 3. 2021-08-06. PMID:34345270. |
human ovarian granulosa cell-like kgn cells, which were used as a representative of granulosa cells in the present study, were treated with different concentrations (0, 1, 5 and 10 µg/ml) of propofol for 48 h and cell proliferation and apoptosis were assessed using mtt and flow cytometry assays, respectively. |
2021-08-06 |
2023-08-13 |
human |
| Rong Ding, Wenyue Kang, Duozhi Wu, Lin Wan. Protective effect of propofol via the regulation of ovarian granulosa cell proliferation and apoptosis. Experimental and therapeutic medicine. vol 22. issue 3. 2021-08-06. PMID:34345270. |
kgn cells were transfected with mir-451a inhibitor or inhibitor control sequences for 6 h and treated with 10 µg/ml propofol for an additional 48 h. the results from the mtt, rt-qpcr and western blot assays indicated that 10 µg/ml propofol inhibited cell viability, induced apoptosis, enhanced cleaved caspase 3 expression, reduced pro-caspase 3 levels and inhibited the protein and mrna expression of wnt3a and β-catenin. |
2021-08-06 |
2023-08-13 |
human |
| Rongjun Gao, Hui Ye, Qingjun Gao, Nanpeng Wang, Yan Zhou, Haisong Dua. Inhibition of circular RNA_0000285 prevents cell proliferation and induces apoptosis in thyroid cancer by sponging microRNA-654-3p. Oncology letters. vol 22. issue 3. 2021-08-06. PMID:34345298. |
thyroid cancer cell viability and apoptosis were determined via the mtt assay and flow cytometric analysis, respectively, whereas the expression levels of circrna_0000285 and mir-654-3p were determined via reverse transcription-quantitative pcr analysis. |
2021-08-06 |
2023-08-13 |
Not clear |
| L I Dong, Yumin Zheng, Lianbo Gao, Xiaoguang Lu. lncRNA NEAT1 prompts autophagy and apoptosis in MPTP-induced Parkinson's disease by impairing miR-374c-5p. Acta biochimica et biophysica Sinica. vol 53. issue 7. 2021-08-05. PMID:33984130. |
the cellular viability and apoptosis of sh-sy5y were detected by mtt assay and flow cytometric analysis, respectively, and the number of autophagosomes was subsequently measured by transmission electron microscopy. |
2021-08-05 |
2023-08-13 |
mouse |
| Jing Zhao, Peifeng Li, Hua Zhu, Fengqin Ge, Jie Liu, Jingjun Xia, Pengzhou Han. 7,8-Dihydroxyflavone suppresses proliferation and induces apoptosis of human osteosarcoma cells. Acta biochimica et biophysica Sinica. vol 53. issue 7. 2021-08-05. PMID:34019097. |
human os cell lines (u2os and 143b) were treated with 7,8-dhf; cell viability and cell migration were assessed by methylthiazolyldiphenyl-tetrazolium bromide (mtt) assay and wound-healing assay, respectively; and cell death and apoptosis were evaluated by live/dead staining and terminal deoxynucleotidyl transferase (tdt) dutp nick-end labeling (tunel) assay, respectively. |
2021-08-05 |
2023-08-13 |
human |
| Jilong Hu, Zhinan Zheng, Jia Lei, Yuxin Cao, Qiyun Li, Zhi Zheng, Chuanjun Che. Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer. PPAR research. vol 2021. 2021-08-03. PMID:34335707. |
in vitro, pc cell lines panc-1 and aspc-1 were cultured, and mtt and flow cytometry were performed to observe the effects of pan-ppar agonist bezafibrate and ezh2 selective inhibitor gsk126 on cell viability and apoptosis. |
2021-08-03 |
2023-08-13 |
Not clear |
| Ji Li, Qing Xiang, Mei Wang, Hongchang Zhang, Rong Lian. All-Trans Retinoic Acid Enhances Chemosensitivity to 5-FU by Targeting miR-378c/E2F7 Axis in Colorectal Cancer. Journal of oncology. vol 2021. 2021-08-03. PMID:34335757. |
in this study, we utilized mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), transwell assay, and flow cytometry to confirm that atra was able to enhance the inhibitory effects of 5-fu on hct116 cells effectively by promoting cell apoptosis. |
2021-08-03 |
2023-08-13 |
Not clear |
| Ting-Yu Wu, Qin Leng, Li-Qun Tia. The microRNA-210/Casp8ap2 Axis Alleviates Hypoxia-Induced Myocardial Injury by Regulating Apoptosis and Autophagy. Cytogenetic and genome research. vol 161. issue 3-4. 2021-08-02. PMID:33882492. |
mtt was used to evaluate cell survival, and flow cytometry was used to assess apoptosis and the cell cycle distribution. |
2021-08-02 |
2023-08-13 |
Not clear |
| Ping Xiang, Youwen Sun, Zhiqing Fang, Keqiang Yan, Yidong Fa. Eukaryotic translation initiation factor 3 subunit b is a novel oncogenic factor in prostate cancer. Mammalian genome : official journal of the International Mammalian Genome Society. vol 31. issue 7-8. 2021-07-30. PMID:32556998. |
small interfering rna (sirna) knockdown of eif3b was introduced into prostate cancer cell line pc-3 and lncap, followed by examination of cell viability, proliferation and apoptosis using the mtt, cell counting and terminal deoxynucleotidyl transferase dutp nick end labeling assays, respectively. |
2021-07-30 |
2023-08-13 |
mouse |
| Juan He, Huaping Zhao, Xing Liu, Dongmei Wang, Yong Wang, Yanqiu Ai, Jianjun Yan. Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome‑mediated circ‑HMGCS1 via the miR‑34a‑5p/SGPP1 axis. Oncology reports. vol 44. issue 6. 2021-07-30. PMID:33125091. |
mtt assay, flow cytometric analysis and transwell assay were conducted to evaluate cell viability, apoptosis and invasion, respectively. |
2021-07-30 |
2023-08-13 |
human |
| Yalda Baghay Esfandyari, Mohammad Amin Doustvandi, Mohammad Amini, Behzad Baradaran, Sheyda Jodeiry Zaer, Nazila Mozammel, Mehdi Mohammadzadeh, Ahad Mokhtarzade. MicroRNA-143 Sensitizes Cervical Cancer Cells to Cisplatin: a Promising Anticancer Combination Therapy. Reproductive sciences (Thousand Oaks, Calif.). vol 28. issue 7. 2021-07-30. PMID:33569751. |
the cell viability and apoptosis induction were evaluated by mtt, annexin v-fitc/pi, and dapi staining tests. |
2021-07-30 |
2023-08-13 |
Not clear |
| Leila Soufi, Alireza Farasat, Hossein Ahmadpour-Yazdi, Leila Zolghadr, Nematollah Gheib. The effects of the esterified Quercetin with omega3 and omega6 fatty acids on viability, nanomechanical properties, and BAX/BCL-2 gene expression in MCF-7 cells. Molecular biology reports. vol 48. issue 6. 2021-07-29. PMID:34254227. |
using the mtt and flow cytometry assays, the cytotoxic potential, apoptosis, and necrosis were investigated. |
2021-07-29 |
2023-08-13 |
Not clear |