| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Yue, Zhilin Du, Jie Tao, Lei Sh. Inhibition of microRNA-297 alleviates THLE-2 cell injury induced by hypoxia/reoxygenation by inhibiting NLRP3 inflammasome activation via SIRT3. Canadian journal of physiology and pharmacology. 2021-09-24. PMID:34559973. |
after mir-297 antagomir and nlrp3 adenovirus vector delivery, thle-2 cell proliferation and apoptosis were measured by mtt, edu and tunel assays, respectively. |
2021-09-24 |
2023-08-13 |
Not clear |
| Yanhui Yu, Linjun Du, Jinxu Zhan. Febrile Seizure-Related miR-148a-3p Exerts Neuroprotection by Promoting the Proliferation of Hippocampal Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 43. issue 5. 2021-09-23. PMID:34348296. |
the effects of mir-148a-3p on hippocampal neuronal viability and apoptosis rate were detected by mtt and flow cytometry, respectively. |
2021-09-23 |
2023-08-13 |
Not clear |
| Tongyin Zhang, Botao Zhou, Junyi Sun, Jiangling Song, Limin Nie, Kairun Zh. Fraxetin suppresses reactive oxygen species-dependent autophagy by the PI3K/Akt pathway to inhibit isoflurane-induced neurotoxicity in hippocampal neuronal cells. Journal of applied toxicology : JAT. 2021-09-23. PMID:34553399. |
reactive oxygen species (ros) generation, cell viability, lactate dehydrogenase (ldh) release, and apoptosis were estimated by 2',7'-dichlorofluorescin-diacetate (dcfh-da) staining, mtt, ldh release, and terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling (tunel) staining assays, respectively. |
2021-09-23 |
2023-08-13 |
Not clear |
| Chuanguang Xiao, Xiaohong Wang, Jiacheng Shen, Yanjie Xia, Shusheng Qiu, Xiaodong Liang, Wenyue G. Luteolin-Loading Her-2 Nanospheres Enhances Targeting and Therapeutic Effects of Breast Cancer. Journal of biomedical nanotechnology. vol 17. issue 8. 2021-09-22. PMID:34544532. |
the proliferation and apoptosis of breast cancer cells were detected by mtt testing and flow cytometry examination, respectively. |
2021-09-22 |
2023-08-13 |
Not clear |
| Kuang Peng, Peiyong Jiang, Yafang Du, Dianmei Zeng, Junbi Zhao, Meiling Li, Chunchen Xia, Zhong Xie, Jie W. Oxidized low-density lipoprotein accelerates the injury of endothelial cells via circ-USP36/miR-98-5p/VCAM1 axis. IUBMB life. vol 73. issue 1. 2021-09-21. PMID:33249762. |
the viability, apoptosis and inflammation were detected by (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry and enzyme-linked immunosorbent assay (elisa), respectively. |
2021-09-21 |
2023-08-13 |
Not clear |
| Bingwu Liu, Xinfeng Yan, Zuojia Hou, Lei Zhang, Duwen Zhan. Impact of Bupivacaine on malignant proliferation, apoptosis and autophagy of human colorectal cancer SW480 cells through regulating NF-κB signaling path. Bioengineered. vol 12. issue 1. 2021-09-21. PMID:34151717. |
our work treated crc cells with bupivacaine, detected cell vitality through mtt assay, apoptosis through flow cytometry, cell migration through wound healing assay, nf-κb activity through immunofluorescence, inflammatory factor level, including tnf-α, il-1β as well as il-6 through eslia, apoptosis factor mrna expression, including bcl-2, bax and caspase-3q through qrt-pcr, and protein expression linking with nf-κb signaling pathway as well as autophagy-related proteins via western blot. |
2021-09-21 |
2023-08-13 |
human |
| Mohammadreza Azimi, Jalil Mehrzad, Armita Ahmadi, Elnaz Ahmadi, Ali Ghorbani Ranjbar. Apoptosis Induced by Ziziphora tenuior Essential Oil in Human Colorectal Cancer Cells. BioMed research international. vol 2021. 2021-09-21. PMID:34337019. |
after mtt assay and determination of the percentage of apoptosis by flow cytometry, rna extraction was performed and the expression levels of bax, bcl-2, caspase 3 (c3), and caspase 9 (c9) were analyzed using newly designed primers by reverse transcription (rt) qpcr method and genix6 software. |
2021-09-21 |
2023-08-13 |
human |
| Lifeng Chen, Qiping Lu, Jianhua Chen, Ruibing Feng, Chenxi Yan. Upregulating miR-27a-3p inhibits cell proliferation and inflammation of rheumatoid arthritis synovial fibroblasts through targeting toll-like receptor 5. Experimental and therapeutic medicine. vol 22. issue 5. 2021-09-21. PMID:34539823. |
cell proliferation, apoptosis and inflammatory response were measured with mtt assay, flow cytometry and elisa kits, respectively. |
2021-09-21 |
2023-08-13 |
Not clear |
| Lixia Feng, Xu Chen, Shenghua Zhang, Yunxia Chen, Yanling Y. Role of miR-139-5p in ectopic endometrial stromal cells and the underlying molecular mechanism. Experimental and therapeutic medicine. vol 22. issue 5. 2021-09-21. PMID:34539847. |
flow cytometry analysis, and mtt and transwell assays were performed to assess cell apoptosis, viability, and migration and invasion of the cells transfected with inhibitor control, mir-139-5p inhibitor, mir-139-5p inhibitor + control-small interfering (si)rna or mir-139-5p inhibitor + bbc3-sirna, respectively. |
2021-09-21 |
2023-08-13 |
Not clear |
| Kyunghyun Yoo, Hye-Hyeon Yun, Soon-Young Jung, Jeong-Hwa Le. KRIBB11 Induces Apoptosis in A172 Glioblastoma Cells via MULE-Dependent Degradation of MCL-1. Molecules (Basel, Switzerland). vol 26. issue 14. 2021-09-20. PMID:34299435. |
using mtt and colony formation assays and western blotting for c-parp, we demonstrated that kribb11 substantially inhibits the growth of a172 glioma cells by inducing apoptosis. |
2021-09-20 |
2023-08-13 |
Not clear |
| Jingyun Zhang, Liu Yang, Xiaoxiao Han, Chenchi Li, Ranyang Liu, Zihua Ma, Bing Han, Rujia Xie, Qin Yan. [Endoplasmic reticulum stress in hepatic stellate cells induced by tunicamycin promotes apoptosis and cell cycle arrest]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 37. issue 9. 2021-09-20. PMID:34533126. |
hsc-t6 cells were randomized into control group, treatment group with 1 ml/l of dimethyl sulfoxide (dmso), and treatment group with 1 μg/ml of tunicamycin, and the cells were treated for 12 h. mtt assay was used to detect cell proliferation, flow cytometry to detect apoptosis and cell cycle, and western blot to detect the protein expressions of α-smooth muscle actin (α-sma), c/ebp camp homologous protein (chop), caspase-12, and cyclin d1. |
2021-09-20 |
2023-08-13 |
rat |
| Feng Gao, Shihai Yan, Zheng Sun, Jia Wan. Muscone suppresses gastric cancer via regulation of miRNA-145. Food science & nutrition. vol 9. issue 9. 2021-09-18. PMID:34531985. |
an optimal muscone concentration was determined using mtt and cell apoptosis tests. |
2021-09-18 |
2023-08-13 |
Not clear |
| Feng Gao, Shihai Yan, Zheng Sun, Jia Wan. Muscone suppresses gastric cancer via regulation of miRNA-145. Food science & nutrition. vol 9. issue 9. 2021-09-18. PMID:34531985. |
cell proliferation rate, apoptosis rate, cell cycle phase distribution, number of invading cells, and wound healing rate were compared among the five groups using mtt, flow cytometry, transwell, and wound healing assays. |
2021-09-18 |
2023-08-13 |
Not clear |
| Shubin Song, Xuezhi He, Jing Wang, Hongtao Song, Yimin Wang, Yansong Liu, Zhengbo Zhou, Zhiyong Yu, Dengshun Miao, Yingwei Xu. A novel long noncoding RNA, TMEM92-AS1, promotes gastric cancer progression by binding to YBX1 to mediate CCL5. Molecular oncology. vol 15. issue 4. 2021-09-17. PMID:33247987. |
mtt, colony-formation assays, edu, cell cycle, apoptosis and subcutaneous tumour formation assays were used to detect the role of tmem92-as1 in cell function. |
2021-09-17 |
2023-08-13 |
Not clear |
| Yuan Wang, Huazhang Wu, Nannan Dong, Xu Su, Mingxiu Duan, Yaqin Wei, Jun Wei, Gaofeng Liu, Qingjie Peng, Yunli Zha. Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells. Scientific reports. vol 11. issue 1. 2021-09-17. PMID:33510228. |
in the present study, we investigate the effects of sfn on cell proliferation, cell cycle, cell apoptosis, and also the expression of several cell cycle and apoptosis-related genes by mtt assay, flow cytometry and western blot analysis in gastric cancer (gc) cells. |
2021-09-17 |
2023-08-13 |
Not clear |
| Ling Kong, Rebekah Karns, Mohamed Tarek M Shata, Jennifer L Brown, Michael S Lyons, Kenneth E Sherman, Jason T Blackar. The synthetic opioid fentanyl enhances viral replication in vitro. PloS one. vol 16. issue 4. 2021-09-17. PMID:33852610. |
viral protein synthesis was quantified by elisa, while apoptosis and cell death were measured by m30 or mtt assays, respectively. |
2021-09-17 |
2023-08-13 |
Not clear |
| Negin Nokhandani, Mahdieh Naghavi Alhosseini, Ali Memarian, Homa Davood. Combination of 5-fluorouracil and Lipopolysaccharide Synergistically Induces Cytotoxicity and Apoptosis in MCF-7 Human Breast Cancer Cells. Iranian journal of allergy, asthma, and immunology. vol 19. issue 4. 2021-09-16. PMID:33463109. |
the effects of lps and 5-fu on cytotoxicity, apoptosis, and gene expression in nf-κb, erk, and akt signaling pathways were evaluated by mtt assay, annexin v/propidium iodide (pi) apoptosis assay, and qrt-pcr, respectively. |
2021-09-16 |
2023-08-13 |
human |
| Shuo Wu, Yao Zhang, Yan Zhang, Lizhan Chen, Xi Xu, Yinli Dang, Xinyu T. Phillygenin regulates proliferation and apoptosis of non-small cell lung cancer through by AMPK/ERK/NF-κB axis. Die Pharmazie. vol 75. issue 10. 2021-09-14. PMID:33305728. |
in this study, mtt assay and flow cytometry were conducted to investigate the effect of pg on proliferation and apoptosis of nsclc cells |
2021-09-14 |
2023-08-13 |
Not clear |
| Renjie Dou, Jinjun Qian, Wei Wu, Yanxin Zhang, Yuxia Yuan, Mengjie Guo, Rongfang Wei, Shu Yang, Artur Jurczyszyn, Siegfried Janz, Meral Beksac, Chunyan Gu, Ye Yan. Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. Cell death & disease. vol 12. issue 2. 2021-09-14. PMID:33627630. |
mtt and flow cytometry were used to assess mm cell proliferation, cell cycle, and apoptosis post inducible knockdown srd5a1 by lentivirus-mediated short-hairpin rna (shrna). |
2021-09-14 |
2023-08-13 |
mouse |
| Ling Yang, Lijuan Wang, Juan Wang, Ping Li. Long non-coding RNA Gm11974 aggravates oxygen-glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke. Metabolic brain disease. vol 36. issue 7. 2021-09-14. PMID:34338972. |
cell viability and apoptosis were determined by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay, caspase-3 assay kit and flow cytometry. |
2021-09-14 |
2023-08-13 |
mouse |