| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nur Şebnem Ersöz, Aysun Ada. Resveratrol triggers anti-proliferative and apoptotic effects in FLT3-ITD-positive acute myeloid leukemia cells via inhibiting ceramide catabolism enzymes. Medical oncology (Northwood, London, England). vol 39. issue 3. 2022-01-21. PMID:35059910. |
resveratrol, ski ii (sk inhibitor) and pdmp (gcs inhibitor) were evaluated alone or in combinations for their effect on cell proliferation (mtt assay), apoptosis (annexin v-fitc/pi staining by flow cytometry) and cell cycle progression (pi staining by flow cytometry) in molm-13 and mv4-11 cells. |
2022-01-21 |
2023-08-13 |
Not clear |
| Zhiqin Ye, Lu Wei, Xietian Yin, Huiling Li, Guifu Qin, Siqi Li, Tingting Peng, Bo Liu, Shichao Zhao, Qin Zhu. Long non-coding RNA cancer susceptibility candidate 2 regulates the function of human fibroblast-like synoviocytes via the microRNA-18a-5p/B-cell translocation gene 3 signaling axis in rheumatoid arthritis. Bioengineered. vol 13. issue 2. 2022-01-20. PMID:35045800. |
overexpression of lncrna casc2 decreased the viability of human fibroblast-like synoviocytes (hflss) and induced apoptosis, as revealed by the mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and flow cytometry analyses. |
2022-01-20 |
2023-08-13 |
human |
| Xin Wu, Ling Qiu, Hao Feng, Hao Zhang, Hailin Yu, Yan Du, Hao Wu, Shurong Zhu, Yuanyuan Ruan, Hua Jian. KHDRBS3 promotes paclitaxel resistance and induces glycolysis through modulated MIR17HG/CLDN6 signaling in epithelial ovarian cancer. Life sciences. 2022-01-20. PMID:35051418. |
the biological functions of khdrbs3, mir17hg and cldn6 were examined using mtt, colony formation, apoptosis and seahorse assays in vitro. |
2022-01-20 |
2023-08-13 |
Not clear |
| Fatemeh Emamdoust, Mehdi Aminafshar, Mohammad Zandi, Mohammad Reza Sanjab. The role of Rho-associated kinase inhibitor, Y-27632 on primary culture of ovine spermatogonial stem cells. Animal reproduction. vol 18. issue 4. 2022-01-17. PMID:35035539. |
the viability of sscs, the apoptosis assay of sscs, the intracellular reactive oxygen species (ros) analysis, and the sscs markers and apoptosis-related gene expressions were detected by mtt reduction assay, annexin v-fitc/ propidium iodide (pi) dual staining, flow cytometry and real-time-pcr studies, respectively. |
2022-01-17 |
2023-08-13 |
Not clear |
| Yuebin Wang, Huike Yang, Xian Su, Anqiang Cao, Feng Chen, Peng Chen, Fangtao Yan, Huirong H. SREBP2 promotes the viability, proliferation, and migration and inhibits apoptosis in TGF-β1-induced airway smooth muscle cells by regulating TLR2/NF-κB/NFATc1/ABCA1 regulatory network. Bioengineered. vol 13. issue 2. 2022-01-17. PMID:35037821. |
cell viability, proliferation, apoptosis, migration, and the expression of srebp2, abca1 and related pathway proteins were detected by mtt assay, brdu staining, flow cytometer, transwell assay, qrt-pcr, and western blotting, respectively. |
2022-01-17 |
2023-08-13 |
Not clear |
| Yixia Zhang, Xindan Meng, Keyu Li. The modulation of cAMP/PKA pathway by asiaticoside ameliorates high glucose-induced inflammation and apoptosis of retinal pigment epithelial cells. Journal of bioenergetics and biomembranes. 2022-01-17. PMID:35038080. |
then, cell survival rate, expression of inflammatory factors, oxidative stress, and apoptosis were measured by mtt method, western blot, oxidative stress detection kits and tunel respectively. |
2022-01-17 |
2023-08-13 |
human |
| Rajendran Amarnath Praphakar, Rajadas Sam Ebenezer, Sounderrajan Vignesh, Harshavardhan Shakila, Mariappan Raja. Versatile pH-Responsive Chitosan-g-Polycaprolactone/Maleic Anhydride-Isoniazid Polymeric Micelle To Improve the Bioavailability of Tuberculosis Multidrugs. ACS applied bio materials. vol 2. issue 5. 2022-01-15. PMID:35030682. |
the nontoxic nature of the micelles was assessed by ex vivo studies on u937 and l929 cell lines and erythrocytes by performing an mtt assay, apoptosis assay, and hemolysis assay. |
2022-01-15 |
2023-08-13 |
zebrafish |
| Mingjia Gu, Fang Yin, Yuening Qin, Yali Tian, Xinjie Xiu, Hanjing Shen, Jiebin Zh. Synergistic antitumor efficacy of PD-1-conjugated PTX- and ZSQ-loaded nanoliposomes against multidrug-resistant liver cancers. Drug delivery and translational research. 2022-01-15. PMID:35031972. |
terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) staining and reactive oxygen species (ros) analysis demonstrated that pd-pzlp triggered an excessive ros reaction and cell apoptosis compared with that of free ptx or zsq, which was also consistent with the cell antiproliferative effects in mtt assay. |
2022-01-15 |
2023-08-13 |
human |
| Mallikarjun Gundappa, Vijaya Anand Arumugam, Hsi-Lung Hsieh, Balamuralikrishnan Balasubramanian, Velayuthaprabhu Shanmuga. Expression of tissue factor and TF-mediated integrin regulation in HTR-8/SVneo trophoblast cells. Journal of reproductive immunology. vol 150. 2022-01-14. PMID:35030354. |
in addition, cell migration assays, mtt, and dapi were performed to examine migration, cytotoxicity and apoptosis effect of fviia. |
2022-01-14 |
2023-08-13 |
Not clear |
| Lekshmi Krishna, Sagar Nilawar, Murugeswari Ponnalagu, Murali Subramani, Chaitra Jayadev, Rohit Shetty, Kaushik Chatterjee, Debashish Da. Fiber Diameter Differentially Regulates Function of Retinal Pigment and Corneal Epithelial Cells on Nanofibrous Tissue Scaffolds. ACS applied bio materials. vol 3. issue 2. 2022-01-12. PMID:35019286. |
the molecular changes in the cells in response to the different fibers were analyzed by qrt-pcr, western blot, immunofluorescence, elisa, flow cytometry, mtt assay, and sem to assess properties such as proliferation, apoptosis, membrane potential, epithelial-mesenchymal transition, stem cell population, vegf-a secretion, differentiation, and metabolic status of the cells. |
2022-01-12 |
2023-08-13 |
human |
| Dong Zhao, Yueting Ho. Long non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) upregulates Cyclin T2 (CCNT2) in laryngeal papilloma through sponging miR-577/miR-1224-5p and blocking cell apoptosis. Bioengineered. vol 13. issue 1. 2022-01-11. PMID:35012431. |
q-pcr, mtt, edu and western blotting were performed to determine that lnc-neat1 facilitates lp cell proliferation and hinders cell apoptosis. |
2022-01-11 |
2023-08-13 |
Not clear |
| Dong Zhao, Yueting Ho. Long non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) upregulates Cyclin T2 (CCNT2) in laryngeal papilloma through sponging miR-577/miR-1224-5p and blocking cell apoptosis. Bioengineered. vol 13. issue 1. 2022-01-11. PMID:35012431. |
western blotting, mtt and edu were used to confirm that lnc-neat1 promoted lp cell proliferation and inhibited cell apoptosis through ccnt2. |
2022-01-11 |
2023-08-13 |
Not clear |
| Gang Wang, Yanan Wang, Qinzhi Yang, Chunrong Xu, Youkun Zheng, Liqun Wang, Jianbo Wu, Min Zeng, Mao Lu. Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo. Cell death & disease. vol 13. issue 1. 2022-01-11. PMID:35013107. |
cell viability and apoptosis were assessed by the mtt assay, tunel staining, and annexin v-fitc and propidium iodide double staining. |
2022-01-11 |
2023-08-13 |
Not clear |
| Peng Wang, Yuanjing Hu, Pengpeng Qu, Ying Zhao, Jing Liu, Jianguo Zhao, Beihua Kon. Protein tyrosine phosphatase receptor type Z1 inhibits the cisplatin resistance of ovarian cancer by regulating PI3K/AKT/mTOR signal pathway. Bioengineered. vol 13. issue 1. 2022-01-10. PMID:35001804. |
mtt experiment and flow cytometer indicated that overexpression of ptprz1 enhanced the ddp sensitivity of oc cells and promoted the cell apoptosis. |
2022-01-10 |
2023-08-13 |
Not clear |
| Nadeeya Mad-Adam, Thidarath Rattanaburee, Tanotnon Tanawattanasuntorn, Potchanapond Graidis. Effects of trans-(±)-kusunokinin on chemosensitive and chemoresistant ovarian cancer cells. Oncology letters. vol 23. issue 2. 2022-01-07. PMID:34992691. |
mtt, colony formation, apoptosis and multi-caspase assays were used to determine cytotoxicity, the ability of single cells to form colonies, induction of apoptosis and multi-caspase activity, respectively. |
2022-01-07 |
2023-08-13 |
Not clear |
| Xin-Yu Lu, Zhong-Ze Wang, Si-Cheng Wan, Er-Hu Zhao, Hong-Juan Cu. [Effects of tetrandrine on proliferation, migration, and invasion of glioblastoma cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994145. |
in this study, mtt and brdu assays were employed to detect the effect of tet on the proliferation of ln229 glioblastoma cells; flow cytometry was used to analyze the cycle distribution and apoptosis; plate cloning assay and soft agar colony formation assay were performed to study the colony formation ability of ln229 cells exposed to tet; scratch assay and transwell assay were conducted to detect the ability of migration and invasion; western blot was adopted to the exploration of the molecular mechanism. |
2022-01-07 |
2023-08-13 |
Not clear |
| Jikun Du, Daibo Song, Yuanhua Li, Jierong Liu, Xiaoman Huang, Baohong Li, Li L. Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K. Neurotoxicity research. 2022-01-07. PMID:34994954. |
saikosaponin-d pretreatment could ameliorate glutamate-induced cytotoxicity according to mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and depress apoptosis according to hoechst 33,342 staining and annexin v-fitc/pi double staining in sh-sy5y cells. |
2022-01-07 |
2023-08-13 |
Not clear |
| Shu-Ling Hsieh, Jia-Huei Li, Cheng-Di Dong, Chiu-Wen Chen, Chih-Chung W. Carnosine suppresses human colorectal cancer cell proliferation by inducing necroptosis and autophagy and reducing angiogenesis. Oncology letters. vol 23. issue 2. 2022-01-03. PMID:34976156. |
after human colorectal cancer hct-116 cells were treated carnosine for 72 or 96 h, the cell proliferation, apoptosis, autophagy, necroptosis, angiogenesis and the expression of related regulatory molecules were detected using mtt assays, fluorescence image analysis and rt-qpcr in this study. |
2022-01-03 |
2023-08-13 |
human |
| Yulong Wang, Shuiting Zhai, Jianwu Xing, Yingkun He, Tianxiao L. LncRNA GAS5 promotes abdominal aortic aneurysm formation through regulating the miR-185-5p/ADCY7 axis. Anti-cancer drugs. 2022-01-02. PMID:34974476. |
cell viability was detected by mtt assay, and cell apoptosis was assessed by flow cytometry. |
2022-01-02 |
2023-08-13 |
human |
| Jitender K Bhardwaj, Vijay Kumar, Priyanka Saraf, Harish Panchal, Vishavjeet Rathee, Som N Sachdev. Efficacy of N-acetyl- l-cysteine against glyphosate induced oxidative stress and apoptosis in testicular germ cells preventing infertility. Journal of biochemical and molecular toxicology. 2021-12-29. PMID:34964212. |
gly also decreased the cell viability and increased the incidence of apoptosis in testicular cells in a dose- and time-dependent manner as revealed by mtt assay and fluorescence (ethidium bromide/acridine orange) assay, respectively. |
2021-12-29 |
2023-08-13 |
cat |