| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sisi Zhang, Yingping Xu, Qingyu Zhen. circRNA_0000285 knockdown suppresses viability and promotes apoptosis of cervical cancer cells by sponging microRNA-654-3p. Bioengineered. vol 13. issue 3. 2022-02-15. PMID:35166172. |
in addition, the effect of circrna_0000285 inhibition on cell viability, apoptosis, and the expression of apoptosis-related markers was assessed using mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), flow cytometry, and western blotting assays, respectively. |
2022-02-15 |
2023-08-13 |
Not clear |
| Huan Wu, Hui Cheng, Shengyong Luo, Can Peng, An Zhou, Zhiwu Chen, Hong Wu, Qinglin L. Use of cellular metabolomics and lipidomics to decipher the mechanism of Huachansu injection-based intervention against human hepatocellular carcinoma cells. Journal of pharmaceutical and biomedical analysis. vol 212. 2022-02-14. PMID:35158184. |
mtt and dapi staining were performed to evaluate the effects of hcs injection on cell proliferation and apoptosis, respectively, in human hepg2 hcc cells with and without hcs treatment. |
2022-02-14 |
2023-08-13 |
mouse |
| T Tuerxun, X Li, F Lou, X Wang, L M. YBX1 Protects against Apoptosis Induced by Oxygen-Glucose Deprivation/Reoxygenation in PC12 Cells via Activation of the AKT/GSK3β Pathway. Folia biologica. vol 67. issue 4. 2022-02-12. PMID:35151240. |
next, the effect of ybx1 on the apoptosis and viability of ogd/r-treated pc12 cells was evaluated by flow cytometry, mtt assay, and western blot. |
2022-02-12 |
2023-08-13 |
cat |
| Yang Yu, Tingting Yang, Zhaozheng Ding, Yuan Ca. Circ_0026579 alleviates LPS-induced WI-38 cells inflammation injury in infantile pneumonia. Innate immunity. vol 28. issue 1. 2022-02-10. PMID:35142578. |
cell proliferation and apoptosis were measured by mtt assay, edu staining and flow cytometry. |
2022-02-10 |
2023-08-13 |
Not clear |
| Mansoureh Hashemi, Aida Abbasiazam, Saeed Oraee-Yazdani, Janice Lenze. Response of human glioblastoma cells to hyperthermia: Cellular apoptosis and molecular events. Tissue & cell. vol 75. 2022-02-10. PMID:35144007. |
cell survival rate by mtt assay and apoptosis using quantitative real-time rt-pcr and western blot were evaluated. |
2022-02-10 |
2023-08-13 |
human |
| Cheng Xue, Rong Wang, Yu Ji. Downregulation of miR-23a-3p improves cognitive function in rats after subarachnoid hemorrhage by targeting VCAN. Medical molecular morphology. 2022-02-09. PMID:35137264. |
the viability and apoptosis of bmecs were evaluated using mtt, flow cytometry, and western blotting analyses. |
2022-02-09 |
2023-08-13 |
rat |
| Demeng Yang, Xinyuan Hu, Yuan Chen, Changgeng Wan. Circular RNA Derived from Vacuolar ATPase Assembly Factor VMA21 Suppresses Lipopolysaccharide-Induced Apoptosis of Chondrocytes in Osteoarthritis (OA) by Decreasing Mature miR-103 Production. Molecular biotechnology. 2022-02-09. PMID:35138580. |
the involvement of vma21 and mir-103 in lipopolysaccharide (lps)-induced chondrocyte apoptosis and viability was analyzed using cell apoptosis assay and 2,5-diphenyl-2h-tetrazolium bromide (mtt) assay, respectively. |
2022-02-09 |
2023-08-13 |
Not clear |
| Chaohui Liu, Jiansheng Pan, Hongyu Liu, Rongkai Lin, Yijie Chen, Chenghua Zhan. Daphnetin inhibits the survival of hepatocellular carcinoma cells through regulating Wnt/β-catenin signaling pathway. Drug development research. 2022-02-08. PMID:35132666. |
mtt （3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide）, colony formation, flow cytometry, and tumor-bearing experiments were applied to evaluate the effects of different concentrations of daphnetin on cell viability, apoptosis, cell cycle, and in vivo tumor formation, respectively. |
2022-02-08 |
2023-08-13 |
human |
| Chan Yu, Linghui Zhan. Methylprednisolone up-regulates annexin A1 (ANXA1) to inhibit the inflammation, apoptosis and oxidative stress of cigarette smoke extract (CSE)-induced bronchial epithelial cells, a chronic obstructive pulmonary disease in vitro model, through the formyl peptide receptor 2 (FPR2) receptors and the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) pathway. Bioengineered. vol 13. issue 2. 2022-02-07. PMID:35129068. |
with the help of mtt and tunel assays, the viability and apoptosis of beas-2b cells after indicated treatment were assessed. |
2022-02-07 |
2023-08-13 |
human |
| Vahid Asghariazar, Mahtab Kadkhodayi, Behzad Mansoori, Ali Mohammadi, Behzad Baradara. Restoration of miR-143 reduces migration and proliferation of bladder cancer cells by regulating signaling pathways involved in EMT. Molecular and cellular probes. 2022-02-05. PMID:35121085. |
the influence of mir-143 overexpression on bc cells migration, proliferation, and apoptosis was detected using wound-healing assay, mtt assay, and dapi and annexin v/pi staining, respectively. |
2022-02-05 |
2023-08-13 |
Not clear |
| Hao Zha, Wei Miao, Wei Rong, Aimei Wang, Weiqi Jiang, Rui Liu, Lanqi Liu, Ying Wan. Remote ischaemic perconditioning reduces the infarct volume and improves the neurological function of acute ischaemic stroke partially through the miR-153-5p/TLR4/p65/IkBa signalling pathway. Folia neuropathologica. vol 59. issue 4. 2022-02-04. PMID:35114774. |
overexpressed or silenced mir-153-5p was transfected into the cells to analyse the effects of oxygen-glucose deprivation (ogd) treatment on neuro-2a cell viability, apoptosis, and related gene expressions by performing quantitative real-time polymerase chain reaction (qrt-pcr), mtt assay, flow cytometry, and western blot. |
2022-02-04 |
2023-08-13 |
mouse |
| Xiaoling Zhang, Si Wang, Yuyan Cai, Weihong He, Qing Yang, Chen L. Regulatory Mechanism of MicroRNA-9 / Long Non-Coding RNA XIST Expression on Mouse Macrophage RAW264.7 Apoptosis Induced by Oxidized Low Density Lipoprotein. Bioengineered. vol 13. issue 2. 2022-02-03. PMID:35109760. |
methylthiazolyl tetrazolium (mtt) method, flow cytometry, and western blot were used to detect and compare the differences of cell proliferation, apoptosis, and the expression levels of apoptosis signal-regulating kinase 1 (ask1), c-jun n-terminal kinase (jnk), matrix metalloproteinase-9 (mmp-9), and b-cell lymphoma-2 (bcl-2) after ox-ldl induction and transfection of mir-9 mimic, mir-9 inhibitor and xist expression vector, respectively. |
2022-02-03 |
2023-08-13 |
mouse |
| Meltem Akbaba, Gökhan Gurur Gökmen, Duygu Kışla, Ayşe Nalbantso. In Vivo Investigation of Supportive Immunotherapeutic Combination of Bifidobacterium infantis 35624 and Doxorubicin in Murine Breast Cancer. Probiotics and antimicrobial proteins. 2022-02-03. PMID:35112297. |
the mtt assay was used to determine the cytotoxicity of doxorubicin against cancer cells, and apoptosis was analyzed by using flow cytometry. |
2022-02-03 |
2023-08-13 |
Not clear |
| Vanuchawan Wisuitiprot, Kornkanok Ingkaninan, Panlop Chakkavittumrong, Wudtichai Wisuitiprot, Nitra Neungchamnong, Ruttanaporn Chantakul, Neti Waranuc. Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage. Scientific reports. vol 12. issue 1. 2022-01-28. PMID:35087085. |
the preventive effect on dermal papilla cell apoptosis induced by testosterone was determined by mtt assay. |
2022-01-28 |
2023-08-13 |
human |
| Jun Peng, Zheng-Tao Yu, Rong-Jun Xiao, Qing-Song Wang, Ying Xi. LncRNA CEBPA-AS1 knockdown prevents neuronal apoptosis against oxygen glucose deprivation/reoxygenation by regulating the miR-455/GPER1 axis. Metabolic brain disease. 2022-01-28. PMID:35088289. |
neuronal viability and apoptosis were examined using mtt and flow cytometry assays, followed by determination of apoptosis-related factors (caspase 3, caspase 8, caspase 9, bax, and bcl-2). |
2022-01-28 |
2023-08-13 |
Not clear |
| Xiaoxiao Tao, Yaping Jiang, Xian Zheng, Xiaoxiao Ji, Feifei Pen. Dihydromyricetin ameliorates oxygen‑glucose deprivation and re‑oxygenation‑induced injury in HT22 cells by activating the Wnt/β‑catenin signaling pathway. Molecular medicine reports. vol 25. issue 3. 2022-01-28. PMID:35088876. |
the effects of dmy on the viability, oxidative stress and apoptosis of ht22 cells following oxygen‑glucose deprivation and re‑oxygenation (ogd/r) were examined using mtt, lactate dehydrogenase (ldh), superoxide (sod), malondialdehyde (mda), western blot and tunel assays. |
2022-01-28 |
2023-08-13 |
Not clear |
| Zhong Lv, Guanhao Xie, Haowen Cui, Zhi Yao, Congxiang Shao, Weiquan Yuan, Bailing Che. Cyclosporin-A reduced the cytotoxicity of propranolol in HUVECs via p38 MAPK signaling. Medicine. vol 101. issue 4. 2022-01-28. PMID:35089188. |
at 24 hours after treatment, the levels of reactive oxygen species (ros), cell proliferation, and apoptosis were determined using the ros kit, mtt assay, and annexin v staining. |
2022-01-28 |
2023-08-13 |
human |
| Xiaodong Yu, Tao Wu, Bo Liao, Zhongbo Du, Pingyu Zh. Anticancer potential of corilagin on T24 and TSGH 8301 bladder cancer cells via the activation of apoptosis by the suppression of NF-κB-induced P13K/Akt signaling pathway. Environmental toxicology. 2022-01-27. PMID:35084093. |
the cytotoxicity, apoptosis, adhesion, and migration of clg on bc cells t24 and tsgh 8301 were evaluated by mtt assay, dapi, rh-123, cell adhesion, and cell migration assay. |
2022-01-27 |
2023-08-13 |
Not clear |
| Zidan Zhao, Junjian He, Chao Fen. CircCBFB is a mediator of hepatocellular carcinoma cell autophagy and proliferation through miR-424-5p/ATG14 axis. Immunologic research. 2022-01-23. PMID:35066780. |
after transfection with pcdna3.1-circcbfb, sh-circcbfb, mir-424-5p mimic, mir-424-5p inhibitor, pcdna3.1-atg14, sh-atg14, sh-circcbfb + mir-424-5p inhibitor, pcdna3.1-circcbfb + mir-424-5p mimic, sh-circcbfb + pcdna3.1-atg14, or pcdna3.1-circcbfb + sh-atg14, the proliferation, cell cycle, and apoptosis of huh-7 and hcclm3 cells were detected, respectively, through mtt assay and flow cytometry. |
2022-01-23 |
2023-08-13 |
Not clear |
| Mehrdad Aghasizadeh, Tayebe Moghaddam, Ahmad Reza Bahrami, Hamid Sadeghian, Seyed Jamal Alavi, Maryam M Mati. 8-Geranyloxycarbostyril as a potent 15-LOX-1 inhibitor showed great anti-tumor effects against prostate cancer. Life sciences. 2022-01-22. PMID:35065164. |
mtt and flow cytometry tests confirmed their toxic effects on pca cells, with no significant toxicity on normal cells, and apoptosis was the main mechanism of cell death. |
2022-01-22 |
2023-08-13 |
mouse |