| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuangying Hu, Cuiqiong Yi, Zhiming Hao, Shanshan Cao, Hongtao Li, Xiaodong Shao, Jing Zhang, Taidong Qiao, Daiming Fa. The effect of somatostatin and SSTR3 on proliferation and apoptosis of gastric cancer cells. Cancer biology & therapy. vol 3. issue 8. 2005-03-29. PMID:15197339. |
the effect of octreotide on the growth of gastric cancer cells was examined by mtt test, and the apoptosis by flow cytometry. |
2005-03-29 |
2023-08-12 |
Not clear |
| Wen-Xin Li, Cheng-Bin Cui, Bing Cai, Xin-Sheng Ya. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. Journal of Asian natural products research. vol 7. issue 2. 2005-03-22. PMID:15621610. |
furthermore, the inhibitory effects of 1-5 on the proliferation of tsft210 and k562 cells have been evaluated by mtt assay to obtain ic50 values to confirm that 1-5 are anticancer components of vitex trifolia l., which exert their anti-proliferative effect on cancer cells through inducing apoptosis and inhibiting the cell cycle. |
2005-03-22 |
2023-08-12 |
Not clear |
| Wing-Kee Lee, Ulrich Bork, Fatemeh Gholamrezaei, Frank Théveno. Cd(2+)-induced cytochrome c release in apoptotic proximal tubule cells: role of mitochondrial permeability transition pore and Ca(2+) uniporter. American journal of physiology. Renal physiology. vol 288. issue 1. 2005-03-04. PMID:15339793. |
using hoechst 33342 or mtt assay, 10 mum cd(2+) induced approximately 5-10% apoptosis in pt cells at 6 and 24 h, which was associated with cytochrome c and apoptosis-inducing factor release at 24 h only. |
2005-03-04 |
2023-08-12 |
rat |
| Y Zhang, C Guo, G Y. A pilot study of fatty acid metabolism in oral squamous cell carcinoma. International journal of oral and maxillofacial surgery. vol 34. issue 1. 2005-03-01. PMID:15617971. |
the effects of cerulenin, a specific, potent, noncompetitive inhibitor of fatty acid synthase (fas), on growth of tca-83 cells and normal gingival fibroblasts was determined by the mtt method, and the effect of cerulenin on apoptosis was determined by electrophoresis of cellular dna. |
2005-03-01 |
2023-08-12 |
Not clear |
| A-M Engelbrecht, C Niesler, C Page, A Lochne. p38 and JNK have distinct regulatory functions on the development of apoptosis during simulated ischaemia and reperfusion in neonatal cardiomyocytes. Basic research in cardiology. vol 99. issue 5. 2005-02-08. PMID:15309413. |
exposure of the myocytes to si (simulated ischaemia - energy depletion induced by kcn and 2-deoxy- d-glucose) reduced cell viability, as measured by the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (mtt) assay, and stimulated apoptosis as evidenced by caspase-3 activation and poly(adp-ribose) polymerase (parp) cleavage. |
2005-02-08 |
2023-08-12 |
rat |
| Matthew L Becker, LeeAnn O Bailey, Karen L Woole. Peptide-derivatized shell-cross-linked nanoparticles. 2. Biocompatibility evaluation. Bioconjugate chemistry. vol 15. issue 4. 2005-01-31. PMID:15264857. |
the effects of sck exposure on cell viability were evaluated using a metabolic 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) and a fluorescent apoptosis assay. |
2005-01-31 |
2023-08-12 |
mouse |
| Matthew L Becker, LeeAnn O Bailey, Karen L Woole. Peptide-derivatized shell-cross-linked nanoparticles. 2. Biocompatibility evaluation. Bioconjugate chemistry. vol 15. issue 4. 2005-01-31. PMID:15264857. |
although higher levels of peptide functionalization resulted in decreased metabolic function as measured by mtt assay, significant apoptosis was not observed below 500 mg/l for all the samples. |
2005-01-31 |
2023-08-12 |
mouse |
| Hong-Yan Tong, Mao-Fang Li. [Effect of 5-aza-2'-deoxycytidine on cell of high-risk patients with myelodysplastic syndrome in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 12. issue 4. 2005-01-26. PMID:15363133. |
to investigate the effect of 5-aza-2'-deoxycytidine (5-aza-cdr) on cell of high-risk patients with myelodysplastic syndrome (mds) in vitro, the growth inhibition of mutz-1 cell induced by 5-aza-cdr was detected by mtt method; apoptosis was detected by morphological observation and translocation of phosphatidylserine (ps) was examined by flow cytometry assay; the expressions of p15ink4b, dna methyltransferases (dnmt)(1), dnmt(3a) and dnmt(3b) gene on mrna level were detected by rt-pcr; methylation of p15ink4b gene in mutz-1 cells was detected by pcr using methylation specific primer (msp). |
2005-01-26 |
2023-08-12 |
Not clear |
| Zhi-Gang Peng, Jun Luo, Ling-Hui Xia, Yan Chen, San-Jun Son. [CML cell line K562 cell apoptosis induced by mangiferin]. Zhongguo shi yan xue ye xue za zhi. vol 12. issue 5. 2005-01-26. PMID:15498116. |
the antiproliferation effects of mangiferin on k562 leukemia cells were tested by tetrazolium salt (mtt) method; the apoptosis induced by mangiferin on k562 cell line was explored by means of cell morphology, dna gel electrophoresis and flow cytometry. |
2005-01-26 |
2023-08-12 |
Not clear |
| Jia Fei, Huan Zhan. [Effect and mechanism of VEGF antisense phosphorothioate deoxynucleotides on HL-60 leukemic cells]. Zhongguo shi yan xue ye xue za zhi. vol 12. issue 5. 2005-01-26. PMID:15498126. |
after culture for 72 hours, inhibitive rate of cell growth was detected with mtt methods, viable cells were counted with trypan blue exclusion each 24 hour, cell configuration and apoptosis were observed with geimsa staining and flow cytometry respectively, level of vegf protein was detected with vegf elisa kit. |
2005-01-26 |
2023-08-12 |
Not clear |
| Ya-Wun Yang, Ching-An Wu, W J W Morro. The apoptotic and necrotic effects of tomatine adjuvant. Vaccine. vol 22. issue 17-18. 2005-01-18. PMID:15149791. |
cytotoxicity was monitored using the mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and lactate dehydrogenase release assays, apoptosis and necrosis were quantified by flow cytometry using annexin v and propidium iodide staining, and morphology was examined by hoechst 33342 staining. |
2005-01-18 |
2023-08-12 |
Not clear |
| Bettina Zödl, Mansour Sargazi, Michaela Zeiner, Norman B Roberts, Ilse Steffan, Wolfgang Marktl, Cem Ekmekciogl. Toxicological effects of iron on intestinal cells. Cell biochemistry and function. vol 22. issue 3. 2004-11-24. PMID:15124177. |
cellular damage was assessed using cell proliferation (serial cell counting), tetrazolium dye (mtt) uptake, lactate dehydrogenase (ldh) release and apoptosis studies based on caspase-3 activities. |
2004-11-24 |
2023-08-12 |
human |
| Wei-Kai Chen, Yan Chen, Jun-Xia Gu, Guo-Hui Cu. [Effect of trichostatin A on histone acetylation level and apoptosis in HL-60 cells]. Zhongguo shi yan xue ye xue za zhi. vol 12. issue 3. 2004-10-28. PMID:15228659. |
in order to explore the underlying mechanism of high effects and low toxicity of trichostatin a (tsa), the effect of tsa on growth inhibition, histone acetylation level and apoptosis in hl-60 cells and normal human peripheral blood mononuclear cells (npbmnc) were examined using mtt method, immunocytochemistry technology, and annexin-v-fitc/pi double staining flow cytometry. |
2004-10-28 |
2023-08-12 |
human |
| Ze-Lin Liu, Jian-Min Luo, Zuo-Ren Dong, Fu-Xu Wang, Xue-Jun Zhang, Jing-Ci Yang, Xing-Yan Du, Li Ya. [In vitro effects of mevastatin on the proliferation and apoptosis in human multiple myeloma cell line U266]. Zhongguo shi yan xue ye xue za zhi. vol 12. issue 3. 2004-10-28. PMID:15228663. |
in order to investigate the anti-tumor activity of 3-hydroxy-3-methylglutaryl coenzyme a (hmg-coa) reductase inhibitors and the mechanism underlying the cell proliferation and apoptosis modulated in myeloma cells, the effects of mevastatin, an hmg-coa reductase inhibitor, on cell growth, cell cycle progression and apoptosis in u266 human multiple myeloma (mm) cell line in vitro were explored by mtt colorimetric assay, morphologic observation, flow cytometry, dna gel electrophoresis, and rt-pcr. |
2004-10-28 |
2023-08-12 |
human |
| Min Zhang, Fang Liu, Wei He, Yong You, Ping Zou, Ling-Bo Li. Inhibition of Fas-mediated apoptosis in Yac-1 cell via Anti-Fas ribozyme. Acta biochimica et biophysica Sinica. vol 36. issue 3. 2004-10-19. PMID:15202504. |
after treated with anti-fas antibody (jo2), yac-1 cell viability was measured with mtt assay, caspase-3 proteolytic activity was detected, and cell apoptosis was measured according to annexin v apoptosis detecting kit. |
2004-10-19 |
2023-08-12 |
mouse |
| Sai Latha Shankar, Melissa Krupski, Bhupesh Parashar, Chidi Okwuaka, Kathy O'Guin, Sridhar Mani, Bridget Shafit-Zagard. UCN-01 alters phosphorylation of Akt and GSK3beta and induces apoptosis in six independent human neuroblastoma cell lines. Journal of neurochemistry. vol 90. issue 3. 2004-09-10. PMID:15255949. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), terminal deoxynucleotidyl transferase-mediated dutp nick-end-labeling (tunel) assays, detection of active caspase-3 and cleaved poly adp-ribose polymerase (parp) confirmed that ucn-01 induced apoptosis. |
2004-09-10 |
2023-08-12 |
human |
| Christina Löfgren, Linn Hjortsberg, Malin Blennow, Kourosh Lotfi, Christer Paul, Staffan Eriksson, Freidoun Albertion. Mechanisms of cross-resistance between nucleoside analogues and vincristine or daunorubicin in leukemic cells. Biochemical and biophysical research communications. vol 320. issue 3. 2004-08-26. PMID:15240122. |
all resistant strains exhibited cross-resistance to na (cladribine and cytosine arabinoside)-induced apoptosis, assessed by caspase-3-like activation and were less sensitive to na cytotoxicity in mtt assay. |
2004-08-26 |
2023-08-12 |
Not clear |
| Nai-Kuei Huang, Yun-Lian Lin, Jing-Jy Cheng, Wen-Lin La. Gastrodia elata prevents rat pheochromocytoma cells from serum-deprived apoptosis: the role of the MAPK family. Life sciences. vol 75. issue 13. 2004-08-25. PMID:15261768. |
in this study, differential methanol (meoh) extracts of g. elata were found to prevent serum-deprived rat pheochromocytoma (pc12) cell apoptosis by the mtt assay and hoechst staining. |
2004-08-25 |
2023-08-12 |
rat |
| Xiu-jin Ye, Mao-fang Li. Homoharringtonine induces apoptosis of endothelium and down-regulates VEGF expression of K562 cells. Journal of Zhejiang University. Science. vol 5. issue 2. 2004-08-23. PMID:14674038. |
cellular proliferation was determined by mtt assay and apoptosis was analyzed by flow cytometry. |
2004-08-23 |
2023-08-12 |
human |
| Saiko Asahara, Asomi Sato, Ahmed Ali Aljonaid, Takeshi Maru. Thyroid hormone synergizes with follicle stimulating hormone to inhibit apoptosis in porcine granulosa cells selectively from small follicles. The Kobe journal of medical sciences. vol 49. issue 5-6. 2004-08-17. PMID:15141146. |
relative viability, proliferative activity, and apoptosis of cultured granulosa cells were evaluated with 3-(4.5-dimethylahiazol-2-yl)-2,5-diphenyltetrazolium bromide [mtt] assay, ki67 expression and activated caspase-3 protein expression, respectively. |
2004-08-17 |
2023-08-12 |
Not clear |