| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gaosong Wu, Jilin Yi, Fang Di, Shengquan Zou, Xingrui L. Celecoxib inhibits proliferation and induces apoptosis via cyclooxygenase-2 pathway in human pancreatic carcinoma cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 25. issue 1. 2006-05-30. PMID:15934305. |
in order to evaluate the effects and mechanisms of celecoxib in inhibiting proliferation and inducing apoptosis on human pancreatic carcinoma cells, the anti-proliferative effect was measured by using methabenzthiazuron (mtt) assay. |
2006-05-30 |
2023-08-12 |
human |
| Xingang Li, Weikai Chen, Junxia Gu, Guohui Cui, Yan Che. Regulation of histone acetylation and apoptosis by trichostatin in HL-60 cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 6. 2006-05-18. PMID:15791844. |
in order to examine the strong anticancer action and low toxicity of trichostatin a (tsa), the effect of tsa was examined on the growth inhibition, acetylation of histone h3 and apoptosis in hl-60 cells by employing mtt, immunocytochemical techniques, and annexin-v-fitc/ pi assay. |
2006-05-18 |
2023-08-12 |
Not clear |
| Lihua Xing, Zhenxiang Zhang, Yongjian Xu, Huilan Zhang, Jianbo Li. The effects of nimesulide combined with cisplatin on lung cancer. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 2. 2006-05-03. PMID:15315158. |
to study the effects of cyclooxygenase 2 selective inhibitor nimesulide (nim) combined with cisplatin (ddp) on human lung cancer and the possible mechanisms, the proliferation and apoptosis of human lung cancer cell line a549 were evaluated by mtt reduction assay and flow cytometry respectively. |
2006-05-03 |
2023-08-12 |
mouse |
| Kaei Nasu, Masakazu Nishida, Tami Ueda, Noriyuki Takai, Sun Bing, Hisashi Narahara, Isao Miyakaw. Bufalin induces apoptosis and the G0/G1 cell cycle arrest of endometriotic stromal cells: a promising agent for the treatment of endometriosis. Molecular human reproduction. vol 11. issue 11. 2006-05-02. PMID:16390854. |
to apply bufalin to the medical treatment of endometriosis, we investigated the effects of this agent on the cell proliferation and apoptosis of cultured ovarian endometriotic cyst stromal cells (ecsc) by a modified methylthiazoletetrazolium (mtt) assay, a 5-bromo-2'-deoxyuridine (brdu) incorporation assay and internucleosomal dna fragmentation assays. |
2006-05-02 |
2023-08-12 |
Not clear |
| Cheong-Yip Ho, Chi-Fai Kim, Kwok-Nam Leung, Kwok-Pui Fung, Tak-Fu Tse, Helen Chan, Clara Bik-San La. Differential anti-tumor activity of coriolus versicolor (Yunzhi) extract through p53- and/or Bcl-2-dependent apoptotic pathway in human breast cancer cells. Cancer biology & therapy. vol 4. issue 6. 2006-04-25. PMID:15908782. |
the present study aimed to evaluate the in vitro anti-tumor activity of a standardized aqueous ethanol extract prepared from cv on four breast cancer cell lines using mtt assay, and test whether the mechanism involves apoptosis induction and modulation of p53 and bcl-2 protein expressions using cell death detection elisa, p53 and bcl-2 elisas respectively. |
2006-04-25 |
2023-08-12 |
human |
| Li Bai, Rong Zhu, Zhihong Chen, Lei Gao, Xin Zhang, Xiangdong Wang, Chunxue Ba. Potential role of short hairpin RNA targeting epidermal growth factor receptor in growth and sensitivity to drugs of human lung adenocarcinoma cells. Biochemical pharmacology. vol 71. issue 8. 2006-04-25. PMID:16442503. |
the effect of shrna targeting egfr on tumor cell growth was assessed by colony formation assay, cell cycle and apoptosis by flow cytometry, and the responsiveness of hlac lines to cytotoxic drugs by 3-[4,5-dimethylthiozol-2yl]-2,5-diphenyltetrazolium bromide [mtt] assay. |
2006-04-25 |
2023-08-12 |
human |
| Mingxin Shi, Qiufeng Cai, Luming Yao, Yubin Mao, Yanlin Ming, Gaoliang Ouyan. Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells. Cell biology international. vol 30. issue 3. 2006-04-21. PMID:16376585. |
in the present study, we have investigated the effects of curcumin on growth and apoptosis in the human ovarian cancer cell line ho-8910 by mtt assay, fluorescence microscopy, flow cytometry and western blotting. |
2006-04-21 |
2023-08-12 |
human |
| Zhiwei Wang, Yuxiang Zhang, Sanjeev Banerjee, Yiwei Li, Fazlul H Sarka. Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells. International journal of cancer. vol 118. issue 8. 2006-04-18. PMID:16284950. |
we used multiple cellular and molecular approaches such as mtt assay, apoptosis assay, gene transfection, western blotting and emsa for measuring dna binding activity of nf-kappab. |
2006-04-18 |
2023-08-12 |
Not clear |
| Hye Joung Choi, Su-Bog Yee, Sang Eun Park, Eunok Im, Jee Hyung Jung, Hae Young Chung, Yung Hyun Choi, Nam Deuk Ki. Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases. Cancer letters. vol 232. issue 2. 2006-04-06. PMID:16458118. |
petrotetrayndiol a-treated sk-mel-2 cells showed growth inhibition and induction of apoptosis in a dose-dependent manner as measured by mtt assay, fluorescent microscopy and flow cytometric analysis. |
2006-04-06 |
2023-08-12 |
human |
| P J Jenkins, S Khalaf, W Ogunkolade, K McCarthy, T David, R E Hands, D Davies, S A Busti. Differential expression of IGF-binding protein-3 in normal and malignant colon and its influence on apoptosis. Endocrine-related cancer. vol 12. issue 4. 2006-03-10. PMID:16322329. |
cell number was assessed by an mts assay (a modification of the mtt assay), and apoptosis assessed by cell morphology and facs analysis using both annexin and propidium iodide staining. |
2006-03-10 |
2023-08-12 |
human |
| Hermine Dika Nguea, Bertrand Rihn, Delphine Mahon, Jean-Luc Bernard, Aymon De Reydellet, Alain Le Fao. Effects of various man-made mineral fibers on cell apoptosis and viability. Archives of toxicology. vol 79. issue 9. 2006-01-31. PMID:15856181. |
the physical interaction between u-937 cells and mmmf was observed using scanning electron microscopy, and the cytotoxicity was evaluated by studying cell viability using mtt assay and cell apoptosis with an elisa detection kit. |
2006-01-31 |
2023-08-12 |
Not clear |
| Yan Yu, Ping Sun, Li-chun Sun, Guo-yi Liu, Guo-hua Chen, Li-hua Shang, Hong-bo Wu, Jing Hu, Yue Li, Yin-ling Mao, Guang-jie Sui, Xi-wen Su. Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin. Biochemical and biophysical research communications. vol 339. issue 1. 2006-01-31. PMID:16297858. |
it was found that depletion of mdm2 in this pattern promoted apoptosis of lovo cells and cisplatin (ddp) treated in the mdm2sirna3 transfected cell population would result in a substantial decrease by mtt colorimetry. |
2006-01-31 |
2023-08-12 |
mouse |
| Jae Hun Lee, Jaehun Cheong, Yeong Min Park, Yung Hyun Cho. Down-regulation of cyclooxygenase-2 and telomerase activity by beta-lapachone in human prostate carcinoma cells. Pharmacological research. vol 51. issue 6. 2006-01-13. PMID:15829436. |
exposure of du145 cells to beta-lapachone resulted in growth inhibition and induction of apoptosis in a dose-dependent manner as measured by mtt assay, fluorescent microscopy, and flow-cytometry analysis. |
2006-01-13 |
2023-08-12 |
human |
| Kenya Okumura, Minoru Nakase, Shinnosuke Nakamura, Madoka Inui, Kenichi Hiramoto, Toshiro Tagaw. Antitumor activity of cationic liposome-mediated Bax gene transfer in osteosarcoma cells: induction of apoptosis and caspase-independent cell death. International journal of oncology. vol 27. issue 2. 2005-12-23. PMID:16010425. |
apoptosis was detected using a tunel assay, and cell growth inhibition was determined in an mtt assay. |
2005-12-23 |
2023-08-12 |
Not clear |
| Mohammad Saleem, Satwinderjeet Kaur, Mee-Hyang Kweon, Vaqar Mustafa Adhami, Farrukh Afaq, Hasan Mukhta. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway. Carcinogenesis. vol 26. issue 11. 2005-12-13. PMID:15958516. |
lupeol caused a dose-dependent inhibition of cell growth as assessed by mtt assay and induction of apoptosis as assessed by flow cytometry, fluorescence microscopy and western blotting. |
2005-12-13 |
2023-08-12 |
human |
| Atsuo Yoshino, Yoichi Katayama, Takakazu Yokoyama, Takao Watanabe, Akiyoshi Ogino, Takashi Ota, Chiaki Komine, Takao Fukushima, Kaoru Kusam. Therapeutic implications of interferon regulatory factor (IRF)-1 and IRF-2 in diffusely infiltrating astrocytomas (DIA): response to interferon (IFN)-beta in glioblastoma cells and prognostic value for DIA. Journal of neuro-oncology. vol 74. issue 3. 2005-12-13. PMID:16187022. |
we first assessed the cytotoxic effects of ifn-beta based on a cell growth study and modified mtt assay, and then quantified the apoptosis using a sandwich enzyme immunoassay following ifn-beta treatment in the cell lines, u-87mg, t98g, and a-172. |
2005-12-13 |
2023-08-12 |
Not clear |
| Hellinida Thomadaki, Chris M Tsiapalis, Andreas Scorila. Polyadenylate polymerase modulations in human epithelioid cervix and breast cancer cell lines, treated with etoposide or cordycepin, follow cell cycle rather than apoptosis induction. Biological chemistry. vol 386. issue 5. 2005-12-12. PMID:15927891. |
induction of apoptosis was determined by endonucleosomal dna cleavage, 4'6-diamidino-2-phenylindol (dapi) staining and caspase-6 activity assay, whereas cytotoxicity and cell cycle status were assessed by trypan blue staining, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry. |
2005-12-12 |
2023-08-12 |
human |
| Ester Verdaguer, Daniel Alvira, Andrés Jiménez, Victor Rimbau, Antoni Camins, Mercè Pallà. Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons. British journal of pharmacology. vol 145. issue 8. 2005-12-02. PMID:15912127. |
zvad-fmk, a broad spectrum inhibitor of caspases, attenuates apoptosis (up to 20%) mediated by s/k deprivation and protects against cell death, as measured by mtt ([3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium]) assay. |
2005-12-02 |
2023-08-12 |
Not clear |
| Shiyan Yan, Dongsheng Zhang, Ning Gu, Jie Zheng, Anwei Ding, Ziyu Wang, Baoling Xing, Ming Ma, Yu Zhan. Therapeutic effect of Fe2O3 nanoparticles combined with magnetic fluid hyperthermia on cultured liver cancer cells and xenograft liver cancers. Journal of nanoscience and nanotechnology. vol 5. issue 8. 2005-11-22. PMID:16193975. |
we examined growth and apoptosis of smmc-7721 cells treated with mfh containing fe2o3 nanoparticles at various concentrations (2, 4, 6, and 8 g/liter) for 30-60 min by using mtt, flow cytometry (fcm), and transmission electron microscopy (tem). |
2005-11-22 |
2023-08-12 |
mouse |
| Natalia López, Javier Díez, María Antonia Fortuñ. Characterization of the protective effects of cardiotrophin-1 against non-ischemic death stimuli in adult cardiomyocytes. Cytokine. vol 30. issue 5. 2005-11-15. PMID:15927854. |
cell death was determined by trypan blue exclusion, cell viability by mtt assay and apoptosis by tunel-annexin-v staining. |
2005-11-15 |
2023-08-12 |
rat |