| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong Tang, Kaixun Huan. Inhibiting effect of selenium on oxysterols-induced apoptosis of rat vascular smooth muscle cells. Journal of inorganic biochemistry. vol 98. issue 11. 2005-10-11. PMID:15522395. |
to evaluate the cytoprotection mechanism of selenium against cholestane-3beta,5alpha,6beta-triol (3-triol)-induced vascular smooth muscle cells (vsmcs) damage, cell viability was analyzed by 3-(4,5-dimethylthiazol-2 -yl)-2,5-diphenyltetrazolium bromide (mtt) assay and cell count, the percentage release of lactate dehydrogenase (ldh) from the cell was assessed, and apoptosis was detected by dna laddering and flow cytometric analysis. |
2005-10-11 |
2023-08-12 |
rat |
| Jiajun Liu, Renwei Huang, Dongjun Lin, Xiangyuan Wu, Jun Peng, Qu Lin, Xianglin Pan, Maohong Zhang, Ming Hou, Feng Che. Apoptotic effect of oridonin on NB4 cells and its mechanism. Leukemia & lymphoma. vol 46. issue 4. 2005-10-05. PMID:16019488. |
cell growth inhibition, apoptosis and related pathways were assessed by mtt assay as well as flow cytometry (fcm) and western blot analysis. |
2005-10-05 |
2023-08-12 |
Not clear |
| Zengli Yu, Yunan Tang, Dongsheng Hu, Juan L. Inhibitory effect of genistein on mouse colon cancer MC-26 cells involved TGF-beta1/Smad pathway. Biochemical and biophysical research communications. vol 333. issue 3. 2005-09-26. PMID:15963949. |
by using adenoviral vector, we demonstrated that smad7 overexpression attenuated genistein-induced growth inhibition and apoptosis as determined by mtt and apoptosis elisa. |
2005-09-26 |
2023-08-12 |
mouse |
| Yang Yang, Takayuki Ikezoe, Tamotsu Takeuchi, Yoshihiro Adachi, Yuji Ohtsuki, Seisho Takeuchi, H Phillip Koeffler, Hirokuni Taguch. HIV-1 protease inhibitor induces growth arrest and apoptosis of human prostate cancer LNCaP cells in vitro and in vivo in conjunction with blockade of androgen receptor STAT3 and AKT signaling. Cancer science. vol 96. issue 7. 2005-09-21. PMID:16053514. |
this study found that the hiv-1 protease inhibitor nelfinavir (nfv) induced growth arrest and apoptosis of human prostate cancer cells (lncap, du145 and pc-3 cells), as measured by mtt and terminal deoxyribonucleotide transferase-mediated dutp nick end labeling (tunel) assays, respectively, on the third day of culture. |
2005-09-21 |
2023-08-12 |
mouse |
| Masahide Matsuyama, Rikio Yoshimura, Makoto Mitsuhashi, Kenji Tsuchida, Yoshiaki Takemoto, Yutaka Kawahito, Hajime Sano, Tatsuya Nakatan. 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway. Oncology reports. vol 14. issue 1. 2005-09-15. PMID:15944770. |
effects of lox inhibitors on rcc cell growth were examined by mtt assay, and hoechst staining was used to determine whether or not the lox inhibitors induce apoptosis. |
2005-09-15 |
2023-08-12 |
human |
| Xiangyi Ma, Shixuan Wang, Jianfeng Zhou, Hui Xing, Gang Xu, Beibei Wang, Gang Chen, Yun-Ping Lu, Ding M. Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides. Oncology reports. vol 14. issue 1. 2005-09-15. PMID:15944801. |
cell proliferation inhibition was determined by methyl thiazolyl tetrazolium (mtt) assay, and the induced cell apoptosis was examined using flow cytometry (fcm) after lip-asodn transfection. |
2005-09-15 |
2023-08-12 |
human |
| Anastasios Tahmatzopoulos, Shijie Sheng, Natasha Kypriano. Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis. Oncogene. vol 24. issue 34. 2005-09-01. PMID:16007219. |
the response of maspin-overexpressing clones of human prostate cancer cells du-145 to doxazosin was evaluated by determining cell viability, apoptosis and cell proliferation on the basis of the trypan blue exclusion assay/methylthiazolyldiphenyl-tetrazolium bromide (mtt) assay, hoechst staining and caspase-3 activation, and [(3)h]thymidine incorporation assay. |
2005-09-01 |
2023-08-12 |
human |
| Myoung-Hwa Lee, Mi-Hyeon Jang, Eun-Kyung Kim, Sang-Wan Han, Seong-Yeon Cho, Chang-Ju Ki. Nitric oxide induces apoptosis in mouse C2C12 myoblast cells. Journal of pharmacological sciences. vol 97. issue 3. 2005-08-29. PMID:15781989. |
to investigate whether nitric oxide (no) induces apoptosis in myoblast cells, the effect of the sodium nitroprusside (snp), no donor, on the apoptosis of mouse c2c12 myoblast cells was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry, 4,6-diamidino-2-phenylindole (dapi) staining, terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick end labeling (tunel) assay, dna fragmentation assay, reverse transcription-polymerase chain reaction (rt-pcr), western blot analysis, and caspase-3 enzyme assay. |
2005-08-29 |
2023-08-12 |
mouse |
| Jia-Jun Liu, Ren-Wei Huang, Dong-Jun Lin, Xiang-Yuan Wu, Qu Lin, Jun Peng, Xianglin Pan, Yu-Qin Song, Mao-Hong Zhang, Ming Hou, Feng Che. Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro. Oncology reports. vol 13. issue 4. 2005-08-26. PMID:15756438. |
cell viability was measured by mtt assay; cell apoptosis was assessed by flow cytometry, dna fragmentation analysis and hoechst 33258 staining. |
2005-08-26 |
2023-08-12 |
human |
| Susan M Dallabrida, Nesreen Ismail, Julianne R Oberle, Blanca E Himes, Maria A Rupnic. Angiopoietin-1 promotes cardiac and skeletal myocyte survival through integrins. Circulation research. vol 96. issue 4. 2005-08-25. PMID:15692086. |
angiopoietin-1 promoted survival of serum-starved c2c12, hsm, and ncm (mtt, trypan blue) and prevented taxol-induced apoptosis (caspase-3). |
2005-08-25 |
2023-08-12 |
mouse |
| Shu Sun, Xue-Mei Li, Xiang-Dan Li, Wan-Shan Yan. Studies on inducing apoptosis effects and mechanism of CIK cells for MGC-803 gastric cancer cell lines. Cancer biotherapy & radiopharmaceuticals. vol 20. issue 2. 2005-08-19. PMID:15869451. |
the induction of apoptosis and antiproliferation effect of cytokine-induced killer cells (cik cells) on mgc- 803 cells and its mechanisms were studied by using a tetrazolium dye-based (mtt) assay. |
2005-08-19 |
2023-08-12 |
human |
| Zsuzsanna Kocsis, Zoltán L Marcsek, Mátyás G Jakab, Béla Szende, Anna Tomp. Chemopreventive properties of trans-resveratrol against the cytotoxicity of chloroacetanilide herbicides in vitro. International journal of hygiene and environmental health. vol 208. issue 3. 2005-08-16. PMID:15971860. |
the mtt dye reduction assay was performed to test cytotoxicity, and flow cytometry to test cell proliferation and apoptosis. |
2005-08-16 |
2023-08-12 |
human |
| Jung-Mi Yun, Hoonjeong Kwon, Hasan Mukhtar, Jae-Kwan Hwan. Induction of apoptosis by Panduratin A isolated from Kaempferia pandurata in human colon cancer HT-29 cells. Planta medica. vol 71. issue 6. 2005-08-11. PMID:15971119. |
cell proliferation and induction of apoptosis was determined by the mtt assay, dna fragmentation measurement, flow cytometric analysis, nuclear staining and western blotting. |
2005-08-11 |
2023-08-12 |
human |
| Mi Ja Chung, Paul A Walker, Ray W Brown, Christer Hogstran. ZINC-mediated gene expression offers protection against H2O2-induced cytotoxicity. Toxicology and applied pharmacology. vol 205. issue 3. 2005-08-02. PMID:15922008. |
pretreatment with zinc protected the cells from subsequent cell damage and apoptosis, as assessed by lactate dehydrogenase leakage, mitochondrial dehydrogenase activity (mtt assay), caspase-3 activity, and dna fragmentation. |
2005-08-02 |
2023-08-12 |
Not clear |
| S Mijatovic, D Maksimovic-Ivanic, J Radovic, D Miljkovic, G N Kaludjerovic, T J Sabo, V Trajkovi. Aloe emodin decreases the ERK-dependent anticancer activity of cisplatin. Cellular and molecular life sciences : CMLS. vol 62. issue 11. 2005-07-28. PMID:15905960. |
the protective effect of ae was demonstrated by mtt and crystal violet assays for cell viability, and involved supression of cisplatin-induced apoptosis and necrosis, as assessed by lactate dehydrogenase release and flow cytometric analysis of dna fragmentation or phosphatidylserine exposure. |
2005-07-28 |
2023-08-12 |
Not clear |
| Gautam Banerjee, Nishma Gupta, Arun Kapoor, Govindarajan Rama. UV induced bystander signaling leading to apoptosis. Cancer letters. vol 223. issue 2. 2005-07-21. PMID:15896462. |
human keratinocytes (hacat) were exposed to uv (a+b) (uva-350-400 mj/cm2 and uvb-30 mj/cm2) which induces apoptosis as evidenced by mtt assay, dna laddering, bax and fas up-regulation. |
2005-07-21 |
2023-08-12 |
human |
| J Subhashini, S V K Mahipal, P Reddann. Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro. Cancer letters. vol 224. issue 1. 2005-07-19. PMID:15911099. |
celecoxib thus potentiates apoptosis as shown by mtt assay, cytochrome c leakage, parp cleavage, dna fragmentation, bcl-2 downregulation and possibly by inhibiting nf-kb activation. |
2005-07-19 |
2023-08-12 |
human |
| Ho-Joong Youn, Ho-Shik Kim, Mi-Hee Jeon, Jung-Hee Lee, Yun-Jee Seo, Yong-Joon Lee, Jeong-Hwa Le. Induction of caspase-independent apoptosis in H9c2 cardiomyocytes by adriamycin treatment. Molecular and cellular biochemistry. vol 270. issue 1-2. 2005-07-11. PMID:15792349. |
in contrast, caspase inhibition effectively blocked the apoptosis induced by h202 in h9c2 cells, as determined by an mtt assay or microscopy. |
2005-07-11 |
2023-08-12 |
Not clear |
| N Strakova, J Ehrmann, J Bartos, J Malikova, J Dolezel, Z Kola. Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors. Neoplasma. vol 52. issue 2. 2005-06-21. PMID:15800711. |
mtt, flow cytometry, tunel assay and immunoblotting were used for detection of changes in cell viability, proliferation, differentiation and apoptosis. |
2005-06-21 |
2023-08-12 |
human |
| Iwona Mitrus, Ewa Missol-Kolka, Andrzej Plucienniczak, Stanislaw Szal. Tumour therapy with genes encoding apoptin and E4orf4. Anticancer research. vol 25. issue 2A. 2005-06-09. PMID:15868950. |
mtt and tunel tests confirmed that both the synthesised apoptin gene and the e4orf4 gene indeed induced apoptosis in cos-7, renca and b16(f10) cell lines. |
2005-06-09 |
2023-08-12 |
Not clear |