| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wing-Kee Lee, Marouan Abouhamed, Frank Théveno. Caspase-dependent and -independent pathways for cadmium-induced apoptosis in cultured kidney proximal tubule cells. American journal of physiology. Renal physiology. vol 291. issue 4. 2006-10-26. PMID:16597613. |
using hoechst 33342/ethidium bromide nuclear staining and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) cell death assays, 10-50 microm cadmium induced apoptosis of immortalized rat kidney cells derived from the s1-segment of pt at 6 and 24 h, but necrosis at 24 h only. |
2006-10-26 |
2023-08-12 |
rat |
| Daniela Colleselli, Klaudija Bijuklic, Birgit A Mosheimer, Christian M Kähle. Inhibition of cyclooxygenase (COX)-2 affects endothelial progenitor cell proliferation. Experimental cell research. vol 312. issue 15. 2006-10-19. PMID:16893539. |
proliferation kinetics, cell cycle distribution and rate of apoptosis were analysed by mtt test and facs analysis. |
2006-10-19 |
2023-08-12 |
Not clear |
| C Bouaziz, S Abid-Essefi, A Bouslimi, E El Golli, H Bach. Cytotoxicity and related effects of T-2 toxin on cultured Vero cells. Toxicon : official journal of the International Society on Toxinology. vol 48. issue 3. 2006-10-18. PMID:16884754. |
in this study, cytotoxicity and apotosis induction by t-2 toxin was investigated in vitro on vero cell line using the mtt and the neutral red viability assays, the induction of lipid peroxidation, the decrease of macromolecule levels (protein, dna and rna), dna fragmentation and caspase-3-dependent apoptosis induction. |
2006-10-18 |
2023-08-12 |
human |
| Jie Qian, Qian Bian, Lunbiao Cui, Jianfeng Chen, Ling Song, Xinru Wan. Octylphenol induces apoptosis in cultured rat Sertoli cells. Toxicology letters. vol 166. issue 2. 2006-10-13. PMID:16893618. |
in this study, the effects of 4-tert-octylphenol (op) were examined on the viability of rat cultured sertoli cells using the mtt assay and op-induced apoptosis was detected by transmission electron microscope (tem), flow cytometric analysis and hoechst staining. |
2006-10-13 |
2023-08-12 |
rat |
| I Kausch, N Ewerdwalbesloh, H Jiang, C Doehn, S Krüger, D Jocha. [Combination treatment with antisense oligonucleotides and chemotherapy in vitro]. Der Urologe. Ausg. A. vol 44. issue 8. 2006-10-11. PMID:15843992. |
in these studies, chemotherapeutic agents have been evaluated in cell culture together with ason against the proliferation associated ki-67 gene, as well as against the apoptosis associated bcl-2 gene via rt-pcr, immunochemistry and mtt cell viability assay. |
2006-10-11 |
2023-08-12 |
Not clear |
| Zengli Yu, Ying Xin. atRA-induced apoptosis of mouse embryonic palate mesenchymal cells involves activation of MAPK pathway. Toxicology and applied pharmacology. vol 215. issue 1. 2006-09-20. PMID:16712891. |
the effects of atra on apoptosis were assessed by performing mtt assay, cell death detection elisa and flow cytometry, respectively. |
2006-09-20 |
2023-08-12 |
mouse |
| Agnieszka Pladzyk, Kota V Ramana, Naseem H Ansari, Satish K Srivastav. Aldose reductase prevents aldehyde toxicity in cultured human lens epithelial cells. Experimental eye research. vol 83. issue 2. 2006-09-15. PMID:16631166. |
the cell viability was assessed by cell counts and mtt assay, and apoptosis was measured by evaluating nucleosomal degradation and caspase-3 activation using specific elisa kits. |
2006-09-15 |
2023-08-12 |
human |
| A Duffy, A Liew, J O'Sullivan, G Avalos, A Samali, T O'Brie. Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins. Endothelium : journal of endothelial cell research. vol 13. issue 1. 2006-09-15. PMID:16885062. |
cell viability was assessed by methlythiazolydiphenyltetrazolium bromide (mtt) assay, and induction of apoptosis was assessed by hoechst staining. |
2006-09-15 |
2023-08-12 |
human |
| Jia Fei, Yuan Zhan. Prediction of VEGF mRNA antisense oligodeoxynucleotides by RNA structure software and their effects on HL60 and K562 cells. Cell biology international. vol 29. issue 9. 2006-09-07. PMID:15985377. |
their effects on cell growth, vegf protein expression and apoptosis in hl60 and k562 leukemic cells were examined, and cell numbers and viability were assessed using trypan blue dye exclusion, mtt, elisa and flow cytometry. |
2006-09-07 |
2023-08-12 |
Not clear |
| Yutaka Yamanaka, Katsuya Shiraki, Tomoko Inoue, Kazumi Miyashita, Hiroyuki Fuke, Yumi Yamaguchi, Norihiko Yamamoto, Keiichi Ito, Kazushi Sugimoto, Takeshi Nakan. COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis. International journal of molecular medicine. vol 18. issue 1. 2006-09-05. PMID:16786154. |
we also used the mtt assay and cytological analysis of dapi-stained dna to assess viability and apoptosis in two hcc cells (sk-hep1 and hle). |
2006-09-05 |
2023-08-12 |
human |
| Jing Zhang, Fei-fei She, Yue-xiu Chen, Hao Che. [Effect of recombinant plasmid of Helicobacter pylori ureB gene on gastric epithelial cell]. Wei sheng wu xue bao = Acta microbiologica Sinica. vol 45. issue 1. 2006-09-01. PMID:15847158. |
the effect of recombinant plasmid of hp ureb gene on cell phenotype was observed by fluorescence strain, on proliferation by mtt, on apoptosis and cell cycles by flow cytometry, respectively. |
2006-09-01 |
2023-08-12 |
Not clear |
| Qi Wang, S W Tsao, Tadamasa Ooka, John M Nicholls, Hiu Wing Cheung, Songbin Fu, Y C Wong, Xianghong Wan. Anti-apoptotic role of BARF1 in gastric cancer cells. Cancer letters. vol 238. issue 1. 2006-08-28. PMID:16054293. |
in addition, the effect of barf1 on gastric cancer cell proliferation and apoptosis was investigated by mtt assay, dapi staining, flow cytometry as well as western blotting. |
2006-08-28 |
2023-08-12 |
human |
| Xiaoqu Hu, Fengxi Su, Li Qin, Weijuan Jia, Chang Gong, Fengyan Yu, Jujiang Guo, Erwei Son. Stable RNA interference of ErbB-2 gene synergistic with epirubicin suppresses breast cancer growth in vitro and in vivo. Biochemical and biophysical research communications. vol 346. issue 3. 2006-08-21. PMID:16781665. |
consequently, pu6-her2shrna increased apoptosis and reduced proliferation of skbr-3 cells assayed by tunel and mtt, respectively. |
2006-08-21 |
2023-08-12 |
mouse |
| Zhen Xian Du, Hai Yan Zhang, Da Xin Gao, Hua Qin Wang, Yong Jun Li, Guo Liang Li. Antisurvivin oligonucleotides inhibit growth and induce apoptosis in human medullary thyroid carcinoma cells. Experimental & molecular medicine. vol 38. issue 3. 2006-08-18. PMID:16819281. |
in tt cells, we confirmed survivin expression and its down-regulation by asodns using rt-pcr and western blot analyses, and investigated effects of asodns on viability and growth by mtt assay and apoptosis by apoptotic analyses including dna laddering assay, acridine orange/ethidium bromide staining and flow cytometric cell cycle analysis. |
2006-08-18 |
2023-08-12 |
human |
| P Brown, M Levis, E McIntyre, M Griesemer, D Smal. Combinations of the FLT3 inhibitor CEP-701 and chemotherapy synergistically kill infant and childhood MLL-rearranged ALL cells in a sequence-dependent manner. Leukemia. vol 20. issue 8. 2006-08-16. PMID:16761017. |
mtt cytotoxicity and annexin v binding apoptosis assays were used to assess antileukemic effects. |
2006-08-16 |
2023-08-12 |
Not clear |
| Klara Stefflova, Juan Chen, Diane Marotta, Hui Li, Gang Zhen. Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ. Journal of medicinal chemistry. vol 49. issue 13. 2006-08-16. PMID:16789741. |
the apoptosis involvement and drug effectiveness were confirmed by apoptag and cell viability (mtt) assays supporting the ability of pdt-bias to induce and image apoptosis in situ. |
2006-08-16 |
2023-08-12 |
Not clear |
| Yun-Ching Chang, Kai-Xun Huang, An-Chung Huang, Yung-Chyuan Ho, Chau-Jong Wan. Hibiscus anthocyanins-rich extract inhibited LDL oxidation and oxLDL-mediated macrophages apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 44. issue 7. 2006-08-14. PMID:16473450. |
mtt assay, leukostate staining analysis and western blotting reveals that has could inhibit oxldl-induced apoptosis. |
2006-08-14 |
2023-08-12 |
Not clear |
| Enrique Castellón, Marisa Clementi, Catalina Hitschfeld, Catherine Sánchez, Dixan Benítez, Leonardo Sáenz, Héctor Contreras, Christian Huidobr. Effect of leuprolide and cetrorelix on cell growth, apoptosis, and GnRH receptor expression in primary cell cultures from human prostate carcinoma. Cancer investigation. vol 24. issue 3. 2006-08-03. PMID:16809153. |
cell growth was estimated by mtt method and apoptosis by dna fragmentation using comet assay. |
2006-08-03 |
2023-08-12 |
human |
| Gavin P Collett, Frederick C Campbel. Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. Carcinogenesis. vol 27. issue 6. 2006-08-01. PMID:16497702. |
indeed, overexpression of p65 enhanced curcumin-mediated apoptosis as assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide (mtt) assay and poly(adp-ribose) polymerase (parp) cleavage. |
2006-08-01 |
2023-08-12 |
human |
| Julia B Ewaschuk, John W Walker, Hugo Diaz, Karen L Madse. Bioproduction of conjugated linoleic acid by probiotic bacteria occurs in vitro and in vivo in mice. The Journal of nutrition. vol 136. issue 6. 2006-06-22. PMID:16702308. |
conditioned medium, containing probiotic-produced cla, reduced viability and induced apoptosis of ht-29 and caco-2 cells, as assessed by mtt assay and dna laddering, respectively. |
2006-06-22 |
2023-08-12 |
mouse |