| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fiorenza Minervini, Francesca Fornelli, Giacomo Lucivero, Ciro Romano, Angelo Viscont. T-2 toxin immunotoxicity on human B and T lymphoid cell lines. Toxicology. vol 210. issue 1. 2005-05-27. PMID:15804460. |
at a t-2 concentration of 0.01 microg/ml, apoptosis was seen in molt-4 cells by annexin v binding as early as after 4 h. t-2 toxin determined sustained (48 h) immunosuppression on both cell lines, as evaluated by brdu and mtt assays. |
2005-05-27 |
2023-08-12 |
human |
| Zoltán Marcsek, Zsuzsanna Kocsis, Mátyás Jakab, Béla Szende, Anna Tomp. The efficacy of tamoxifen in estrogen receptor-positive breast cancer cells is enhanced by a medical nutriment. Cancer biotherapy & radiopharmaceuticals. vol 19. issue 6. 2005-05-26. PMID:15665622. |
cytotoxicity was measured by mtt assay, the percentage of mitoses and apoptotic cells was determined morphologically, apoptosis and s-phase was measured by flow cytometry, and estrogen-receptor activity was determined by semiquantitative measurement of the estrogen-responsive ps2 gene mrna production. |
2005-05-26 |
2023-08-12 |
human |
| Erik Hankø, Thor Willy Ruud Hansen, Runar Almaas, Julie Lindstad, Terje Rootwel. Bilirubin induces apoptosis and necrosis in human NT2-N neurons. Pediatric research. vol 57. issue 2. 2005-05-24. PMID:15611354. |
we exposed a human teratocarcinoma-derived cell line, nt2-n neurons, to different concentrations of ucb and albumin at a 1.5 molar ratio and used multiple, independent measures of cell damage to evaluate neuronal injury after 6, 24, and 48 h. low doses of ucb (0.66, 2, and 5 microm) induced a moderate loss of 3-4[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide (mtt) cleavage accompanied by delayed morphologic changes consistent with apoptosis (2 and 5 microm). |
2005-05-24 |
2023-08-12 |
human |
| Erik Hankø, Thor Willy Ruud Hansen, Runar Almaas, Julie Lindstad, Terje Rootwel. Bilirubin induces apoptosis and necrosis in human NT2-N neurons. Pediatric research. vol 57. issue 2. 2005-05-24. PMID:15611354. |
moderate concentrations of ucb (10 and 25 microm) resulted in early (6 h) necrosis in a subset of neurons, while remaining neurons underwent progressive impairment of mtt cleavage and increasing lactate dehydrogenase (ldh) release accompanied by predominantly delayed apoptosis. |
2005-05-24 |
2023-08-12 |
human |
| Erik Hankø, Thor Willy Ruud Hansen, Runar Almaas, Julie Lindstad, Terje Rootwel. Bilirubin induces apoptosis and necrosis in human NT2-N neurons. Pediatric research. vol 57. issue 2. 2005-05-24. PMID:15611354. |
high concentrations of ucb (100 microm) induced severe impairment of mtt cleavage, extensive ldh release, and morphologic changes consistent with necrosis within 6 h. used as a positive control for apoptosis, 2 microm sts induced progressive impairment of mtt cleavage and morphologic changes consistent with apoptosis over the entire observation period. |
2005-05-24 |
2023-08-12 |
human |
| Kostas V Floros, Hellinida Thomadaki, Nikos Katsaros, Maroulio Talieri, Andreas Scorila. mRNA expression analysis of a variety of apoptosis-related genes, including the novel gene of the BCL2-family, BCL2L12, in HL-60 leukemia cells after treatment with carboplatin and doxorubicin. Biological chemistry. vol 385. issue 11. 2005-05-17. PMID:15576332. |
the kinetics of apoptosis induction and cell toxicity was investigated by dna laddering and by the mtt method, respectively. |
2005-05-17 |
2023-08-12 |
human |
| Stephen Hsu, Kajuana Farrey, John Wataha, Jill Lewis, James Borke, Baldev Singh, Haiyan Qin, Carol Lapp, David Lapp, Tuan Nguyen, George Schuste. Role of p21WAF1 in green tea polyphenol-induced growth arrest and apoptosis of oral carcinoma cells. Anticancer research. vol 25. issue 1A. 2005-05-16. PMID:15816520. |
the current study determined the impact of sirna-suppressed p21waf1 and its response to egcg on cell growth, dna synthesis and apoptosis by rt-pcr, western blot, brdu incorporation, mtt and caspase 3 activity assays. |
2005-05-16 |
2023-08-12 |
Not clear |
| Ajay K Yadav, Bholanath N Paul, Sita Naik, Ashok K Saxena, Devendra Kumar Pate. Human hemoglobin shares bioactivities ascribed to human tumor necrosis factor-alpha. Immunopharmacology and immunotoxicology. vol 26. issue 4. 2005-05-11. PMID:15658605. |
both species of hemoglobin, hemoglobin a2 and hemoglobin a0 induced apoptosis and cytotoxicity in u937 cell as measured by flow cytometry and 3-(4,5-dihydro-6-(4-(3,4-dimethoxybenzooyl)-1-piperazinyl)-2(1h)-quinoline (mtt) assay respectively. |
2005-05-11 |
2023-08-12 |
human |
| Nicole M Chandler, Jonathan J Canete, Mark P Caller. Caspase-3 drives apoptosis in pancreatic cancer cells after treatment with gemcitabine. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. vol 8. issue 8. 2005-05-05. PMID:15585396. |
proliferation was measured by mtt assay and apoptosis by propidium iodine staining. |
2005-05-05 |
2023-08-12 |
Not clear |
| Hye Joung Choi, Song-Ja Bae, Nam Deuk Kim, Jee H Jung, Yung Hyun Cho. Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., in human skin melanoma cells. International journal of molecular medicine. vol 14. issue 6. 2005-04-28. PMID:15547680. |
exposure of sk-mel-2 cells to dideoxypetrosynol a resulted in growth inhibition and induction of apoptosis in a dose-dependent manner as measured by mtt assay, fluorescent microscopy and flow cytometry analysis. |
2005-04-28 |
2023-08-12 |
human |
| Zhi-Hua Yin, Cai-Ping Ren, Feng Li, Xu-Yu Yang, Hui Li, Ming Zhao, Kai-Tai Ya. Suppression of bcl-2 gene by RNA interference increases chemosensitivity to cisplatin in nasopharyngeal carcinoma cell line CNE1. Acta biochimica et biophysica Sinica. vol 36. issue 11. 2005-04-18. PMID:15514848. |
the effect of suppressing bcl-2 by rnai on cell growth was studied, the apoptosis induction and the sensitization of cne1 cells to cisplatin were quantified by mtt assays and flow cytometry. |
2005-04-18 |
2023-08-12 |
Not clear |
| Ting Zhang, Xiaolan Chen, Lingbo Qu, Jinglan Wu, Ran Cui, Yufen Zha. Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells. Bioorganic & medicinal chemistry. vol 12. issue 23. 2005-04-13. PMID:15519155. |
the proliferation and apoptosis were detected using mtt assay, hcl denatured-methyl green-pyronin staining, pcna immunohistochemistry and tunel techniques. |
2005-04-13 |
2023-08-12 |
human |
| G G Chen, N-C Liang, J F Y Lee, U P F Chan, S H Wang, B C S Leung, K L Leun. Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway. Apoptosis : an international journal on programmed cell death. vol 9. issue 5. 2005-04-12. PMID:15314290. |
the result demonstrated that 5f significantly induced apoptosis of ht-29, as shown by mtt assay and dna fragmentation measurement. |
2005-04-12 |
2023-08-12 |
human |
| Chuangying Hu, Cuiqiong Yi, Zhiming Hao, Shanshan Cao, Hongtao Li, Xiaodong Shao, Jing Zhang, Taidong Qiao, Daiming Fa. The effect of somatostatin and SSTR3 on proliferation and apoptosis of gastric cancer cells. Cancer biology & therapy. vol 3. issue 8. 2005-03-29. PMID:15197339. |
the effect of octreotide on the growth of gastric cancer cells was examined by mtt test, and the apoptosis by flow cytometry. |
2005-03-29 |
2023-08-12 |
Not clear |
| Wen-Xin Li, Cheng-Bin Cui, Bing Cai, Xin-Sheng Ya. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. Journal of Asian natural products research. vol 7. issue 2. 2005-03-22. PMID:15621610. |
furthermore, the inhibitory effects of 1-5 on the proliferation of tsft210 and k562 cells have been evaluated by mtt assay to obtain ic50 values to confirm that 1-5 are anticancer components of vitex trifolia l., which exert their anti-proliferative effect on cancer cells through inducing apoptosis and inhibiting the cell cycle. |
2005-03-22 |
2023-08-12 |
Not clear |
| Wing-Kee Lee, Ulrich Bork, Fatemeh Gholamrezaei, Frank Théveno. Cd(2+)-induced cytochrome c release in apoptotic proximal tubule cells: role of mitochondrial permeability transition pore and Ca(2+) uniporter. American journal of physiology. Renal physiology. vol 288. issue 1. 2005-03-04. PMID:15339793. |
using hoechst 33342 or mtt assay, 10 mum cd(2+) induced approximately 5-10% apoptosis in pt cells at 6 and 24 h, which was associated with cytochrome c and apoptosis-inducing factor release at 24 h only. |
2005-03-04 |
2023-08-12 |
rat |
| Y Zhang, C Guo, G Y. A pilot study of fatty acid metabolism in oral squamous cell carcinoma. International journal of oral and maxillofacial surgery. vol 34. issue 1. 2005-03-01. PMID:15617971. |
the effects of cerulenin, a specific, potent, noncompetitive inhibitor of fatty acid synthase (fas), on growth of tca-83 cells and normal gingival fibroblasts was determined by the mtt method, and the effect of cerulenin on apoptosis was determined by electrophoresis of cellular dna. |
2005-03-01 |
2023-08-12 |
Not clear |
| A-M Engelbrecht, C Niesler, C Page, A Lochne. p38 and JNK have distinct regulatory functions on the development of apoptosis during simulated ischaemia and reperfusion in neonatal cardiomyocytes. Basic research in cardiology. vol 99. issue 5. 2005-02-08. PMID:15309413. |
exposure of the myocytes to si (simulated ischaemia - energy depletion induced by kcn and 2-deoxy- d-glucose) reduced cell viability, as measured by the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (mtt) assay, and stimulated apoptosis as evidenced by caspase-3 activation and poly(adp-ribose) polymerase (parp) cleavage. |
2005-02-08 |
2023-08-12 |
rat |
| Matthew L Becker, LeeAnn O Bailey, Karen L Woole. Peptide-derivatized shell-cross-linked nanoparticles. 2. Biocompatibility evaluation. Bioconjugate chemistry. vol 15. issue 4. 2005-01-31. PMID:15264857. |
the effects of sck exposure on cell viability were evaluated using a metabolic 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) and a fluorescent apoptosis assay. |
2005-01-31 |
2023-08-12 |
mouse |
| Matthew L Becker, LeeAnn O Bailey, Karen L Woole. Peptide-derivatized shell-cross-linked nanoparticles. 2. Biocompatibility evaluation. Bioconjugate chemistry. vol 15. issue 4. 2005-01-31. PMID:15264857. |
although higher levels of peptide functionalization resulted in decreased metabolic function as measured by mtt assay, significant apoptosis was not observed below 500 mg/l for all the samples. |
2005-01-31 |
2023-08-12 |
mouse |