| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kostas V Floros, Maroulio Talieri, Andreas Scorila. Topotecan and methotrexate alter expression of the apoptosis-related genes BCL2, FAS and BCL2L12 in leukemic HL-60 cells. Biological chemistry. vol 387. issue 12. 2007-01-24. PMID:17132110. |
the kinetics of apoptosis induction and cell toxicity were investigated by dna laddering and the mtt method, respectively. |
2007-01-24 |
2023-08-12 |
human |
| T N D Pham, M Marion, F Denizeau, C Jumari. Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 8. 2006-12-26. PMID:16809017. |
studies of nuclear morphology, chromatin condensation, and oligonucleosomal dna fragmentation demonstrate that 1-5 microm cd induces apoptosis as early as 6-12 h with minor effects on mtt activity. |
2006-12-26 |
2023-08-12 |
rat |
| Sandra Osbild, Laurent Brault, Eric Battaglia, Denyse Bagre. Resistance to cisplatin and adriamycin is associated with the inhibition of glutathione efflux in MCF-7-derived cells. Anticancer research. vol 26. issue 5A. 2006-11-30. PMID:17094488. |
cytotoxicity was evaluated by mtt assay, reactive oxygen species (ros), apoptosis and necrosis by flow cytometry, glutathione (gsh) by hplc, and bcl-2, bax and parp expression by western blot. |
2006-11-30 |
2023-08-12 |
human |
| Katsuya Shiraki, Kazushi Sugimoto, Hiroshi Okano, Hidetaka Wagayama, Katsuhiko Fujikawa, Takenari Yamanaka, Takeshi Ito, Shigeru Ohmori, Takahisa Sakai, Koujiro Takase, Takeshi Nakan. CD40 expression in HCV-associated chronic liver diseases. International journal of molecular medicine. vol 18. issue 4. 2006-11-28. PMID:16964404. |
the effect of cd40 signaling on apoptosis of hepg2 cells was assessed using the mtt assay. |
2006-11-28 |
2023-08-12 |
Not clear |
| Chris A Owen, Jamuna Selvakumaran, Ioan Notingher, Gavin Jell, Larry L Hench, Molly M Steven. In vitro toxicology evaluation of pharmaceuticals using Raman micro-spectroscopy. Journal of cellular biochemistry. vol 99. issue 1. 2006-11-06. PMID:16598770. |
dna fragmentation was confirmed by western blot analysis of apoptosis regulator protein p53 and cell metabolic activity determined by mtt assay. |
2006-11-06 |
2023-08-12 |
human |
| Hwa-Jeong Lee, Dae-Hyung Son, Sun-Kyung Lee, Jun Lee, Chang-Duk Jun, Byung-Hun Jeon, Suk-Keun Lee, Eun-Cheol Ki. Extract of Coptidis rhizoma induces cytochrome-c dependent apoptosis in immortalized and malignant human oral keratinocytes. Phytotherapy research : PTR. vol 20. issue 9. 2006-11-02. PMID:16807885. |
using water extracts of c. rhizoma, growth and apoptosis-related experiments for the treatment of multi-stage of oral cancer were carried out on immortalized human oral keratinocytes (ihok), primary oral cancer cells (hn4), metastatic oral cancer cells (hn12) and human skin keratinocytes (hacat) by mtt assay, three-dimensional (3-d) raft cultures, western blotting, cell cycle analysis, nuclear staining and cytochrome c expression related to the apoptosis signaling pathway. |
2006-11-02 |
2023-08-12 |
human |
| Anna Poma, Tania Limongi, Cinzia Pisani, Vanda Granato, Pietro Picozz. Genotoxicity induced by fine urban air particulate matter in the macrophages cell line RAW 264.7. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 6. 2006-10-30. PMID:16504459. |
the viability of macrophages was assessed by the mtt method; apoptosis by an elisa test for programmed cell death (pcd) was determined after raw 264.7 cells treatment. |
2006-10-30 |
2023-08-12 |
mouse |
| Wing-Kee Lee, Marouan Abouhamed, Frank Théveno. Caspase-dependent and -independent pathways for cadmium-induced apoptosis in cultured kidney proximal tubule cells. American journal of physiology. Renal physiology. vol 291. issue 4. 2006-10-26. PMID:16597613. |
using hoechst 33342/ethidium bromide nuclear staining and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) cell death assays, 10-50 microm cadmium induced apoptosis of immortalized rat kidney cells derived from the s1-segment of pt at 6 and 24 h, but necrosis at 24 h only. |
2006-10-26 |
2023-08-12 |
rat |
| Daniela Colleselli, Klaudija Bijuklic, Birgit A Mosheimer, Christian M Kähle. Inhibition of cyclooxygenase (COX)-2 affects endothelial progenitor cell proliferation. Experimental cell research. vol 312. issue 15. 2006-10-19. PMID:16893539. |
proliferation kinetics, cell cycle distribution and rate of apoptosis were analysed by mtt test and facs analysis. |
2006-10-19 |
2023-08-12 |
Not clear |
| C Bouaziz, S Abid-Essefi, A Bouslimi, E El Golli, H Bach. Cytotoxicity and related effects of T-2 toxin on cultured Vero cells. Toxicon : official journal of the International Society on Toxinology. vol 48. issue 3. 2006-10-18. PMID:16884754. |
in this study, cytotoxicity and apotosis induction by t-2 toxin was investigated in vitro on vero cell line using the mtt and the neutral red viability assays, the induction of lipid peroxidation, the decrease of macromolecule levels (protein, dna and rna), dna fragmentation and caspase-3-dependent apoptosis induction. |
2006-10-18 |
2023-08-12 |
human |
| Jie Qian, Qian Bian, Lunbiao Cui, Jianfeng Chen, Ling Song, Xinru Wan. Octylphenol induces apoptosis in cultured rat Sertoli cells. Toxicology letters. vol 166. issue 2. 2006-10-13. PMID:16893618. |
in this study, the effects of 4-tert-octylphenol (op) were examined on the viability of rat cultured sertoli cells using the mtt assay and op-induced apoptosis was detected by transmission electron microscope (tem), flow cytometric analysis and hoechst staining. |
2006-10-13 |
2023-08-12 |
rat |
| I Kausch, N Ewerdwalbesloh, H Jiang, C Doehn, S Krüger, D Jocha. [Combination treatment with antisense oligonucleotides and chemotherapy in vitro]. Der Urologe. Ausg. A. vol 44. issue 8. 2006-10-11. PMID:15843992. |
in these studies, chemotherapeutic agents have been evaluated in cell culture together with ason against the proliferation associated ki-67 gene, as well as against the apoptosis associated bcl-2 gene via rt-pcr, immunochemistry and mtt cell viability assay. |
2006-10-11 |
2023-08-12 |
Not clear |
| Zengli Yu, Ying Xin. atRA-induced apoptosis of mouse embryonic palate mesenchymal cells involves activation of MAPK pathway. Toxicology and applied pharmacology. vol 215. issue 1. 2006-09-20. PMID:16712891. |
the effects of atra on apoptosis were assessed by performing mtt assay, cell death detection elisa and flow cytometry, respectively. |
2006-09-20 |
2023-08-12 |
mouse |
| Agnieszka Pladzyk, Kota V Ramana, Naseem H Ansari, Satish K Srivastav. Aldose reductase prevents aldehyde toxicity in cultured human lens epithelial cells. Experimental eye research. vol 83. issue 2. 2006-09-15. PMID:16631166. |
the cell viability was assessed by cell counts and mtt assay, and apoptosis was measured by evaluating nucleosomal degradation and caspase-3 activation using specific elisa kits. |
2006-09-15 |
2023-08-12 |
human |
| A Duffy, A Liew, J O'Sullivan, G Avalos, A Samali, T O'Brie. Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins. Endothelium : journal of endothelial cell research. vol 13. issue 1. 2006-09-15. PMID:16885062. |
cell viability was assessed by methlythiazolydiphenyltetrazolium bromide (mtt) assay, and induction of apoptosis was assessed by hoechst staining. |
2006-09-15 |
2023-08-12 |
human |
| Jia Fei, Yuan Zhan. Prediction of VEGF mRNA antisense oligodeoxynucleotides by RNA structure software and their effects on HL60 and K562 cells. Cell biology international. vol 29. issue 9. 2006-09-07. PMID:15985377. |
their effects on cell growth, vegf protein expression and apoptosis in hl60 and k562 leukemic cells were examined, and cell numbers and viability were assessed using trypan blue dye exclusion, mtt, elisa and flow cytometry. |
2006-09-07 |
2023-08-12 |
Not clear |
| Yutaka Yamanaka, Katsuya Shiraki, Tomoko Inoue, Kazumi Miyashita, Hiroyuki Fuke, Yumi Yamaguchi, Norihiko Yamamoto, Keiichi Ito, Kazushi Sugimoto, Takeshi Nakan. COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis. International journal of molecular medicine. vol 18. issue 1. 2006-09-05. PMID:16786154. |
we also used the mtt assay and cytological analysis of dapi-stained dna to assess viability and apoptosis in two hcc cells (sk-hep1 and hle). |
2006-09-05 |
2023-08-12 |
human |
| Jing Zhang, Fei-fei She, Yue-xiu Chen, Hao Che. [Effect of recombinant plasmid of Helicobacter pylori ureB gene on gastric epithelial cell]. Wei sheng wu xue bao = Acta microbiologica Sinica. vol 45. issue 1. 2006-09-01. PMID:15847158. |
the effect of recombinant plasmid of hp ureb gene on cell phenotype was observed by fluorescence strain, on proliferation by mtt, on apoptosis and cell cycles by flow cytometry, respectively. |
2006-09-01 |
2023-08-12 |
Not clear |
| Qi Wang, S W Tsao, Tadamasa Ooka, John M Nicholls, Hiu Wing Cheung, Songbin Fu, Y C Wong, Xianghong Wan. Anti-apoptotic role of BARF1 in gastric cancer cells. Cancer letters. vol 238. issue 1. 2006-08-28. PMID:16054293. |
in addition, the effect of barf1 on gastric cancer cell proliferation and apoptosis was investigated by mtt assay, dapi staining, flow cytometry as well as western blotting. |
2006-08-28 |
2023-08-12 |
human |
| Xiaoqu Hu, Fengxi Su, Li Qin, Weijuan Jia, Chang Gong, Fengyan Yu, Jujiang Guo, Erwei Son. Stable RNA interference of ErbB-2 gene synergistic with epirubicin suppresses breast cancer growth in vitro and in vivo. Biochemical and biophysical research communications. vol 346. issue 3. 2006-08-21. PMID:16781665. |
consequently, pu6-her2shrna increased apoptosis and reduced proliferation of skbr-3 cells assayed by tunel and mtt, respectively. |
2006-08-21 |
2023-08-12 |
mouse |