| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanjica Jakopec, Dalibor Karlović, Klara Dubravcić, Drago Batinić, Jasna Sorić, Anamaria Brozović, Danijel Buljan, Maja Osma. Lithium effect on glutamate induced damage in glioblastoma cells. Collegium antropologicum. vol 32 Suppl 1. 2008-05-01. PMID:18405064. |
cytotoxicity of glutamate was examined by spectrophotometric mtt assay, while the expression of apoptosis related genes was examined by western blot method. |
2008-05-01 |
2023-08-12 |
human |
| Fang Yang, Yuan-li H. [Recombinant human endostatin induces apoptosis of human umbilical venous endothelial cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 7. 2008-04-24. PMID:16864091. |
to investigate the effects of human endostatin on proliferation of human umbilical venous endothelial cells, the apoptosis of the endothelial cells treated with recombinant human endostatin was examined by fluorescence method and the cell proliferation activity analyzed by mtt assay. |
2008-04-24 |
2023-08-12 |
human |
| Mei-Kuang Lu, Jing-Jy Cheng, Wen-Lin Lai, Yen-Ju Lin, Nai-Kuei Huan. Fermented Antrodia cinnamomea extract protects rat PC12 cells from serum deprivation-induced apoptosis: the role of the MAPK family. Journal of agricultural and food chemistry. vol 56. issue 3. 2008-04-24. PMID:18186605. |
serum deprivation-induced apoptosis in neuronal-like pheochromocytoma (pc12) cells was used as a cell stress model, and it was found that a. cinnamomea was effective in preventing serum-deprived apoptosis according to results of an mtt assay and hoechst staining. |
2008-04-24 |
2023-08-12 |
rat |
| Quan-zhong Chang, De-hui Hu, Ming Chen, Ying Wang, Tian-ming Ga. [Neuroprotection of chloride channel blockers against NMDA-induced apoptosis of cultured rat hippocampal neurons]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 2. 2008-04-14. PMID:16503518. |
hoechst 33258 staining and mtt assay were used to detect neuronal apoptosis and cell viability, respectively. |
2008-04-14 |
2023-08-12 |
rat |
| Lincoln A Edwards, Janet Woo, Lynsey A Huxham, Maite Verreault, Wieslawa H Dragowska, Gigi Chiu, Ashish Rajput, Alastair H Kyle, Jessica Kalra, Donald Yapp, Hong Yan, Andrew I Minchinton, David Huntsman, Tim Daynard, Dawn N Waterhouse, B Thiessen, Shoukat Dedhar, Marcel B Ball. Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK). Molecular cancer therapeutics. vol 7. issue 1. 2008-04-03. PMID:18202010. |
cell viability, cell cycle, and apoptosis were evaluated using mtt assay, flow cytometry, caspase activation, and dapi staining. |
2008-04-03 |
2023-08-12 |
mouse |
| M Zhong, L J Wike, J T Ryaby, D H Carney, B D Boyan, Z Schwart. Thrombin peptide TP508 prevents nitric oxide mediated apoptosis in chondrocytes in the endochondral developmental pathway. Biochimica et biophysica acta. vol 1783. issue 1. 2008-03-19. PMID:18023291. |
apoptosis was assessed as a function of dna fragmentation ([3h]-thymidine labeled dna fragments), tunel staining, and cell viability using the mtt assay, as well as by assessing the bcl-2/bax mrna and protein ratios and caspase-3 activity. |
2008-03-19 |
2023-08-12 |
human |
| Manli Guo, Jinhua Chen, Yingjun Zhang, Kun Chen, Chunfeng Pan, Shouzhuo Ya. Enhanced adhesion/spreading and proliferation of mammalian cells on electropolymerized porphyrin film for biosensing applications. Biosensors & bioelectronics. vol 23. issue 6. 2008-03-06. PMID:17951044. |
mtt experimental results show that the viability of cells cultured on this film is higher than on tcps, and fluorescence microscopic observation indicates that cells cultured on the film are not under apoptosis. |
2008-03-06 |
2023-08-12 |
human |
| Jie Gao, Guoqing Yang, Rongbiao Pi, Ruifang Li, Ping Wang, Huijie Zhang, Kang Le, Shaorui Chen, Peiqing Li. Tanshinone IIA protects neonatal rat cardiomyocytes from adriamycin-induced apoptosis. Translational research : the journal of laboratory and clinical medicine. vol 151. issue 2. 2008-03-04. PMID:18201675. |
primary cultured cardiomyocytes were treated with 1 micromol/l of adriamycin for 24 h with or without pretreatment with tanshinone iia (0.5-2 micromol/l) for 2 h. 3-(4,5-dimethyl thiazol-2yl)-2,5-diphenyltetrazolium bromide (mtt) assay, hoechst staining, and flow cytometry measurement were used to assess cell viability and apoptosis. |
2008-03-04 |
2023-08-12 |
rat |
| Feng-Lin Chen, Xiao-Zhong Wang, Jian-Ying Li, Jie-Ping Yu, Cai-Yun Huang, Zhi-Xin Che. 12-lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway. Digestive diseases and sciences. vol 53. issue 1. 2008-02-19. PMID:17522976. |
mtt assay revealed that the absorbance of the 12-hete-treated group was significantly (p < 0.01) higher than that of control group and that the absorbance of baicalein-treated group was significantly (p < 0.01) less than that of the control group, and that 48 h after treatment the apoptosis index of the baicalein-treated group was significantly (p < 0.01) higher than that of the untreated group and was significantly (p < 0.01) lower in the 12-hete-treated group. |
2008-02-19 |
2023-08-12 |
human |
| Daniel Alvira, Marc Yeste-Velasco, Jaume Folch, Gemma Casadesús, Mark A Smith, Mercè Pallàs, Antoni Camin. Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the Atm/p53/E2F-1 path in cerebellar granule neurons. Journal of neuroscience research. vol 85. issue 14. 2008-02-14. PMID:17638302. |
cell viability was measured by the mtt method, and apoptosis was evaluated by assessing dna fragmentation with flow cytometry or quantification of nuclear condensation. |
2008-02-14 |
2023-08-12 |
Not clear |
| M W Roomi, V Ivanov, T Kalinovsky, Aleksandra Niedzwiecki, M Rat. Inhibition of cell invasion and MMP production by a nutrient mixture in malignant liposarcoma cell line SW-872. Medical oncology (Northwood, London, England). vol 24. issue 4. 2008-02-08. PMID:17917088. |
we investigated the effect of nm on liposarcoma cell line sw-872 proliferation (mtt assay), mmp secretion (gelatinase zymography), invasion through matrigel, and apoptosis and morphology (live green caspase kit and h&e). |
2008-02-08 |
2023-08-12 |
Not clear |
| Lili Ji, Tianyu Liu, Jun Liu, Ying Chen, Zhengtao Wan. Andrographolide inhibits human hepatoma-derived Hep3B cell growth through the activation of c-Jun N-terminal kinase. Planta medica. vol 73. issue 13. 2007-12-31. PMID:17918040. |
in the current study, we found that andro significantly decreased the number of surviving hepatoma-derived hep3b cells in the mtt assay and induced cell apoptosis. |
2007-12-31 |
2023-08-12 |
human |
| b' Da Gao, Zhen Xiao, Ai-E L\\xc3\\xb. [Proliferation inhibition and apoptosis induction of K562 cells by D-limonene]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 6. 2007-12-20. PMID:17204176.' |
inhibitory effect of d-limonene on proliferation of k562 leukemia cells was assayed by mtt method and cell apoptosis was detected by flow cytometry and dna agarose gel electrophoresis, the morphologic change of k562 cells was observed by microscopy. |
2007-12-20 |
2023-08-12 |
Not clear |
| Xue-Jun Zhang, Li Wen, Fu-Xu Wang, Jian-Min Luo, Ling Pan, Xiao-Jun Liu, Xing-Yan DU, Zuo-Ren Dong, Shi-Fang Yan. [Combined effect of recombinant mutant human TRAIL and daunorubicin in inducing apoptosis of leukemia cell and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 6. 2007-12-20. PMID:17204177. |
after being treated with rmhtrail and dnr or only with rmtrail, the cytotoxic effect and the apoptosis rate in k562, u937 cells were measured by mtt assay. |
2007-12-20 |
2023-08-12 |
human |
| Xiao-Lan Wei, Zhi-Hong Mo, Biao Li, Jin-Min We. Disruption of HepG2 cell adhesion by gold nanoparticle and Paclitaxel disclosed by in situ QCM measurement. Colloids and surfaces. B, Biointerfaces. vol 59. issue 1. 2007-12-20. PMID:17566716. |
it was also found by mtt assay that gold nanoparticles of low cellular cytotoxicity enhance the antiproliferation and apoptosis of hepg2 cell induced by paclitaxel. |
2007-12-20 |
2023-08-12 |
Not clear |
| Hong-Jian Yuan, Rui-Rong Xu, Run-Sheng Ding, Sheng-Hua Jiang, Wei L. [Apoptosis of in vitro cultured BMMNC from MDS patients induced by arsenic sulfide]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 2. 2007-12-14. PMID:16638196. |
the apoptosis of mds cells induced by as2s2 solution of different concentrations were studied with mtt, flow cytometry, and rt-pcr. |
2007-12-14 |
2023-08-12 |
Not clear |
| Qing Wu, Yan Chen, Xing-Gang Li, Yuan-Yan Tan. [Regulatory effect of curcumin on p300 and HDAC1 in B-NHL cells]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 2. 2007-12-14. PMID:16638200. |
the in vitro cultured raji cells were treated with curcumin at various concentrations (6.25-50 micromol/l) and at different time points (0, 6, 12, 24 and 48 hours), the inhibitory ratio of cell growth was measured by mtt assay, the cell apoptosis rate was detected by flow cytometry with annexin v-fitc/pi double staining, the changes of p300 and hdac1 mrna expression and protein level in raji cells were determined by rt-pcr and western blot. |
2007-12-14 |
2023-08-12 |
Not clear |
| Min Ho Han, Sung Ok Kim, Gi Young Kim, Taeg Kyu Kwon, Byung Tae Choi, Won Ho Lee, Yung Hyun Cho. Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. Anti-cancer drugs. vol 18. issue 8. 2007-11-28. PMID:17667597. |
the exposure of c6 cells to sanguinarine resulted in growth inhibition and the induction of apoptosis in a dose-dependent manner, as measured by the mtt assay, fluorescence microscopy, agarose gel electrophoresis and annexin-v-based assay. |
2007-11-28 |
2023-08-12 |
rat |
| J Lin, L-Y Chen, Z-X Lin, M-L Zha. The effect of triptolide on apoptosis of glioblastoma multiforme (GBM) cells. The Journal of international medical research. vol 35. issue 5. 2007-11-13. PMID:17900403. |
cell proliferation was investigated by mtt (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide) assay and growth curve analysis, and apoptosis was assessed from genomic dna fragmentation. |
2007-11-13 |
2023-08-12 |
human |
| Lin-Na Li, Hua-Dong Zhang, Shou-Jun Yuan, Zeng-Yue Tian, Lin Wang, Zhi-Xian Su. Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway. International journal of cancer. vol 121. issue 6. 2007-11-08. PMID:17520675. |
as determined by mtt assay, flow cytometry analysis on apoptosis and indirect immunofluorescence analysis on the proliferation-associated marker ki67, art suppressed the proliferation and promoted the apoptosis of colorectal cancer cells in a dose-dependent manner. |
2007-11-08 |
2023-08-12 |
human |