| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qing Wu, Yan Chen, Xing-Gang Li, Yuan-Yan Tan. [Regulatory effect of curcumin on p300 and HDAC1 in B-NHL cells]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 2. 2007-12-14. PMID:16638200. |
the in vitro cultured raji cells were treated with curcumin at various concentrations (6.25-50 micromol/l) and at different time points (0, 6, 12, 24 and 48 hours), the inhibitory ratio of cell growth was measured by mtt assay, the cell apoptosis rate was detected by flow cytometry with annexin v-fitc/pi double staining, the changes of p300 and hdac1 mrna expression and protein level in raji cells were determined by rt-pcr and western blot. |
2007-12-14 |
2023-08-12 |
Not clear |
| Min Ho Han, Sung Ok Kim, Gi Young Kim, Taeg Kyu Kwon, Byung Tae Choi, Won Ho Lee, Yung Hyun Cho. Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. Anti-cancer drugs. vol 18. issue 8. 2007-11-28. PMID:17667597. |
the exposure of c6 cells to sanguinarine resulted in growth inhibition and the induction of apoptosis in a dose-dependent manner, as measured by the mtt assay, fluorescence microscopy, agarose gel electrophoresis and annexin-v-based assay. |
2007-11-28 |
2023-08-12 |
rat |
| J Lin, L-Y Chen, Z-X Lin, M-L Zha. The effect of triptolide on apoptosis of glioblastoma multiforme (GBM) cells. The Journal of international medical research. vol 35. issue 5. 2007-11-13. PMID:17900403. |
cell proliferation was investigated by mtt (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide) assay and growth curve analysis, and apoptosis was assessed from genomic dna fragmentation. |
2007-11-13 |
2023-08-12 |
human |
| Lin-Na Li, Hua-Dong Zhang, Shou-Jun Yuan, Zeng-Yue Tian, Lin Wang, Zhi-Xian Su. Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway. International journal of cancer. vol 121. issue 6. 2007-11-08. PMID:17520675. |
as determined by mtt assay, flow cytometry analysis on apoptosis and indirect immunofluorescence analysis on the proliferation-associated marker ki67, art suppressed the proliferation and promoted the apoptosis of colorectal cancer cells in a dose-dependent manner. |
2007-11-08 |
2023-08-12 |
human |
| Maria E Katsarou, Hellinida Thomadaki, Nikos Katsaros, Andreas Scorila. Effect of bleomycin and cisplatin on the expression profile of SRA1, a novel member of pre-mRNA splicing factors, in HL-60 human promyelocytic leukemia cells. Biological chemistry. vol 388. issue 8. 2007-11-05. PMID:17655495. |
the kinetics of apoptosis and cell toxicity were investigated by dna laddering and the mtt and trypan blue assays, respectively. |
2007-11-05 |
2023-08-12 |
human |
| Wei Wang, Bing-Zhong Sun, Hong Xie, Li-Bo Ya. [Effect of tyrosine-kinase Inhibitor on p15 gene transfected K562 cells]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 1. 2007-10-30. PMID:17490518. |
the cell survival rate was determined by mtt, cell cycle and apoptosis were detected by flow cytometry. |
2007-10-30 |
2023-08-12 |
Not clear |
| Ke Fan, Pei-Hong Chen, Chun Yua. [Apoptosis-inducing and anti-proliferation effect of interferon-alpha on U937 cells and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 1. 2007-10-30. PMID:17490520. |
the u937 cells were given with various concentrations of ifn-alpha (500, 1 000, 2,000, 3,000 and 4,000 u/l) and at different time (0, 12, 24, 36, 48 hours), the inhibitory ratio was measured by mtt assay, apoptosis rate was detected by flow cytometry (fcm), the expression of cell cycle-associated cyclin e mrna was measured by rt-pcr. |
2007-10-30 |
2023-08-12 |
Not clear |
| Li Gao, Yu-Ying Li, Zheng Zhang, Zhuan-Hua Wang, Hong-Wei Wang, Li Zhang, Lei Zh. [Apoptosis of HL-60 cells induced by recombinant common Buckwheat trypsin inhibitor]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 1. 2007-10-30. PMID:17490522. |
the inhibition rate of rbti on hl-60 cells was detected by mtt (3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide); the morphology of hl-60 nuclei was observed by fluorescence microscopy; the apoptosis cells of hl-60 detected by agarose gel electrophoresis and the changes of apoptosis rate was assayed by flow cytometry (fcm), when the hl-60 cells were treated with different concentration of rbti for 24 hours. |
2007-10-30 |
2023-08-12 |
human |
| Qi-Xin Sun, Fan-Yi Meng, Yun-Bi Fu, Li L. [Induction of apoptosis in HL-60 cells by bortezomib alone or in combination with harringtonine in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 2. 2007-10-30. PMID:17493322. |
cell proliferation was analyzed by mtt assay; the apoptosis of hl-60 cells was observed by dna gel electrophoresis, fluorescence microscopy and flow cytometry. |
2007-10-30 |
2023-08-12 |
Not clear |
| Hong Chen, Zhao-Xia Xie, Hao Jiang, Zhi-Wei Zhang, Guang-Ping Wan. [Effect of ribosomal protein L6 on drug resistance and apoptosis in K562/A02 cells]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 2. 2007-10-30. PMID:17493334. |
the chemosensitivity, apoptosis and caspase-3 activity of k562 and k562/a02 cells were evaluated by mtt assay, flow cytometer and fluorometer respectively. |
2007-10-30 |
2023-08-12 |
Not clear |
| Guo-Hua Xia, Bao-An Chen, Ze-Ye Shao, Hui-Xia Lu, Döhner Konstanze, Döhner Hartmu. Mechanism of 2-methoxyestradiol-induced apoptosis in myelodysplastic syndrome MUTZ-1 cell line. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 2. 2007-10-30. PMID:17493335. |
the study was aimed to investigate the mechanism of proliferation inhibition and apoptosis of mds-raeb mutz-1 cells induced by 2-methoxyestradiol (2-me), the cell proliferation was determined by mtt assay, apoptosis rate was determined with annexinv-fitc/pi double staining and cell cycle was analyzed by flow cytometry (fcm) after mutz-1 cells were treated with different concentrations of 2-me; the changes of morphologic features of mutz-1 cells were observed with wright-giemsa's staining; lactate dehydrogenase was determined by beckman counter; and agarose gel electrophoresis was used to verify whether 2-me can induce apoptosis of mutz-1 cells. |
2007-10-30 |
2023-08-12 |
Not clear |
| Wing-Kee Lee, Blazej Torchalski, Frank Théveno. Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells. American journal of physiology. Cell physiology. vol 293. issue 3. 2007-10-29. PMID:17596294. |
inhibition of ceramide synthase with fumonisin b(1) (3 microm) prevents ceramide formation at 3 h and abolishes calpain activation at 6 h, which is associated with significant attenuation of apoptosis at 3-6 h with hoechst 33342 nuclear staining and/or 3(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) death assays. |
2007-10-29 |
2023-08-12 |
Not clear |
| Johanna C Sierra, Giovanni Suarez, Jian Sha, Sheri M Foltz, Vsevolod L Popov, Cristi L Galindo, Harold R Garner, Ashok K Chopr. Biological characterization of a new type III secretion system effector from a clinical isolate of Aeromonas hydrophila-part II. Microbial pathogenesis. vol 43. issue 4. 2007-10-25. PMID:17582731. |
apoptosis of hela cells expressing and producing aexu was confirmed by 7-amino actinomycin d (7-aad) and mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrasodium bromide] assays, by detection of cytoplasmic histone-associated dna fragments, and by activation of caspases 3 and 9. |
2007-10-25 |
2023-08-12 |
mouse |
| W Glienke, L Maute, U Koehl, R Esser, E Milz, L Bergman. Effective treatment of leukemic cell lines with wt1 siRNA. Leukemia. vol 21. issue 10. 2007-10-25. PMID:17690705. |
mtt assay was used to measure the cell viability and flow cytometry using annexin v/pi-staining for apoptosis. |
2007-10-25 |
2023-08-12 |
human |
| Guang-Xun Gao, Xie-Qun Chen, Yong-Qing Zhang, Qing-Xian Bai, Gao-Sheng Huang, Wei-Ping Zhang, Rong Liang, Bao-Xia Dong, Dong-Mei Han, Fan-Mei Ge, Zhe Wang, Hua-Feng Zh. [Rac1 expression and its effects on the cell cycle progression and apoptosis in human acute leukemic cell line HL-60]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 1. 2007-10-19. PMID:16584582. |
after transfection of hl-60 cells with different concentrations of rac1 antisense oligodeoxynucleotide (asodn) by means of fugene6, the survival, cell cycle, apoptosis of hl-60 cells were observed through mtt assay, fcm test, wright-giemsa, acridine orange/ethidium bromide (ao/eb) and annexin v-fitc/pi staining test respectively. |
2007-10-19 |
2023-08-12 |
human |
| Jie Sun, Zhongwei Dai, Yan Zhao, Guo-Qiang Che. In vitro effect of oligo-hydroxyalkanoates on the growth of mouse fibroblast cell line L929. Biomaterials. vol 28. issue 27. 2007-10-19. PMID:17574664. |
the methylthiazol tetrazolium (mtt) assay, a cell apoptosis study and the flow cytometry were used to evaluate cell viability of mouse fibroblast l929. |
2007-10-19 |
2023-08-12 |
mouse |
| Cheng Chang, Pei-Yan Kong, Xing-Hua Chen, Xian-Gui Peng, Lin Liu, Hong Liu, Dong-Feng Zeng, Xue Liang, Qing-Yu Wan. [Effect of the NHE-1-specific inhibitor DMA on pHi, proliferation and apoptosis of HL-60/ADM cells in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 3. 2007-10-16. PMID:16800927. |
after treatment with dma at different doses, phi of hl-60 and hl-60/adm cell lines were determined by using ph-sensitive fluorescence dye becef-am; the rate of growth inhibition of cells was detected with mtt assay; cell cycle was detected by flow cytometric dna analysis; cell apoptosis was observed with terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel). |
2007-10-16 |
2023-08-12 |
Not clear |
| Cheol Park, Dong-Oh Moon, Il-Whan Choi, Byung Tae Choi, Taek-Jeong Nam, Chung-Ho Rhu, Taeg Kyu Kwon, Won Ho Lee, Gi-Young Kim, Yung Hyun Cho. Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. International journal of molecular medicine. vol 20. issue 3. 2007-10-11. PMID:17671742. |
exposure of the synovial fibroblasts to curcumin resulted in growth inhibition and the induction of apoptosis, as measured by mtt assay, fluorescent microscopy and annexin-v-based assay. |
2007-10-11 |
2023-08-12 |
Not clear |
| Zhaohui Chen, Huafang Wang, Longjie Gu, Zhewei Ye, Yajun Xia. Tumor necrosis factor-related apoptosis ligand induces apoptosis in prostate cancer PC-3M cell line. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 25. issue 4. 2007-10-09. PMID:16196298. |
our results showed that apoptosis of pc-3m cells could be induced by treatment with trail for at most 4 h. the results of flow cytometry and mtt colorimetry demonstrated a time- and concentration-dependent relationship between cell apoptosis rate and trail concentration. |
2007-10-09 |
2023-08-12 |
Not clear |
| Wei Xiang, Xianli Zhu, Hongyang Zha. Effect of wild-type p53 gene transfection on the growth and radiotherapeutic sensitivity of human glioma cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 25. issue 4. 2007-10-09. PMID:16196300. |
p53 gene expression in transfected cells was detected by rt-pcr, and the cell growth inhibition and apoptosis in the absence or presence of irradiation were assessed by mtt and flow cytometry. |
2007-10-09 |
2023-08-12 |
human |