| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenya Okumura, Minoru Nakase, Shinnosuke Nakamura, Madoka Inui, Kenichi Hiramoto, Toshiro Tagaw. Antitumor activity of cationic liposome-mediated Bax gene transfer in osteosarcoma cells: induction of apoptosis and caspase-independent cell death. International journal of oncology. vol 27. issue 2. 2005-12-23. PMID:16010425. |
apoptosis was detected using a tunel assay, and cell growth inhibition was determined in an mtt assay. |
2005-12-23 |
2023-08-12 |
Not clear |
| Mohammad Saleem, Satwinderjeet Kaur, Mee-Hyang Kweon, Vaqar Mustafa Adhami, Farrukh Afaq, Hasan Mukhta. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway. Carcinogenesis. vol 26. issue 11. 2005-12-13. PMID:15958516. |
lupeol caused a dose-dependent inhibition of cell growth as assessed by mtt assay and induction of apoptosis as assessed by flow cytometry, fluorescence microscopy and western blotting. |
2005-12-13 |
2023-08-12 |
human |
| Atsuo Yoshino, Yoichi Katayama, Takakazu Yokoyama, Takao Watanabe, Akiyoshi Ogino, Takashi Ota, Chiaki Komine, Takao Fukushima, Kaoru Kusam. Therapeutic implications of interferon regulatory factor (IRF)-1 and IRF-2 in diffusely infiltrating astrocytomas (DIA): response to interferon (IFN)-beta in glioblastoma cells and prognostic value for DIA. Journal of neuro-oncology. vol 74. issue 3. 2005-12-13. PMID:16187022. |
we first assessed the cytotoxic effects of ifn-beta based on a cell growth study and modified mtt assay, and then quantified the apoptosis using a sandwich enzyme immunoassay following ifn-beta treatment in the cell lines, u-87mg, t98g, and a-172. |
2005-12-13 |
2023-08-12 |
Not clear |
| Hellinida Thomadaki, Chris M Tsiapalis, Andreas Scorila. Polyadenylate polymerase modulations in human epithelioid cervix and breast cancer cell lines, treated with etoposide or cordycepin, follow cell cycle rather than apoptosis induction. Biological chemistry. vol 386. issue 5. 2005-12-12. PMID:15927891. |
induction of apoptosis was determined by endonucleosomal dna cleavage, 4'6-diamidino-2-phenylindol (dapi) staining and caspase-6 activity assay, whereas cytotoxicity and cell cycle status were assessed by trypan blue staining, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry. |
2005-12-12 |
2023-08-12 |
human |
| Ester Verdaguer, Daniel Alvira, Andrés Jiménez, Victor Rimbau, Antoni Camins, Mercè Pallà. Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons. British journal of pharmacology. vol 145. issue 8. 2005-12-02. PMID:15912127. |
zvad-fmk, a broad spectrum inhibitor of caspases, attenuates apoptosis (up to 20%) mediated by s/k deprivation and protects against cell death, as measured by mtt ([3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium]) assay. |
2005-12-02 |
2023-08-12 |
Not clear |
| Shiyan Yan, Dongsheng Zhang, Ning Gu, Jie Zheng, Anwei Ding, Ziyu Wang, Baoling Xing, Ming Ma, Yu Zhan. Therapeutic effect of Fe2O3 nanoparticles combined with magnetic fluid hyperthermia on cultured liver cancer cells and xenograft liver cancers. Journal of nanoscience and nanotechnology. vol 5. issue 8. 2005-11-22. PMID:16193975. |
we examined growth and apoptosis of smmc-7721 cells treated with mfh containing fe2o3 nanoparticles at various concentrations (2, 4, 6, and 8 g/liter) for 30-60 min by using mtt, flow cytometry (fcm), and transmission electron microscopy (tem). |
2005-11-22 |
2023-08-12 |
mouse |
| Natalia López, Javier Díez, María Antonia Fortuñ. Characterization of the protective effects of cardiotrophin-1 against non-ischemic death stimuli in adult cardiomyocytes. Cytokine. vol 30. issue 5. 2005-11-15. PMID:15927854. |
cell death was determined by trypan blue exclusion, cell viability by mtt assay and apoptosis by tunel-annexin-v staining. |
2005-11-15 |
2023-08-12 |
rat |
| Rong Tang, Kaixun Huan. Inhibiting effect of selenium on oxysterols-induced apoptosis of rat vascular smooth muscle cells. Journal of inorganic biochemistry. vol 98. issue 11. 2005-10-11. PMID:15522395. |
to evaluate the cytoprotection mechanism of selenium against cholestane-3beta,5alpha,6beta-triol (3-triol)-induced vascular smooth muscle cells (vsmcs) damage, cell viability was analyzed by 3-(4,5-dimethylthiazol-2 -yl)-2,5-diphenyltetrazolium bromide (mtt) assay and cell count, the percentage release of lactate dehydrogenase (ldh) from the cell was assessed, and apoptosis was detected by dna laddering and flow cytometric analysis. |
2005-10-11 |
2023-08-12 |
rat |
| Jiajun Liu, Renwei Huang, Dongjun Lin, Xiangyuan Wu, Jun Peng, Qu Lin, Xianglin Pan, Maohong Zhang, Ming Hou, Feng Che. Apoptotic effect of oridonin on NB4 cells and its mechanism. Leukemia & lymphoma. vol 46. issue 4. 2005-10-05. PMID:16019488. |
cell growth inhibition, apoptosis and related pathways were assessed by mtt assay as well as flow cytometry (fcm) and western blot analysis. |
2005-10-05 |
2023-08-12 |
Not clear |
| Zengli Yu, Yunan Tang, Dongsheng Hu, Juan L. Inhibitory effect of genistein on mouse colon cancer MC-26 cells involved TGF-beta1/Smad pathway. Biochemical and biophysical research communications. vol 333. issue 3. 2005-09-26. PMID:15963949. |
by using adenoviral vector, we demonstrated that smad7 overexpression attenuated genistein-induced growth inhibition and apoptosis as determined by mtt and apoptosis elisa. |
2005-09-26 |
2023-08-12 |
mouse |
| Yang Yang, Takayuki Ikezoe, Tamotsu Takeuchi, Yoshihiro Adachi, Yuji Ohtsuki, Seisho Takeuchi, H Phillip Koeffler, Hirokuni Taguch. HIV-1 protease inhibitor induces growth arrest and apoptosis of human prostate cancer LNCaP cells in vitro and in vivo in conjunction with blockade of androgen receptor STAT3 and AKT signaling. Cancer science. vol 96. issue 7. 2005-09-21. PMID:16053514. |
this study found that the hiv-1 protease inhibitor nelfinavir (nfv) induced growth arrest and apoptosis of human prostate cancer cells (lncap, du145 and pc-3 cells), as measured by mtt and terminal deoxyribonucleotide transferase-mediated dutp nick end labeling (tunel) assays, respectively, on the third day of culture. |
2005-09-21 |
2023-08-12 |
mouse |
| Masahide Matsuyama, Rikio Yoshimura, Makoto Mitsuhashi, Kenji Tsuchida, Yoshiaki Takemoto, Yutaka Kawahito, Hajime Sano, Tatsuya Nakatan. 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway. Oncology reports. vol 14. issue 1. 2005-09-15. PMID:15944770. |
effects of lox inhibitors on rcc cell growth were examined by mtt assay, and hoechst staining was used to determine whether or not the lox inhibitors induce apoptosis. |
2005-09-15 |
2023-08-12 |
human |
| Xiangyi Ma, Shixuan Wang, Jianfeng Zhou, Hui Xing, Gang Xu, Beibei Wang, Gang Chen, Yun-Ping Lu, Ding M. Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides. Oncology reports. vol 14. issue 1. 2005-09-15. PMID:15944801. |
cell proliferation inhibition was determined by methyl thiazolyl tetrazolium (mtt) assay, and the induced cell apoptosis was examined using flow cytometry (fcm) after lip-asodn transfection. |
2005-09-15 |
2023-08-12 |
human |
| Anastasios Tahmatzopoulos, Shijie Sheng, Natasha Kypriano. Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis. Oncogene. vol 24. issue 34. 2005-09-01. PMID:16007219. |
the response of maspin-overexpressing clones of human prostate cancer cells du-145 to doxazosin was evaluated by determining cell viability, apoptosis and cell proliferation on the basis of the trypan blue exclusion assay/methylthiazolyldiphenyl-tetrazolium bromide (mtt) assay, hoechst staining and caspase-3 activation, and [(3)h]thymidine incorporation assay. |
2005-09-01 |
2023-08-12 |
human |
| Myoung-Hwa Lee, Mi-Hyeon Jang, Eun-Kyung Kim, Sang-Wan Han, Seong-Yeon Cho, Chang-Ju Ki. Nitric oxide induces apoptosis in mouse C2C12 myoblast cells. Journal of pharmacological sciences. vol 97. issue 3. 2005-08-29. PMID:15781989. |
to investigate whether nitric oxide (no) induces apoptosis in myoblast cells, the effect of the sodium nitroprusside (snp), no donor, on the apoptosis of mouse c2c12 myoblast cells was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry, 4,6-diamidino-2-phenylindole (dapi) staining, terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick end labeling (tunel) assay, dna fragmentation assay, reverse transcription-polymerase chain reaction (rt-pcr), western blot analysis, and caspase-3 enzyme assay. |
2005-08-29 |
2023-08-12 |
mouse |
| Jia-Jun Liu, Ren-Wei Huang, Dong-Jun Lin, Xiang-Yuan Wu, Qu Lin, Jun Peng, Xianglin Pan, Yu-Qin Song, Mao-Hong Zhang, Ming Hou, Feng Che. Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro. Oncology reports. vol 13. issue 4. 2005-08-26. PMID:15756438. |
cell viability was measured by mtt assay; cell apoptosis was assessed by flow cytometry, dna fragmentation analysis and hoechst 33258 staining. |
2005-08-26 |
2023-08-12 |
human |
| Susan M Dallabrida, Nesreen Ismail, Julianne R Oberle, Blanca E Himes, Maria A Rupnic. Angiopoietin-1 promotes cardiac and skeletal myocyte survival through integrins. Circulation research. vol 96. issue 4. 2005-08-25. PMID:15692086. |
angiopoietin-1 promoted survival of serum-starved c2c12, hsm, and ncm (mtt, trypan blue) and prevented taxol-induced apoptosis (caspase-3). |
2005-08-25 |
2023-08-12 |
mouse |
| Shu Sun, Xue-Mei Li, Xiang-Dan Li, Wan-Shan Yan. Studies on inducing apoptosis effects and mechanism of CIK cells for MGC-803 gastric cancer cell lines. Cancer biotherapy & radiopharmaceuticals. vol 20. issue 2. 2005-08-19. PMID:15869451. |
the induction of apoptosis and antiproliferation effect of cytokine-induced killer cells (cik cells) on mgc- 803 cells and its mechanisms were studied by using a tetrazolium dye-based (mtt) assay. |
2005-08-19 |
2023-08-12 |
human |
| Zsuzsanna Kocsis, Zoltán L Marcsek, Mátyás G Jakab, Béla Szende, Anna Tomp. Chemopreventive properties of trans-resveratrol against the cytotoxicity of chloroacetanilide herbicides in vitro. International journal of hygiene and environmental health. vol 208. issue 3. 2005-08-16. PMID:15971860. |
the mtt dye reduction assay was performed to test cytotoxicity, and flow cytometry to test cell proliferation and apoptosis. |
2005-08-16 |
2023-08-12 |
human |
| Jung-Mi Yun, Hoonjeong Kwon, Hasan Mukhtar, Jae-Kwan Hwan. Induction of apoptosis by Panduratin A isolated from Kaempferia pandurata in human colon cancer HT-29 cells. Planta medica. vol 71. issue 6. 2005-08-11. PMID:15971119. |
cell proliferation and induction of apoptosis was determined by the mtt assay, dna fragmentation measurement, flow cytometric analysis, nuclear staining and western blotting. |
2005-08-11 |
2023-08-12 |
human |