| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dixan A Benitez, Eulalia Pozo-Guisado, Alberto Alvarez-Barrientos, Pedro M Fernandez-Salguero, Enrique A Castelló. Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines. Journal of andrology. vol 28. issue 2. 2007-04-12. PMID:17050787. |
apoptosis and cell cycle distribution were evaluated by flow cytometry and proliferation by mtt assay and direct cell counting. |
2007-04-12 |
2023-08-12 |
Not clear |
| Kyung-Mi Kim, Seung-Gyu Lee, Min-Gyu Park, Jea-Young Song, Hyung-Lyun Kang, Woo-Kon Lee, Myung-Je Cho, Kwang-Ho Rhee, Hee-Shang Youn, Seung-Chul Bai. Gamma-glutamyltranspeptidase of Helicobacter pylori induces mitochondria-mediated apoptosis in AGS cells. Biochemical and biophysical research communications. vol 355. issue 2. 2007-04-12. PMID:17307146. |
recombinant ggt induced apoptosis in ags cells in a time-dependent manner, which was confirmed by tunel staining, the mtt assay and immunoblot analysis for caspases-9, -3, bax, bcl-2, bcl-xl and cytochrome c release. |
2007-04-12 |
2023-08-12 |
Not clear |
| Guido Seitz, Steven W Warmann, Sorin Armeanu, Heike Heitmann, Peter Ruck, Robert M Hoffman, Jörg Fuchs, Johannes T Wessel. In vitro photodynamic therapy of childhood rhabdomyosarcoma. International journal of oncology. vol 30. issue 3. 2007-03-29. PMID:17273762. |
cancer cells were investigated for cell viability (mtt assay), proliferative activity (ki-67 assay), and apoptosis (tunel test). |
2007-03-29 |
2023-08-12 |
Not clear |
| J D Arditi, M Venihaki, K P Karalis, G P Chrouso. Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancer. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 39. issue 1. 2007-03-28. PMID:17226107. |
the proliferation rate of the mcf7 cells was measured using the mtt method, while apoptosis was examined by quantifying the dna fragmentation using an elisa assay. |
2007-03-28 |
2023-08-12 |
human |
| A M Grabowska, J Hughes, S A Watso. Use of interfering RNA to investigate the role of endogenous gastrin in the survival of gastrointestinal cancer cells. British journal of cancer. vol 96. issue 3. 2007-03-21. PMID:17262081. |
the most effective sirna was tested in a panel of gi cancer cell lines at various concentrations and time points, and the effect on cell survival and apoptosis was measured using methyl thiazoyl tetrazolium (mtt) and caspase 3 activation assays. |
2007-03-21 |
2023-08-12 |
human |
| Wenzhu Li, Shengyu Wang, Caixia Chen, Guohong Zhuan. Induction of tumor cell apoptosis via Fas/DR5. Cellular & molecular immunology. vol 3. issue 6. 2007-03-20. PMID:17257501. |
cytotoxicity exerted by fasl/anti-dr5 mab on tumor cell lines was measured by mtt assay and the induced apoptosis was determined by agarose gel electrophoresis. |
2007-03-20 |
2023-08-12 |
Not clear |
| Liansheng Wang, Yongzhen Yang, Seema Dwivedi, Ya Xu, Etem T Chu, Jie Li, Kimberlyn Fitchett, Paul J Boo. Manipulating glutathione-S-transferases may prevent the development of tolerance to nitroglycerin. Cardiovascular toxicology. vol 6. issue 2. 2007-03-07. PMID:17303920. |
mtt cytotoxicity, apoptosis, nitric oxide (no) synthases, both endothelial no synthase (enos) and inducible no synthase (inos) and cyclic guanosine mono-phosphate (cgmp) were measured. |
2007-03-07 |
2023-08-12 |
mouse |
| Jun Chen, Xin-Qiang Xiao, Chun-Ming Deng, Xian-Shi Su, Gui-Yuan L. Downregulation of xIAP expression by small interfering RNA inhibits cellular viability and increases chemosensitivity to methotrexate in human hepatoma cell line HepG2. Journal of chemotherapy (Florence, Italy). vol 18. issue 5. 2007-03-02. PMID:17127230. |
t he suppression efficiency o f xiapby rnai was evaluated using the mtt assay for cellular viability and annexin v-pi binding assay for apoptosis. |
2007-03-02 |
2023-08-12 |
human |
| Jan-Ying Yeh, Bor-Rung Ou, Yu-Chuan Liang, Joel Burchfiel, Judy A Butler, Neil E Forsberg, Philip D Whange. Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 19. issue 6. 2007-02-26. PMID:16951906. |
c6 rat glial cells were incubated with graded concentrations up to 1000 nm of selenite, selenate, selenomethionine (sem), se-methyl-selenocysteine (semcys), high-se broccoli (h-seb) extract or low-se broccoli (l-seb) extract for 24 and 48 h. mtt results indicated that all se sources and levels examined inhibited c6 cell proliferation at 48 h. the results from cell cycle progression and apoptosis analysis indicated that sem, semcys, h-seb or l-seb treatments at the concentration of 1000 nm reduced the cell population in g(0)/g(1) phase, but induced g(2)/m phase arrest and increased apoptosis and secondary necrosis in c6 cells at 24 h. the populations of apoptotic cells and secondary necrotic cells were increased by all se sources examined. |
2007-02-26 |
2023-08-12 |
rat |
| Jia-Jun Liu, Dong-Jun Lin, Pei-Qing Liu, Min Huang, Xu-Dong Li, Ren-Wei Huan. Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro. Journal of biomedical science. vol 13. issue 6. 2007-02-22. PMID:16955348. |
cell proliferation was assessed by mtt assay, cell apoptosis was observed by hoechst 33258 staining and flow cytometry (fcm); the variation of caspase-3 and apoptotic related genes were assayed by western blotting, cell mitochondrial membrane potential as well as cell adhesive and invasive effects were also investigated by using standard methods. |
2007-02-22 |
2023-08-12 |
Not clear |
| O H Temmink, H-J Prins, E van Gelderop, G J Peter. The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells. British journal of cancer. vol 96. issue 1. 2007-02-22. PMID:17179993. |
the cells were retrieved from the fibres and assayed for growth (mtt assay), cell cycle distribution (flow cytometry) and apoptosis induction (fragel method). |
2007-02-22 |
2023-08-12 |
mouse |
| András Hrabák, Gyöngyi Bökönyi, László Orfi, Tamás Bajor, György Kér. Comparison of the cytotoxic effects of receptor tyrosine kinase inhibitors on macrophage functions; possible side effects in the immune defense. Immunology letters. vol 107. issue 2. 2007-02-05. PMID:17098294. |
nevertheless, these damaging effects of the inhibitors did not reduce the anti-tumor effect of the rtk inhibitors on cos 7 cells as evidenced by mtt test and apoptosis study. |
2007-02-05 |
2023-08-12 |
rat |
| G Bartolini, M Orlandi, A Papi, K Ammar, F Guerra, A M Ferreri, P Rocch. A search for multidrug resistance modulators: the effects of retinoids in human colon carcinoma cells. In vivo (Athens, Greece). vol 20. issue 6A. 2007-01-26. PMID:17203756. |
cell proliferation was measured by mtt assay, apoptosis was evaluated using dna fragmentation and annexin v detection assay. |
2007-01-26 |
2023-08-12 |
human |
| Kostas V Floros, Maroulio Talieri, Andreas Scorila. Topotecan and methotrexate alter expression of the apoptosis-related genes BCL2, FAS and BCL2L12 in leukemic HL-60 cells. Biological chemistry. vol 387. issue 12. 2007-01-24. PMID:17132110. |
the kinetics of apoptosis induction and cell toxicity were investigated by dna laddering and the mtt method, respectively. |
2007-01-24 |
2023-08-12 |
human |
| T N D Pham, M Marion, F Denizeau, C Jumari. Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 8. 2006-12-26. PMID:16809017. |
studies of nuclear morphology, chromatin condensation, and oligonucleosomal dna fragmentation demonstrate that 1-5 microm cd induces apoptosis as early as 6-12 h with minor effects on mtt activity. |
2006-12-26 |
2023-08-12 |
rat |
| Sandra Osbild, Laurent Brault, Eric Battaglia, Denyse Bagre. Resistance to cisplatin and adriamycin is associated with the inhibition of glutathione efflux in MCF-7-derived cells. Anticancer research. vol 26. issue 5A. 2006-11-30. PMID:17094488. |
cytotoxicity was evaluated by mtt assay, reactive oxygen species (ros), apoptosis and necrosis by flow cytometry, glutathione (gsh) by hplc, and bcl-2, bax and parp expression by western blot. |
2006-11-30 |
2023-08-12 |
human |
| Katsuya Shiraki, Kazushi Sugimoto, Hiroshi Okano, Hidetaka Wagayama, Katsuhiko Fujikawa, Takenari Yamanaka, Takeshi Ito, Shigeru Ohmori, Takahisa Sakai, Koujiro Takase, Takeshi Nakan. CD40 expression in HCV-associated chronic liver diseases. International journal of molecular medicine. vol 18. issue 4. 2006-11-28. PMID:16964404. |
the effect of cd40 signaling on apoptosis of hepg2 cells was assessed using the mtt assay. |
2006-11-28 |
2023-08-12 |
Not clear |
| Chris A Owen, Jamuna Selvakumaran, Ioan Notingher, Gavin Jell, Larry L Hench, Molly M Steven. In vitro toxicology evaluation of pharmaceuticals using Raman micro-spectroscopy. Journal of cellular biochemistry. vol 99. issue 1. 2006-11-06. PMID:16598770. |
dna fragmentation was confirmed by western blot analysis of apoptosis regulator protein p53 and cell metabolic activity determined by mtt assay. |
2006-11-06 |
2023-08-12 |
human |
| Hwa-Jeong Lee, Dae-Hyung Son, Sun-Kyung Lee, Jun Lee, Chang-Duk Jun, Byung-Hun Jeon, Suk-Keun Lee, Eun-Cheol Ki. Extract of Coptidis rhizoma induces cytochrome-c dependent apoptosis in immortalized and malignant human oral keratinocytes. Phytotherapy research : PTR. vol 20. issue 9. 2006-11-02. PMID:16807885. |
using water extracts of c. rhizoma, growth and apoptosis-related experiments for the treatment of multi-stage of oral cancer were carried out on immortalized human oral keratinocytes (ihok), primary oral cancer cells (hn4), metastatic oral cancer cells (hn12) and human skin keratinocytes (hacat) by mtt assay, three-dimensional (3-d) raft cultures, western blotting, cell cycle analysis, nuclear staining and cytochrome c expression related to the apoptosis signaling pathway. |
2006-11-02 |
2023-08-12 |
human |
| Anna Poma, Tania Limongi, Cinzia Pisani, Vanda Granato, Pietro Picozz. Genotoxicity induced by fine urban air particulate matter in the macrophages cell line RAW 264.7. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 6. 2006-10-30. PMID:16504459. |
the viability of macrophages was assessed by the mtt method; apoptosis by an elisa test for programmed cell death (pcd) was determined after raw 264.7 cells treatment. |
2006-10-30 |
2023-08-12 |
mouse |