| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asfar S Azmi, Amro Aboukameel, Sanjeev Banerjee, Zhiwei Wang, Momin Mohammad, Jack Wu, Shaomeng Wang, Dajun Yang, Philip A Philip, Fazlul H Sarkar, Ramzi M Mohamma. MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function. European journal of cancer (Oxford, England : 1990). vol 46. issue 6. 2010-06-14. PMID:20156675. |
mi-319-cisplatin combination synergistically suppressed cell growth (mtt combination index [ci]<1) and colony formation (clonogenic assay) and induced apoptosis. |
2010-06-14 |
2023-08-12 |
human |
| Gregory Lee, Bixia G. Growth inhibition of tumor cells in vitro by using monoclonal antibodies against gonadotropin-releasing hormone receptor. Cancer immunology, immunotherapy : CII. vol 59. issue 7. 2010-06-02. PMID:20182875. |
growth inhibitions of cancer cells cultured in vitro were demonstrated by cellular apoptosis experiments (tunel and mtt assays) under different conditions of treatment with ghr-106 monoclonal antibody or gnrh analogs. |
2010-06-02 |
2023-08-12 |
human |
| Gregory Lee, Bixia G. Growth inhibition of tumor cells in vitro by using monoclonal antibodies against gonadotropin-releasing hormone receptor. Cancer immunology, immunotherapy : CII. vol 59. issue 7. 2010-06-02. PMID:20182875. |
it was generally observed that both gnrh i and ghr-106 effectively induce the apoptosis of cultured cancer cells as determined by tunel and mtt assays. |
2010-06-02 |
2023-08-12 |
human |
| Hua-Yan Si, Dong-Peng Li, Tian-Ming Wang, Hao-Li Zhang, Fang-Yuan Ren, Zhu-Guo Xu, Yu-Yuan Zha. Improving the anti-tumor effect of genistein with a biocompatible superparamagnetic drug delivery system. Journal of nanoscience and nanotechnology. vol 10. issue 4. 2010-05-26. PMID:20355429. |
the effects of free genistein and feo4-cmch-genistein nano-conjugate on the proliferation and apoptosis of gastric cancer cell line sgc-7901 were investigated by mtt assay and flow cytometry (facs). |
2010-05-26 |
2023-08-12 |
Not clear |
| Tang Xiaojiang, Zhou Jinsong, Wang Jiansheng, Pan Chengen, Yang Guangxiao, Wang Quanyin. Adeno-associated virus harboring fusion gene NT4-ant-shepherdin induce cell death in human lung cancer cells. Cancer investigation. vol 28. issue 5. 2010-05-14. PMID:19968500. |
mtt assay and flow cytometric analysis revealed that raav harboring fusion gene nt4-ant-shepherdin significantly suppressed a549 cell growth in a time-dependent manner and induced apoptosis. |
2010-05-14 |
2023-08-12 |
human |
| Yu Ren, Chun-Sheng Kang, Xu-Bo Yuan, Xuan Zhou, Peng Xu, Lei Han, Guang Xiu Wang, Zhifan Jia, Yue Zhong, Shizhu Yu, Jing Sheng, Pei-Yu P. Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro. Journal of biomaterials science. Polymer edition. vol 21. issue 3. 2010-05-14. PMID:20178687. |
the inhibitory effect toward brain tumors was evaluated by mtt assay, and measurements of cell apoptosis and invasion using the human brain glioma cell line u251. |
2010-05-14 |
2023-08-12 |
human |
| Yan-Ping Zou, Yan-Hua Lu, Dong-Zhi We. Protective effects of a flavonoid-rich extract of Hypericum perforatum L. against hydrogen peroxide-induced apoptosis in PC12 cells. Phytotherapy research : PTR. vol 24 Suppl 1. 2010-05-10. PMID:19548287. |
in the present study, the protective effects of fehp against hydrogen peroxide-induced apoptosis in rat pheochromocytoma line pc12 cells were investigated by mtt assay, lactate dehydrogenase (ldh) release assay, flow cytometry analysis and dna fragmentation assay. |
2010-05-10 |
2023-08-12 |
rat |
| Ying Guo, Jiajia Xu, Nan Li, Feng Gao, Peilin Huan. RegIV potentiates colorectal carcinoma cell migration and invasion via its CRD domain. Cancer genetics and cytogenetics. vol 199. issue 1. 2010-05-04. PMID:20417867. |
cell proliferation was measured by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and flat plate colony-forming assays, and apoptosis was measured by flow cytometry. |
2010-05-04 |
2023-08-12 |
human |
| Cheng-Gang Jiang, Fu-Rong Liu, Miao Yu, Jia-Bin Li, Hui-Mian X. Cimetidine induces apoptosis in gastric cancer cells in vitro and inhibits tumor growth in vivo. Oncology reports. vol 23. issue 3. 2010-04-29. PMID:20127008. |
the mtt assay was used to evaluate cell viability, and flow cytometry, acridine orange staining and transmission electron microscopy were used to detect apoptosis, for cultured cells. |
2010-04-29 |
2023-08-12 |
mouse |
| You Ah Kim, Chang-Suk Kong, Sung Su Yea, Youngwan Se. Constituents of Corydalis heterocarpa and their anti-proliferative effects on human cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 2. 2010-04-21. PMID:20026161. |
the anti-proliferative activity against human cancer cells of compounds 1-6 isolated from c. heterocarpa was evaluated using a mtt assay and by mrna expression of several factors related to apoptosis. |
2010-04-21 |
2023-08-12 |
human |
| Mohammad Lalmoddin Mollah, Jae-Chan Song, Chang-Ho Park, Gee-Dong Lee, Joo-Heon Hong, Zae Young Ryoo, Sanggyu Lee, Kyu-Tae Chang, Kil-Soo Ki. Anticancer activity and apoptotic effects of Bulnesia sarmienti against human lung cancer H460 cells. Oncology research. vol 18. issue 5-6. 2010-04-20. PMID:20225763. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, cell cycle analysis, dna fragmentation, apoptosis, and immunoblot analysis on cells were carried out. |
2010-04-20 |
2023-08-12 |
human |
| Kyle T Keyes, Jing Xu, Bo Long, Congfang Zhang, Zhaoyong Hu, Yumei Y. Pharmacological inhibition of PTEN limits myocardial infarct size and improves left ventricular function postinfarction. American journal of physiology. Heart and circulatory physiology. vol 298. issue 4. 2010-04-12. PMID:20097771. |
as a result, bpv(hopic) decreased cell death, improved 3-[4,5-yl]-2,5-diphenyltetrazolium bromide (mtt) viability, and reduced apoptosis in cells exposed to sir. |
2010-04-12 |
2023-08-12 |
rat |
| Xiao-Sheng Hu, Chang-Qing Du, Lin Yang, Xue-Yan Yao, Shen-Jiang H. Proteasome inhibitor MG132 suppresses number and function of endothelial progenitor cells: involvement of nitric oxide synthase inhibition. International journal of molecular medicine. vol 25. issue 3. 2010-04-12. PMID:20127043. |
after 7 days in culture, epcs were stimulated with proteasome inhibitor mg132 in series of final concentrations of 20, 50, 100, 200 nmol/l for 12, 24, 48 h. cell proliferation and apoptosis were determined, respectively, by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, annexin v/propidium iodide binding assay. |
2010-04-12 |
2023-08-12 |
Not clear |
| Xihai Li, Min Du, Xianxiang Liu, Mingxia Wu, Hongzhi Ye, Jiumao Lin, Wenlie Chen, Guangwen W. Millimeter wave treatment inhibits NO-induced apoptosis of chondrocytes through the p38MAPK pathway. International journal of molecular medicine. vol 25. issue 3. 2010-04-12. PMID:20127044. |
the apoptosis of chondrocytes was detected using immunofluorescence, an mtt assay, and annexin v-fitc labeling followed by fluorescence-activated cell sorting (facs). |
2010-04-12 |
2023-08-12 |
rat |
| Boglarka Racz, Gabriella Horvath, Dora Reglodi, Balazs Gasz, Peter Kiss, Ferenc Gallyas, Balazs Sumegi, Gabor Toth, Adrienne Nemeth, Andrea Lubics, Andrea Tama. PACAP ameliorates oxidative stress in the chicken inner ear: an in vitro study. Regulatory peptides. vol 160. issue 1-3. 2010-04-09. PMID:19969027. |
chicken cochlear cells were exposed to 1mm h(2)o(2), which resulted in a marked reduction of cell viability and a parallel increase of apoptotic and necrotic cells assessed by mtt test, annexin v/propidium iodide flow cytometry and jc-1 apoptosis assay. |
2010-04-09 |
2023-08-12 |
chicken |
| Shihui Li, Fang Xue, Zhiyong Cheng, Xiaoyang Yang, Suyun Wang, Fengyong Geng, Ling Pa. Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NFkappaB p65. International journal of hematology. vol 90. issue 4. 2010-04-08. PMID:19728025. |
the growth inhibition of sp2/0 cell proliferation induced by artesunate (art) treatment was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) method and the rate of apoptosis and cell cycle changes induced by art were analyzed by flow cytometry. |
2010-04-08 |
2023-08-12 |
mouse |
| Chao Tang, Hong-li Xue, Hai-bo Huang, Xiao-gang Wan. Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells. Neuroscience letters. vol 470. issue 2. 2010-04-06. PMID:20045721. |
cell growth and proliferation were measured by mtt assay, cell apoptosis was observed by flow cytometry and dna-fragmentation analysis. |
2010-04-06 |
2023-08-12 |
rat |
| Yin-Gang Zhang, Zhi Yang, Hong Zhang, Cunrong Wang, Miao Liu, Xiong Guo, Peng X. Effect of negative pressure on human bone marrow mesenchymal stem cells in vitro. Connective tissue research. vol 51. issue 1. 2010-04-06. PMID:20067412. |
the mtt assay and flow cytometry were used to measure proliferation and apoptosis. |
2010-04-06 |
2023-08-12 |
human |
| Sujeong Jang, Han-Seong Jeong, Jong-Seong Park, Yeong-Seon Kim, Chun-Yan Jin, Myung Bok Seol, Byeong-Chae Kim, Min-Cheol Le. Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition. Brain research. vol 1313. 2010-04-05. PMID:20025854. |
the cells were pretreated with egcg for 2 h and then exposed to quinolinic acid (quin), a nmda receptor agonist, 30 mm for 24 h. mtt assay and dapi staining were used to identify cell viability and apoptosis, respectively, and demonstrated that egcg significantly increased cell viability and protected the cells from apoptotic death. |
2010-04-05 |
2023-08-12 |
Not clear |
| Saijun Fan, Qinghui Meng, John J Laterra, Eliot M Rose. Scatter factor protects tumor cells against apoptosis caused by TRAIL. Anti-cancer drugs. vol 21. issue 1. 2010-04-02. PMID:19823077. |
we used mtt assays, trypan blue dye exclusion assays, apoptosis assays, rna interference, luciferase reporter assays, immunoprecipitation/western blotting, and other cell biological techniques to study sf protection of cultured human tumor cells against trail. |
2010-04-02 |
2023-08-12 |
human |