| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liang Zhang, Ji Li, ZhenZhou Jiang, LiXin Sun, Xue Mei, Bian Yong, LuYong Zhan. Inhibition of aquaporin-1 expression by RNAi protects against aristolochic acid I-induced apoptosis in human proximal tubular epithelial (HK-2) cells. Biochemical and biophysical research communications. vol 405. issue 1. 2011-03-14. PMID:21215257. |
apoptosis was studied by different methods, including 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (mtt) assays, flow cytometry, and caspase 3 activity assays. |
2011-03-14 |
2023-08-12 |
human |
| Tui Neri, Monica Bucciantini, Vittorio Rosti, Sara Raimondi, Annalisa Relini, Margherita Massa, Maurizio Zuccotti, Simona Donadei, Massimo Stefani, Carlo Alberto Redi, Giampaolo Merlini, Monica Stoppini, Silvia Garagna, Vittorio Bellott. Embryonic stem and haematopoietic progenitor cells resist to Aβ oligomer toxicity and maintain the differentiation potency in culture. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 17. issue 3-4. 2011-03-10. PMID:21067308. |
these stem cells did not display any sign of apoptosis and their survival, proliferation and differentiation were not affected by the oligomers although the mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay revealed that es, but not hp, cells displayed some impaired ability to reduce the tetrazole salts possibly as a result of transient oxidative stress. |
2011-03-10 |
2023-08-12 |
Not clear |
| Anning Yin, Yingan Jiang, Xianfeng Zhang, Juan Zhao, Hesheng Lu. Transfection of PDCD5 sensitizes colorectal cancer cells to cisplatin-induced apoptosis in vitro and in vivo. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20869960. |
the effects of cisplatin in combination with pdcd5 on the proliferation and apoptosis of colorectal cancer cells were measured by using mtt analysis, hoechst 33258 analysis and flow cytometry with annexin-v-fitc/pi dual labeling, respectively. |
2011-03-03 |
2023-08-12 |
mouse |
| A S Azmi, P A Philip, F W J Beck, Z Wang, S Banerjee, S Wang, D Yang, F H Sarkar, R M Mohamma. MI-219-zinc combination: a new paradigm in MDM2 inhibitor-based therapy. Oncogene. vol 30. issue 1. 2011-02-28. PMID:20818437. |
zncl(2) enhanced mi-219 activity (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), apoptosis and colony formation), and chelation of zinc not only blocked the activity of mi-219, but also suppressed reactivation of the p53 and its downstream effector molecules p21(waf1) and bax. |
2011-02-28 |
2023-08-12 |
Not clear |
| Liming Shen, Ziyao Lan, Xiaohong Sun, Lei Shi, Qiong Liu, Jiazuan N. Proteomic analysis of lanthanum citrate-induced apoptosis in human cervical carcinoma SiHa cells. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 23. issue 6. 2011-02-24. PMID:20814718. |
cell growth inhibition was measured by mtt method, and apoptosis was detected by means of hoechst 33258 staining and flow cytometry analysis. |
2011-02-24 |
2023-08-12 |
human |
| Shengbao Li, Dean Tian, Pei Fei, Yuanjun Gao, Zihua Chen, Qiang Wang, Qiang Ton. A cyclooxygase-2 inhibitor NS-398-enhanced apoptosis of esophageal carcinoma cell EC9706 by adjusting expression of survivin and caspase-3. Cancer investigation. vol 29. issue 2. 2011-02-24. PMID:21329005. |
after the treatment with ns-398 on esophageal carcinoma ec9706 cell, mtt assay was used to observe the inhibition of ec9706 cell growth and apoptosis was determined by electronic microscopy and flow cytometry. |
2011-02-24 |
2023-08-12 |
Not clear |
| Sarah Jones, John How. Applications of cell-penetrating peptides as signal transduction modulators for the selective induction of apoptosis. Methods in molecular biology (Clifton, N.J.). vol 683. 2011-02-15. PMID:21053138. |
this chapter, therefore, focuses on methodologies for the assessment of apoptotic events, including in situ tunel analysis, activation of caspase-3, and the mtt assay, whilst also discussing dual annexin v and propidium iodide staining, an assay used for the quantification of cell populations undergoing apoptosis and/or necrosis. |
2011-02-15 |
2023-08-12 |
Not clear |
| Bin Qu, Wei Wang, Zhenyi Tan, Di Li, Jun Wan, Jie Sun, Kun Cheng, Hao Lu. Diethyl (6-amino-9H-purin-9-yl) methylphosphonate induces apoptosis and cell cycle arrest in hepatocellular carcinoma BEL-7402 cells: Role of reactive oxygen species. Free radical research. vol 44. issue 8. 2011-02-14. PMID:20528564. |
using cell survival mtt assay, flow cytometry analysis, dna laddering, dcf fluorescence detection and caspases assays, this study investigated the effects of this compound on cell apoptosis, cell cycle regulation and reactive oxygen species in human hepatocarcinoma bel-7402 cell lines. |
2011-02-14 |
2023-08-12 |
human |
| Ning Jiang, Li-Qun Zhou, Xiao-Yu Zhan. Downregulation of the nucleosome-binding protein 1 (NSBP1) gene can inhibit the in vitro and in vivo proliferation of prostate cancer cells. Asian journal of andrology. vol 12. issue 5. 2011-02-07. PMID:20531280. |
after nsbp1 knockdown in du145 cells, the growth rate of cells was analyzed by mtt, and g(2)/m cell cycle arrest and apoptosis were assessed using a facscalibur flow cytometer. |
2011-02-07 |
2023-08-12 |
mouse |
| Tzuu-Yuan Huang, Tai-Hsin Tsai, Che-Wen Hsu, Yi-Chiang Hs. Curcuminoids suppress the growth and induce apoptosis through caspase-3-dependent pathways in glioblastoma multiforme (GBM) 8401 cells. Journal of agricultural and food chemistry. vol 58. issue 19. 2011-02-03. PMID:20822178. |
results indicated that curcuminoids have produced an inhibition of cell proliferation in a dose-dependent manner as dosage increased from 12.5 to 100 μm (n = 6) via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay as well as activation of apoptosis in gbm 8401 cells. |
2011-02-03 |
2023-08-12 |
human |
| Di Wu, Wentao Zhang, Qingying Luo, Kan Luo, Liqin Huang, Wenxi Wang, Tao Huang, Rui Chen, Yi Lin, Daiwen Pang, Gengfu Xia. Copper (II) promotes the formation of soluble neurotoxic PrP oligomers in acidic environment. Journal of cellular biochemistry. vol 111. issue 3. 2011-01-31. PMID:20564047. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and flow cytometry assays demonstrated that oligomeric prp induced significant damage in and apoptosis of neuroblastoma sk-n-sh cells. |
2011-01-31 |
2023-08-12 |
Not clear |
| Neekkan Dey, Archita Das, Arunava Ghosh, Indu B Chatterje. Activated charcoal filter effectively reduces p-benzosemiquinone from the mainstream cigarette smoke and prevents emphysema. Journal of biosciences. vol 35. issue 2. 2011-01-31. PMID:20689178. |
the charcoal filter also prevented cytotoxicity in a549 cells as evidenced by mtt assay, apoptosis as evidenced by facs analysis, tunel assay, overexpression of bax, activation of p53 and caspase 3, as well as emphysematous lung damage in a guinea pig model as seen by histology and morphometric analysis. |
2011-01-31 |
2023-08-12 |
cattle |
| Sahng-Wook Hahm, Jieun Park, Yong-Suk So. Opuntia humifusa partitioned extracts inhibit the growth of U87MG human glioblastoma cells. Plant foods for human nutrition (Dordrecht, Netherlands). vol 65. issue 3. 2011-01-31. PMID:20814744. |
glioblastoma cellular proliferation was evaluated using the mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, and the effects of o. humifusa partitioned extracts on cell cycle and apoptosis were analyzed by flow cytometry. |
2011-01-31 |
2023-08-12 |
human |
| R Senthil Murugan, R Vidya Priyadarsini, K Ramalingam, Y Hara, D Karunagaran, S Nagin. Intrinsic apoptosis and NF-κB signaling are potential molecular targets for chemoprevention by black tea polyphenols in HepG2 cells in vitro and in a rat hepatocarcinogenesis model in vivo. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 11. 2011-01-25. PMID:20828598. |
viability of hepg2 cells was evaluated by the mtt assay, and apoptosis by ao-eb and dapi staining, cell cycle analysis, and annexin v-pi assay. |
2011-01-25 |
2023-08-12 |
rat |
| Xiaoqi He, Ying Qian, Huilan Cai, Zehua Wan. The effect of RhoC siRNA on the invasiveness and proliferation of human cervical cancer cell line SiHa cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 28. issue 6. 2011-01-21. PMID:19107362. |
the proliferation and apoptosis of siha cells were examined by mtt assay and flow cytometry (facs), respectively. |
2011-01-21 |
2023-08-12 |
human |
| Cheol Park, Cheng-Yun Jin, Gi-Young Kim, JaeHun Cheong, Jee H Jung, Young Hyun Yoo, Yung Hyun Cho. A methyl jasmonate derivative, J-7, induces apoptosis in human hepatocarcinoma Hep3B cells in vitro. Toxicology in vitro : an international journal published in association with BIBRA. vol 24. issue 7. 2011-01-18. PMID:20696234. |
treatment of hep3b cells with j-7 resulted in growth inhibition and the induction of apoptosis as measured by trypan blue-excluding cells, mtt assay, nuclear staining, dna fragmentation, and flow cytometry analysis. |
2011-01-18 |
2023-08-12 |
human |
| Kyoji Hagiwara, Tomoyuki Murakami, Guangai Xue, Yasuo Shimizu, Eri Takeda, Yoshie Hashimoto, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Yasuko Tsunetsugu-Yokota, Yoko Aid. Identification of a novel Vpr-binding compound that inhibits HIV-1 multiplication in macrophages by chemical array. Biochemical and biophysical research communications. vol 403. issue 1. 2011-01-13. PMID:21036153. |
sip-1 had no cytotoxic effects and did not disrupt cell cycle progression or induce apoptosis of molt-4 and hela cell lines as measured by mtt assay, flow-cytometry analysis, and a caspase-3 assay. |
2011-01-13 |
2023-08-12 |
Not clear |
| Qi-Hong Zhao, Ying Zhang, Yun Liu, Hui-Li Wang, Yuan-Yuan Shen, Wen-Jun Yang, Long-Ping We. Anticancer effect of realgar nanoparticles on mouse melanoma skin cancer in vivo via transdermal drug delivery. Medical oncology (Northwood, London, England). vol 27. issue 2. 2011-01-12. PMID:19280372. |
in this study, mtt assay and flow cytometry analysis demonstrated that realgar significantly suppressed the proliferation and induced apoptosis of b16 melanoma cells in a dose-dependent manner. |
2011-01-12 |
2023-08-12 |
mouse |
| Shuanglin Xiang, Zhenhua Sun, Qiongzhi He, Feng Yan, Yijun Wang, Jian Zhan. Aspirin inhibits ErbB2 to induce apoptosis in cervical cancer cells. Medical oncology (Northwood, London, England). vol 27. issue 2. 2011-01-12. PMID:19424877. |
to investigate the effects of aspirin on apoptosis and proliferation, we tested apoptosis by hoechst 33258 staining and annexin v-fitc/pi method; mtt assay and colony formation assay were used to detect proliferation. |
2011-01-12 |
2023-08-12 |
Not clear |
| Yu Zhao, Lujing Zhao, Lijia Zhou, Yuan Zhi, Jianming Xu, Zheng Wei, Kelvin Xi Zhang, B F Francis Ouellette, Hebai She. Quantum dot conjugates for targeted silencing of bcr/abl gene by RNA interference in human myelogenous leukemia K562 cells. Journal of nanoscience and nanotechnology. vol 10. issue 8. 2011-01-11. PMID:21125862. |
cell proliferation was examined by the mtt assay and cell apoptosis by facs. |
2011-01-11 |
2023-08-12 |
human |