| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian-Min Luo, Yan Li, Lin Yang, Xiao-Jun Liu, Shu-Peng Wen, Fu-Xu Wang, Jing-Yu Zhang, Xue-Jun Zhang, Zuo-Ren Don. [Effect of a methylation inhibitor 5-aza-2'-deoxycytidine on SHP-1 gene expression, proliferation and apoptosis in K562 cells]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379557. |
mtt and flow cytometry were used to detect the growth and apoptosis of k562 cells after treatment with different concentration of 5-aza-cdr. |
2011-07-12 |
2023-08-12 |
Not clear |
| Ting-Bo Liu, Shu-Biao Zou, Zhi-Zhe Che. [Apoptosis of human myeloid leukemia cell line HL-60 cells induced by siRNA targeting gene c-myc]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379561. |
growth inhibition was detected by mtt assay and colony formation assay, and cell apoptosis was determined by dna ladder. |
2011-07-12 |
2023-08-12 |
human |
| Jia-Jia Shi, Xiao-Hui Jia, Xiao-Hong Li, Zhi-Yong Cheng, Xiao-Xuan Wei, Li-Hong Sun, Ze-Lin Li. [Effect of rapamycin on proliferation, apoptosis and regulation of chemokine receptor CXCR4 in RPMI8226 cells]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379572. |
the proliferation of the cells was detected by mtt assay; the apoptosis rate and cell cycle were determined by flow cytometry (fcm); apoptosis of cells was observed by inverted microscopy; the cylin d1, cxcr4 and mtor mrna expressions were detected by rt-pcr or fq-pcr after treating rpmi8226 cells with different concentrations of rapamycin. |
2011-07-12 |
2023-08-12 |
Not clear |
| Rui Xu, Kenji Nakano, Hironori Iwasaki, Michiaki Kumagai, Rie Wakabayashi, Akio Yamasaki, Hiroyuki Suzuki, Ryuichi Mibu, Hideya Onishi, Mitsuo Katan. Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer. Cancer letters. vol 306. issue 2. 2011-07-12. PMID:21429662. |
cell viability and apoptosis were determined by mtt assay, cell cycle analysis in flow cytometer and hoechst nuclear staining. |
2011-07-12 |
2023-08-12 |
Not clear |
| Bao-An Chen, Qing-Qi Meng, Wei Wu, Feng Gao, Ze-Ye Shao, Jia-Hua Ding, Chong Gao, Xin-Chen Sun, Hong-Yan Cheng, Yun-Yu Sun, Jun Wang, Jian Cheng, Gang Zhao, Hui-Hui Song, Wen Bao, Yan Ma, Xue-Mei Wan. [Enhancement of reversing drug resistance of K562/A02 cells to adriamycin by ultrasound-induced cavitation]. Zhongguo shi yan xue ye xue za zhi. vol 16. issue 6. 2011-07-08. PMID:19099628. |
the trypan blue dye exclusion test and mtt assay were used to determine the cell viability; wright's staining was used to detect the apoptosis; the flow cytometry was used to analyze the drug concentration, and the scanning electron microscopy was used to observe the changes of cell surface. |
2011-07-08 |
2023-08-12 |
Not clear |
| Jun Lu, Shi Yuan Xu, Qing Guo Zhang, Rui Xu, Hong Yi Le. Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. European journal of pharmacology. vol 657. issue 1-3. 2011-07-06. PMID:21315711. |
the cell viability, mitochondrial membrane potential, phospho-p38 mapk (p-p38 mapk) and cell apoptosis were investigated with mtt assay, western blots, hoechst 33258 staining and flow cytometry assay. |
2011-07-06 |
2023-08-12 |
Not clear |
| M Zhong, D H Carney, H Jo, B D Boyan, Z Schwart. Inorganic phosphate induces mammalian growth plate chondrocyte apoptosis in a mitochondrial pathway involving nitric oxide and JNK MAP kinase. Calcified tissue international. vol 88. issue 2. 2011-06-22. PMID:21104071. |
pi decreased the number of viable cells based on mtt activity; the number of tunel-positive cells and the level of dna fragmentation were increased, indicating an increase in apoptosis. |
2011-06-22 |
2023-08-12 |
mouse |
| Zhiwei Chen, Xiaomin Niu, Ziming Li, Yongfeng Yu, Xiangyun Ye, Shun Lu, Zhen Che. Effect of ubiquitin carboxy-terminal hydrolase 37 on apoptotic in A549 cells. Cell biochemistry and function. vol 29. issue 2. 2011-06-20. PMID:21287580. |
using mtt assay, western blot, hoechst 33342 staining assay and flow cytometry, we found that silencing of uch37 in a549 cells induced apoptosis. |
2011-06-20 |
2023-08-12 |
Not clear |
| Ying Xiang, Qiang Li, Menglan Li, Wei Wang, Can Cui, Jinchao Zhan. Ghrelin inhibits AGEs-induced apoptosis in human endothelial cells involving ERK1/2 and PI3K/Akt pathways. Cell biochemistry and function. vol 29. issue 2. 2011-06-20. PMID:21370247. |
exposure to ages (200 mg l(-1) ) for 48 h caused a significant increase in cell apoptosis, while pretreatment with ghrelin eliminated ages-induced apoptosis in huvecs, as evaluated by mtt assays, flow cytometry and hoechst 33258 staining. |
2011-06-20 |
2023-08-12 |
human |
| Seung-Hwan Kwon, Ji-Ah Kim, Sa-Ik Hong, Yang-Hee Jung, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jan. Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells. Neurochemistry international. vol 58. issue 4. 2011-06-17. PMID:21241762. |
the neuroprotective effect of loganin was investigated by treating sh-sy5y cells with h(2)o(2) and then measuring the reduction in h(2)o(2)-induced apoptosis using 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) and lactate dehydrogenase (ldh) release assays. |
2011-06-17 |
2023-08-12 |
Not clear |
| Shiau-Chuen Cheah, David R Appleton, Sui-Ting Lee, May-Lynn Lam, A Hamid A Hadi, Mohd Rais Mustaf. Panduratin A inhibits the growth of A549 cells through induction of apoptosis and inhibition of NF-kappaB translocation. Molecules (Basel, Switzerland). vol 16. issue 3. 2011-06-16. PMID:21441862. |
cell proliferation and induction of apoptosis was determined by the real-time cellular analyzer (rtca), mtt assay and high content screening (hcs). |
2011-06-16 |
2023-08-12 |
human |
| Kasi Viswanath, Sreedhar Bodiga, Victor Balogun, Anita Zhang, Vijaya Lakshmi Bodig. Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 24. issue 1. 2011-06-14. PMID:20809125. |
neonatal rat cardiac myocytes subjected to 8 h of hypoxia, followed by 16 h of reoxygenation induced cardiomyocyte apoptosis, as assessed by increased caspase-3 activity, annexin v staining and lowered mtt reduction and atp levels. |
2011-06-14 |
2023-08-12 |
rat |
| Zhenya Hong, Zhiqiang Han, Min Xiao, Yang Yang, Xi Xia, Jianfeng Zho. Microarray study of mechanism of trichostatin a inducing apoptosis of Molt-4 cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 4. 2011-06-06. PMID:19662360. |
flow cytometry, mtt and dna ladder were used to observe the effect of tsa on the apoptosis of molt-4 cells and normal human peripheral blood mononuclear cells (pbmc). |
2011-06-06 |
2023-08-12 |
human |
| H Y Jang, S J Ji, Y H Kim, H Y Lee, J S Shin, H T Cheong, J T Kim, I C Park, H S Kong, C K Park, B K Yan. Antioxidative effects of astaxanthin against nitric oxide-induced oxidative stress on cell viability and gene expression in bovine oviduct epithelial cell and the developmental competence of bovine IVM/IVF embryos. Reproduction in domestic animals = Zuchthygiene. vol 45. issue 6. 2011-06-02. PMID:19930137. |
we examined the effects of astaxanthin against nitric oxide-induced oxidative stress on cell viability by mtt assay, lipid peroxidation (lpo) by using thiobarbituric acid (tba) reaction for malondialdehyde (mda) and the expression of antioxidant genes (cuznsod, mnsod and catalase) or apoptosis genes (bcl-2, caspase-3 and bax) by rt-pcr in boec. |
2011-06-02 |
2023-08-12 |
cattle |
| Yuan Wang, Chuner Cai, Bailin Li, Chengchu Liu, Peimin H. [Photodynamic effect of two kinds of phycobiliproteins on human liver cancer cell line SMMC-7721 in vitro]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 25. issue 9. 2011-05-31. PMID:19938487. |
with 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay (mtt assay), we used two phycobiliproteins, r-phycoerythrin (r-pe) and c-phycocyanin (c-pc) prepared from porphyra yezoensis, to determine the killing rates and apoptosis rates of human liver cancer cells (smmc-7721) mediated by laser. |
2011-05-31 |
2023-08-12 |
human |
| Yali Han, Jingcheng Miao, Weihua Sheng, Xiaohua Wang, Yingying Jing, Yunbo Shan, Tielian Liu, Wanrong Bao, Jicheng Yan. [Interleukin 24 inhibits growth and induces apoptosis of osteosarcoma cells MG-63 in vitro and in vivo]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 25. issue 10. 2011-05-31. PMID:20112699. |
the expression level of il-24 was detected by rt-pcr and fluorescence microscope; the growth inhibition, apoptosis rate and apoptosis body were measured by mtt, flow cytometry and hoechst staining respectively. |
2011-05-31 |
2023-08-12 |
mouse |
| Shun-Lai Li, Chia-Hsin Huang, Chih-Chan Lin, Zih-Ning Huang, Jyh-Haur Chern, Hsiao-Yin Lien, Yong-Yi Wu, Chia-Hui Cheng, Chia-Yu Chang, Jiunn-Jye Chu. Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer. Investigational new drugs. vol 29. issue 2. 2011-05-27. PMID:19960226. |
our results showed that bpr-dc-2 significantly inhibited proliferation of tumor cells with an ic50 of 3.60 ± 1.27 and 14.81 ± 4.23 μm in human lung carcinoma cells, h69 and a549, respectively by the mtt assay at 48 hr; bpr-dc-2 also obviously suppressed the tumor proliferation and mdr-1 gene expression, even induced cell apoptosis in the ex vivo histocultured lung tumor. |
2011-05-27 |
2023-08-12 |
mouse |
| Zhi-Hua Liu, Yan-Lei Ma, Yan-Ping He, Peng Zhang, Yu-Kun Zhou, Huanlong Qi. Tamoxifen reverses the multi-drug-resistance of an established human cholangiocarcinoma cell line in combined chemotherapeutics. Molecular biology reports. vol 38. issue 3. 2011-05-23. PMID:20835928. |
cell growth inhibition was determined by the mtt assay, while cell cycle progression, apoptosis and the intra-cellular concentration of adriamycin (adm) were all determined by flow cytometry. |
2011-05-23 |
2023-08-12 |
human |
| Yanyan Xu, Qi Zhang, Shu Yu, Yumin Yang, Fei Din. The protective effects of chitooligosaccharides against glucose deprivation-induced cell apoptosis in cultured cortical neurons through activation of PI3K/Akt and MEK/ERK1/2 pathways. Brain research. vol 1375. 2011-05-23. PMID:21167818. |
the cell viability assessment by mtt assay, in couple with cell apoptosis analysis by hoechst 33342 and tunel staining, indicated that gd-induced cell apoptosis in cultured cortical neurons was attenuated by coss co-treatment in a dose-dependent manner. |
2011-05-23 |
2023-08-12 |
Not clear |
| Chun-jing Zhang, Li-gang Gu, Hai-tao Y. [Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus]. Bing du xue bao = Chinese journal of virology. vol 27. issue 2. 2011-05-20. PMID:21528534. |
to observe the inhibitive effect of baicalin against influenza a h1n1 virus infection in epithelial cell line a549, the cell proliferation and cytotoxicity were assayed by mtt, the cell cycle and the apoptosis were analyzed by flowcytometer using pi staining, the morphology of cellular nucleolus was observed by hoechst 33258 staining and the effects of activation on caspase 3 and caspase 8/9 were also detected by immunofluorescent staining with a fluorescence microscope. |
2011-05-20 |
2023-08-12 |
Not clear |