| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehrdad Hashemi, Mehdi Nouri Long, Maliheh Entezari, Shohreh Nafisi, Hossein Nowroozi. Anti-mutagenic and pro-apoptotic effects of apigenin on human chronic lymphocytic leukemia cells. Acta medica Iranica. vol 48. issue 5. 2011-07-25. PMID:21287458. |
during mtt assay, human chronic lymphocytic leukemia revealed to have a meaningful cell death when compared with controls (p<0.01) apoptosis was induced suitably after 48 hours by flow cytometry assay. |
2011-07-25 |
2023-08-12 |
human |
| Niloufar Ansari, Fariba Khodagholi, Mohsen Amin. 2-Ethoxy-4,5-diphenyl-1,3-oxazine-6-one activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death. European journal of pharmacology. vol 658. issue 2-3. 2011-07-25. PMID:21371450. |
we found that h(2)o(2) triggered a range of cellular cascades which leads to cell death, whereas pretreatment of the cells with this oxazine derivative attenuated the extent of apoptosis, as assessed by mtt assay, acridine orange/ethidium bromide staining and caspase-3 expression assay. |
2011-07-25 |
2023-08-12 |
rat |
| Zhao Lifeng, Hong Yan, Yang Dayun, Lü Xiaoying, Xi Tingfei, Zhang Deyuan, Hong Ying, Yuan Jinfen. The underlying biological mechanisms of biocompatibility differences between bare and TiN-coated NiTi alloys. Biomedical materials (Bristol, England). vol 6. issue 2. 2011-07-22. PMID:21441653. |
in this study, to explore the underlying biological mechanisms of biocompatibility differences between them, the changes of bare and tin-coated niti alloys in surface chemical composition, morphology, hydrophilicity, ni ions release, cytotoxicity, apoptosis, and gene expression profiles were compared using energy-dispersive spectroscopy, scanning electron microscopy, contact angle, surface energy, ni ions release analysis, the methylthiazoltetrazolium (mtt) method, flow cytometry and microarray methods, respectively. |
2011-07-22 |
2023-08-12 |
Not clear |
| Alice Xu, Colette Prophete, Lung-chi Chen, Charles W Emala, Mitchell D Cohe. Interactive effect of cigarette smoke extract and world trade center dust particles on airway cell cytotoxicity. Journal of toxicology and environmental health. Part A. vol 74. issue 14. 2011-07-22. PMID:21623534. |
human cultured airway epithelial (beas-2b) cells were exposed to 10% cigarette smoke extract (cse), wtc dust particles (10-53 μm; 0.01-0.5 μg/μl), or a combination of the two for 2-24 h. cell viability was measured by determining mitochondrial integrity (mtt assays) and apoptosis (poly-adp-ribose polymerase [parp] immunoblotting). |
2011-07-22 |
2023-08-12 |
human |
| Qin Li, Dong Liu, Xianju Huang, Lianjun Gu. Fasudil mesylate protects PC12 cells from oxidative stress injury via the Bax-mediated pathway. Cellular and molecular neurobiology. vol 31. issue 2. 2011-07-18. PMID:21061151. |
pretreatment with fm (5, 10 μm) prior to h(2)o(2) exposure significantly elevated cell viability, reduced cell apoptosis by mtt assay, ldh assay, hoechst 33258 dye staining, and fm also decreased the accumulation of reactive oxygen species (ros) by dcfh-da staining and nbt test. |
2011-07-18 |
2023-08-12 |
rat |
| Yanjing Yang, Huidan Yan, Yuqin Li, Shang-Tian Yang, Xuewu Zhan. Isothiocyanates from Broccolini seeds induce apoptosis in human colon cancer cells: proteomic and bioinformatic analyses. Die Pharmazie. vol 66. issue 5. 2011-07-18. PMID:21699074. |
we found that itcs induces sw480 cells apoptosis in a dose-dependent manner by using mtt assay, phase contrast microscope and flow cytometry, and the ic50 was calculated to be 77.72 microg/ml, superior to the chemotherapeutical drug 5-flurouracil. |
2011-07-18 |
2023-08-12 |
human |
| Wang Qian-hua, Zhong Shao-ping, Zhu Jian-wen, Yang Yun, Zou L. Reduced expression of netrin-1 is associated with fetal growth restriction. Molecular and cellular biochemistry. vol 350. issue 1-2. 2011-07-15. PMID:21193949. |
human placental microvascular endothelial cells were isolated and, after treatment with netrin-1, examined for their viability and apoptosis by using mtt assay and flow cytometry. |
2011-07-15 |
2023-08-12 |
human |
| Jun-Feng Zhang, Jia-Jun Liu, Pei-Qing Liu, Dong-Jun Lin, Xu-Dong Li, Gui-Hua Che. Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL-7402 cells. Hepatology research : the official journal of the Japan Society of Hepatology. vol 35. issue 2. 2011-07-14. PMID:16638644. |
cell proliferation was measured by mtt assay and [(3)h]-thymidine uptake, cell apoptotic rate was detected by flow cytometry (fcm), morphology of cell apoptosis was observed by hoechst 33258 staining and dna fragmentation. |
2011-07-14 |
2023-08-12 |
human |
| Yingsong Xiang, Gusheng Tang, Xiongfei Xu, Rujun Yang, Jianming Cai, Minghui Zhang, Xuetao Ca. Effects of anesthesia-induced modest hypothermia on cellular radiation sensitivity. Science in China. Series C, Life sciences. vol 45. issue 1. 2011-07-14. PMID:18763066. |
both apoptosis and necrosis of human fetal bone marrow cd34(+) hematopoietic stem cells cultured under mh were significantly decreased as detected by mtt and flow cytometry, with three-color labeled by pe-cd(34) (+)/ fitc-annexinv /7aad. |
2011-07-14 |
2023-08-12 |
mouse |
| Ping Liu, Lei Zhao, Shu-Ling Zhang, Ji-Zhou Xian. Modified Wendan Decoction can Attenuate Neurotoxic Action Associated with Alzheimer's Disease. Evidence-based complementary and alternative medicine : eCAM. vol 6. issue 3. 2011-07-14. PMID:18955245. |
cell mortality and survival rate was examined by trypan blue stain assay and mtt method and caspase-3 expression was detected by western blot, while cell apoptosis was examined by flow cytometry. |
2011-07-14 |
2023-08-12 |
rat |
| Hak-Jae Kim, Jeong Yoon Song, Hae Jeong Park, Hyun-Kyung Park, Dong Hwan Yun, Joo-Ho Chun. Naringin Protects against Rotenone-induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 13. issue 4. 2011-07-14. PMID:19885011. |
we assessed cell death and apoptosis by measuring mitogen-activated protein kinase (mapks) and caspase (casps) activities and by performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, 4,6-diamidino-2-phenylindole (dapi) staining, and terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) staining. |
2011-07-14 |
2023-08-12 |
human |
| Ke Tang, Zhongtao Zhang, Zhigang Bai, Xuemei Ma, Wei Guo, Yu Wan. Enhancement of gemcitabine sensitivity in pancreatic cancer by co-regulation of dCK and p8 expression. Oncology reports. vol 25. issue 4. 2011-07-14. PMID:21225236. |
using mtt assays, we observed that combined infection using ad-dck and ad-p8-sirna in vitro led to a significant decrease in the gemcitabine ic50 with an increase in apoptosis and caspase-3 activity in panc-1 cells, which are relatively resistant to gemcitabine. |
2011-07-14 |
2023-08-12 |
mouse |
| Siddig Ibrahim Abdelwahab, Syam Mohan, Manal Mohamed Elhassan, Nabil Al-Mekhlafi, Abdelbasit Adam Mariod, Ahmad Bustamam Abdul, Mahmood Ameen Abdulla, Khalid M Alkharf. Antiapoptotic and Antioxidant Properties of Orthosiphon stamineus Benth (Cat's Whiskers): Intervention in the Bcl-2-Mediated Apoptotic Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2011. 2011-07-14. PMID:21234328. |
the role of os against hydrogen peroxide induced apoptosis on mda-m231 epithelial cells was examined using mtt assay, phase contrast microscope, colorimetric assay of caspase-3, western blot and quantitative real-time pcr. |
2011-07-14 |
2023-08-12 |
cat |
| Maria Notarnicola, Simona Pisanti, Valeria Tutino, Domenica Bocale, Maria Teresa Rotelli, Antonio Gentile, Vincenzo Memeo, Maurizio Bifulco, Enzo Perri, Maria Gabriella Carus. Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells. Genes & nutrition. vol 6. issue 1. 2011-07-14. PMID:21437031. |
cell growth and apoptosis, after polyphenols treatment, were measured by mtt test and flow cytometry, respectively. |
2011-07-14 |
2023-08-12 |
human |
| Hong-Rui Yao, Jun Liu, Daniel Plumeri, Yong-Bing Cao, Ting He, Ling Lin, Yu Li, Yuan-Ying Jiang, Ji Li, Jing Shan. Lipotoxicity in HepG2 cells triggered by free fatty acids. American journal of translational research. vol 3. issue 3. 2011-07-14. PMID:21654881. |
the data collected from hoechst 33342/pi, annexin v-fitc/pi double staining and also mtt experiments showed that cell apoptosis and necrosis significantly increased with increasing ffa concentrations. |
2011-07-14 |
2023-08-12 |
Not clear |
| Shu-Yan Wang, Chao-Hui Sun, Min Wei, Wen-Li M. [Signal pathway in apoptosis of K562 cells induced by STI571]. Zhongguo shi yan xue ye xue za zhi. vol 16. issue 5. 2011-07-12. PMID:18928585. |
the gene microarray probes were prepared by rd-pcr technique, then the microarray of gene expression map was constructed; the morphologic changes of k562 cells were observed under phase-contrast microscopy before and after treatment with sti571; the apoptosis of k562 cells treated with sti571 was assayed by mtt method; the expression level of genes was analyzed by self-made microarray. |
2011-07-12 |
2023-08-12 |
Not clear |
| Qi-Tian Mu, Gui-Fang Ouyang, Yan-Ru Lou, Xiao-Pei Chen, Ying Lu, Wei Liang, Yi Zhang, Wei X. [Inducing-apoptosis effect of bortezomib on acute monocytic leukemia cell SHI-1 and its influence on expressions of Bcl2l12, Bcl-2 and Bax genes]. Zhongguo shi yan xue ye xue za zhi. vol 16. issue 5. 2011-07-12. PMID:18928586. |
mtt assay was used to detect the proliferation and apoptosis, annexin-v staining, mitochondrial transmembrane potential (deltapsim) and dna aga-rose gel electrophoresis were used to investigate apoptosis of shi-1 cells. |
2011-07-12 |
2023-08-12 |
Not clear |
| Xi-Hui Xu, Jian Ouyang, Pin-Hao Xie, Jun-Hao Che. [Changes of activity and expression of protein phosphatase type 2A during the apoptosis of NB4 and MR2 cells induced by arsenic trioxide]. Zhongguo shi yan xue ye xue za zhi. vol 16. issue 5. 2011-07-12. PMID:18928587. |
then the proliferation of nb4 and mr2 cells was determined by mtt assay, the morphologic changes of cells were evaluated by wright's staining, the apoptosis rates were detected by flow cytometry. |
2011-07-12 |
2023-08-12 |
Not clear |
| Ya-Ru Wang, Shu-Peng Wen, Fu-Xu Wang, Li Wen, Bo-Yan Yang, Jing-Ci Yang, Xue-Jun Zhang, Shi-Fang Yan. [Apoptosis of the adriamycin-resistant leukemia cell line induced by the recombinant mutant human TNF-related apoptosis-inducing ligand combined with arsenic trioxide]. Zhongguo shi yan xue ye xue za zhi. vol 16. issue 5. 2011-07-12. PMID:18928594. |
the morphologic changes of cells treated with rmhtrail were observed by inverted microscope, taking adriamycin-sensitive cell line k562 (mdr-1(-)) as control; the inhibitory rate of cell proliferation after being treated with rmhtrail, as(2)o(3) alone or combined was assayed by mtt method; the apoptosis peaks of k562/ao2 and k562 were quantitatively detected by flow cytometry with pi staining after being treated with rmhtrail, as(2)o(3) alone or in combination. |
2011-07-12 |
2023-08-12 |
human |
| Zhen-Chuan Shang, Ting-Ting Song, Yang-Tang Hou, Li Fu, Tao Deng, Hai Yi, Tao Zhang, Bing-Zhong Su. [Role of mitochondria pathway in signal transduction of chronic myeloid leukemia]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379550. |
after bcr3/abl2 antisense oligodeoxynucleotide (aso) was introduced into cml cell line k562 cells by liposomal transfection, the cell viability was detected by mtt assay, the cell apoptosis was determined by flow cytometry (fcm), the mitochondrial membrane potential (deltapsi) was labeled by rhodamine 123 and examined by fcm, and the expression of mitochondrial apoptosis signal transduction pathway related proteins cytochrome c was analyzed by western blot. |
2011-07-12 |
2023-08-12 |
Not clear |