| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yao Zhao, Chun-lin Zhang, Bing-fang Zeng, Xiao-san Wu, Tian-tian Gao, Yoshino Od. Enhanced chemosensitivity of drug-resistant osteosarcoma cells by lentivirus-mediated Bcl-2 silencing. Biochemical and biophysical research communications. vol 390. issue 3. 2009-12-29. PMID:19818735. |
flow cytometry and mtt assays revealed that bcl-2 knock-down increased cellular apoptosis and the mg63 cells became sensitive to doxorubicin. |
2009-12-29 |
2023-08-12 |
human |
| Qiong Wang, Min Liu, Xin Li, Lu Chen, Hua Tan. Kazrin F is involved in apoptosis and interacts with BAX and ARC. Acta biochimica et biophysica Sinica. vol 41. issue 9. 2009-12-17. PMID:19727525. |
knockdown of kazrin f using sirna caused cell apoptosis and a marked decrease in cell viability measured by mtt and tunel assays. |
2009-12-17 |
2023-08-12 |
Not clear |
| Y Deng, C Lin, J Zheng, X Liang, J Chen, M Fu, P Xiao, M W. Mechanisms of arsenic trioxide induced apoptosis of human cervical cancer HeLa cells and protection by Bcl-2. Science in China. Series C, Life sciences. vol 42. issue 6. 2009-12-16. PMID:18726487. |
by mtt and colony forming ability assays, morphology alteration, flow cytometric analysis, dna gel electrophoresis and in situ cell death detection (tunel), it was found that as(2)o(3) inhibited the growth of hela cells and induced g2/m arrest and apoptosis of the cells. |
2009-12-16 |
2023-08-12 |
human |
| Jun-Ling Liu, Rong-Xi Yu, Jun-Fa Che. [Apoptosis of HL-60 cells induced by artesunate in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 3. 2009-12-11. PMID:17605854. |
the inhibition of art on hl-60 cells were evaluated by means of mtt assay; cell apoptosis was detected by light microscopy, agarose gel electro-phoresis, flow cytometry; western blot was used to analyze the expression of bcl-2 and icad in cells during apoptosis induced by art. |
2009-12-11 |
2023-08-12 |
Not clear |
| Guo-Rui Ruan, Shan-Shan Chen, Yan Chang, Jin-Lan Li, Ya-Zhen Qin, Ling-Di Li, Le Hao, Jia-Yu Fu, Yan-Rong Liu, Xiao-Jun Huan. [Adenovirus-mediated PDCD5 gene transfer sensitizes apoptosis of K562 cells induced by etoposide]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 5. 2009-12-11. PMID:17956665. |
the effects of etoposide in combination with ad-pdcd5 on the proliferation and apoptosis of k562 cells were measured by using mtt assay and flow cytometry with annexin-v-fitc/pi dual labeling technique, respectively. |
2009-12-11 |
2023-08-12 |
Not clear |
| Qing-Hong Yu, Rong Zhan, Hao-Bo Huan. [Mechanisms underlying the effect of arsenic trioxide on proliferation inhibition and apoptosis induction in myeloma cell line u266]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 5. 2009-12-11. PMID:17956674. |
the viability and apoptosis of u266 cells were observed by mtt assay, flow cytometry and dna agarose gel electrophoresis. |
2009-12-11 |
2023-08-12 |
Not clear |
| Hui-Hui Zhao, Bao-An Chen, Chong Gao, Ze-Ye Shao, Guo-Hua Xia, Jia-Hua Ding, Yun-Yu Sun, Jun Wang, Jian Cheng, Gang Zhao, K Dohner, H Dohne. [Apoptosis of human myelodysplastic syndrome cell Line MUTZ-1 induced by sodium valproate]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 4. 2009-12-08. PMID:17708795. |
the cell proliferation was determined by mtt assay, apoptotic morphological features were observed by light microscopy and transmission electronmicroscopy, cell apoptosis and cell cycle shift were analyzed by flow cytometry (fcm). |
2009-12-08 |
2023-08-12 |
human |
| Jing Cui, Jing Ding, Yi-Ping Wu, Fu-Qiang Liu, Xiao-Chao Liu, Yang Wan. [Reversal effect of sodium selenite on multidrug resistance in K562/ADR cell line and its mechanisms]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 4. 2009-12-08. PMID:17708798. |
the cytotoxicity and the reversal effect of sodium selenite on k562/adr cells were assayed by mtt method; the apoptosis rate of k562 and k562/adr cells were detected by flow cytometery, the mrna expressions of mdr1 and bcl-2 were measured by semi-quantitative reverse transcriptase polymerase chain reaction (rt-pcr). |
2009-12-08 |
2023-08-12 |
Not clear |
| Bo Liu, Qing-Xian Bai, Xie-Qun Chen, Guang-Xun Gao, Hong-Tao G. [Effect of curcumin on expression of survivin, Bcl-2 and Bax in human multiple myeloma cell line]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 4. 2009-12-08. PMID:17708799. |
to explore the mechanisms of suppression growth and induction apoptosis of curcumin on human multiple myeloma cell line rpmi8226, the suppressive effect of curcumin on rpmi8226 was examined by mtt assay; the induction apoptosis and cell cycle arrest of curcumin on rpmi8226 were determined by flow cytometry (fcm); the changes of survivin, bcl-2, bax mrna levels were detected by rt-pcr. |
2009-12-08 |
2023-08-12 |
human |
| Ling Sun, Yi-Hao Wang, Shao-Jun Liu, Fang Wang, Hong-Yan Ma, Hui Sun, Yu-Ren X. [Effect of vascular endothelial growth factor antisense oligonucleotide on human leukemic cell line HL-60]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 4. 2009-12-08. PMID:17708817. |
the phosphorothiate vegf odn was transferred into hl-60 cells in vitro by using cation poly mediated method, the inhibitory rate of cell proliferation was assayed by mtt, expression of vegf mrna was measured by rt-pcr, cell apoptosis was detected by cell morphology observation, dna agarose gel electrophoresis and flow cytometer (fcm). |
2009-12-08 |
2023-08-12 |
human |
| Yue-Jiao Zhong, Bao-An Chen, Cheng-Yin Huang, Cui-Ping Li, Feng Gao, Fei Fei, Xiao-Ping Pei, Chong Gao, Jia-Hua Ding, Yun-Yu Sun, Jian Cheng, Jun Wang, Gang Zhao, Yan M. [Effects of platelet-derived membrane microparticles on the proliferation and apoptosis of human umbilical vein endothelial cells]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 4. 2009-12-08. PMID:17708819. |
by using the huvec cultivated in vitro as vector, the effects of pmps on the proliferation and apoptosis of huvec were investigated by mtt and fcm. |
2009-12-08 |
2023-08-12 |
human |
| Guangxiang Zang, Leiying Miao, Yabing Mu, Chunyan Qiao, Jinzhong Liu, Xiaoliang Ke, Changyu Zheng, Hongchen Su. Adenoviral mediated transduction of adenoid cystic carcinoma by human TRAIL gene driven with hTERT tumor specific promoter induces apoptosis. Cancer biology & therapy. vol 8. issue 10. 2009-12-07. PMID:19587531. |
transduction of sacc-83, but not of control human embryo-fibrocyte lung (hel) cells, led to apoptosis as measured by mtt assay and flow cytomerty. |
2009-12-07 |
2023-08-12 |
human |
| C S Rejiya, T R Cibin, Annie Abraha. Leaves of Cassia tora as a novel cancer therapeutic--an in vitro study. Toxicology in vitro : an international journal published in association with BIBRA. vol 23. issue 6. 2009-11-30. PMID:19540331. |
proliferation of hela was measured by mtt assay, cell dna content by modified diphenylamine method and apoptosis by caspase 3 activity. |
2009-11-30 |
2023-08-12 |
human |
| Xia Qian, Jing Li, Jianhua Ding, Zhiyuan Wang, Wenjing Zhang, Gang H. Erlotinib activates mitochondrial death pathways related to the production of reactive oxygen species in the human non-small cell lung cancer cell line A549. Clinical and experimental pharmacology & physiology. vol 36. issue 5-6. 2009-11-24. PMID:19673930. |
the 3-(4,5-dimethyl-2 thiazoyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) assay and hoechst 33342 staining showed that erlotinib produced a decline in cell viability of a549 cells and induced cell apoptosis, coupled with quick accumulation of ros. |
2009-11-24 |
2023-08-12 |
human |
| Myung Jin Kim, Hyung Il Kim, Jin Chung, Tae Sung Jeong, Hae Ryoun Par. (-)-Epigallocatechin-3-gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt. The American journal of Chinese medicine. vol 37. issue 4. 2009-11-16. PMID:19655410. |
a mtt assay showed that egcg significantly increased the viability of serum-starved a549 cells compared to the control cells, though egcg at high concentration (approximately 300 microm) had no protective effect against serum withdrawal-induced cell apoptosis. |
2009-11-16 |
2023-08-12 |
Not clear |
| Hak Hyun Jung, Hyung Jin Kim, Gi Jung Im, Jiwon Chang, June Choi, Sung Won Cha. Differential protein expression profiles in salicylate ototoxicity of the mouse cochlea. Hearing research. vol 255. issue 1-2. 2009-11-04. PMID:19540324. |
we also confirmed the ototoxicity of salicylate in organotypic culture of cochlear cells using mtt assay, hoechst staining and dna laddering assay in vitro, and found that salicylate decreased the viability of cells in a time and dose-dependent manner, and that induced apoptosis in organotypic culture of cochlear cells. |
2009-11-04 |
2023-08-12 |
mouse |
| Gennaro Riccio, Giovanni Esposito, Emanuela Leoncini, Riccardo Contu, Gianluigi Condorelli, Massimo Chiariello, Paolo Laccetti, Silvana Hrelia, Giuseppe D'Alessio, Claudia De Lorenz. Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 23. issue 9. 2009-10-23. PMID:19417081. |
toxicity and apoptosis were tested in vitro by 3-(4,5-dimethyl-2-thizolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt), dna fragmentation, and immunoblotting analyses. |
2009-10-23 |
2023-08-12 |
mouse |
| Fan Yuan-Jing, Huang Nan-Shan, Xia Lia. Genistein synergizes with RNA interference inhibiting survivin for inducing DU-145 of prostate cancer cells to apoptosis. Cancer letters. vol 284. issue 2. 2009-10-20. PMID:19433345. |
to further investigate the effect of a combination of genistein with survivin of rna interference on the proliferation and apoptosis of du-145 cells, the effect of genistein on the proliferation of du-145 cells was detected by the mtt method and cytometry, and the apoptosis of cells was observed with fluorescence microscopy. |
2009-10-20 |
2023-08-12 |
Not clear |
| Sebastian Knauer, Bernhard Biersack, Miroslava Zoldakova, Katharina Effenberger, Wolfgang Milius, Rainer Schober. Melanoma-specific ferrocene esters of the fungal cytotoxin illudin M. Anti-cancer drugs. vol 20. issue 8. 2009-10-16. PMID:19606019. |
esters of illudin m with ferrocenoic and 1,1'-ferrocenedioic acid were prepared, structurally characterised (x-ray), and tested for cytotoxicity [mtt assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], induction of apoptosis (tunel assay; western blotting for caspase-9), and tumor specificity in cells of human hl-60 leukemia, human 518a2 melanoma, and in nonmalignant human foreskin fibroblasts. |
2009-10-16 |
2023-08-12 |
human |
| Ka Chen, Qianyong Zhang, Jian Wang, Fengjin Liu, Mantian Mi, Hongxia Xu, Fang Chen, Kaihong Zen. Taurine protects transformed rat retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction. Brain research. vol 1279. 2009-09-30. PMID:19427840. |
pretreatment of rgc-5 cells with 0.1 mm taurine significantly reduced the extent of apoptosis detected by dapi staining, mtt, and annexin v-fitc/pi assays. |
2009-09-30 |
2023-08-12 |
rat |